Virus, Immunology and Pathogenesis


Description of a new biosafe procedure for cytological specimens from patients with COVID-19 processed by liquid-based preparations

Straccia P, Rossi ED, Martini M, Mulè A, Cianfrini F, Curatolo M, Cancellieri A, Brunelli C, Zannoni GF, Fadda G.

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ACE polymorphism and COVID-19 outcome

Delanghe JR, Speeckaert MM, De Buyzere ML.

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Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M(pro) and cathepsin L

Sacco MD, Ma C, Lagarias P, Gao A, Townsend JA, Meng X, Dube P, Zhang X, Hu Y, Kitamura N, Hurst B, Tarbet B, Marty MT, Kolocouris A, Xiang Y, Chen Y, Wang J.

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Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories

Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, Xu A, Li J, Dong S, Rothchild A, Zhou J, Murray K, Edmark R, Hong S, Jones L, Zhou Y, Roper R, Mackay S, O'Mahony DS, Dale CR, Wallick JA, Algren HA, Michael ZA, Magis A, Wei W, Price ND, Huang S, Subramanian N, Wang K, Hadlock J, Hood L, Aderem A, Bluestone JA, Lanier LL, Greenberg P, Gottardo R, Davis MM, Goldman JD, Heath JR.

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A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors

Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR.

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Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals

Doddapaneni H, Cregeen SJ, Sucgang R, Meng Q, Qin X, Avadhanula V, Chao H, Menon V, Nicholson E, Henke D, Piedra FA, Rajan A, Momin Z, Kottapalli K, Hoffman KL, Sedlazeck FJ, Metcalf G, Piedra PA, Muzny DM, Petrosino JF, Gibbs RA.

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Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction

Cao W, Dong C, Kim S, Hou D, Tai W, Du L, Im W, Zhang XF.

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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

Jacob F, Pather SR, Huang WK, Wong SZH, Zhou H, Zhang F, Cubitt B, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, de A Torre JC, Ming GL.

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A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

Sun W, McCroskery S, Liu WC, Leist SR, Liu Y, Albrecht RA, Slamanig S, Oliva J, Amanat F, Schaefer A, Dinnon KH, Innis BL, Garcia-Sastre A, Krammer F, Baric RS, Palese P.

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In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19

Br B, Damle H, Ganju S, Damle L.

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Genus-specific pattern of intrinsically disordered central regions in the nucleocapsid protein of coronaviruses

Barik S.

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Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein

Xing Y, Li X, Gao X, Dong Q.

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Wide Diversity of Coronaviruses in Frugivorous and Insectivorous Bat Species: A Pilot Study in Guinea, West Africa

Lacroix A, Vidal N, Keita AK, Thaurignac G, Esteban A, De Nys H, Diallo R, Toure A, Goumou S, Soumah AK, Povogui M, Koivogui J, Monemou JL, Raulino R, Nkuba A, Foulongne V, Delaporte E, Ayouba A, Peeters M.

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Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

Porretta AD, Baggiani A, Arzilli G, Casigliani V, Mariotti T, Mariottini F, Scardina G, Sironi D, Totaro M, Barnini S, Privitera GP.

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Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

Kang YL, Chou YY, Rothlauf PW, Liu Z, Soh TK, Cureton D, Case JB, Chen RE, Diamond MS, Whelan SPJ, Kirchhausen T.

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Genome Sequences of Six SARS-CoV-2 Strains Isolated in Morocco, Obtained Using Oxford Nanopore MinION Technology

Laamarti M, Chemao-Elfihri MW, Kartti S, Laamarti R, Allam L, Ouadghiri M, Smyej I, Rahoui J, Benrahma H, Diawara I, Alouane T, Essabbar A, Siah S, Karra M, El Hafidi N, El Jaoudi R, Sbabou L, Nejjari C, Amzazi S, Mentag R, Belyamani L, Ibrahimi A.

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The D614G substitution in the S gene and clinical information for patients with COVID-19 detected in Hong Kong

Mak GCK, Lau AWL, Chan AMY, Chan DYW, Tsang DNC.

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A systematic review of re-detectable positive virus nucleic acid among COVID-19 patients in recovery phase

Gao Z, Xu Y, Guo Y, Xu D, Zhang L, Wang X, Sun C, Qiu S, Ma K.

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In silico virtual screening, characterization, docking and molecular dynamics studies of crucial SARS-CoV-2 proteins

Alazmi M, Motwalli O.

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In silico investigation of phytoconstituents from Indian medicinal herb 'Tinospora cordifolia (giloy)' against SARS-CoV-2 (COVID-19) by molecular dynamics approach

Chowdhury P.

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Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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Circulating endothelial progenitors are increased in Covid-19 patients and correlate with SARS-CoV-2 RNA in severe cases

Mancuso P, Gidaro A, Gregato G, Raveane A, Cremonesi P, Quarna J, Caccia S, Gusso L, Rusconi S, Giacomelli A, Cogliati C, Bertolini F.

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Potential Zoonotic Origins of SARS-CoV-2 and Insights for Preventing Future Pandemics Through One Health Approach

Konda M, Dodda B, Konala VM, Naramala S, Adapa S.

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Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations

Ortiz-Fern√°ndez L, Sawalha AH.

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Dysregulated adaptive immune response contributes to severe COVID-19

Yu K, He J, Wu Y, Xie B, Liu X, Wei B, Zhou H, Lin B, Zuo Z, Wen W, Xu W, Zou B, Wei L, Huang X, Zhou P.

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Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection

Gand M, Vanneste K, Thomas I, Van Gucht S, Capron A, Herman P, Roosens NHC, De Keersmaecker SCJ.

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Role of cytotoxic T lymphocytes and interferon-γ in coronavirus infection: lessons from murine coronavirus infections in mice

Kyuwa S, Sugiura Y.

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Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

Skendros P, Mitsios A, Chrysanthopoulou A, Mastellos DC, Metallidis S, Rafailidis P, Ntinopoulou M, Sertaridou E, Tsironidou V, Tsigalou C, Tektonidou MG, Konstantinidis T, Papagoras C, Mitroulis I, Germanidis G, Lambris JD, Ritis K.

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Unique fibrinogen-binding motifs in the nucleocapsid phosphoprotein of SARS CoV-2: Potential implications in host-pathogen interactions

Sangith N.

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In silico molecular docking analysis for repurposing therapeutics against multiple proteins from SARS-CoV-2

Deshpande RR, Tiwari AP, Nyayanit N, Modak M.

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In silico Potential of Approved Antimalarial Drugs for Repurposing Against COVID-19

Sachdeva C, Wadhwa A, Kumari A, Hussain F, Jha P, Kaushik NK.

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Gold nanoparticles against respiratory diseases: oncogenic and viral pathogens review

V R, Pal K, Zaheer T, Kalarikkal N, Thomas S, de Souza FG, Si A.

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Intra- and intermolecular atomic-scale interactions in the receptor binding domain of SARS-CoV-2 spike protein: implication for ACE2 receptor binding

Adhikari P, Li N, Shin M, Steinmetz NF, Twarock R, Podgornik R, Ching WY.

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Discovery of sandwich type COVID-19 nucleocapsid protein DNA aptamers

Zhang L, Fang X, Liu X, Ou H, Zhang H, Wang J, Li Q, Cheng H, Zhang W, Luo Z.

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Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain

Bernardi A, Huang Y, Harris B, Xiong Y, Nandi S, McDonald KA, Faller R.

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Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

Choudhary S, Malik YS, Tomar S.

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Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation

McCallum M, Walls AC, Bowen JE, Corti D, Veesler D.

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Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein

Singh B.

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Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients

Andres C, Garcia-Cehic D, Gregori J, Piñana M, Rodriguez-Frias F, Guerrero-Murillo M, Esperalba J, Rando A, Goterris L, Codina MG, Quer S, Martín MC, Campins M, Ferrer R, Almirante B, Esteban JI, Pumarola T, Antón A, Quer J.

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Food and COVID-19: Preventive/Co-therapeutic Strategies Explored by Current Clinical Trials and in Silico Studies

Di Matteo G, Spano M, Grosso M, Salvo A, Ingallina C, Russo M, Ritieni A, Mannina L.

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SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease

Perera RAPM, Tso E, Tsang OTY, Tsang DNC, Fung K, Leung YWY, Chin AWH, Chu DKW, Cheng SMS, Poon LLM, Chuang VWM, Peiris M.

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Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference

Zhang Y, Wang C, Han M, Ye J, Gao Y, Liu Z, He T, Li T, Xu M, Zhou L, Zou G, Lu M, Zhang Z.

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Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

Huang Y, Yang C, Xu XF, Xu W, Liu SW.

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Antibody response against SARS-CoV-2 spike protein and nucleoprotein evaluated by 4 automated immunoassays and 3 ELISAs

Van Elslande J, Decru B, Jonckheere S, Van Wijngaerden E, Houben E, Vandecandelaere P, Indevuyst C, Depypere M, Desmet S, André E, Van Ranst M, Lagrou K, Vermeersch P.

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Kinetics and Isotype Assessment of Antibodies Targeting the Spike Protein Receptor Binding Domain of SARS-CoV-2 In COVID-19 Patients as a function of Age and Biological Sex

Graham NR, Whitaker AN, Strother CA, Miles AK, Grier D, McElvany BD, Bruce EA, Poynter ME, Pierce KK, Kirkpatrick BD, Stapleton RD, An G, Botten JW, Crothers JW, Diehl SA.

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CoVaccine HT‚Ñ¢ adjuvant potentiates robust immune responses to recombinant SARS-CoV-2 Spike S1 immunisation

Haun BK, Lai CY, Williams CA, Wong TA, Lieberman MM, Pessaint L, Andersen-Elyard H, Lehrer AT.

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The SARS-CoV-2 Spike Variant D614G Favors an Open Conformational State

Mansbach RA, Chakraborty S, Nguyen K, Montefiori D, Korber B, Gnanakaran S.

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Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L.

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Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

Sun W, Leist SR, McCroskery S, Liu Y, Slamanig S, Oliva J, Amanat F, Schaefer A, Dinnon K, Garcia-Sastre A, Krammer F, Baric RS, Palese P.

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RdRp mutations are associated with SARS-CoV-2 genome evolution

Eskier D, Karakülah G, Suner A, Oktay Y.

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, Olivera de Souza M, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L.

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In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy

Wei TZ, Wang H, Wu XQ, Lu Y, Guan SH, Dong FQ, Dong CL, Zhu GL, Bao YZ, Zhang J, Wang GY, Li HY.

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In silico ADMET and molecular docking study on searching potential inhibitors from limonoids and triterpenoids for COVID-19

Vardhan S, Sahoo SK.

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In silico Study of Azithromycin, Chloroquine and Hydroxychloroquine and their Potential Mechanisms of Action against SARS-CoV-2 Infection

Braz HLB, de Moraes Silveira JA, Marinho AD, de Moraes MEA, de Moraes Filho MO, Monteiro HSA, Jorge RJB.

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Prospective study comparing deep-throat saliva with other respiratory tract specimens in the diagnosis of novel coronavirus disease (COVID-19)

Lai CKC, Chen Z, Lui G, Ling L, Li T, Wong MCS, Ng RWY, Tso EYK, Ho T, Fung KSC, Ng ST, Wong BKC, Boon SS, Hui DSC, Chan PKS.

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A thermostable, closed SARS-CoV-2 spike protein trimer

Xiong X, Qu K, Ciazynska KA, Hosmillo M, Carter AP, Ebrahimi S, Ke Z, Scheres SHW, Bergamaschi L, Grice GL, Zhang Y; CITIID-NIHR COVID-19 BioResource Collaboration, Nathan JA, Baker S, James LC, Baxendale HE, Goodfellow I, Doffinger R, Briggs JAG.

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Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2

Lee SH, Jee SW, Hwang DY, Kang JK.

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Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

Gu H, Chen Q, Yang G, He L, Fan H, Deng YQ, Wang Y, Teng Y, Zhao Z, Cui Y, Li Y, Li XF, Li J, Zhang NN, Yang X, Chen S, Guo Y, Zhao G, Wang X, Luo DY, Wang H, Yang X, Li Y, Han G, He Y, Zhou X, Geng S, Sheng X, Jiang S, Sun S, Qin CF, Zhou Y.

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Genome Sequences of SARS-CoV-2 Strains Detected in Hong Kong

Au CH, Chan WS, Lam HY, Ho DN, Lam SYM, Zee JST, Chan TL, Ma ESK.

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Reports of Coding-Complete Genome Sequences of Five 2019 Novel Coronavirus (SARS-CoV-2) Strains Isolated in Bangladesh

Khan MI, Hasan KN, Sufian A, Hosen MB, Polol MNI, Khaleque MA, Rahman MM, Chowdhury MSM, Haider HU, Razu MH, Khan M, Rabbi MF.

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Vaccine Design from the Ensemble of Surface Glycoprotein Epitopes of SARS-CoV-2: An Immunoinformatics Approach

Rahman N, Ali F, Basharat Z, Shehroz M, Khan MK, Jeandet P, Nepovimova E, Kuca K, Khan H.

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Structure-based drug repositioning over the human TMPRSS2 protease domain: search for chemical probes able to repress SARS-CoV-2 Spike protein cleavages

Singh N, Decroly E, Khatib AM, Villoutreix BO.

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The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

Li Q, Wu J, Nie J, Zhang L, Hao H, Liu S, Zhao C, Zhang Q, Liu H, Nie L, Qin H, Wang M, Lu Q, Li X, Sun Q, Liu J, Zhang L, Li X, Huang W, Wang Y.

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The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing

Xavier J MSc, Giovanetti M PhD, Adelino T MSc, Fonseca V MSc, da Costa AVB BSc, Ribeiro AA BSc, Felicio KN, Duarte CG PhD, Silva MVF PhD, Salgado Á MSc, Lima MT PhD, de Jesus R MSc, Fabri A MSc, Zoboli CFS BSc, Santos TGS, Iani F MSC, Ciccozzi M PhD, de Filippis AMB PhD, de Siqueira MAMT PhD, de Abreu AL MSc, de Azevedo V PhD, Ramalho DB BSc, de Albuquerque CFC MSc, de Oliveira T Phd, Holmes EC PhD, Lourenço J PhD, Alcantara LCJ PhD, Oliveira MAA PhD.

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Quantitative determination of mechanical stability in the novel coronavirus spike protein

Moreira RA, Chwastyk M, Baker JL, Guzman HV, Poma AB.

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Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection

Moreau GB, Burgess SL, Sturek JM, Donlan AN, Petri WA, Mann BJ.

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In silico Drug Repurposing for COVID-19: Targeting SARS-CoV-2 Proteins through Docking and Consensus Ranking

Cavasotto C, Di Filippo J.

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In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection

Martorana A, Gentile C, Lauria A.

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Recombinant protein targeting and opsonizing spike glycoprotein for enhancing SARS-CoV-2 phagocytosis

Khattabi L.

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A Computational Approach to Identify Potential Novel Inhibitors against the Coronavirus SARS-CoV-2

Battisti V, Wieder O, Garon A, Seidel T, Urban E, Langer T.

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Relationship Between serum SARS-CoV-2 nucleic acid(RNAemia) and Organ Damage in COVID-19 Patients: A Cohort Study

Xu D, Zhou F, Sun W, Chen L, Lan L, Li H, Xiao F, Li Y, Kolachalama VB, Li Y, Wang X, Xu H.

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In silico study to evaluate the antiviral activity of novel structures against 3C-like protease of Novel Coronavirus (COVID-19) and SARS-CoV

Chunduru K, Sankhe R, Begum F, Sodum N, Kumar N, Kishore A, Shenoy RR, Rao CM, Saravu K.

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Identification of some novel oxazine substituted 9-anilinoacridines as SARS-CoV-2 inhibitors for COVID-19 by molecular docking, free energy calculation and molecular dynamics studies

Rajagopal K, Varakumar P, Aparna B, Byran G, Jupudi S.

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Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA-dependent RNA polymerase (RdRp) inhibition: an in-silico analysis

Singh S, Sk MF, Sonawane A, Kar P, Sadhukhan S.

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Dynamic Changes of Antibodies to SARS-CoV-2 in COVID-19 Patients at Early Stage of Outbreak

Shu H, Wang S, Ruan S, Wang Y, Zhang J, Yuan Y, Liu H, Wu Y, Li R, Pan S, Ouyang Y, Yuan S, Zhou P, Shang Y.

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Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species

Cao Y, Sun Y, Tian X, Bai Z, Gong Y, Qi J, Liu D, Liu W, Li J.

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Current Findings Regarding Natural Components With Potential Anti-2019-nCoV Activity

Zhou J, Huang J.

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Cell-Mediated Immune Responses to COVID-19 Infection

Guihot A, Litvinova E, Autran B, Debré P, Vieillard V.

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Establishing a Unified COVID-19 "Immunome": Integrating Coronavirus Pathogenesis and Host Immunopathology

Wauters E, Thevissen K, Wouters C, Bosisio FM, De Smet F, Gunst J, Humblet-Baron S, Lambrechts D, Liston A, Matthys P, Neyts J, Proost P, Weynand B, Wauters J, Tejpar S, Garg AD.

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Severe Acute Respiratory Syndrome Coronavirus 2: From Gene Structure to Pathogenic Mechanisms and Potential Therapy

Wu J, Yuan X, Wang B, Gu R, Li W, Xiang X, Tang L, Sun H.

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Identification of key interactions between SARS-CoV-2 main protease and inhibitor drug candidates

Yoshino R, Yasuo N, Sekijima M.

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Immune response in COVID-19: A review

Chowdhury MA, Hossain N, Kashem MA, Shahid MA, Alam A.

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Covid-19-Related Endothelial Injury in Lung Cryobiopsy

Ruiz de Gopegui Miguelena P, Peiro Chamarro M, Claraco Vega LM.

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In Silico Identification of a Potent Arsenic Based Approved Drug Darinaparsin against SARS-CoV-2: Inhibitor of RNA Dependent RNA polymerase (RdRp) and Essential Proteases

Chowdhury T, Roymahapatra G, Mandal SM.

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Potential Anti-COVID-19 Therapeutics that Block the Early Stage of the Viral Life Cycle: Structures, Mechanisms, and Clinical Trials

Al-Horani RA, Kar S, Aliter KF.

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Immunogenic SARS-CoV-2 Epitopes: In Silico Study Towards Better Understanding of COVID-19 Disease-Paving the Way for Vaccine Development

Ranga V, Niemelä E, Tamirat MZ, Eriksson JE, Airenne TT, Johnson MS.

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Pt-, Rh-, Ru-, and Cu-Single-Wall Carbon Nanotubes Are Exceptional Candidates for Design of Anti-Viral Surfaces: A Theoretical Study

Aasi A, Aghaei SM, Moore MD, Panchapakesan B.

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Enzymatic Protein Biopolymers as a Tool to Synthetize Eukaryotic Messenger Ribonucleic Acid (mRNA) with Uses in Vaccination, Immunotherapy and Nanotechnology

Urbina F, Morales-Pison S, Maldonado E.

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Longitudinal analyses reveal immunological misfiring in severe COVID-19

Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, Mohanty S, Wang H, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Muenker MC, Fournier JB, Campbell M, Odio CD, Casanovas-Massana A; Yale IMPACT Team, Herbst R, Shaw AC, Medzhitov R, Schulz WL, Grubaugh ND, Dela Cruz C, Farhadian S, Ko AI, Omer SB, Iwasaki A.

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Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy

Mohammad T, Shamsi A, Anwar S, Hussain A, Rehman MT, AlAjmi MF, Islam A, Hassan MI.

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Immunological co-ordination between gut and lungs in SARS-CoV-2 infection

Ahlawat S, Asha, Sharma KK.

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Genomics approaches to synthesis plant-based biomolecules for therapeutic applications to combat SARS-CoV-2

Sharma N, Muthamilarasan M, Prasad A, Prasad M.

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The Lord of the NanoRings: cyclodextrins and the battle against SARS-CoV-2

Garrido PF, Calvelo M, Blanco-González A, Veleiro U, Suárez F, Conde D, Cabezón A, Piñeiro Á, Garcia-Fandino R.

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The Novel Insight of SARS-CoV-2 Molecular Biology and Pathogenesis and Therapeutic Options

Asghari A, Naseri M, Safari H, Saboory E, Parsamanesh N.

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Virtual screening, ADMET prediction and dynamics simulation of potential compounds targeting the main protease of SARS-CoV-2

Yadav R, Imran M, Dhamija P, Chaurasia DK, Handu S.

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Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?

Nawijn MC, Timens W.

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SARS-CoV-2 Whole Genome Amplification and Sequencing for Effective Population-Based Surveillance and Control of Viral Transmission

Harilal D, Ramaswamy S, Loney T, Al Suwaidi H, Khansaheb H, Alkhaja A, Varghese R, Deesi Z, Nowotny N, Alsheikh-Ali A, Tayoun AA.

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Mouse Model of SARS-CoV-2 Reveals Inflammatory Role of Type I Interferon Signaling

Goldman-Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer R, Ring A, Wilen C, Iwasaki A.

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The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2

Di Gioacchino A, Sulc P, Komarova AV, Greenbaum BD, Monasson R, Cocco S.

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Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis

Kumar N, Mishra B, Mehmood A, Athar M, Mukhtar MS.

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Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site

Jaimes J, Millet J, Whittaker G.

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Candidate Targets for Immune Responses to 2019-Novel Coronavirus (nCoV): Sequence Homology- and Bioinformatic-Based Predictions

Grifoni A, Sidney J, Zhang Y, Scheuermann RH, Peters B, Sette A.

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Risks of Zoonotic Transmission of COVID-19 during Eid-Ul-Adha in Pakistan

Mallhi TH, Khan YH, Butt MH, Liaqat A, Abid A, Ahmad A, Misbah S.

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Viral Evolution will Automatically Resolve COVID-19 Pandemic

Sharma D.

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Understanding COVID-19 via comparative analysis of dark proteomes of SARS-CoV-2, human SARS and bat SARS-like coronaviruses

Giri R, Bhardwaj T, Shegane M, Gehi BR, Kumar P, Gadhave K, Oldfield CJ, Uversky VN.

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COVID-19: Critical Role of Angiotensin 1-7 in ACE2 Modulation

Tan CS, Yeoh SF, Long CM.

Abstract:

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Inflammatory Markers in COVID-19

Bhandari S, Sharma S, Bhargava A, Keswani P, Sharma R, Shekhawat A.

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COVID-19: immunopathogenesis and Immunotherapeutics

Yang L, Liu S, Liu J, Zhang Z, Wan X, Huang B, Chen Y, Zhang Y.

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Decoding the proteome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for cell-penetrating peptides involved in pathogenesis or applicable as drug delivery vectors

Hemmati S, Behzadipour Y, Haddad M.

Abstract:

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Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2

Manna S, Baindara P, Mandal SM.

Abstract:

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Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae

Ma Z, Li Z, Dong L, Yang T, Xiao S.

Abstract:

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Geogenic arsenic removal through core-shell based functionalized nanoparticles: Groundwater in-situ treatment perspective in the post-COVID anthropocene

Raval NP, Kumar M.

Abstract:

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Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

Amrun SN, Lee CY, Lee B, Fong SW, Young BE, Chee RS, Yeo NK, Torres-Ruesta A, Carissimo G, Poh CM, Chang ZW, Tay MZ, Chan YH, Chen MI, Low JG, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Leo YS, Lye DC, Renia L, Ng LFP.

Abstract:

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Viable SARS-CoV-2 in various specimens from COVID-19 patients

Jeong HW, Kim SM, Kim HS, Kim YI, Kim JH, Cho JY, Kim SH, Kang H, Kim SG, Park SJ, Kim EH, Choi YK.

Abstract:

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Mutations Strengthened SARS-CoV-2 Infectivity

Chen J, Wang R, Wang M, Wei GW.

Abstract:

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Biochemical Dynamics and Clinical Features of Novel Corona Virus (2019-nCoV)

Nazir T, Nazir SUR, Sultana M, Taha N, Riaz H, Islam A, Rasheed Kayani R, Manzoor S.

Abstract:

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Antibody responses to SARS-CoV-2 in healthy individuals returning to Shenzhen

Zhang C, Lin L, Tang D, Liu F, Li M, Li Q, Deng Z, Chu G, Gu D, Dai Y.

Abstract:

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Angiotensin converting enzyme 2 at the interface between renin-angiotensin system inhibition and coronavirus disease 2019

Siri-Angkul N, Chattipakorn SC, Chattipakorn N.

Abstract:

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Preliminary Analysis of B- and T-Cell Responses to SARS-CoV-2

Zhang LX, Miao SY, Qin ZH, Wu JP, Chen HY, Sun HB, Xie Y, Du YQ, Shen J.

Abstract:

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Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

Krafcikova P, Silhan J, Nencka R, Boura E.

Abstract:

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Structural basis of RNA cap modification by SARS-CoV-2

Viswanathan T, Arya S, Chan SH, Qi S, Dai N, Misra A, Park JG, Oladunni F, Kovalskyy D, Hromas RA, Martinez-Sobrido L, Gupta YK.

Abstract:

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A simple solution to prevent microscope eyepiece fogging and spectacle fogging in COVID-19 era

Gurnani B, Kaur K, Mishra K, Venkatesh R.

Abstract:

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Digital eye strain in the era of COVID-19 pandemic: An emerging public health threat

Bhattacharya S, Saleem SM, Singh A.

Abstract:

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From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry

Kanduc D.

Abstract:

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Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm

Fakhouri EW, Peterson SJ, Kothari J, Alex R, Shapiro JI, Abraham NG.

Abstract:

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Defining the CD39/CD73 Axis in SARS-CoV-2 Infection: The CD73(-) Phenotype Identifies Polyfunctional Cytotoxic Lymphocytes

Ahmadi P, Hartjen P, Kohsar M, Kummer S, Schmiedel S, Bockmann JH, Fathi A, Huber S, Haag F, Schulze Zur Wiesch J.

Abstract:

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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK.

Abstract:

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Novel Temperature Trajectory Subphenotypes in COVID-19

Bhavani SV, Huang ES, Verhoef PA, Churpek MM.

Abstract:

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Inducible Epithelial Resistance Against Coronavirus Pneumonia in Mice

Evans SE, Tseng CK, Scott BL, Höök AM, Dickey BF.

Abstract:

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Detection profile of SARS-CoV-2 using RT-PCR in different types of clinical specimens: a systematic review and meta-analysis

Bwire GM, Majigo MV, Njiro BJ, Mawazo A.

Abstract:

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Presence of Genetic Variants Among Young Men With Severe COVID-19

van der Made CI, Simons A, Schuurs-Hoeijmakers J, van den Heuvel G, Mantere T, Kersten S, van Deuren RC, Steehouwer M, van Reijmersdal SV, Jaeger M, Hofste T, Astuti G, Corominas Galbany J, van der Schoot V, van der Hoeven H, Hagmolen Of Ten Have W, Klijn E, van den Meer C, Fiddelaers J, de Mast Q, Bleeker-Rovers CP, Joosten LAB, Yntema HG, Gilissen C, Nelen M, van der Meer JWM, Brunner HG, Netea MG, van de Veerdonk FL, Hoischen A.

Abstract:

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Molecular docking and dynamics study of natural compound for potential inhibition of main protease of SARS-CoV-2

Mahmud S, Uddin MAR, Zaman M, Sujon KM, Rahman ME, Shehab MN, Islam A, Alom MW, Amin A, Akash AS, Saleh MA.

Abstract:

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Identification of a potential SARS-CoV2 inhibitor via molecular dynamics simulations and amino acid decomposition analysis

Razzaghi-Asl N, Ebadi A, Shahabipour S, Gholamin D.

Abstract:

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In-Silico approach for identification of effective and stable inhibitors for COVID-19 main protease (M(pro)) from flavonoid based phytochemical constituents of Calendula officinalis

Das P, Majumder R, Mandal M, Basak P.

Abstract:

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Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors

Fiorucci D, Milletti E, Orofino F, Brizzi A, Mugnaini C, Corelli F.

Abstract:

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Collection and disinfection of forensic biological specimens in five cases concerning COVID-19 in Guangzhou, China

Yang X, Xu Q, Liu H, Xu J, Yang D, Xiao C, Hu H, Liu Y, Liu C.

Abstract:

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A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction

Tan CW, Chia WN, Qin X, Liu P, Chen MI, Tiu C, Hu Z, Chen VC, Young BE, Sia WR, Tan YJ, Foo R, Yi Y, Lye DC, Anderson DE, Wang LF.

Abstract:

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Human SARS-CoV-2 has evolved to reduce CG dinucleotide in its open reading frames

Wang Y, Mao JM, Wang GD, Luo ZP, Yang L, Yao Q, Chen KP.

Abstract:

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Can Dietary Fatty Acids Affect the COVID-19 Infection Outcome in Vulnerable Populations?

Onishi JC, Häggblom MM, Shapses SA.

Abstract:

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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, Le KC, Wrapp D, Lee AG, Liu Y, Chou CW, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Park J, Wang N, Amengor D, Lavinder JJ, Ippolito GC, Maynard JA, Finkelstein IJ, McLellan JS.

Abstract:

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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E.

Abstract:

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Perforin gene variant A91V in young patients with severe COVID-19

Cabrera-Marante O, Rodríguez de Frías E, Pleguezuelo DE, Allende LM, Serrano A, Laguna-Goya R, Mancebo ME, Talayero P, Álvarez-Vallina L, Morales P, Castro-Panete MJ, Paz-Artal E.

Abstract:

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Genetic variants that influence SARS-CoV-2 receptor TMPRSS2 expression among population cohorts from multiple continents

Irham LM, Chou WH, Calkins MJ, Adikusuma W, Hsieh SL, Chang WC.

Abstract:

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Efficient production of recombinant SARS-CoV-2 spike protein using the baculovirus-silkworm system

Fujita R, Hino M, Ebihara T, Nagasato T, Masuda A, Lee JM, Fujii T, Mon H, Kakino K, Nagai R, Tanaka M, Tonooka Y, Moriyama T, Kusakabe T.

Abstract:

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Proteasome activator PA28γ-dependent degradation of coronavirus disease (COVID-19) nucleocapsid protein

Zhang H, Tu J, Cao C, Yang T, Gao L.

Abstract:

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B cell clonal expansion and convergent antibody responses to SARS-CoV-2

Nielsen SCA, Yang F, Hoh RA, Jackson KJL, Roeltgen K, Lee JY, Rustagi A, Rogers AJ, Powell AE, Kim PS, Wang TT, Pinsky B, Blish CA, Boyd SD.

Abstract:

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Potentially repurposable drugs for COVID-19 identified from SARS-CoV-2 Host Protein Interactome

Karunakaran KB, Balakrishnan N, Ganapathiraju M.

Abstract:

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In silico Drug Repurposing to combat COVID-19 based on Pharmacogenomics of Patient Transcriptomic Data

Das S, Camphausen K, Shankavaram U.

Abstract:

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The COVID-19 Gene and Drug Set Library

Kuleshov MV, Clarke DJB, Kropiwnicki E, Jagodnik KM, Bartal A, Evangelista JE, Zhou A, Ferguson LB, Lachmann A, Ma'ayan A.

Abstract:

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SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyper-activation

Yan B, Freiwald T, Chauss D, Wang L, West E, Bibby J, Olson M, Kordasti S, Portilla D, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M.

Abstract:

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Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride

Xiao Q, Wang L, Supekar S, Shen T, Liu H, Ye F, Huang J, Fan H, Wei Z, Zhang C.

Abstract:

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Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis

Maremanda KP, Sundar IK, Li D, Rahman I.

Abstract:

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COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, Miorin L, Olmo EMD, Alon A, Delaforge E, Hennecker CD, Wang G, Pottel J, Bona R, Smith N, Hall JM, Shapiro G, Clark H, Mittermaier A, Kruse AC, García-Sastre A, Roth BL, Glasspool-Malone J, Francone V, Hertzog N, Fremont-Smith M, Ricke DO.

Abstract:

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Can Hyperperfusion of Nonaerated Lung Explain COVID-19 Hypoxia?

Herrmann J, Mori V, Bates JHT, Suki B.

Abstract:

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Interactome of SARS-CoV-2 / nCoV19 modulated host proteins with computationally predicted PPIs

Karunakaran KB, Balakrishnan N, Ganapathiraju MK.

Abstract:

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An in-silico approach to develop of a multi-epitope vaccine candidate against SARS-CoV-2 envelope (E) protein

Ghafouri F, Cohan RA, Noorbakhsh F, Samimi H, Haghpanah V.

Abstract:

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Intermolecular interaction among Remdesivir, RNA and RNA-dependent RNA polymerase of SARS-CoV-2 analyzed by fragment molecular orbital calculation

Kato K, Honma T, Fukuzawa K.

Abstract:

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Comparison of serologic and molecular SARS-CoV 2 results in a large cohort in Southern Tuscany demonstrates a role for serologic testing to increase diagnostic sensitivity

Pancrazzi A, Magliocca P, Lorubbio M, Vaggelli G, Galano A, Mafucci M, Duranti D, Cortesi M, Mazzeschi E, Fabbroni S, Viti G, Tartaglia Polcini A, Tripodo E, Sanchini P, Gervino S, Tacconi D, Dei S, Mazzierli M, D'Urso A, Ognibene A.

Abstract:

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Virological surveillance of SARS-CoV-2 in an Italian northern area: comparison of Real Time RT PCR cycle threshold (Ct) values in three epidemic periods

Veronesi L, Colucci ME, Pasquarella C, Caruso L, Mohieldin Mahgoub Ibrahim M, Zoni R, Pergreffi M, Arcuri C, Seidenari C, Viani I, Capobianco E, Mezzetta S, Affanni P.

Abstract:

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Emergence of European and North American mutant variants of SARS-CoV-2 in Southeast Asia

Islam OK, Al-Emran HM, Hasan MS, Anwar A, Jahid MIK, Hossain MA.

Abstract:

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Surveillance for Probable COVID-19 using Structured Data in the Electronic Medical Record

Burke PC, Shirley RB, Faiman M, Boose EW, Jones RW, Merlino A, Gordon SM, Fraser TG.

Abstract:

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Monoclonal antibodies for the S2 subunit of spike of SARS-CoV-1 cross-react with the newly-emerged SARS-CoV-2

Zheng Z, Monteil VM, Maurer-Stroh S, Yew CW, Leong C, Mohd-Ismail NK, Cheyyatraivendran Arularasu S, Chow VTK, Lin RTP, Mirazimi A, Hong W, Tan YJ.

Abstract:

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Clock genes may drive seasonal variation in SARS-CoV-2 infectivity: are we due for a second wave of COVID-19 in the fall?

Goren A, Wambier CG, McCoy J, Shapiro J, Vaño-Galván S, Herrera S, Glode LM.

Abstract:

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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris M, Wu NC, Nourmohammad A, Mok CKP.

Abstract:

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Cold sensitivity of the SARS-CoV-2 spike ectodomain

Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Gobeil SMC, Janowska K, Li D, Lu X, Deyton M, Sprenz J, Williams W, Saunders K, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P.

Abstract:

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Single-nucleotide conservation state annotation of SARS-CoV-2 genome

Kwon SB, Ernst J.

Abstract:

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Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

Wang B, Asarnow D, Lee WH, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Hu Y, Seah SGK, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI.

Abstract:

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Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies

Davies JP, Almasy KM, McDonald EF, Plate L.

Abstract:

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Prophylactic and Therapeutic Inhibition of In Vitro SARS-CoV-2 Replication by Oleandrin

Plante KS, Plante JA, Fernandez D, Mirchandani D, Bopp N, Aguilar PV, Sastry KJ, Newman RA, Weaver SC.

Abstract:

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Targeting heparan sulfate proteoglycan-assisted endocytosis as a COVID-19 therapeutic option

Zhang Q, Chen CZ, Swaroop M, Xu M, Wang L, Lee J, Pradhan M, Shen M, Luo Z, Xu Y, Huang W, Zheng W, Ye Y.

Abstract:

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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris JSM, Wu NC, Nourmohammad A, Mok CKP.

Abstract:

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Remote Virtual Spinal Evaluation in the Era of COVID-19

Yoon JW, Welch RL, Alamin T, Lavelle WF, Cheng I, Perez-Cruet M, Fielding LC, Sasso RC, Linovitz RJ, Kim KD, Welch WC.

Abstract:

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Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Cauchois R, Koubi M, Delarbre D, Manet C, Carvelli J, Blasco VB, Jean R, Fouche L, Bornet C, Pauly V, Mazodier K, Pestre V, Jarrot PA, Dinarello CA, Kaplanski G.

Abstract:

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Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures

Vanderheiden A, Ralfs P, Chirkova T, Upadhyay AA, Zimmerman MG, Bedoya S, Aoued H, Tharp GM, Pellegrini KL, Manfredi C, Sorscher E, Mainou B, Lobby JL, Kohlmeier JE, Lowen AC, Shi PY, Menachery VD, Anderson LJ, Grakoui A, Bosinger SE, Suthar MS.

Abstract:

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Mesenchymal stem cells: current clinical progress in ARDS and COVID-19

Xiao K, Hou F, Huang X, Li B, Qian ZR, Xie L.

Abstract:

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Targeting SARS-CoV-2 spike protein of COVID-19 with naturally occurring phytochemicals: an in silico study for drug development

Pandey P, Rane JS, Chatterjee A, Kumar A, Khan R, Prakash A, Ray S.

Abstract:

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Self-Amplifying RNA Viruses as RNA Vaccines

Lundstrom K.

Abstract:

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Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters

Osterrieder N, Bertzbach LD, Dietert K, Abdelgawad A, Vladimirova D, Kunec D, Hoffmann D, Beer M, Gruber AD, Trimpert J.

Abstract:

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Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear

Grubaugh ND, Hanage WP, Rasmussen AL.

Abstract:

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Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, Hengartner N, Giorgi EE, Bhattacharya T, Foley B, Hastie KM, Parker MD, Partridge DG, Evans CM, Freeman TM, de Silva TI; Sheffield COVID-19 Genomics Group, McDanal C, Perez LG, Tang H, Moon-Walker A, Whelan SP, LaBranche CC, Saphire EO, Montefiori DC.

Abstract:

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Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data

Chakraborti S, Bheemireddy S, Srinivasan N.

Abstract:

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Paper spray mass spectrometry utilizing Teslin® substrate for rapid detection of lipid metabolite changes during COVID-19 infection

De Silva IW, Nayek S, Singh V, Reddy J, Granger JK, Verbeck GF.

Abstract:

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[Discussion and prospect of infusion of NK cells in the treatment of SARS-CoV-2 infection]

Fan X, Wang S, Wu B, Cai C, Zhang J, Li Y, Meng Y.

Abstract:

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Antimalarial-agent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV-2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19

Sehailia M, Chemat S.

Abstract:

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Comparative molecular investigation of the potential inhibitors against SARS-CoV-2 main protease: a molecular docking study

Khan MA, Mahmud S, Alam ASMRU, Rahman ME, Ahmed F, Rahmatullah M.

Abstract:

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The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections

Machhi J, Herskovitz J, Senan AM, Dutta D, Nath B, Oleynikov MD, Blomberg WR, Meigs DD, Hasan M, Patel M, Kline P, Chang RC, Chang L, Gendelman HE, Kevadiya BD.

Abstract:

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Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies

Ragia G, Manolopoulos VG.

Abstract:

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Protective Immunity against SARS Subunit Vaccine Candidates Based on Spike Protein: Lessons for Coronavirus Vaccine Development

Khalaj-Hedayati A.

Abstract:

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GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune Response

Rudd CE.

Abstract:

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Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19

Carter-Timofte ME, J√∏rgensen SE, Freytag MR, Thomsen MM, Brinck Andersen NS, Al-Mousawi A, Hait AS, Mogensen TH.

Abstract:

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Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host

Ahmed SSSJ, Paramasivam P, Raj K, Kumar V, Murugesan R, Ramakrishnan V.

Abstract:

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Comments to: A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression

Parra-Medina R, Herrera S, Mejía J.

Abstract:

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The Two Sides of Cytopathology during the COVID-19 Health Emergency: Screening versus Diagnosis

Pisapia P, Troncone G.

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Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

Su YCF, Anderson DE, Young BE, Linster M, Zhu F, Jayakumar J, Zhuang Y, Kalimuddin S, Low JGH, Tan CW, Chia WN, Mak TM, Octavia S, Chavatte JM, Lee RTC, Pada S, Tan SY, Sun L, Yan GZ, Maurer-Stroh S, Mendenhall IH, Leo YS, Lye DC, Wang LF, Smith GJD.

Abstract:

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Current Trends and Future Approaches in Small-Molecule Therapeutics for COVID-19

Laws M, Surani YM, Hasan MM, Chen Y, Jin P, AlAdhami T, Chowdhury M, Imran A, Psaltis I, Jamshidi S, Nahar KS, Rahman KM.

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Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses

Nebigil CG, Moog C, Vagner S, Benkirane-Jessel N, Smith DR, Désaubry L.

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A molecular docking study revealed that synthetic peptides induced conformational changes in the structure of SARS-CoV-2 spike glycoprotein, disrupting the interaction with human ACE2 receptor

Souza PFN, Lopes FES, Amaral JL, Freitas CDT, Oliveira JTA.

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COVID-19 Docking Server: A meta server for docking small molecules, peptides and antibodies against potential targets of COVID-19

Kong R, Yang G, Xue R, Liu M, Wang F, Hu J, Guo X, Chang S.

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Multiplex reverse transcription loop-mediated isothermal amplification combined with nanoparticle-based lateral flow biosensor for the diagnosis of COVID-19

Zhu X, Wang X, Han L, Chen T, Wang L, Li H, Li S, He L, Fu X, Chen S, Xing M, Chen H, Wang Y.

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Speech-Language Pathology Management for Adults With COVID-19 in the Acute Hospital Setting: Initial Recommendations to Guide Clinical Practice

Namasivayam-MacDonald AM, Riquelme LF.

Abstract:

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Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

Schmidt F, Weisblum Y, Muecksch F, Hoffmann HH, Michailidis E, Lorenzi JCC, Mendoza P, Rutkowska M, Bednarski E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, Caskey M, Robbiani DF, Nussenzweig MC, Rice CM, Hatziioannou T, Bieniasz PD.

Abstract:

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Virtual screening, molecular dynamics and structure-activity relationship studies to identify potent approved drugs for Covid-19 treatment

Rahman MM, Saha T, Islam KJ, Suman RH, Biswas S, Rahat EU, Hossen MR, Islam R, Hossain MN, Mamun AA, Khan M, Ali MA, Halim MA.

Abstract:

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Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19

Chien M, Anderson TK, Jockusch S, Tao C, Li X, Kumar S, Russo JJ, Kirchdoerfer RN, Ju J.

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ACE2, TMPRSS2, and Furin variants and SARS-CoV-2 infection in Madrid, Spain

Torre-Fuentes L, Matías-Guiu J, Hernández-Lorenzo L, Montero-Escribano P, Pytel V, Porta-Etessam J, Gómez-Pinedo U, Matías-Guiu JA.

Abstract:

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Natural derivatives with dual binding potential against SARS-CoV-2 main protease and human ACE2 possess low oral bioavailability: a brief computational analysis

Sharma P, Shanavas A.

Abstract:

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Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells

Appelberg S, Gupta S, Akusjärvi SS, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, Krishnan S, Singh K, Penninger JM, Mirazimi A, Neogi U.

Abstract:

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Cyanobacterial metabolites as promising drug leads against the M(pro) and PL(pro) of SARS-CoV-2: an in silico analysis

Naidoo D, Roy A, Kar P, Mutanda T, Anandraj A.

Abstract:

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The antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds - Additional weapons in the fight against the COVID-19 pandemic?

Fuzimoto AD, Isidoro C.

Abstract:

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COVID-19 infection: mitohormetic concept of immune response

Gebicki J, Wieczorkowska M.

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An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Heydenburg Fuller D.

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Regarding pandemics: Ibn Jatima from Almería anticipates the physiopathological concept of multi-organ failure in the 14th century

Herrera Carranza M.

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Biological, clinical and epidemiological features of COVID-19, SARS and MERS and AutoDock simulation of ACE2

Zhang XY, Huang HJ, Zhuang DL, Nasser MI, Yang MH, Zhu P, Zhao MY.

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Immune Responses to the Novel Coronavirus-2: Friend or Foe?

Mahmoodpoor A, Nader ND.

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Neuropathogenic human coronaviruses: A review

Abdelaziz OS, Waffa Z.

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Structure-based virtual screening to discover potential lead molecules for the SARS-CoV-2 main protease

Gahlawat A, Kumar N, Kumar R, Sandhu H, Singh IP, Singh S, Sjöstedt A, Garg P.

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Distribution of SARS-CoV-2 PCR Cycle Threshold Values Provide Practical Insight Into Overall and Target-Specific Sensitivity Among Symptomatic Patients

Buchan BW, Hoff JS, Gmehlin CG, Perez A, Faron ML, Munoz-Price LS, Ledeboer NA.

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Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants

Fatoki TH, Ibraheem O, Ogunyemi IO, Akinmoladun AC, Ugboko HU, Adeseko CJ, Awofisayo OA, Olusegun SJ, Enibukun JM.

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SARS-CoV-2 encoded proteome and human genetics: from interaction-based to ribosomal biology impact on disease and risk processes

Sirpilla O, Bauss J, Gupta R, Underwood A, Qutob D, Freeland T, Bupp C, Carcillo J, Hartog N, Rajasekaran S, Prokop JW.

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Epigenetic mechanisms regulating COVID-19 infection

Chlamydas S, Papavassiliou AG, Piperi C.

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Novel coronavirus SARS-CoV-2 (Covid-19) dynamics inside the human body

Saha A, Saha B.

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FoldRec-C2C: protein fold recognition by combining cluster-to-cluster model and protein similarity network

Shao J, Yan K, Liu B.

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Identification of COVID-19 Infection-Related Human Genes Based on a Random Walk Model in a Virus-Human Protein Interaction Network

Zhang Y, Zeng T, Chen L, Ding S, Huang T, Cai YD.

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Identification of novel mutations in RNA-dependent RNA polymerases of SARS-CoV-2 and their implications on its protein structure

Chand GB, Banerjee A, Azad GK.

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The Future of Pathology: What can we Learn from the COVID-19 Pandemic?

Williams BJ, Fraggetta F, Hanna MG, Huang R, Lennerz J, Salgado R, Sirintrapun SJ, Pantanowitz L, Parwani A, Zarella M, Treanor DE.

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Comparison five primer sets from different genome region of COVID-19 for detection of virus infection by conventional RT-PCR

Mollaei HR, Afshar AA, Kalantar-Neyestanaki D, Fazlalipour M, Aflatoonian B.

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In-silico drug repurposing and molecular dynamics puzzled out potential SARS-CoV-2 main protease inhibitors

Ibrahim MAA, Abdelrahman AHM, Hegazy MF.

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Targeting virus-host interaction by novel pyrimidine derivative: an in silico approach towards discovery of potential drug against COVID-19

Rane JS, Pandey P, Chatterjee A, Khan R, Kumar A, Prakash A, Ray S.

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Dysfunction of adaptive immunity is related to severity of COVID-19: a retrospective study

Xie L, Wu Q, Lin Q, Liu X, Lin W, Hao S, Hu W, Xiang G, Lu H, Li S.

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Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Noorimotlagh Z, Karami C, Mirzaee SA, Kaffashian M, Mami S, Azizi M.

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Immuno-pathogenesis of nCOVID-19 and a possible host-directed therapy including anti-inflammatory and anti-viral prostaglandin (PG J(2)) for effective treatment and reduction in the death toll

Shahzad S, Willcox M.

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Virology, pathogenesis, diagnosis and in-line treatment of COVID-19

Samudrala PK, Kumar P, Choudhary K, Thakur N, Wadekar GS, Dayaramani R, Agrawal M, Alexander A.

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Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series

Bradley BT, Maioli H, Johnston R, Chaudhry I, Fink SL, Xu H, Najafian B, Deutsch G, Lacy JM, Williams T, Yarid N, Marshall DA.

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Blocking IL-1 to prevent respiratory failure in COVID-19

van de Veerdonk FL, Netea MG.

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Covid-19 infection and the host genetic predisposition: does it exist?

Vašků A.

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Design of a Multi-epitope Vaccine against SARS-CoV-2 using Immunoinformatics approach

Sanami S, Zandi M, Pourhossein B, Mobini GR, Safaei M, Abed A, Arvejeh PM, Chermahini FA, Alizadeh M.

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SARS-CoV-2 replicating in non-primate mammalian cells probably have critical advantages for COVID-19 vaccines due to anti-Gal antibodies: A minireview and proposals

Chen JM.

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ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

Benetti E, Tita R, Spiga O, Ciolfi A, Birolo G, Bruselles A, Doddato G, Giliberti A, Marconi C, Musacchia F, Pippucci T, Torella A, Trezza A, Valentino F, Baldassarri M, Brusco A, Asselta R, Bruttini M, Furini S, Seri M, Nigro V, Matullo G, Tartaglia M, Mari F; GEN-COVID Multicenter Study, Renieri A, Pinto AM.

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SARS-CoV-2 as a Factor to Disbalance the Renin-Angiotensin System: A Suspect in the Case of Exacerbated IL-6 Production

Franco R, Rivas-Santisteban R, Serrano-Marín J, Rodríguez-Pérez AI, Labandeira-García JL, Navarro G.

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SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection

Altmann DM, Boyton RJ.

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Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T, Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T, Cheng J, Straub JH, Stürzel CM, Fröhlich T, Berninghausen O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R.

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Modelling the inactivation of viruses from the Coronaviridae family in response to temperature and relative humidity in suspensions or surfaces

Guillier L, Martin-Latil S, Chaix E, Thébault A, Pavio N, Le Poder S, Batéjat C, Biot F, Koch L, Schaffner D, Sanaa M; Covid-19 Emergency Collective Expert Appraisal Group.

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Glucose-6-Phosphate Dehydrogenase Deficiency and COVID-19 Infection

Vick DJ.

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Comprehensive Review on Current Interventions, Diagnostic, and Nanotechnology Perspectives against SARS-CoV-2

Chauhan DS, Prasad R, Srivastava R, Jaggi M, Chauhan SC, Yallapu MM.

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SARS-CoV-2 Virologic and Immunologic Correlates in Patients with Olfactory and Taste Disorders

Benazzo M, Cassaniti I, Maiorano E, Calastri A, Novazzi F, Bonetti A, Sarasini A, Bruno R, Baldanti F.

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Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target

Enríquez-Flores S, Flores-López LA, García-Torres I, de la Mora-de la Mora I, Cabrera N, Gutiérrez-Castrellón P, Martínez-Pérez Y, López-Velázquez G.

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Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes

Zettl F, Meister TL, Vollmer T, Fischer B, Steinmann J, Krawczyk A, V'kovski P, Todt D, Steinmann E, Pfaender S, Zimmer G.

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Increased CD95 (Fas) and PD-1 expression in peripheral blood T lymphocytes in COVID-19 patients

Bellesi S, Metafuni E, Hohaus S, Maiolo E, Marchionni F, D'Innocenzo S, La Sorda M, Ferraironi M, Ramundo F, Fantoni M, Murri R, Cingolani A, Sica S, Gasbarrini A, Sanguinetti M, Chiusolo P, De Stefano V.

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Biotin Functionalized Self-Assembled Peptide Nanofiber as an Adjuvant for Immunomodulatory Response

Demircan MB, Tohumeken S, Gunduz N, Khalily MA, Tekinay T, Guler MO, Tekinay AB.

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The «moonlighting protein» able to explain the T(h)1 immune lockdown in severe COVID-19

Roncati L, Lusenti B.

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Application prospect of polysaccharides in the development of anti-novel coronavirus drugs and vaccines

Chen X, Han W, Wang G, Zhao X.

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Performance evaluation of Abbott ARCHITECT SARS-CoV-2 IgG immunoassay in comparison with indirect immunofluorescence and virus microneutralization test

Meschi S, Colavita F, Bordi L, Matusali G, Lapa D, Amendola A, Vairo F, Ippolito G, Capobianchi MR, Castilletti C; INMICovid-19 laboratory team.

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COVID-19: from rapid genome sequencing to fast decisions

Behrmann O, Spiegel M.

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Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

Meredith LW, Hamilton WL, Warne B, Houldcroft CJ, Hosmillo M, Jahun AS, Curran MD, Parmar S, Caller LG, Caddy SL, Khokhar FA, Yakovleva A, Hall G, Feltwell T, Forrest S, Sridhar S, Weekes MP, Baker S, Brown N, Moore E, Popay A, Roddick I, Reacher M, Gouliouris T, Peacock SJ, Dougan G, Török ME, Goodfellow I.

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Lower prevalence of antibodies neutralizing SARS-CoV-2 in group O French blood donors

Gallian P, Pastorino B, Morel P, Chiaroni J, Ninove L, de Lamballerie X.

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In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2

Pizzorno A, Padey B, Dubois J, Julien T, Traversier A, Dulière V, Brun P, Lina B, Rosa-Calatrava M, Terrier O.

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Drug repurposing studies targeting SARS-CoV-2: an ensemble docking approach on drug target 3C-like protease (3CL(pro))

Koulgi S, Jani V, Uppuladinne M, Sonavane U, Nath AK, Darbari H, Joshi R.

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The utility of native MS for understanding the mechanism of action of repurposed therapeutics in COVID-19: heparin as a disruptor of the SARS-CoV-2 interaction with its host cell receptor

Yang Y, Du Y, Kaltashov IA.

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Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

Oude Munnink BB, Nieuwenhuijse DF, Stein M, O'Toole Á, Haverkate M, Mollers M, Kamga SK, Schapendonk C, Pronk M, Lexmond P, van der Linden A, Bestebroer T, Chestakova I, Overmars RJ, van Nieuwkoop S, Molenkamp R, van der Eijk AA, GeurtsvanKessel C, Vennema H, Meijer A, Rambaut A, van Dissel J, Sikkema RS, Timen A, Koopmans M; Dutch-Covid-19 response team.

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Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

Ostaszewski M, Mazein A, Gillespie ME, Kuperstein I, Niarakis A, Hermjakob H, Pico AR, Willighagen EL, Evelo CT, Hasenauer J, Schreiber F, Dräger A, Demir E, Wolkenhauer O, Furlong LI, Barillot E, Dopazo J, Orta-Resendiz A, Messina F, Valencia A, Funahashi A, Kitano H, Auffray C, Balling R, Schneider R.

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Detection and Genetic Characterization of Community-Based SARS-CoV-2 Infections - New York City, March 2020

Bushman D, Alroy KA, Greene SK, Keating P, Wahnich A, Weiss D, Pathela P, Harrison C, Rakeman J, Langley G, Tong S, Tao Y, Uehara A, Queen K, Paden CR, Szymczak W, Orner EP, Nori P, Lai PA, Jacobson JL, Singh HK, Calfee DP, Westblade LF, Vasovic LV, Rand JH, Liu D, Singh V, Burns J, Prasad N; CDC COVID-19 Surge Laboratory Group;, Sell J.

Abstract:

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Designing a multi-epitope vaccine against SARS-CoV-2: an immunoinformatics approach

Samad A, Ahammad F, Nain Z, Alam R, Imon RR, Hasan M, Rahman MS.

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Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19

Dogan M, Kozhaya L, Placek L, Gunter C, Yigit M, Hardy R, Plassmeyer M, Coatney P, Lillard K, Bukhari Z, Kleinberg M, Hayes C, Arditi M, Klapper E, Merin N, Liang BT, Gupta R, Alpan O, Unutmaz D.

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Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators

Schwarz B, Sharma L, Roberts L, Peng X, Bermejo S, Leighton I, Massana AC, Farhadian S, Ko A, DelaCruz C, Bosio CM.

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Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex

Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng ET, Vatandaslar H, Chait B, Kapoor T, Darst SA, Campbell EA.

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Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

Rathnasinghe R, Strohmeier S, Amanat F, Gillespie VL, Krammer F, García-Sastre A, Coughlan L, Schotsaert M, Uccellini M.

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Conserved Genomic Terminals of SARS-CoV-2 as Co-evolving Functional Elements and Potential Therapeutic Targets

Chan AP, Choi Y, Schork NJ.

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SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function

Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, Holtzman MJ, Diamond MS.

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SARS-CoV-2 contributes to altering the post-transcriptional regulatory networks across human tissues by sponging RNA binding proteins and micro-RNAs

Srivastava R, Daulatabad SV, Srivastava M, Janga SC.

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Comprehensive in-vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

Huston NC, Wan H, Araujo Tavares RC, Wilen C, Pyle AM.

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Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis

Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Shrihari S, McCune BT, Harvey IB, Smith B, Keeler SP, Bloyet LM, Winkler ES, Holtzman MJ, Fremont DH, Whelan SPJ, Diamond MS.

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N and O glycosylation of the SARS-CoV-2 spike protein

Sanda M, Morrison L, Goldman R.

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Unique transcriptional changes in coagulation cascade genes in SARS-CoV-2-infected lung epithelial cells: A potential factor in COVID-19 coagulopathies

FitzGerald ES, Jamieson AM.

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Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2

Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Stevens B, Lee JY, Rustagi A, Rogers AJ, Powell AE, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Chang HY, Satpathy AT, Jardetzky TS, Kim PS, Wang TT, Pinsky BA, Blish CA, Boyd SD.

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Which animals are at risk? Predicting species susceptibility to Covid-19

Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS.

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Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3

Virdi RS, Bavisotto RV, Hopper NC, Frick DN.

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A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

Zhou Y, Hou Y, Shen J, Kallianpur A, Zein J, Culver DA, Farha S, Comhair S, Fiocchi C, Gack MU, Mehra R, Stappenbeck T, Chan T, Eng C, Jung JU, Jehi L, Erzurum S, Cheng F.

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Insights into Potential Mechanisms of Injury and Treatment Targets in COVID-19, SARS-Cov-2 Infection

Zhyvotovska A, Yusupov D, Foronjy R, Nakeshbandi M, McFarlane SI, Salifu M.

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GPU-Accelerated Drug Discovery with Docking on the Summit Supercomputer: Porting, Optimization, and Application to COVID-19 Research

LeGrand S, Scheinberg A, Tillack AF, Thavappiragasam M, Vermaas JV, Agarwal R, Larkin J, Poole D, Santos-Martins D, Solis-Vasquez L, Koch A, Forli S, Hernandez O, Smith JC, Sedova A.

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ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19

Bao R, Hernandez K, Huang L, Luke JJ.

Abstract:

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Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

Aguiar JA, Tremblay BJ, Mansfield MJ, Woody O, Lobb B, Banerjee A, Chandiramohan A, Tiessen N, Cao Q, Dvorkin-Gheva A, Revill S, Miller MS, Carlsten C, Organ L, Joseph C, John A, Hanson P, Austin R, McManus BM, Jenkins G, Mossman K, Ask K, Doxey AC, Hirota JA.

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Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

Kreer C, Zehner M, Weber T, Ercanoglu MS, Gieselmann L, Rohde C, Halwe S, Korenkov M, Schommers P, Vanshylla K, Di Cristanziano V, Janicki H, Brinker R, Ashurov A, Krähling V, Kupke A, Cohen-Dvashi H, Koch M, Eckert JM, Lederer S, Pfeifer N, Wolf T, Vehreschild MJGT, Wendtner C, Diskin R, Gruell H, Becker S, Klein F.

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Rapid Gel Card Agglutination Assays for Serological Analysis Following SARS-CoV-2 Infection in Humans

Alves D, Curvello R, Henderson E, Kesarwani V, Walker JA, Leguizamon SC, McLiesh H, Raghuwanshi VS, Samadian H, Wood EM, McQuilten ZK, Graham M, Wieringa M, Korman TM, Scott TF, Banaszak Holl MM, Garnier G, Corrie SR.

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Excess soluble fms-like tyrosine kinase 1 correlates with endothelial dysfunction and organ failure in critically ill COVID-19 patients

Dupont V, Kanagaratnam L, Goury A, Poitevin G, Bard M, Julien G, Bonnivard M, Champenois V, Noel V, Mourvillier B, Nguyen P.

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Computer-aided screening for potential TMPRSS2 inhibitors: a combination of pharmacophore modeling, molecular docking and molecular dynamics simulation approaches

Idris MO, Yekeen AA, Alakanse OS, Durojaye OA.

Abstract:

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Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics

VanPatten S, He M, Altiti A, F Cheng K, Ghanem MH, Al-Abed Y.

Abstract:

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Targeting zinc metalloenzymes in COVID-19

Doboszewska U, Wlaź P, Nowak G, Młyniec K.

Abstract:

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Induced Cardiovascular Syndrome: Etiology, Outcomes, and Management

Turshudzhyan A.

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Focusing On A Unique Innate Memory Cell Population Of Natural Killer Cells In The Fight Against COVID-19: Harnessing The Ubiquity Of Cytomegalovirus Exposure

Jaiswal SR, Malhotra P, Mitra DK, Chakrabarti S.

Abstract:

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Immune and Metabolic Signatures of COVID-19 Revealed by Transcriptomics Data Reuse

Gardinassi LG, Souza COS, Sales-Campos H, Fonseca SG.

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Severe COVID-19: NLRP3 Inflammasome Dysregulated

van den Berg DF, Te Velde AA.

Abstract:

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Battling COVID-19 Pandemic: Sphingosine-1-Phosphate Analogs as an Adjunctive Therapy?

Naz F, Arish M.

Abstract:

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MicroGMT: A Mutation Tracker for SARS-CoV-2 and Other Microbial Genome Sequences

Xing Y, Li X, Gao X, Dong Q.

Abstract:

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A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

Rambaut A, Holmes EC, O'Toole Á, Hill V, McCrone JT, Ruis C, du Plessis L, Pybus OG.

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Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

Mathew D, Giles JR, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Ramage H, Cherry S, Hensley SE, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit, Betts MR, Meyer NJ, Wherry EJ.

Abstract:

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Comprehensive mapping of immune perturbations associated with severe COVID-19

Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum RS, Mathew D, Baxter AE, Vella LA, Kuthuru O, Apostolidis SA, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR.

Abstract:

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Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs

Zhong LLD, Lam WC, Yang W, Chan KW, Sze SCW, Miao J, Yung KKL, Bian Z, Wong VT.

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COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks

Blaess M, Kaiser L, Sauer M, Csuk R, Deigner HP.

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High Throughput Virtual Screening to Discover Inhibitors of the Main Protease of the Coronavirus SARS-CoV-2

Olubiyi OO, Olagunju M, Keutmann M, Loschwitz J, Strodel B.

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Mutational Frequencies of SARS-CoV-2 Genome during the Beginning Months of the Outbreak in USA

Kaushal N, Gupta Y, Goyal M, Khaiboullina SF, Baranwal M, Verma SC.

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[Genetic and epigenetic variability, and the Covid-19 pandemic]

Rivera-Silva G.

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COVID-19: An Immunopathologic Assault

Munro N, Scordo KA, Richmond MM.

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SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

Le Bert N, Tan AT, Kunasegaran K, Tham CYL, Hafezi M, Chia A, Chng MHY, Lin M, Tan N, Linster M, Chia WN, Chen MI, Wang LF, Ooi EE, Kalimuddin S, Tambyah PA, Low JG, Tan YJ, Bertoletti A.

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Potently neutralizing and protective human antibodies against SARS-CoV-2

Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.

Abstract:

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A Molecular Docking Study Repurposes FDA Approved Iron Oxide Nanoparticles to Treat and Control COVID-19 Infection

Abo-Zeid Y, Ismail NS, McLean GR, Hamdy NM.

Abstract:

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Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection

Wan J, Xing S, Ding L, Wang Y, Gu C, Wu Y, Rong B, Li C, Wang S, Chen K, He C, Zhu D, Yuan S, Qiu C, Zhao C, Nie L, Gao Z, Jiao J, Zhang X, Wang X, Ying T, Wang H, Xie Y, Lu Y, Xu J, Lan F.

Abstract:

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Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease

Schultheiß C, Paschold L, Simnica D, Mohme M, Willscher E, von Wenserski L, Scholz R, Wieters I, Dahlke C, Tolosa E, Sedding DG, Ciesek S, Addo M, Binder M.

Abstract:

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SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters

Zhang AJ, Lee AC, Chu H, Chan JF, Fan Z, Li C, Liu F, Chen Y, Yuan S, Poon VK, Chan CC, Cai JP, Wu KL, Sridhar S, Chan YS, Yuen KY.

Abstract:

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Transcriptome-based drug repositioning for coronavirus disease 2019 (COVID-19)

Jia Z, Song X, Shi J, Wang W, He K.

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Trained innate immunity, COVID-19 therapeutic dilemma, and fake science

Beliz√°rio JE.

Abstract:

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Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies

Mishra SS, Ranjan S, Sharma CS, Singh HP, Kalra S, Kumar N.

Abstract:

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The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19

Bosso M, Thanaraj TA, Abu-Farha M, Alanbaei M, Abubaker J, Al-Mulla F.

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SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

Jiang HW, Li Y, Zhang HN, Wang W, Yang X, Qi H, Li H, Men D, Zhou J, Tao SC.

Abstract:

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Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

Sadegh S, Matschinske J, Blumenthal DB, Galindez G, Kacprowski T, List M, Nasirigerdeh R, Oubounyt M, Pichlmair A, Rose TD, Salgado-Albarrán M, Späth J, Stukalov A, Wenke NK, Yuan K, Pauling JK, Baumbach J.

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The spectrum of pathological findings in coronavirus disease (COVID-19) and the pathogenesis of SARS-CoV-2

Barth RF, Buja LM, Parwani AV.

Abstract:

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New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

Hou Y, Zhao J, Martin W, Kallianpur A, Chung MK, Jehi L, Sharifi N, Erzurum S, Eng C, Cheng F.

Abstract:

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Immunopathogenesis of COVID-19 and early immunomodulators

Lee KY, Rhim JW, Kang JH.

Abstract:

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Effects of Airborne Nanoparticles on the Nervous System: Amyloid Protein Aggregation, Neurodegeneration and Neurodegenerative Diseases

von Mikecz A, Schikowski T.

Abstract:

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Late histological findings in symptomatic COVID-19 patients: A case report

Aiolfi A, Bruni B, Biraghi T, Montisci A, Miceli A, Baronio B, Khor D, Cirri S, Donatelli F, Clemente C, Bona D.

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Reckoning a fungal metabolite, Pyranonigrin A as a potential Main protease (M(pro)) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation

Rao P, Shukla A, Parmar P, Rawal RM, Patel B, Saraf M, Goswami D.

Abstract:

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Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters

Liu Q, Zhao S, Shi CM, Song S, Zhu S, Su Y, Zhao W, Li M, Bao Y, Xue Y, Chen H.

Abstract:

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Single-cell RNA Expression Profiling of ACE2, The Receptor of SARS-CoV-2

Zhao Y, Zhao Z, Wang Y, Zhou Y, Ma Y, Zuo W.

Abstract:

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ACE2, the Receptor that Enables the Infection by SARS-CoV-2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators

Gross LZF, Sacerdoti M, Piiper A, Zeuzem S, Leroux AE, Biondi RM.

Abstract:

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Magnitude and kinetics of anti-SARS-CoV-2 antibody responses and their relationship to disease severity

Lynch KL, Whitman JD, Lacanienta NP, Beckerdite EW, Kastner SA, Shy BR, Goldgof GM, Levine AG, Bapat SP, Stramer SL, Esensten JH, Hightower AW, Bern C, Wu AHB.

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An immunotherapeutic method for COVID-19 patients: a soluble ACE2-Anti-CD16 VHH to block SARS-CoV-2 Spike protein

Sheikhi A, Hojjat-Farsangi M.

Abstract:

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Can the Environmental Phagocyte Acanthamoeba Be a Useful Model to Study SARS-CoV-2 Pathogenicity, Infectivity, and Evasion of Cellular Immune Defenses?

Siddiqui R, Khan NA.

Abstract:

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omputer modelling of a potential agent against SARS-Cov-2 (COVID-19) protease

Lesk AM, Konagurthu AS, Allison L, de la Banda MG, Stuckey PJ, Abramson D.

Abstract:

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Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses

Li R, Wu K, Li Y, Liang X, Lai KP, Chen J.

Abstract:

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Temporal Change of SARS-CoV-2 in Clinical Specimens of COVID-19 Pneumonia Patients

Luvira V, Jittmittraphap A, Muangnoicharoen S, Chantawat N, Janwitthayanan W, Leaungwutiwong P.

Abstract:

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Computational discovery of small drug-like compounds as potential inhibitors of SARS-CoV-2 main protease

Andrianov AM, Kornoushenko YV, Karpenko AD, Bosko IP, Tuzikov AV.

Abstract:

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Mesenchymal Stem Cell Derived Exosomes: a Nano Platform for Therapeutics and Drug Delivery in Combating COVID-19

Pinky, Gupta S, Krishnakumar V, Sharma Y, Dinda AK, Mohanty S.

Abstract:

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Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease

Qiao Z, Zhang H, Ji HF, Chen Q.

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Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development

Wan Q, Song D, Li H, He ML.

Abstract:

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Assessment of risk conferred by coding and regulatory variations of TMPRSS2 and CD26 in susceptibility to SARS-CoV-2 infection in human

Senapati S, Kumar S, Singh AK, Banerjee P, Bhagavatula S.

Abstract:

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The molecular virology of Coronaviruses

Hartenian E, Nandakumar D, Lari A, Ly M, Tucker JM, Glaunsinger BA.

Abstract:

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Broad and differential animal ACE2 receptor usage by SARS-CoV-2

Zhao X, Chen D, Szabla R, Zheng M, Li G, Du P, Zheng S, Li X, Song C, Li R, Guo JT, Junop M, Zeng H, Lin H.

Abstract:

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Forensic DNA testing during the SARS-CoV-2 pandemic

De Ungria MCA.

Abstract:

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The Challenge of Virtual Voice Therapy During the COVID-19 Pandemic

Cantarella G, Barillari MR, Lechien JR, Pignataro L.

Abstract:

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Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

Ni W, Yang X, Yang D, Bao J, Li R, Xiao Y, Hou C, Wang H, Liu J, Yang D, Xu Y, Cao Z, Gao Z.

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NPC1 as a Modulator of Disease Severity and Viral Entry of Sars-CoV-2

Vial C, Calderón JF, Klein AD.

Abstract:

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RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery

Zhu W, Chen CZ, Gorshkov K, Xu M, Lo DC, Zheng W.

Abstract:

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COVID-19, Renin-Angiotensin System and Endothelial Dysfunction

Amraei R, Rahimi N.

Abstract:

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A perspective on potential antibody-dependent enhancement of SARS-CoV-2

Arvin AM, Fink K, Schmid MA, Cathcart A, Spreafico R, Havenar-Daughton C, Lanzavecchia A, Corti D, Virgin HW.

Abstract:

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Evaluation of the Aptima™ transcription-mediated amplification assay (Hologic®) for detecting SARS-CoV-2 in clinical specimens

Trémeaux P, Lhomme S, Abravanel F, Raymond S, Mengelle C, Mansuy JM, Izopet J.

Abstract:

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First results of a national external quality assessment scheme for the detection of SARS-CoV-2 genome sequences

Görzer I, Buchta C, Chiba P, Benka B, Camp JV, Holzmann H, Puchhammer-Stöckl E, Aberle SW.

Abstract:

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Cytologic and molecular correlates of SARS-CoV-2 infection of the nasopharynx

Nuovo GJ, Magro C, Mikhail A.

Abstract:

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Long-term infection of SARS-CoV-2 changed the body's immune status

Lin L, Luo S, Qin R, Yang M, Wang X, Yang Q, Zhang Y, Wang Q, Zhu R, Fan H, Wang H, Hu Y, Wang L, Hu D.

Abstract:

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Genome-wide analysis of Indian SARS-CoV-2 genomes for the identification of genetic mutation and SNP

Saha I, Ghosh N, Maity D, Sharma N, Sarkar JP, Mitra K.

Abstract:

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Immunoglobulin fragment F(ab')(2) against RBD potently neutralizes SARS-CoV-2 in vitro

Pan X, Zhou P, Fan T, Wu Y, Zhang J, Shi X, Shang W, Fang L, Jiang X, Shi J, Sun Y, Zhao S, Gong R, Chen Z, Xiao G.

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[Are there genetic variants that can modify the course of the COVID-19 pandemic?]

Azurmendi PJ.

Abstract:

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Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans

Robson B.

Abstract:

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Michael Acceptors Tuned by the Pivotal Aromaticity of Histidine to Block COVID19 Activity

Poater A.

Abstract:

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The renin-angiotensin-aldosterone system: Role in pathogenesis and potential therapeutic target in COVID-19

Braga CL, Silva-Aguiar RP, Battaglini D, Peruchetti DB, Robba C, Pelosi P, Rocco PRM, Caruso-Neves C, Silva PL.

Abstract:

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The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity

Ovsyannikova IG, Haralambieva IH, Crooke SN, Poland GA, Kennedy RB.

Abstract:

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Severe acute respiratory syndrome coronavirus 2, original antigenic sin, and antibody-dependent enhancement: ménage à trois

Kadkhoda K.

Abstract:

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Proteomics and informatics for understanding phases and identifying biomarkers in COVID-19 disease

Whetton AD, Preston GW, Abubeker S, Geifman N.

Abstract:

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Types of Assays for SARS-CoV-2 Testing: A Review

Smithgall MC, Dowlatshahi M, Spitalnik SL, Hod EA, Rai AJ.

Abstract:

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SARS-CoV-2 will constantly sweep its tracks: a vaccine containing CpG motifs in 'lasso' for the multi-faced virus

Oberemok VV, Laikova KV, Yurchenko KA, Marochkin NA, Fomochkina II, Kubyshkin AV.

Abstract:

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Impact of Thiol-Disulfide Balance on the Binding of Covid-19 Spike Protein with Angiotensin-Converting Enzyme 2 Receptor

Hati S, Bhattacharyya S.

Abstract:

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Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARS-CoV-2 spike glycoprotein and its cellular receptor

Maurya VK, Kumar S, Prasad AK, Bhatt MLB, Saxena SK.

Abstract:

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Nanobodies: Prospects of Expanding the Gamut of Neutralizing Antibodies Against the Novel Coronavirus, SARS-CoV-2

Konwarh R.

Abstract:

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Targeting the NLRP3 Inflammasome in Severe COVID-19

Freeman TL, Swartz TH.

Abstract:

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Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies

Market M, Angka L, Martel AB, Bastin D, Olanubi O, Tennakoon G, Boucher DM, Ng J, Ardolino M, Auer RC.

Abstract:

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Biocides and Novel Antimicrobial Agents for the Mitigation of Coronaviruses

Dev Kumar G, Mishra A, Dunn L, Townsend A, Oguadinma IC, Bright KR, Gerba CP.

Abstract:

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Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein

Ye Q, West AMV, Silletti S, Corbett KD.

Abstract:

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SARS-CoV and SARS-CoV-2 main protease residue interaction networks change when bound to inhibitor N3

Griffin JWD.

Abstract:

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Computational insights into tetracyclines as inhibitors against SARS-CoV-2 M(pro) via combinatorial molecular simulation calculations

Bharadwaj S, Lee KE, Dwivedi VD, Kang SG.

Abstract:

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Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges

Hajivalili M, Hosseini M, Haji-Fatahaliha M.

Abstract:

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Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions

Kim SY, Jin W, Sood A, Montgomery DW, Grant OC, Fuster MM, Fu L, Dordick JS, Woods RJ, Zhang F, Linhardt RJ.

Abstract:

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In Silico Investigation of the SARS CoV2 Protease with Thymoquinone Major Constituent of Nigella Sativa

Kadil Y, Mouhcine M, Filali H.

Abstract:

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Comparative in silico design and validation of GPS‚Ñ¢ CoVID-19 dtec-RT-qPCR Test

Martínez-Murcia A, Bru G, Navarro A, Ros-Tárraga P, García-Sirera A, Pérez L.

Abstract:

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Coronavirus disease 2019 (COVID 19) and Malaria: Have anti glycoprotein antibodies a role?

Parodi A, Cozzani E.

Abstract:

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Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.

Abstract:

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Caution in Identifying Coronaviruses by Electron Microscopy

Goldsmith CS, Miller SE.

Abstract:

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A Case for Targeting Th17 Cells and IL-17A in SARS-CoV-2 Infections

Orlov M, Wander PL, Morrell ED, Mikacenic C, Wurfel MM.

Abstract:

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Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates

Ren W, Sun H, Gao GF, Chen J, Sun S, Zhao R, Gao G, Hu Y, Zhao G, Chen Y, Jin X, Fang F, Chen J, Wang Q, Gong S, Gao W, Sun Y, Su J, He A, Cheng X, Li M, Xia C, Li M, Sun L.

Abstract:

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Energetics and IC50 based epitope screening in SARS CoV-2 (COVID 19) spike protein by immunoinformatic analysis implicating for a suitable vaccine development

Banerjee A, Santra D, Maiti S.

Abstract:

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Natural transmission of bat-like SARS-CoV-2ÔÅÑPRRA variants in COVID-19 patients

Wong YC, Lau SY, Wang To KK, Mok BWY, Li X, Wang P, Deng S, Woo KF, Du Z, Li C, Zhou J, Woo Chan JF, Yuen KY, Chen H, Chen Z.

Abstract:

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Potential Immunotherapeutic Targets For Hypoxia Due to COVI-FLU

Leyfman Y, Erick TK, Reddy SS, Galwankar S, Nanayakkara PWB, Di Somma S, Sharma P, Stawicki SP, Chaudry IH.

Abstract:

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Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review

Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC.

Abstract:

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Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection

Keam S, Megawati D, Patel SK, Tiwari R, Dhama K, Harapan H.

Abstract:

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COVID-19: Phylogenetic approaches may help in finding resources for natural cure

Zaman W, Saqib S, Ullah F, Ayaz A, Ye J.

Abstract:

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Deploying Biomolecules as Anti-COVID-19 Agents

Patel SKS, Lee JK, Kalia VC.

Abstract:

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Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling

Rockett RJ, Arnott A, Lam C, Sadsad R, Timms V, Gray KA, Eden JS, Chang S, Gall M, Draper J, Sim EM, Bachmann NL, Carter I, Basile K, Byun R, O'Sullivan MV, Chen SC, Maddocks S, Sorrell TC, Dwyer DE, Holmes EC, Kok J, Prokopenko M, Sintchenko V.

Abstract:

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Detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissue sections using commercially available reagents

Best Rocha A, Stroberg E, Barton LM, Duval EJ, Mukhopadhyay S, Yarid N, Caza T, Wilson JD, Kenan DJ, Kuperman M, Sharma SG, Larsen CP.

Abstract:

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Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

McKay PF, Hu K, Blakney AK, Samnuan K, Brown JC, Penn R, Zhou J, Bouton CR, Rogers P, Polra K, Lin PJC, Barbosa C, Tam YK, Barclay WS, Shattock RJ.

Abstract:

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Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Early Manifestations of COVID-19 in Israel

Cohen-Gihon I, Israeli O, Shifman O, Stein D, Achdout H, Weiss S, Mandelboim M, Erster O, Regev-Yochay G, Segal G, Yitzhaki S, Shapira SC, Beth-Din A, Zvi A.

Abstract:

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Coding-Complete Genome Sequence of SARS-CoV-2 Isolate from Bangladesh by Sanger Sequencing

Moniruzzaman M, Hossain MU, Islam MN, Rahman MH, Ahmed I, Rahman TA, Bhattacharjee A, Amin MR, Rashed A, Keya CA, Das KC, Salimullah M.

Abstract:

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Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response

Vishnubalaji R, Shaath H, Alajez NM.

Abstract:

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Comparative genomic signature representations of the emerging COVID-19 coronavirus and other coronaviruses: High identity and possible recombination between Bat and Pangolin coronaviruses

Touati R, Haddad-Boubaker S, Ferchichi I, Messaoudi I, Ouesleti AE, Triki H, Lachiri Z, Kharrat M.

Abstract:

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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies

Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR, Koranda N, Gristick HB, Gaebler C, Muecksch F, Lorenzi JCC, Finkin S, Hägglöf T, Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey M, Robbiani DF, Nussenzweig MC, Bjorkman PJ.

Abstract:

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The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu

Abstract:

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Erythropoietin Induced Hemoglobin Sub-Unit Beta may Stimulate Innate Immune RNA Virus Pattern Recognition, Suppress Reactive Oxygen Species, Reduce ACE2 Viral Doorway Opening and Neutrophil Extracellular Traps against Covid-19

Brenner SR.

Abstract:

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Tackling COVID-19 infection through complement-targeted immunotherapy

Jodele S, Köhl J.

Abstract:

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On the potential role of exosomes in the COVID-19 reinfection/reactivation opportunity

Elrashdy F, Aljaddawi AA, Redwan EM, Uversky VN.

Abstract:

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Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor

Tripathi MK, Singh P, Sharma S, Singh TP, Ethayathulla AS, Kaur P.

Abstract:

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Potential of NO donor furoxan as SARS-CoV-2 main protease (M(pro)) inhibitors: in silico analysis

Al-Sehemi AG, Pannipara M, Parulekar RS, Patil O, Choudhari PB, Bhatia MS, Zubaidha PK, Tamboli Y.

Abstract:

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Natural-like products as potential SARS-CoV-2 M(pro) inhibitors: in-silico drug discovery

Ibrahim MAA, Abdeljawaad KAA, Abdelrahman AHM, Hegazy MF.

Abstract:

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Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19

Tao Q, Du J, Li X, Zeng J, Tan B, Xu J, Lin W, Chen XL.

Abstract:

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Ion channel inhibition against COVID-19: A novel target for clinical investigation

Navarese EP, Musci RL, Frediani L, Gurbel PA, Kubica J.

Abstract:

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Proteome-wide Data Analysis Reveals Tissue-specific Network Associated with SARS-CoV-2 Infection

Feng L, Yin YY, Liu CH, Xu KR, Li QR, Wu JR, Zeng R.

Abstract:

Link to Article

Do COVID-19 and SARS Gene Complexities and Variations Help Overcome the Knowledge Gap?

Javed M, Javed F, Ergin HE, Maung TZ, Khan S.

Abstract:

Link to Article

Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library

Dawadi S, Simmons N, Miklossy G, Bohren KM, Faver JC, Ucisik MN, Nyshadham P, Yu Z, Matzuk MM.

Abstract:

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Genomic Analysis of Early SARS-CoV-2 Variants Introduced in Mexico

Taboada B, Vazquez-Perez JA, Muñoz Medina JE, Ramos Cervantes P, Escalera-Zamudio M, Boukadida C, Sanchez-Flores A, Isa P, Mendieta Condado E, Martínez-Orozco JA, Becerril-Vargas E, Salas-Hernández J, Grande R, González-Torres C, Gaytán-Cervantes FJ, Vazquez G, Pulido F, Araiza Rodríguez A, Garcés Ayala F, González Bonilla CR, Grajales Muñiz C, Borja Aburto VH, Barrera Badillo G, López S, Hernández Rivas L, Perez-Padilla R, López Martínez I, Ávila-Ríos S, Ruiz-Palacios G, Ramírez

Abstract:

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Human genetics and genomics meetings going virtual: practical lessons learned from two international meetings in early 2020

Forrest ARR, Repetto GM, Reichardt JKV.

Abstract:

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Molecular Aspects of COVID-19 Differential Pathogenesis

Rothan HA, Acharya A, Reid SP, Kumar M, Byrareddy SN.

Abstract:

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BTK/ITK dual inhibitors: Modulating immunopathology and lymphopenia for COVID-19 therapy

McGee MC, August A, Huang W.

Abstract:

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Identification of potential inhibitors against SARS-CoV-2 by targeting proteins responsible for envelope formation and virion assembly using docking based virtual screening, and pharmacokinetics approaches

Bhowmik D, Nandi R, Jagadeesan R, Kumar N, Prakash A, Kumar D.

Abstract:

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Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease

Margină D, Ungurianu A, Purdel C, Nitulescu GM, Tsoukalas D, Sarandi E, Thanasoula M, Burykina TI, Tekos F, Buha A, Nikitovic D, Kouretas D, Tsatsakis AM.

Abstract:

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SARS-CoV2 envelope protein: Non-synonymous mutations and its consequences

Hassan SS, Choudhury PP, Roy B.

Abstract:

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COVID-19 and the Chemical Senses: Supporting Players Take Center Stage

Cooper KW, Brann DH, Farruggia MC, Bhutani S, Pellegrino R, Tsukahara T, Weinreb C, Joseph PV, Larson ED, Parma V, Albers MW, Barlow LA, Datta SR, Di Pizio A.

Abstract:

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Poly(ADP-ribose) Polymerase Inhibition in Acute Lung Injury: A Re-emerging Concept

Szabo C, Martins V, Liaudet L.

Abstract:

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Response of anti-SARS-CoV-2 total antibodies to nucleocapsid antigen in COVID-19 patients: a longitudinal study

Favresse J, Eucher C, Elsen M, Laffineur K, Dogné JM, Douxfils J.

Abstract:

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The early antibody response to SARS-Cov-2 infection

Dittadi R, Afshar H, Carraro P.

Abstract:

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DISEQUILIBRIUM BETWEEN THE CLASSIC RENIN-ANGIOTENSIN SYSTEM AND ITS OPPOSING ARM IN SARS-COV-2 RELATED LUNG INJURY

Sarzani R, Giulietti F, Di Pentima C, Giordano P, Spannella F.

Abstract:

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Systematic profiling of ACE2 expression in diverse physiological and pathological conditions for COVID-19/SARS-CoV-2

Li Y, Xu Q, Ma L, Wu D, Gao J, Chen G, Li H.

Abstract:

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Proteinase-activated receptor 1 (PAR1): A target for repurposing in the treatment of COVID-19?

Sriram K, Insel PA.

Abstract:

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Research progress on repositioning drugs and specific therapeutic drugs for SARS-CoV-2

Fan S, Xiao D, Wang Y, Liu L, Zhou X, Zhong W.

Abstract:

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Single-cell analysis of SARS-CoV-2 receptor ACE2 and spike protein priming expression of proteases in the human heart

Liu H, Gai S, Wang X, Zeng J, Sun C, Zhao Y, Zheng Z.

Abstract:

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Evidence for structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients

Thomas T, Stefanoni D, Dzieciatkowska M, Issaian A, Nemkov T, Hill RC, Francis RO, Hudson KE, Buehler PW, Zimring JC, Hod EA, Hansen KC, Spitalnik SL, D'Alessandro A.

Abstract:

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The Sensitivity of Respiratory Tract Specimens for the Detection of SARS-CoV-2: A Protocol for a Living Systematic Review and Meta-Analysis

Moore AJ, Nakahata MI, Kalinich CC, Nyhan K, Bromberg DJ, Shi X, Ko AI, Grubaugh ND, Casanovas-Massana A, Wyllie AL.

Abstract:

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Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells

Kwon Y, Nukala SB, Srivastava S, Miyamoto H, Ismail NI, Rehman J, Ong SB, Lee WH, Ong SG.

Abstract:

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SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN.

Abstract:

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Using iCn3D and the World Wide Web for structure-based collaborative research: Analyzing molecular interactions at the root of COVID-19

Youkharibache P, Cachau R, Madej T, Wang J.

Abstract:

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A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Alimova M, Sidhom EH, Satyam A, Dvela-Levitt M, Melanson M, Chamberlain BT, Alper SL, Santos J, Gutierrez J, Subramanian A, Grinkevich E, Bricio ER, Kim C, Clark A, Watts A, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A.

Abstract:

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Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

Bobrowski T, Chen L, Eastman RT, Itkin Z, Shinn P, Chen C, Guo H, Zheng W, Michael S, Simeonov A, Hall MD, Zakharov AV, Muratov EN.

Abstract:

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Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission

Sapoval N, Mahmoud M, Jochum MD, Liu Y, Leo Elworth RA, Wang Q, Albin D, Ogilvie H, Lee MD, Villapol S, Hernandez KM, Berry IM, Foox J, Beheshti A, Ternus K, Aagaard KM, Posada D, Mason CE, Sedlazeck F, Treangen TJ.

Abstract:

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A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies

Acharya P, Williams W, Henderson R, Janowska K, Manne K, Parks R, Deyton M, Sprenz J, Stalls V, Kopp M, Mansouri K, Edwards RJ, Meyerhoff RR, Oguin T, Sempowski G, Saunders K, Haynes BF.

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Assessment of Proton-Coupled Conformational Dynamics of SARS and MERS Coronavirus Papain-like Proteases: Implication for Designing Broad-Spectrum Antiviral Inhibitors

Henderson JA, Verma N, Shen J.

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Snapshot of the evolution and mutation patterns of SARS-CoV-2

Zhao J, Zhai X, Zhou J.

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Genetic architecture of host proteins interacting with SARS-CoV-2

Pietzner M, Wheeler E, Carrasco-Zanini J, Raffler J, Kerrison ND, Oerton E, Auyeung VPW, Luan J, Finan C, Casas JP, Ostroff R, Williams SA, Kastenmüller G, Ralser M, Gamazon ER, Wareham NJ, Hingorani AD, Langenberg C.

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High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity

Lu J, Sun PD.

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SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery

Mulay A, Konda B, Garcia G, Yao C, Beil S, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, Sainz de Aja J, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR.

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6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities

Swaim CD, Perng YC, Zhao X, Canadeo LA, Harastani HH, Darling TL, Boon ACM, Lenschow DJ, Huibregtse JM.

Abstract:

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SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain

Yurkovetskiy L, Pascal KE, Tompkins-Tinch C, Nyalile T, Wang Y, Baum A, Diehl WE, Dauphin A, Carbone C, Veinotte K, Egri SB, Schaffner SF, Lemieux JE, Munro J, Sabeti PC, Kyratsous C, Shen K, Luban J.

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Pathology and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Afewerky HK.

Abstract:

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Canonical and Noncanonical Autophagy as Potential Targets for COVID-19

Bello-Perez M, Sola I, Novoa B, Klionsky DJ, Falco A.

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ACE2 as a Therapeutic Target for COVID-19; its Role in Infectious Processes and Regulation by Modulators of the RAAS System

Michaud V, Deodhar M, Arwood M, Al Rihani SB, Dow P, Turgeon J.

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Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design

Wang D, Mai J, Zhou W, Yu W, Zhan Y, Wang N, Epstein ND, Yang Y.

Abstract:

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Kinetics of viral load and antibody response in relation to COVID-19 severity

Wang Y, Zhang L, Sang L, Ye F, Ruan S, Zhong B, Song T, Alshukairi AN, Chen R, Zhang Z, Gan M, Zhu A, Huang Y, Luo L, Mok CK, Al Gethamy MM, Tan H, Li Z, Huang X, Li F, Sun J, Zhang Y, Wen L, Li Y, Chen Z, Zhuang Z, Zhuo J, Chen C, Kuang L, Wang J, Lv H, Jiang Y, Li M, Lin Y, Deng Y, Tang L, Liang J, Huang J, Perlman S, Zhong N, Zhao J, Malik Peiris JS, Li Y, Zhao J.

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SARS-CoV-2 viral load and antibody responses: the case for convalescent plasma therapy

Casadevall A, Joyner MJ, Pirofski LA.

Abstract:

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Serum KL-6 can distinguish between different phenotypes of severe COVID-19

Nakamura H, Miyagi K, Otsuki M, Higure Y, Nishiyama N, Kinjo T, Nakamatsu M, Haranaga S, Tateyama M, Fujita J.

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The variability of the serological response to SARS corona virus-2: Potential resolution of ambiguity through determination of avidity (functional affinity)

Bauer G.

Abstract:

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RNA-dependent RNA Polymerase of SARS-CoV-2 as a Therapeutic Target

Wang Y, Anirudhan V, Du R, Cui Q, Rong L.

Abstract:

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An update on origin of SARS-CoV-2: Despite closest identity, bat (RaTG13) and Pangolin derived Coronaviruses varied in the critical binding site and O-linked glycan residues

Malaiyan J, Arumugam S, Mohan K, Radhakrishnan GG.

Abstract:

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The hemagglutinin-esterase gene in human coronaviruses SARS-CoV-2, HKU1 and OC43

Soltani S.

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Revisiting potential druggable targets against SARS-CoV-2 and repurposing therapeutics under preclinical study and clinical trials: A comprehensive review

Sohag AAM, Hannan MA, Rahman S, Hossain M, Hasan M, Khan MK, Khatun A, Dash R, Uddin MJ.

Abstract:

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In Silico Screening of Potential Chinese Herbal Medicine Against COVID-19 by Targeting SARS-CoV-2 3CLpro and Angiotensin Converting Enzyme II Using Molecular Docking

Gao LQ, Xu J, Chen SD.

Abstract:

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Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

De Biasi S, Meschiari M, Gibellini L, Bellinazzi C, Borella R, Fidanza L, Gozzi L, Iannone A, Lo Tartaro D, Mattioli M, Paolini A, Menozzi M, Milić J, Franceschi G, Fantini R, Tonelli R, Sita M, Sarti M, Trenti T, Brugioni L, Cicchetti L, Facchinetti F, Pietrangelo A, Clini E, Girardis M, Guaraldi G, Mussini C, Cossarizza A.

Abstract:

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Development and Evaluation of a duo SARS-CoV-2 RT-qPCR Assay Combining Two Assays Approved by the World Health Organization Targeting the Envelope and the RNA-Dependant RNA Polymerase (RdRp) Coding Regions

Pezzi L, Charrel RN, Ninove L, Nougairede A, Molle G, Coutard B, Durand G, Leparc-Goffart I, de Lamballerie X, Thirion L.

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Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

Palmeira A, Sousa E, Köseler A, Sabirli R, Gören T, Türkçüer İ, Kurt Ö, Pinto MM, Vasconcelos MH.

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Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits

Chu AW, Chan WM, Ip JD, Yip CC, Chan JF, Yuen KY, To KK.

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An overview of the genetic variations of the SARS-CoV-2 genomes isolated in Southeast Asian countries

Yap PSX, Tan TS, Chan YF, Tee KK, Kamarulzaman A, Teh CSJ.

Abstract:

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Considerations around the SARS-CoV-2 Spike Protein with particular attention to COVID-19 brain infection and neurological symptoms

Hassanzadeh K, Perez Pena H, Dragotto J, Buccarello L, Iorio F, Pieraccini S, Sancini G, Feligioni M.

Abstract:

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Dysregulation of the immune system as a driver of the critical course of the novel coronavirus disease 2019

Kosmaczewska A, Frydecka I.

Abstract:

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Role of the Backbenchers of the Renin-Angiotensin System ACE2 and AT2 Receptors in COVID-19: Lessons From SARS

Gumashta J, Gumashta R.

Abstract:

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Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses?

Ansari Ramandi MM, Baay M, Naderi N.

Abstract:

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SARS-CoV-2 host diversity: An update of natural infections and experimental evidence

Hossain MG, Javed A, Akter S, Saha S.

Abstract:

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Molecular mechanisms and epidemiology of COVID-19 from an allergist's perspective

Hosoki K, Chakraborty A, Sur S.

Abstract:

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Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies

Mercurio I, Tragni V, Busto F, De Grassi A, Pierri CL.

Abstract:

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Multiplex detection and dynamics of IgG antibodies to SARS-CoV2 and the highly pathogenic human coronaviruses SARS-CoV and MERS-CoV

Ayouba A, Thaurignac G, Morquin D, Tuaillon E, Raulino R, Nkuba A, Lacroix A, Vidal N, Foulongne V, Le Moing V, Reynes J, Delaporte E, Peeters M.

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Nucleic Acid Approaches to Antibody-based Therapeutics for COVID-19: A Perspective

Parzych E, Weiner DB.

Abstract:

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Mesenchymal stromal cells and their secreted extracellular vesicles as therapeutic tools for COVID-19 pneumonia? (*)

Muraca M, Pessina A, Pozzobon M, Dominici M, Galderisi U, Lazzari L, Parolini O, Lucarelli E, Perilongo G, Baraldi E.

Abstract:

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Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient

Yin S, Tong X, Huang A, Shen H, Li Y, Liu Y, Wu C, Huang R, Chen Y.

Abstract:

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Neurobiology of coronaviruses: Potential relevance for COVID-19

Cataldi M, Pignataro G, Taglialatela M.

Abstract:

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Ancestral origin, antigenic resemblance and epidemiological insights of novel coronavirus (SARS-CoV-2): Global burden and Bangladesh perspective

Uddin MB, Hasan M, Harun-Al-Rashid A, Ahsan MI, Imran MAS, Ahmed SSU.

Abstract:

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Integrated Approaches to Reveal Mechanisms by which RNA Viruses Reprogram the Cellular Environment

Haddad C, Davila-Calderon J, Tolbert BS.

Abstract:

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Open Synthesis and the coronavirus (COVID-19) pandemic in 2020

Haddaway NR, Akl EA, Page MJ, Welch VA, Keenan C, Lotfi T.

Abstract:

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Shape-based Machine Learning Models for the potential Novel COVID-19 protease inhibitors assisted by Molecular Dynamics Simulation

Khandelwal R, Nayarisseri A, Madhavi M, Selvaraj C, Panwar U, Sharma K, Hussain T, Singh SK.

Abstract:

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SARS-CoV-2 surveillance for a non-human primate breeding research facility

Yee JL, Van Rompay KKA, Carpenter AB, Nham PB, Halley BM, Iyer SS, Hartigan-O'Connor DJ, Miller CJ, Roberts JA.

Abstract:

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Digital pathology and artificial intelligence will be key to supporting clinical and academic cellular pathology through COVID-19 and future crises: the PathLAKE consortium perspective

Browning L, Colling R, Rakha E, Rajpoot N, Rittscher J, James JA, Salto-Tellez M, Snead DRJ, Verrill C.

Abstract:

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S2 Subunit of SARS-nCoV-2 Interacts with Tumor Suppressor Protein p53 and BRCA: an In Silico Study

Singh N, Bharara Singh A.

Abstract:

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Virtual screening based on molecular docking of possible inhibitors of Covid-19 main protease

Marinho EM, Batista de Andrade Neto J, Silva J, Rocha da Silva C, Cavalcanti BC, Marinho ES, Nobre J√∫nior HV.

Abstract:

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Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection

Messner CB, Demichev V, Wendisch D, Michalick L, White M, Freiwald A, Textoris-Taube K, Vernardis SI, Egger AS, Kreidl M, Ludwig D, Kilian C, Agostini F, Zelezniak A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, von Kalle C, Campbell A, Hayward C, Porteous DJ, Marioni RE, Langenberg C, Lilley KS, Kuebler WM, Mülleder M, Drosten C, Suttorp N, Witzenrath M, Kurth F, Sander LE, Ralser M.

Abstract:

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Shotgun proteomics analysis of SARS-CoV-2-infected cells and how it can optimize whole viral particle antigen production for vaccines

Grenga L, Gallais F, Pible O, Gaillard JC, Gouveia D, Batina H, Bazaline N, Ruat S, Culotta K, Miotello G, Debroas S, Roncato MA, Steinmetz G, Foissard C, Desplan A, Alpha-Bazin B, Almunia C, Gas F, Bellanger L, Armengaud J.

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Epitope based peptide vaccine against SARS-COV2: an immune-informatics approach

Bhatnager R, Bhasin M, Arora J, Dang AS.

Abstract:

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Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques

Deng W, Bao L, Liu J, Xiao C, Liu J, Xue J, Lv Q, Qi F, Gao H, Yu P, Xu Y, Qu Y, Li F, Xiang Z, Yu H, Gong S, Liu M, Wang G, Wang S, Song Z, Liu Y, Zhao W, Han Y, Zhao L, Liu X, Wei Q, Qin C.

Abstract:

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Complete Genome Sequence of a 2019 Novel Coronavirus (SARS-CoV-2) Strain Causing a COVID-19 Case in Morocco

Lemriss S, Souiri A, Amar N, Lemzaoui N, Mestoui O, Labioui M, Ouaariba N, Jibjibe A, Yartaoui M, Chahmi M, El Rhouila M, Sellak S, Kandoussi N, El Kabbaj S.

Abstract:

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Genome Sequencing of a Severe Acute Respiratory Syndrome Coronavirus 2 Isolate Obtained from a South African Patient with Coronavirus Disease 2019

Allam M, Ismail A, Khumalo ZTH, Kwenda S, van Heusden P, Cloete R, Wibmer CK, Mtshali PS, Mnyameni F, Mohale T, Subramoney K, Walaza S, Ngubane W, Govender N, Motaze NV, Bhiman JN; SA-COVID-19 response team.

Abstract:

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COVID-19 phenotypes: leading or misleading?

Gattinoni L, Camporota L, Marini JJ.

Abstract:

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Mesenchymal stem cells in the fight against viruses: Face to face with the invisible enemy

Sleem A, Saleh F.

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Is povidone-iodine mouthwash effective against SARS-CoV-2? First in vivo tests

Martínez Lamas L, Diz Dios P, Pérez Rodríguez MT, Del Campo P, Cabrera Alvargonzalez JJ, López Domínguez AM, Fernandez Feijoo J, Diniz Freitas M, Limeres Posse J.

Abstract:

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Characterizations of SARS-CoV-2 mutational profile, spike protein stability and viral transmission

Laha S, Chakraborty J, Das S, Manna SK, Biswas S, Chatterjee R.

Abstract:

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Rapid review methods more challenging during COVID-19: Commentary with a focus on 8 knowledge synthesis steps

Tricco AC, Garritty CM, Boulos L, Lockwood C, Wilson M, McGowan J, McCaul M, Hutton B, Clement F, Mittmann N, Devane D, Langlois EV, Abou-Setta AM, Houghton C, Glenton C, Kelly SE, Welch VA, LeBlanc A, Wells GA, Pham B, Lewin S, Straus SE.

Abstract:

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Main Routes of Entry and Genomic Diversity of SARS-CoV-2, Uganda

Bugembe DL, Kayiwa J, Phan MVT, Tushabe P, Balinandi S, Dhaala B, Lexow J, Mwebesa H, Aceng J, Kyobe H, Ssemwanga D, Lutwama J, Kaleebu P, Cotten M.

Abstract:

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SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines

Barr IG, Rynehart C, Whitney P, Druce J.

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COVID-19 Is Further Subdivided Into COVIP-19 and COVII-19

Song S.

Abstract:

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COVID-19 Is Distinct From SARS-CoV-2-Negative Community-Acquired Pneumonia

Zhou Y, Guo S, He Y, Zuo Q, Liu D, Xiao M, Fan J, Li X.

Abstract:

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Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients

Zhang BZ, Hu YF, Chen LL, Yau T, Tong YG, Hu JC, Cai JP, Chan KH, Dou Y, Deng J, Wang XL, Hung IF, To KK, Yuen KY, Huang JD.

Abstract:

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Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19

Demaria O, Carvelli J, Batista L, Thibult ML, Morel A, André P, Morel Y, Vély F, Vivier E.

Abstract:

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Angiotensin-converting enzyme 2, a SARS-CoV-2 receptor, is upregulated by interleukin-6 via STAT3 signaling in synovial tissues

Mokuda S, Tokunaga T, Masumoto J, Sugiyama E.

Abstract:

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COVID-19: Role of neutrophil extracellular traps in acute lung injury

Yaqinuddin A, Kvietys P, Kashir J.

Abstract:

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Molecular Alterations Prompted by SARS-CoV-2 Infection: Induction of Hyaluronan, Glycosaminoglycan and Mucopolysaccharide Metabolism

Andonegui-Elguera S, Taniguchi-Ponciano K, Gonzalez-Bonilla CR, Torres J, Mayani H, Herrera LA, Peña-Martínez E, Silva-Román G, Vela-Patiño S, Ferreira-Hermosillo A, Ramirez-Renteria C, Carvente-Garcia R, Mata-Lozano C, Marrero-Rodríguez D, Mercado M.

Abstract:

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Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

Drew ED, Janes RW.

Abstract:

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Topological analysis of SARS CoV-2 main protease

Estrada E.

Abstract:

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Does SARS-CoV-2 Trigger Stress-InducedAutoimmunity by Molecular Mimicry? A Hypothesis

Cappello F, Gammazza AM, Dieli F, de Macario, Macario AJ.

Abstract:

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Magneto-Optical Nanostructures for Viral Sensing

Szunerits S, Nait Saada T, Meziane D, Boukherroub R.

Abstract:

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Microbial Natural Products as Potential Inhibitors of SARS-CoV-2 Main Protease (M(pro))

Sayed AM, Alhadrami HA, El-Gendy AO, Shamikh YI, Belbahri L, Hassan HM, Abdelmohsen UR, Rateb ME.

Abstract:

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Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis

Song JW, Lam SM, Fan X, Cao WJ, Wang SY, Tian H, Chua GH, Zhang C, Meng FP, Xu Z, Fu JL, Huang L, Xia P, Yang T, Zhang S, Li B, Jiang TJ, Wang R, Wang Z, Shi M, Zhang JY, Wang FS, Shui G.

Abstract:

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Rapid, Sensitive, Full-Genome Sequencing of Severe Acute Respiratory Syndrome Coronavirus 2

Paden CR, Tao Y, Queen K, Zhang J, Li Y, Uehara A, Tong S.

Abstract:

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COVID-19 Severity Correlates with Weaker T Cell Immunity, Hypercytokinemia and Lung Epithelium Injury

Wang Z, Yang X, Zhou Y, Sun J, Liu X, Zhang J, Mei X, Zhong J, Zhao J, Ran P.

Abstract:

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In silico analysis and identification of promising hits against 2019 novel coronavirus 3C-like main protease enzyme

Chatterjee S, Maity A, Chowdhury S, Islam MA, Muttinini RK, Sen D.

Abstract:

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Comparison of In Vitro Inactivation of SARS CoV-2 with Hydrogen Peroxide and Povidone-Iodine Oral Antiseptic Rinses

Bidra AS, Pelletier JS, Westover JB, Frank S, Brown SM, Tessema B.

Abstract:

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A Comprehensive Review of Animal Models for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV

Singh A, Singh RS, Sarma P, Batra G, Joshi R, Kaur H, Sharma AR, Prakash A, Medhi B.

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The SARS-CoV-2 receptor, Angiotensin converting enzyme 2 (ACE2) is required for human endometrial stromal cell decidualization

Chadchan SB, Maurya VK, Popli P, Kommagani R.

Abstract:

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SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients

Klimstra WB, Tilston-Lunel NL, Nambulli S, Boslett J, McMillen CM, Gilliland T, Dunn MD, Sun C, Wheeler SE, Wells A, Hartman AL, McElroy AK, Reed DS, Rennick LJ, Duprex WP.

Abstract:

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Molecular Aspects of Co-morbidities in COVID-19 Infection

Pouya F, Imani Saber Z, Kerachian MA.

Abstract:

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Hypercytokinemia and Pathogen-Host Interaction in COVID-19

Badawi A.

Abstract:

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Potential Role of Nrf2 Activators with Dual Antiviral and Anti-Inflammatory Properties in the Management of Viral Pneumonia

Lin CY, Yao CA.

Abstract:

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Distinct stem/progenitor cells proliferate to regenerate the trachea, intrapulmonary airways and alveoli in COVID-19 patients

Fang Y, Liu H, Huang H, Li H, Saqi A, Qiang L, Que J.

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Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface

Shigdel UK, Lee SJ, Sowa ME, Bowman BR, Robison K, Zhou M, Pua KH, Stiles DT, Blodgett JAV, Udwary DW, Rajczewski AT, Mann AS, Mostafavi S, Hardy T, Arya S, Weng Z, Stewart M, Kenyon K, Morgenstern JP, Pan E, Gray DC, Pollock RM, Fry AM, Klausner RD, Townson SA, Verdine GL.

Abstract:

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Covid-19: Leicester placed under lockdown after spike in cases and hospital admissions

Mahase E.

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Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples

Xiao M, Liu X, Ji J, Li M, Li J, Yang L, Sun W, Ren P, Yang G, Zhao J, Liang T, Ren H, Chen T, Zhong H, Song W, Wang Y, Deng Z, Zhao Y, Ou Z, Wang D, Cai J, Cheng X, Feng T, Wu H, Gong Y, Yang H, Wang J, Xu X, Zhu S, Chen F, Zhang Y, Chen W, Li Y, Li J.

Abstract:

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A SARS-CoV-2 Coronavirus Nucleocapsid Antigen-Detecting Half-Strip Lateral Flow Assay Towards the Development of Point of Care Tests Using Commercially Available Reagents

Grant BD, Anderson CE, Williford JR, Alonzo LF, Glukhova VA, Boyle DS, Weigl BH, Nichols KP.

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Exploring Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors for Organ Protection in COVID-19

Fernandez-Fernandez B, D'Marco L, Górriz JL, Jacobs-Cachá C, Kanbay M, Luis-Lima S, Porrini E, Sarafidis P, Soler MJ, Ortiz A.

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SARS-CoV-2 Evolutionary Adaptation toward Host Entry and Recognition of Receptor O-Acetyl Sialylation in Virus-Host Interaction

Kim CH.

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Betacoronavirus Genomes: How Genomic Information has been Used to Deal with Past Outbreaks and the COVID-19 Pandemic

Llanes A, Restrepo CM, Caballero Z, Rajeev S, Kennedy MA, Lleonart R.

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CoViD-19 epidemic follows the "kinetics" of enzymes with cooperative substrate binding

Silverstein TP.

Abstract:

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A distance learning enzyme assay and kinetics laboratory in the time of COVID-19

Papaneophytou C.

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Virtual laboratory lessons in enzymology

Quesada V.

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Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention

Hall MW, Joshi I, Leal L, Ooi EE.

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Myelin Oligodendrocyte Glycoprotein antibody-associated optic neuritis and myelitis in COVID-19

Zhou S, Jones-Lopez EC, Soneji DJ, Azevedo CJ, Patel VR.

Abstract:

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Absence of Severe Acute Respiratory Syndrome-Coronavirus-2 RNA in Human Corneal Tissues

Bayyoud T, Iftner A, Iftner T, Bartz-Schmidt KU, Rohrbach JM, Ueffing M, Schindler M, Thaler S.

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SARS-CoV-2 pathophysiology and assessment of coronaviruses in CNS diseases with a focus on therapeutic targets

Vallamkondu J, John A, Wani WY, Ramadevi S, Jella KK, Reddy PH, Kandimalla R.

Abstract:

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Antibody responses against SARS-CoV-2 in COVID-19 patients

Liu A, Li Y, Peng J, Huang Y, Xu D.

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Emerging vaccine delivery systems for COVID-19: Functionalised silica nanoparticles offer a potentially safe and effective alternative delivery system for DNA/RNA vaccines and may be useful in the hunt for a COVID-19 vaccine

Theobald N.

Abstract:

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Comparative analysis of protein synthesis rate in COVID-19 with other human coronaviruses

Dasari CM, Bhukya R.

Abstract:

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Identifying phenotypes of COVID-19, defining their pathogenesis, and targeting treatments could improve outcomes

Rajendram R, Kharal GA, Mahmood N, Kharal M.

Abstract:

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Identification of a Potential Peptide Inhibitor of SARS-CoV-2 Targeting its Entry into the Host Cells

Baig MS, Alagumuthu M, Rajpoot S, Saqib U.

Abstract:

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COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis

Chua RL, Lukassen S, Trump S, Hennig BP, Wendisch D, Pott F, Debnath O, Thürmann L, Kurth F, Völker MT, Kazmierski J, Timmermann B, Twardziok S, Schneider S, Machleidt F, Müller-Redetzky H, Maier M, Krannich A, Schmidt S, Balzer F, Liebig J, Loske J, Suttorp N, Eils J, Ishaque N, Liebert UG, von Kalle C, Hocke A, Witzenrath M, Goffinet C, Drosten C, Laudi S, Lehmann I, Conrad C, Sander LE, Eils R.

Abstract:

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Door to the cell for COVID-19 opened, leading way to therapies

Huang Z, Chai J.

Abstract:

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Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

Weiskopf D, Schmitz KS, Raadsen MP, Grifoni A, Okba NMA, Endeman H, van den Akker JPC, Molenkamp R, Koopmans MPG, van Gorp ECM, Haagmans BL, de Swart RL, Sette A, de Vries RD.

Abstract:

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Persistence of Bacteriophage Phi 6 on Porous and Non-Porous Surfaces; Potential for use as Ebola or Coronavirus Surrogate

Whitworth C, Mu Y, Houston H, Martinez-Smith M, Noble-Wang J, Coulliette-Salmond A, Rose L.

Abstract:

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Targeting adenosinergic pathway and adenosine A(2A) receptor signaling for the treatment of COVID-19: A hypothesis

Abouelkhair MA.

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Endothelial progenitor cells and mesenchymal stem cells to overcome vascular deterioration and cytokine storm in critical patients with COVID-19

Karaahmet F, Kocaman SA.

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The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway

Li JY, Liao CH, Wang Q, Tan YJ, Luo R, Qiu Y, Ge XY.

Abstract:

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COVID-19: A series of important recent clinical and laboratory reports in immunology and pathogenesis of SARS-CoV-2 infection and care of allergy patients

Pfaar O, Torres MJ, Akdis CA.

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Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19

Parhizkar Roudsari P, Alavi-Moghadam S, Payab M, Sayahpour FA, Aghayan HR, Goodarzi P, Mohamadi-Jahani F, Larijani B, Arjmand B.

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Genome sequencing of the first SARS-CoV-2 reported from patients with COVID-19 in Ecuador

Marquez S, Prado-Vivar B, Guadalupe JJ, Gutierrez Granja B, Jibaja M, Tobar M, Mora F, Gaviria J, Garcia M, Ligna E, Espinosa F, Reyes J, Barragan V, Rojas-Silva P, Trueba G, Grunauer M, Cardenas P.

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Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis

Maremanda KP, Sundar IK, Li D, Rahman I.

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Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs

Kern DM, Sorum B, Hoel CM, Sridharan S, Remis JP, Toso DB, Brohawn SG.

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Effects of Renin-Angiotensin Inhibition on ACE2 and TMPRSS2 Expression: Insights into COVID-19

Wu C, Ye D, Mullick AE, Li Z, Danser AHJ, Daugherty A, Lu HS.

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Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis

Herrera NG, Morano NC, Celikgil A, Georgiev GI, Malonis RJ, Lee JH, Tong K, Vergnolle O, Massimi AB, Yen LY, Noble AJ, Kopylov M, Bonanno JB, Garrett-Thomson SC, Hayes DB, Bortz RH, Wirchnianski AS, Florez C, Laudermilch E, Haslwanter D, Fels JM, Dieterle ME, Jangra RK, Barnhill J, Mengotto A, Kimmel D, Daily JP, Pirofski LA, Chandran K, Brenowitz M, Garforth SJ, Eng ET, Lai JR, Almo SC.

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Structural and functional conservation of the programmed -1 ribosomal frameshift signal of SARS-CoV-2

Kelly JA, Olson AN, Neupane K, Munshi S, Emeterio JS, Pollack L, Woodside MT, Dinman JD.

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Comparative analysis of coronavirus genomic RNA structure reveals conservation in SARS-like coronaviruses

Sanders W, Fritch EJ, Madden EA, Graham RL, Vincent HA, Heise MT, Baric RS, Moorman NJ.

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Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate

Iserman C, Roden C, Boerneke M, Sealfon R, McLaughlin G, Jungreis I, Park C, Boppana A, Fritch E, Hou YJ, Theesfeld C, Troyanskaya OG, Baric RS, Sheahan TP, Weeks K, Gladfelter AS.

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Novel ACE2-IgG1 fusions with improved activity against SARS-CoV2

Iwanaga N, Cooper L, Rong L, Beddingfield B, Crabtree J, Tripp RA, Kolls JK.

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Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4 (+) T cells

Meckiff BJ, Ramírez-Suástegui C, Fajardo V, Chee SJ, Kusnadi A, Simon H, Grifoni A, Pelosi E, Weiskopf D, Sette A, Ay F, Seumois G, Ottensmeier CH, Vijayanand P.

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The IMEx Coronavirus interactome: an evolving map of Coronaviridae-Host molecular interactions

Perfetto L, Pastrello C, Del-Toro N, Duesbury M, Iannuccelli M, Kotlyar M, Licata L, Meldal B, Panneerselvam K, Panni S, Rahimzadeh N, Ricard-Blum S, Salwinski L, Shrivastava A, Cesareni G, Pellegrini M, Orchard S, Jurisica I, Hermjakob HH, Porras P.

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The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

Beddingfield B, Iwanaga N, Zheng W, Roy CJ, Hu TY, Kolls J, Bix G.

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The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in vitro models of the human blood-brain barrier

Buzhdygan TP, DeOre BJ, Baldwin-Leclair A, McGary H, Razmpour R, Galie PA, Potula R, Andrews AM, Ramirez SH.

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SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics

Gupta R, Charron J, Stenger CL, Painter J, Steward H, Cook TW, Faber W, Frisch A, Lind E, Bauss J, Li X, Sirpilla O, Soehnlen X, Underwood A, Hinds D, Morris M, Lamb N, Carcillo JA, Bupp CP, Uhal BD, Rajasekaran S, Prokop JW.

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Genome Sequence of SARS-CoV-2 Isolate Cali-01, from Colombia, Obtained Using Oxford Nanopore MinION Sequencing

Lopez-Alvarez D, Parra B, Cuellar WJ.

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COVID-19 chilblain-like lesion: immunohistochemical demonstration of SARS-CoV-2 spike protein in blood vessel endothelium and sweat gland epithelium in a PCR-negative patient

Santonja C, Heras F, Núñez L, Requena L.

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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Huo J, Zhao Y, Ren J, Zhou D, Duyvesteyn HME, Ginn HM, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Tan TK, Rijal P, Coombes N, Bewley KR, Tree JA, Radecke J, Paterson NG, Supasa P, Mongkolsapaya J, Screaton GR, Carroll M, Townsend A, Fry EE, Owens RJ, Stuart DI.

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An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening

Amanat F, White KM, Miorin L, Strohmeier S, McMahon M, Meade P, Liu WC, Albrecht RA, Simon V, Martinez-Sobrido L, Moran T, García-Sastre A, Krammer F.

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Immunology of COVID-19: mechanisms, clinical outcome, diagnostics and perspectives - a report of the European Academy of Allergy and Clinical Immunology (EAACI)

Sokolowska M, Lukasik Z, Agache I, Akdis CA, Akdis D, Akdis M, Barcik W, Brough H, Eiwegger T, Eliaszewicz A, Eyerich S, Feleszko W, Gomez Casado C, Hoffmann-Sommergruber K, Janda J, Jiménez-Saiz R, Jutel M, Knol E, Kortekaas Krohn I, Kothari A, Makowska J, Moniuszko M, Morita H, O'Mahony L, Nadeau K, Ozdemir C, Pali-Schöll I, Palomares O, Papaleo F, Prunicki M, Schmidt-Weber CB, Sediva A, Schwarze J, Shamji MH, Tramper-Stranders G, van W, de Veen, Untersmayr E.

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LIPS method for the detection of SARS-CoV-2 antibodies to spike and nucleocapsid proteins

Haljasmägi L, Remm A, Rumm AP, Krassohhina E, Sein H, Tamm A, Kisand K, Peterson P.

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A cluster of COVID-19 in pilgrims to Israel

Pavli A, Smeti P, Papadima K, Andreopoulou A, Hadjianastasiou S, Triantafillou E, Vakali A, Kefaloudi C, Pervanidou D, Gogos C, Maltezou HC.

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Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine

Lizbeth RG, Jazmín GM, José CB, Marlet MA.

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COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure

Marchetti M.

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Elevated Serum Endothelial Cell Adhesion Molecules Expression in COVID-19 Patients

Tong M, Jiang Y, Xia D, Xiong Y, Zheng Q, Chen F, Zou L, Xiao W, Zhu Y.

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ACE2, Much More Than Just a Receptor for SARS-COV-2

Samavati L, Uhal BD.

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Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes

Lopera Maya EA, van der Graaf A, Lanting P, van der Geest M, Fu J, Swertz M, Franke L, Wijmenga C, Deelen P, Zhernakova A, Sanna S; Lifelines Cohort Study.

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Antibody Dependent Enhancement Due to Original Antigenic Sin and the Development of SARS

Fierz W, Walz B.

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SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise

Sekizuka T, Kuramoto S, Nariai E, Taira M, Hachisu Y, Tokaji A, Shinohara M, Kishimoto T, Itokawa K, Kobayashi Y, Kadokura K, Kamiya H, Matsui T, Suzuki M, Kuroda M.

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Structural plasticity of SARS-CoV-2 3CL M(pro) active site cavity revealed by room temperature X-ray crystallography

Kneller DW, Phillips G, O'Neill HM, Jedrzejczak R, Stols L, Langan P, Joachimiak A, Coates L, Kovalevsky A.

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Targeting lymphocyte Kv1.3-channels to suppress cytokine storm in severe COVID-19: Can it be a novel therapeutic strategy?

Kazama I.

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Rampant C‚ÜíU Hypermutation in the Genomes of SARS-CoV-2 and Other Coronaviruses: Causes and Consequences for Their Short- and Long-Term Evolutionary Trajectories

Simmonds P.

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Paromomycin: a potential dual targeted drug effectively inhibits both Spike (S1) and Main Protease of COVID-19

Tariq A, Mateen RM, Afzal MS, Saleem M.

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A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S.

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SARS-CoV-2 and SARS-CoV: Virtual Screening of Potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12)

Ruan Z, Liu C, Guo Y, He Z, Huang X, Jia X, Yang T.

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In Vivo Expressed Biologics for Infectious Disease Prophylaxis: Rapid Delivery of DNA-Based Antiviral Antibodies

Andrews CD, Huang Y, Ho DD, Liberatore RA.

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In-silico investigation of phytochemicals from Asparagus racemosus as plausible antiviral agent in COVID-19

Chikhale RV, Sinha SK, Patil RB, Prasad SK, Shakya A, Gurav N, Prasad R, Dhaswadikar SR, Wanjari M, Gurav SS.

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Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CL(pro)

Alamri MA, Tahir Ul Qamar M, Mirza MU, Bhadane R, Alqahtani SM, Muneer I, Froeyen M, Salo-Ahen OMH.

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Molecular Basis for ADP-ribose Binding to the Mac1 Domain of SARS-CoV-2 Nsp3

Frick DN, Virdi RS, Vuksanovic N, Dahal N, Silvaggi NR.

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Nanopore Targeted Sequencing for the Accurate and Comprehensive Detection of SARS-CoV-2 and Other Respiratory Viruses

Wang M, Fu A, Hu B, Tong Y, Liu R, Liu Z, Gu J, Xiang B, Liu J, Jiang W, Shen G, Zhao W, Men D, Deng Z, Yu L, Wei W, Li Y, Liu T.

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Introduction: microbes, networks, knowledge-disease ecology and emerging infectious diseases in time of COVID-19

Honigsbaum M, Méthot PO.

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An Aberration Detection-Based Approach for Sentinel Syndromic Surveillance of COVID-19 and Other Novel Influenza-Like Illnesses

Wen A, Wang L, He H, Liu S, Fu S, Sohn S, Kugel JA, Kaggal VC, Huang M, Wang Y, Shen F, Fan J, Liu H.

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Plasma from recovered COVID19 subjects inhibits spike protein binding to ACE2 in a microsphere-based inhibition assay

Gniffke EP, Harrington WE, Dambrauskas N, Jiang Y, Trakhimets O, Vigdorovich V, Frenkel L, Sather DN, Smith SEP.

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Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

Ortiz Bezara ME, Thurman A, Pezzulo AA, Leidinger MR, Klesney-Tait JA, Karp PH, Tan P, Wohlford-Lenane C, McCray PB Jr, Meyerholz DK.

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SARS-CoV-2-specific T cells exhibit unique features characterized by robust helper function, lack of terminal differentiation, and high proliferative potential

Neidleman J, Luo X, Frouard J, Xie G, Gurjot G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR.

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Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma

Salazar E, Kuchipudi SV, Christensen PA, Eagar TN, Yi X, Zhao P, Jin Z, Long SW, Olsen RJ, Chen J, Castillo B, Leveque C, Towers DM, Lavinder J, Gollihar JD, Cardona J, Ippolito GC, Nissly RH, Bird IM, Greenawalt D, Rossi RM, Gontu A, Srinivasan S, Poojary IB, Cattadori IM, Hudson PJ, Joselyn N, Prugar L, Huie K, Herbert A, Bernard DW, Dye J, Kapur V, Musser JM.

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Closing coronavirus spike glycoproteins by structure-guided design

McCallum M, Walls AC, Corti D, Veesler D.

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Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, Le KC, Wrapp D, Lee AG, Liu Y, Chou CW, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Park J, Wang N, Amengor D, Maynard JA, Finkelstein IJ, McLellan JS.

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CoV3D: A database of high resolution coronavirus protein structures

Gowthaman R, Guest JD, Yin R, Adolf-Bryfogle J, Schief WR, Pierce BG.

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SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models

Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Maria Della Corte C, Fan Y, Kundu K, Pickering CR, Johnson FM, Zhang J, Kadara H, Minna JD, Gibbons DL, Wang J, Heymach JV, Byers LA.

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Origin and cross-species transmission of bat coronaviruses in China

Latinne A, Hu B, Olival KJ, Zhu G, Zhang L, Li H, Chmura AA, Field HE, Zambrana-Torrelio C, Epstein JH, Li B, Zhang W, Wang LF, Shi ZL, Daszak P.

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Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19

Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Frum T, Kadambi NS, Amin AT, O'Meara TR, Pretto CD, Spence JR, Huang J, Alysandratos KD, Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O'Meara MJ, Sexton JZ.

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Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping

Credle JJ, Robinson ML, Gunn J, Monaco D, Sie B, Tchir A, Hardick J, Zheng X, Shaw-Saliba K, Rothman RE, Eshleman SH, Pekosz A, Hansen K, Mostafa H, Steinegger M, Larman HB.

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Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A.

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The utility of native MS for understanding the mechanism of action of repurposed therapeutics in COVID-19: heparin as a disruptor of the SARS-CoV-2 interaction with its host cell receptor

Yang Y, Du Y, Kaltashov IA.

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Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR, Koranda N, Gristick HB, Gaebler C, Muecksch F, Cetrulo Lorenzi JC, Finkin S, Hagglof T, Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey M, Robbiani DF, Nussenzweig MC, Bjorkman PJ.

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Shielding and Beyond: The Roles of Glycans in SARS-CoV-2 Spike Protein

Casalino L, Gaieb Z, Dommer AC, Harbison AM, Fogarty CA, Barros EP, Taylor BC, Fadda E, Amaro RE.

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Sarbecovirus comparative genomics elucidates gene content of SARS-CoV-2 and functional impact of COVID-19 pandemic mutations

Jungreis I, Sealfon R, Kellis M.

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Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike

Prévost J, Gasser R, Beaudoin-Bussières G, Richard J, Duerr R, Laumaea A, Anand SP, Goyette G, Ding S, Medjahed H, Lewin A, Perreault J, Tremblay T, Gendron-Lepage G, Gauthier N, Carrier M, Marcoux D, Piché A, Lavoie M, Benoit A, Loungnarath V, Brochu G, Desforges M, Talbot PJ, Gould Maule GT, Côté M, Therrien C, Serhir B, Bazin R, Roger M, Finzi A.

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Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors

Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C.

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SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

Corbett KS, Edwards D, Leist SR, Abiona OM, Boyoglu-Barnum S, Gillespie RA, Himansu S, Schäfer A, Ziwawo CT, DiPiazza AT, Dinnon KH, Elbashir SM, Shaw CA, Woods A, Fritch EJ, Martinez DR, Bock KW, Minai M, Nagata BM, Hutchinson GB, Bahl K, Garcia-Dominguez D, Ma L, Renzi I, Kong WP, Schmidt SD, Wang L, Zhang Y, Stevens LJ, Phung E, Chang LA, Loomis RJ, Altaras NE, Narayanan E, Metkar M, Presnyak V, Liu C, Louder MK, Shi W, Leung K, Yang ES, West A, Gully KL, Wang N, Wrapp D, Doria-Rose NA, Stew

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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation

Hurlburt NK, Wan YH, Stuart AB, Feng J, McGuire AT, Stamatatos L, Pancera M.

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Preventing SARS-CoV-2 infection by blocking a tissue serine protease

Jankousky KC, Schultz J, Windham S, Henao-Martínez AF, Franco-Paredes C, Shapiro L.

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The Nrf2 Activator (DMF) and Covid-19: Is there a Possible Role?

Hassan SM, Jawad MJ, Ahjel SW, Singh RB, Singh J, Awad SM, Hadi NR.

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Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells

Senthil Kumar KJ, Gokila Vani M, Wang CS, Chen CC, Chen YC, Lu LP, Huang CH, Lai CS, Wang SY.

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Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory response

Bock JO, Ortea I.

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Mitochondria and Microbiota dysfunction in COVID-19 pathogenesis

Saleh J, Peyssonnaux C, Singh KK, Edeas M.

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Discovering small-molecule therapeutics against SARS-CoV-2

Tiwari V, Beer JC, Sankaranarayanan NV, Swanson-Mungerson M, Desai UR.

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Letter to the editor: Immunomodulation by phsphodiesterase-4 inhibitor in COVID-19 patients

Santaniello A, Vigone B, Beretta L.

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May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence

Annunziata G, Sanduzzi Zamparelli M, Santoro C, Ciampaglia R, Stornaiuolo M, Tenore GC, Sanduzzi A, Novellino E.

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Methylation Pathways and SARS-CoV-2 Lung Infiltration and Cell Membrane-Virus Fusion Are Both Subject to Epigenetics

Pruimboom L.

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Innate Immune Signaling and Proteolytic Pathways in the Resolution or Exacerbation of SARS-CoV-2 in Covid-19: Key Therapeutic Targets?

Sallenave JM, Guillot L.

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COVID-19 and SARS Coronavirus 2: Antibodies for the Immediate Rescue and Recovery Phase

Halstead SB, Akkina R.

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An Open Question: Is It Rational to Inhibit the mTor-Dependent Pathway as COVID-19 Therapy?

Terrazzano G, Rubino V, Palatucci AT, Giovazzino A, Carriero F, Ruggiero G.

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ACE2 and TMPRSS2 variation in savanna monkeys (Chlorocebus spp.): Potential risk for zoonotic/anthroponotic transmission of SARS-CoV-2 and a potential model for functional studies

Schmitt CA, Bergey CM, Jasinska AJ, Ramensky V, Burt F, Svardal H, Jorgensen MJ, Freimer NB, Grobler JP, Turner TR.

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Can nanotechnology help in the fight against COVID-19?

Palestino G, García-Silva I, González-Ortega O, Rosales-Mendoza S.

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Elucidation of Cellular Targets and Exploitation of the Receptor Binding Domain of SARS-CoV-2 for vaccine and monoclonal antibody synthesis

Baig AM, Khaleeq A, Hira S.

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Platelet Gene Expression and Function in COVID-19 Patients

Manne BK, Denorme F, Middleton EA, Portier I, Rowley JW, Stubben CJ, Petrey AC, Tolley ND, Guo L, Cody MJ, Weyrich AS, Yost CC, Rondina MT, Campbell RA.

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Targeting SARS-COV-2 non-structural protein 16: a virtual drug repurposing study

Tazikeh-Lemeski E, Moradi S, Raoufi R, Shahlaei M, Janlou MAM, Zolghadri S.

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Molecular diagnosis of COVID-19: Challenges and research needs

Feng W, Newbigging A, Le C, Pang B, Peng H, Cao Y, Wu J, Abbas G, Song J, Wang DB, Cui M, Tao J, Tyrrell DL, Zhang XE, Zhang H, Le XC.

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Phosphodiesterase Type 5 Inhibitors and COVID-19: Are They Useful In Disease Managment?

Mondaini N.

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Application of System Biology to Explore the Association of Neprilysin, Angiotensin-Converting Enzyme 2 (ACE2), and Carbonic Anhydrase (CA) in Pathogenesis of SARS-CoV-2

Zolfaghari Emameh R, Falak R, Bahreini E.

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A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression

Polak SB, Van Gool IC, Cohen D, von der Thüsen JH, van Paassen J.

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Validation of a digital pathology system including remote review during the COVID-19 pandemic

Hanna MG, Reuter VE, Ardon O, Kim D, Sirintrapun SJ, Schüffler PJ, Busam KJ, Sauter JL, Brogi E, Tan LK, Xu B, Bale T, Agaram NP, Tang LH, Ellenson LH, Philip J, Corsale L, Stamelos E, Friedlander MA, Ntiamoah P, Labasin M, England C, Klimstra DS, Hameed M.

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Structural and functional conservation of the programmed -1 ribosomal frameshift signal of SARS coronavirus 2 (SARS-CoV-2)

Kelly JA, Olson AN, Neupane K, Munshi S, San Emeterio J, Pollack L, Woodside MT, Dinman JD.

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A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

Chi X, Yan R, Zhang J, Zhang G, Zhang Y, Hao M, Zhang Z, Fan P, Dong Y, Yang Y, Chen Z, Guo Y, Zhang J, Li Y, Song X, Chen Y, Xia L, Fu L, Hou L, Xu J, Yu C, Li J, Zhou Q, Chen W.

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A case report of SARS-CoV-2 confirmed in saliva specimens up to 37 days after onset: Proposal of saliva specimens for COVID-19 diagnosis and virus monitoring

Tajima Y, Suda Y, Yano K.

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Molecular Targets in the Chemotherapy of Coronavirus Infection

Zhirnov OP.

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Drug repurposing against SARS-CoV-2 using E-pharmacophore based virtual screening, molecular docking and molecular dynamics with main protease as the target

Arun KG, Sharanya CS, Abhithaj J, Francis D, Sadasivan C.

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Nanotechnology for COVID-19: Therapeutics and Vaccine Research

Chauhan G, Madou MJ, Kalra S, Chopra V, Ghosh D, Martinez-Chapa SO.

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Differences of SARS-CoV-2 Shedding Duration in Sputum and Nasopharyngeal Swab Specimens among Adult Inpatients with COVID-19

Wang K, Zhang X, Sun J, Ye J, Wang F, Hua J, Zhang H, Shi T, Li Q, Wu X.

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COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles' heel conserved region to minimize probability of escape mutations and drug resistance

Robson B.

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Remdesivir (GS-5734) as a therapeutic option of 2019-nCOV main protease - in silico approach

Naik VR, Munikumar M, Ramakrishna U, Srujana M, Goudar G, Naresh P, Kumar BN, Hemalatha R.

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Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules as papain-like protease (PLpro) inhibitors

Amin SA, Ghosh K, Gayen S, Jha T.

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Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors - an in silico docking and molecular dynamics simulation study

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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Virtual screening and dynamics of potential inhibitors targeting RNA binding domain of nucleocapsid phosphoprotein from SARS-CoV-2

Yadav R, Imran M, Dhamija P, Suchal K, Handu S.

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Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approach

Chikhale RV, Gurav SS, Patil RB, Sinha SK, Prasad SK, Shakya A, Shrivastava SK, Gurav NS, Prasad RS.

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Letter to the Editor: Addressing test security issues pertaining to reuse of closed-book summative assessment items possibly compromised during the COVID-19 pandemic

Prakash ES, Kacsoh B.

Abstract:

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Promising inhibitors of main protease of novel corona virus to prevent the spread of COVID-19 using docking and molecular dynamics simulation

Kumar D, Kumari K, Vishvakarma VK, Jayaraj A, Kumar D, Ramappa VK, Patel R, Kumar V, Dass SK, Chandra R, Singh P.

Abstract:

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In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2

Prasanth DSNBK, Murahari M, Chandramohan V, Panda SP, Atmakuri LR, Guntupalli C.

Abstract:

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Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19

Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK.

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Constituents of buriti oil (Mauritia flexuosa L.) like inhibitors of the SARS-Coronavirus main peptidase: an investigation by docking and molecular dynamics

Costa AN, de Sá ÉRA, Bezerra RDS, Souza JL, Lima FDCA.

Abstract:

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Perspectives on the development of neutralizing antibodies against SARS-CoV-2

Ho M.

Abstract:

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Novel SARS-CoV-2/COVID-19: Origin, pathogenesis, genes and genetic variations, immune responses and phylogenetic analysis

Junejo Y, Ozaslan M, Safdar M, Khailany RA, Rehman S, Yousaf W, Khan MA.

Abstract:

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Re-appearance of the SARS-CoV-2 virus nucleic acid in patients recovering from COVID-19

Wang L, Ji F, Li C, Pan X, Yan X, Wang R, Gu B.

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Novel COVID-19: A Comprehensive Review of Transmission, Manifestation, and Pathogenesis

Hussain A, Kaler J, Tabrez E, Tabrez S, Tabrez SSM.

Abstract:

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Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach

Loganathan T, Ramachandran S, Shankaran P, Nagarajan D, Mohan S S.

Abstract:

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Time series prediction of COVID-19 by mutation rate analysis using recurrent neural network-based LSTM model

Pathan RK, Biswas M, Khandaker MU.

Abstract:

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Update on the target structures of SARS-CoV-2: A systematic review

Prajapat M, Sarma P, Shekhar N, Prakash A, Avti P, Bhattacharyya A, Kaur H, Kumar S, Bansal S, Sharma AR, Medhi B.

Abstract:

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Effects of Micronutrients or Conditional Amino Acids on COVID-19-Related Outcomes: An Evidence Analysis Center Scoping Review

Rozga M, Cheng FW, Moloney L, Handu D.

Abstract:

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When interferon tiptoes through COVID-19: Pernio-like lesions and their prognostic implications during SARS-CoV-2 infection

Damsky W, Peterson D, King B.

Abstract:

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Tackling SARS-CoV-2: proposed targets and repurposed drugs

Joshi S, Joshi M, Degani MS.

Abstract:

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Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19)

Umakanthan S, Sahu P, Ranade AV, Bukelo MM, Rao JS, Abrahao-Machado LF, Dahal S, Kumar H, Kv D.

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Deceiving SARS-CoV-2 molecular-tropism clues - A combinational contemporary strategy

Balaji A, Bhuvaneswari S, Kumar DN.

Abstract:

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Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase

Ahmed-Belkacem R, Sutto-Ortiz P, Guiraud M, Canard B, Vasseur JJ, Decroly E, Debart F.

Abstract:

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Pathological Findings in the Testes of COVID-19 Patients: Clinical Implications

Yang M, Chen S, Huang B, Zhong JM, Su H, Chen YJ, Cao Q, Ma L, He J, Li XF, Li X, Zhou JJ, Fan J, Luo DJ, Chang XN, Arkun K, Zhou M, Nie X.

Abstract:

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Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation

Jääskeläinen AJ, Kuivanen S, Kekäläinen E, Ahava MJ, Loginov R, Kallio-Kokko H, Vapalahti O, Jarva H, Kurkela S, Lappalainen M.

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Tackle the free radicals damage in COVID-19

Wu J.

Abstract:

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A Library of Nucleotide Analogues Terminate RNA Synthesis Catalyzed by Polymerases of Coronaviruses that Cause SARS and COVID-19

Jockusch S, Tao C, Li X, Anderson TK, Chien M, Kumar S, Russo JJ, Kirchdoerfer RN, Ju J.

Abstract:

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Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management?

Sureda A, Alizadeh J, Nabavi SF, Berindan Neagoe I, Cismaru CA, Jeandet P, Los MJ, Clementi E, Nabavi SM, Ghavami S.

Abstract:

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In silico prediction of potential inhibitors for the Main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repurposing

Kumar Y, Singh H, Patel CN.

Abstract:

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Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation

Seydoux E, Homad LJ, MacCamy AJ, Parks KR, Hurlburt NK, Jennewein MF, Akins NR, Stuart AB, Wan YH, Feng J, Whaley RE, Singh S, Boeckh M, Cohen KW, McElrath MJ, Englund JA, Chu HY, Pancera M, McGuire AT, Stamatatos L.

Abstract:

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Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane

Woo H, Park SJ, Choi YK, Park T, Tanveer M, Cao Y, Kern NR, Lee J, Yeom MS, Croll TI, Seok C, Im W.

Abstract:

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Subversion of host stress granules by coronaviruses: Potential roles of π-rich disordered domains of viral nucleocapsids

Muhammad Moosa M, Banerjee PR.

Abstract:

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Distinct infection process of SARS-CoV-2 in human bronchial epithelial cells line

Liao Y, Li X, Mou T, Zhou X, Li D, Wang L, Zhang Y, Dong X, Zheng H, Guo L, Liang Y, Jiang G, Fan S, Xu X, Xie Z, Chen H, Liu L, Li Q.

Abstract:

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[SARS-CoV-2 protease: an excellent target to develop drugs against COVID-19]

Ladoux A, Azoulay S, Dani C.

Abstract:

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Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2

Banerjee A, Nasir JA, Budylowski P, Yip L, Aftanas P, Christie N, Ghalami A, Baid K, Raphenya AR, Hirota JA, Miller MS, McGeer AJ, Ostrowski M, Kozak RA, McArthur AG, Mossman K, Mubareka S.

Abstract:

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Genomewide Association Study of Severe Covid-19 with Respiratory Failure

Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE, Rodriguez-Frias F, Zanella A, Bandera A, Protti A, Aghemo A, Lleo A, Biondi A, Caballero-Garralda A, Gori A, Tanck A, Carreras Nolla A, Latiano A, Fracanzani AL, Peschuck A, Julià A, Pesenti A, Voza A, Jiménez D, Mate

Abstract:

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Genetic variability of human angiotensin-converting enzyme 2 (hACE2) among various ethnic populations

Li Q, Cao Z, Rahman P.

Abstract:

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SARS-COV-2 As Possible Inducer of Viral Reactivations

Ciccarese G, Parodi A, Drago F.

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Individual variation of the SARS-CoV-2 receptor ACE2 gene expression and regulation

Chen J, Jiang Q, Xia X, Liu K, Yu Z, Tao W, Gong W, Han JJ.

Abstract:

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SARS CoV-2 aggravates cellular metabolism mediated complications in COVID-19 infection

Singh Y, Gupta G, Kazmi I, Al-Abbasi FA, Negi P, Chellappan D, Dua K.

Abstract:

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Update on possible animal sources for COVID-19 in humans

Opriessnig T, Huang YW.

Abstract:

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Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences

Narkhede RR, Pise AV, Cheke RS, Shinde SD.

Abstract:

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Convergent antibody responses to SARS-CoV-2 in convalescent individuals

Robbiani DF, Gaebler C, Muecksch F, Lorenzi JCC, Wang Z, Cho A, Agudelo M, Barnes CO, Gazumyan A, Finkin S, Hägglöf T, Oliveira TY, Viant C, Hurley A, Hoffmann HH, Millard KG, Kost RG, Cipolla M, Gordon K, Bianchini F, Chen ST, Ramos V, Patel R, Dizon J, Shimeliovich I, Mendoza P, Hartweger H, Nogueira L, Pack M, Horowitz J, Schmidt F, Weisblum Y, Michailidis E, Ashbrook AW, Waltari E, Pak JE, Huey-Tubman KE, Koranda N, Hoffman PR, West AP Jr, Rice CM, Hatziioannou T, Bjorkman PJ, Bieniasz PD, C

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Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?

Huertas A, Montani D, Savale L, Pichon J, Tu L, Parent F, Guignabert C, Humbert M.

Abstract:

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In Vitro and Animal Models for SARS-CoV-2 research

Takayama K.

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A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, Fremont DH, Greco S, McCray PB Jr, Perlman S, Holtzman MJ, Ellebedy AH, Diamond MS.

Abstract:

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Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins

Swaim CD, Canadeo LA, Monte KJ, Khanna S, Lenschow DJ, Huibregtse JM.

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Natural compounds from Clerodendrum spp. as possible therapeutic candidates against SARS-CoV-2: An in silico investigation

Kar P, Sharma NR, Singh B, Sen A, Roy A.

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Identification of a novel dual-target scaffold for 3CLpro and RdRp proteins of SARS-CoV-2 using 3D-similarity search, molecular docking, molecular dynamics and ADMET evaluation

Aouidate A, Ghaleb A, Chtita S, Aarjane M, Ousaa A, Maghat H, Sbai A, Choukrad M, Bouachrine M, Lakhlifi T.

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Identification of bioactive compounds from Glycyrrhiza glabra as possible inhibitor of SARS-CoV-2 spike glycoprotein and non-structural protein-15: a pharmacoinformatics study

Sinha SK, Prasad SK, Islam MA, Gurav SS, Patil RB, AlFaris NA, Aldayel TS, AlKehayez NM, Wabaidur SM, Shakya A.

Abstract:

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The impact of nanotechnology in the current universal COVID-19 crisis. Let's not forget nanosafety!

Valdiglesias V, Laffon B.

Abstract:

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Effects of Gene-Eden-VIR and Novirin on SARS-CoV: Implications for COVID-19

Polansky H, Lori G.

Abstract:

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Cellular Nanosponges Inhibit SARS-CoV-2 Infectivity

Zhang Q, Honko A, Zhou J, Gong H, Downs SN, Vasquez JH, Fang RH, Gao W, Griffiths A, Zhang L.

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Critical Differences Between the Binding Features of the Spike Proteins of SARS-CoV-2 and SARS-CoV

Bai C, Warshel A.

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The discovery of a putative allosteric site in SARS-CoV-2 spike protein by an integrated structural/dynamical approach

Di Paola L, Hadi-Alijanvand H, Song X, Hu G, Giuliani A.

Abstract:

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Opportunities and Challenges for Biosensors and Nanoscale Analytical Tools for Pandemics: COVID-19

Bhalla N, Pan Y, Yang Z, Payam AF.

Abstract:

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SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways

Sungnak W, Huang N, Bécavin C, Berg M; HCA Lung Biological Network.

Abstract:

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Pathological Findings and Management of COVID-19 Patients: A Brief Overview of Modern-day Pandemic

Mian MS, Razaq L, Khan S, Hussain N, Razaq M.

Abstract:

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A Putative Role of de-Mono-ADP-Ribosylation of STAT1 by the SARS-CoV-2 Nsp3 Protein in the Cytokine Storm Syndrome of COVID-19

Claverie JM.

Abstract:

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Do sex-specific immunobiological factors and differences in angiotensin converting enzyme 2 (ACE2) expression explain increased severity and mortality of COVID-19 in males?

Vikse J, Lippi G, Henry BM.

Abstract:

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Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents

Dormont F, Brusini R, Cailleau C, Reynaud F, Peramo A, Gendron A, Mougin J, Gaudin F, Varna M, Couvreur P.

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Prevalence of antibodies against COVID-19 in the staff of a COVID-19 regular ward

Harsch IA, Skiba M, Konturek PC, Epstude J.

Abstract:

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Immune status could determine efficacy of COVID-19 therapies

Cully M.

Abstract:

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Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis

Wu J, Song D, Li Z, Guo B, Xiao Y, Liu W, Liang L, Feng C, Gao T, Chen Y, Li Y, Wang Z, Wen J, Yang S, Liu P, Wang L, Wang Y, Peng L, Stacey GN, Hu Z, Feng G, Li W, Huo Y, Jin R, Shyh-Chang N, Zhou Q, Wang L, Hu B, Dai H, Hao J.

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The Nucleocapsid Protein of SARS-CoV-2: a Target for Vaccine Development

Dutta NK, Mazumdar K, Gordy JT.

Abstract:

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Ig-like ACE2 protein therapeutics: A revival in development during the COVID-19 pandemic

Qian K, Hu S.

Abstract:

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De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

Huang X, Pearce R, Zhang Y.

Abstract:

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ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection

Zhou L, Xu Z, Castiglione GM, Soiberman US, Eberhart CG, Duh EJ.

Abstract:

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Pangolins Harbor SARS-CoV-2-Related Coronaviruses

Han GZ.

Abstract:

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Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

Naqvi AAT, Fatima K, Mohammad T, Fatima U, Singh IK, Singh A, Atif SM, Hariprasad G, Hasan GM, Hassan MI.

Abstract:

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Math and aftermath of COVID-19 pandemic and its interrelationship from the resilience perspective

Marko Ć, Andro K, Danijela Ć.

Abstract:

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Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold

Sun Z, Chen C, Li W, Martinez DR, Drelich A, Baek DS, Liu X, Mellors JW, Tseng CT, Baric RS, Dimitrov DS.

Abstract:

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COVID-19 and Antimicrobial Resistance: Parallel and Interacting Health Emergencies

Nieuwlaat R, Mbuagbaw L, Mertz D, Burrows L, Bowdish DME, Moja L, Wright GD, Schünemann HJ.

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Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and Immunity

Clapham H, Hay J, Routledge I, Takahashi S, Choisy M, Cummings D, Grenfell B, Metcalf CJE, Mina M, Barraquer IR, Salje H, Tam CC.

Abstract:

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An in silico approach for identification of novel inhibitors as potential therapeutics targeting COVID-19 main protease

Havranek B, Islam SM.

Abstract:

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Computational investigation on Andrographis paniculata phytochemicals to evaluate their potency against SARS-CoV-2 in comparison to known antiviral compounds in drug trials

Murugan NA, Pandian CJ, Jeyakanthan J.

Abstract:

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Development of a simple, interpretable and easily transferable QSAR model for quick screening antiviral databases in search of novel 3C-like protease (3CLpro) enzyme inhibitors against SARS-CoV diseases

Kumar V, Roy K.

Abstract:

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Community Susceptibility and Resiliency to COVID-19 Across the Rural-Urban Continuum in the United States

Peters DJ.

Abstract:

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Dysregulation of the immune response affects the outcome of critical COVID-19 patients

Wei LL, Wang WJ, Chen DX, Xu B.

Abstract:

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Evolutionary relationships and sequence-structure determinants in human SARS coronavirus-2 spike proteins for host receptor recognition

Guruprasad L.

Abstract:

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SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure

Thierry AR, Roch B.

Abstract:

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SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle East

Gong YN, Tsao KC, Hsiao MJ, Huang CG, Huang PN, Huang PW, Lee KM, Liu YC, Yang SL, Kuo RL, Chen KF, Liu YC, Huang SY, Huang HI, Liu MT, Yang JR, Chiu CH, Yang CT, Chen GW, Shih SR.

Abstract:

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Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site

Jin X, Xu K, Jiang P, Lian J, Hao S, Yao H, Jia H, Zhang Y, Zheng L, Zheng N, Chen D, Yao J, Hu J, Gao J, Wen L, Shen J, Ren Y, Yu G, Wang X, Lu Y, Yu X, Yu L, Xiang D, Wu N, Lu X, Cheng L, Liu F, Wu H, Jin C, Yang X, Qian P, Qiu Y, Sheng J, Liang T, Li L, Yang Y.

Abstract:

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Development of an automatic integrated gene detection system for novel Severe acute respiratory syndrome-related coronavirus (SARS-CoV 2)

Li Y, Li J, Zhang Y, Dai L, Li L, Liu J, Zhang S, Wu X, Hu Y, Qin C, Jiang T, Kang X.

Abstract:

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Per- and Polyfluoroalkyl Substances, Microplastics, and COVID-19: Will We Ever Learn?

Landis WG.

Abstract:

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An updated review of the association of host genetic factors with susceptibility and resistance to COVID-19

Mohammadpour S, Torshizi Esfahani A, Halaji M, Lak M, Ranjbar R.

Abstract:

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Coronavirus Disease 2019: A Comprehensive Review of Etiology, Pathogenesis, Diagnosis, and Ongoing Clinical Trials

Sarvepalli D.

Abstract:

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Guidelines for communicating about bats to prevent persecution in the time of COVID-19

MacFarlane D, Rocha R.

Abstract:

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Systemically comparing host immunity between survived and deceased COVID-19 patients

Wang F, Hou H, Yao Y, Wu S, Huang M, Ran X, Zhou H, Liu Z, Sun Z.

Abstract:

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Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR.

Abstract:

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Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

Brouwer PJM, Caniels TG, van der Straten K, Snitselaar JL, Aldon Y, Bangaru S, Torres JL, Okba NMA, Claireaux M, Kerster G, Bentlage AEH, van Haaren MM, Guerra D, Burger JA, Schermer EE, Verheul KD, van der Velde N, van der Kooi A, van Schooten J, van Breemen MJ, Bijl TPL, Sliepen K, Aartse A, Derking R, Bontjer I, Kootstra NA, Wiersinga WJ, Vidarsson G, Haagmans BL, Ward AB, de Bree GJ, Sanders RW, van Gils MJ.

Abstract:

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Response to the letter of L. Santacroce regarding article "Enhancing immunity in viral infections, with special emphasis on COVID-19: A review" (Jayawardena et al.)

Jayawardena R, Sooriyaarachchi P, Chourdakis M, Jeewandara C, Ranasinghe P.

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Molecular conservation and differential mutation on ORF3a gene in Indian SARS-CoV2 genomes

Hassan SS, Choudhury PP, Basu P, Jana SS.

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Elevated nucleoprotein-induced interferon-γ release in COVID-19 patients detected in a SARS-CoV-2 enzyme-linked immunosorbent spot assay

Thijsen S, Heron M, Gremmels H, van der Kieft R, Reusken C, Kremer K, Limonard G, Bossink A.

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Eltrombopag is a potential target for drug intervention in SARS-CoV-2 spike protein

Feng S, Luan X, Wang Y, Wang H, Zhang Z, Wang Y, Tian Z, Liu M, Xiao Y, Zhao Y, Zhou R, Zhang S.

Abstract:

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Anti-SARS-CoV-2 hyperimmune plasma workflow

Annamaria P, Eugenia Q, Paolo S.

Abstract:

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Response to "COVID-19: room for treating T cell exhaustion?"

Drewry AM, Hotchkiss R, Kulstad E.

Abstract:

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COVID-19 targets the right lung

Li J, Yu X, Hu S, Lin Z, Xiong N, Gao Y.

Abstract:

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Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

Pelaia C, Tinello C, Vatrella A, De Sarro G, Pelaia G.

Abstract:

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Fragment molecular orbital based interaction analyses on COVID-19 main protease - inhibitor N3 complex (PDB ID:6LU7)

Hatada R, Okuwaki K, Mochizuki Y, Handa Y, Fukuzawa K, Komeiji Y, Okiyama Y, Tanaka S.

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COVID-19 will further exacerbate global antimicrobial resistance

Yam ELY.

Abstract:

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Monoclonal Antibodies for Prevention and Treatment of COVID-19

Marovich M, Mascola JR, Cohen MS.

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Neurobiology of COVID-19

Fotuhi M, Mian A, Meysami S, Raji CA.

Abstract:

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Herd immunity or suppression strategy to combat COVID-19

Jung F, Krieger V, Hufert FT, Küpper JH.

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Repurposing cefuroxime for treatment of COVID-19: a scoping review of in silico studies

Durojaiye AB, Clarke JD, Stamatiades GA, Wang C.

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A Pathophysiological Perspective on COVID-19's Lethal Complication: From Viremia to Hypersensitivity Pneumonitis-like Immune Dysregulation

Sanchez-Gonzalez MA, Moskowitz D, Issuree PD, Yatzkan G, Rizvi SAA, Day K.

Abstract:

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EML webinar overview: Simulation-assisted discovery of membrane targeting nanomedicine

Zou G, Liu Y, Gao H.

Abstract:

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Short report on implications of Covid-19 and emerging zoonotic infectious diseases for pastoralists and Africa

Egeru A, Dejene SW, Siya A.

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IgY - turning the page toward passive immunization in COVID-19 infection (Review)

Constantin C, Neagu M, Diana Supeanu T, Chiurciu V, A Spandidos D.

Abstract:

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Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)

Kurth F, Roennefarth M, Thibeault C, Corman VM, Müller-Redetzky H, Mittermaier M, Ruwwe-Glösenkamp C, Heim KM, Krannich A, Zvorc S, Schmidt S, Kretzler L, Dang-Heine C, Rose M, Hummel M, Hocke A, Hübner RH, Opitz B, Mall MA, Röhmel J, Landmesser U, Pieske B, Knauss S, Endres M, Spranger J, Mockenhaupt FP, Tacke F, Treskatsch S, Angermair S, Siegmund B, Spies C, Weber-Carstens S, Eckardt KU, Schürmann D, Uhrig A, Stegemann MS, Zoller T, Drosten C, Suttorp N, Witzenrath M, Hippenstiel S, von

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Natural RNA dependent RNA polymerase inhibitors: Molecular docking studies of some biologically active alkaloids of Argemone mexicana

Pandeya KB, Ganeshpurkar A, Mishra MK.

Abstract:

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Detection of SARS-CoV-2 RNA in fecal specimens of patients with confirmed COVID-19: a meta-analysis

Wong MC, Huang J, Lai C, Ng R, Chan FKL, Chan PKS.

Abstract:

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Molecular mimicry may explain multi-organ damage in COVID-19

Angileri F, Legare S, Gammazza AM, de Macario EC, Macario AJL, Cappello F.

Abstract:

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Sequence homology between human PARP14 and the SARS-CoV-2 ADP ribose 1'-phosphatase

Thomas E, Saad R.

Abstract:

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Have deaths from COVID-19 in Europe plateaued due to herd immunity?

Okell LC, Verity R, Watson OJ, Mishra S, Walker P, Whittaker C, Katzourakis A, Donnelly CA, Riley S, Ghani AC, Gandy A, Flaxman S, Ferguson NM, Bhatt S.

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Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study

Stringhini S, Wisniak A, Piumatti G, Azman AS, Lauer SA, Baysson H, De Ridder D, Petrovic D, Schrempft S, Marcus K, Yerly S, Arm Vernez I, Keiser O, Hurst S, Posfay-Barbe KM, Trono D, Pittet D, Gétaz L, Chappuis F, Eckerle I, Vuilleumier N, Meyer B, Flahault A, Kaiser L, Guessous I.

Abstract:

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Potential of coronavirus 3C-like protease inhibitors for the development of new anti-SARS-CoV-2 drugs: Insights from structures of protease and inhibitors

He J, Hu L, Huang X, Wang C, Zhang Z, Wang Y, Zhang D, Ye W.

Abstract:

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COVID19 in South Asians/Asian Indians: Heterogeneity of Data and Implications for Pathophysiology and Research

Gupta R, Misra A.

Abstract:

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Disinfection of corona virus in histopathology laboratories

Luqman Z, Iqbal N, Ali HM, Mustafa Z, Sikandar A, Kausar R.

Abstract:

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Targeting the immunology of coronavirus disease-19: synchronization creates symphony

Ahmed S, Anirvan P.

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A versatile mouse model of COVID-19

Borrmann H, Rigby RE.

Abstract:

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MERS-CoV and SARS-CoV infections in animals: a systematic review and meta-analysis of prevalence studies

Bonilla-Aldana DK, Cardona-Trujillo MC, García-Barco A, Holguin-Rivera Y, Cortes-Bonilla I, Bedoya-Arias HA, Patiño-Cadavid LJ, Tamayo-Orozco JD, Paniz-Mondolfi A, Zambrano LI, Dhama K, Sah R, Rabaan AA, Balbin-Ramon GJ, Rodriguez-Morales AJ.

Abstract:

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Preparing for emerging respiratory pathogens such as SARS-CoV, MERS-CoV, and SARS-CoV-2

Al-Tawfiq JA, Garout MA, Gautret P.

Abstract:

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Part I. SARS-CoV-2 triggered 'PANIC' attack in severe COVID-19

Frohman EM, Villemarette-Pittman NR, Melamed E, Cruz RA, Longmuir R, Varkey TC, Steinman L, Zamvil SS, Frohman TC.

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Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)

Yuan S, Chan CC, Chik KK, Tsang JO, Liang R, Cao J, Tang K, Cai JP, Ye ZW, Yin F, To KK, Chu H, Jin DY, Hung IF, Yuen KY, Chan JF.

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[In Focus: SARS-CoV-2 and the COVID-19 Pandemic]

Giunta RE.

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COVID reverse transcriptase PCR in private laboratories: from theory to reality

Autissier M, Guiraud G, Lévy Y.

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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

Wrapp D, De Vlieger D, Corbett KS, Torres GM, Wang N, Van Breedam W, Roose K, van Schie L; VIB-CMB COVID-19 Response Team, Hoffmann M, Pöhlmann S, Graham BS, Callewaert N, Schepens B, Saelens X, McLellan JS.

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Role of the GTNGTKR motif in the N-terminal receptor-binding domain of the SARS-CoV-2 spike protein

Behloul N, Baha S, Shi R, Meng J.

Abstract:

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Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2

Peng Q, Peng R, Yuan B, Zhao J, Wang M, Wang X, Wang Q, Sun Y, Fan Z, Qi J, Gao GF, Shi Y.

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ACEi and ARB with COVID-19

Khashkhusha TR, Chan JSK, Harky A.

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Rapid detection of novel coronavirus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by reverse transcription-loop-mediated isothermal amplification

Lamb LE, Bartolone SN, Ward E, Chancellor MB.

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Neuropathological Features of Covid-19

Solomon IH, Normandin E, Bhattacharyya S, Mukerji SS, Keller K, Ali AS, Adams G, Hornick JL, Padera RF Jr, Sabeti P.

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SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists

Yuen CK, Lam JY, Wong WM, Mak LF, Wang X, Chu H, Cai JP, Jin DY, To KK, Chan JF, Yuen KY, Kok KH.

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Detection and Isolation of SARS-CoV-2 in Serum, Urine, and Stool Specimens of COVID-19 Patients from the Republic of Korea

Kim JM, Kim HM, Lee EJ, Jo HJ, Yoon Y, Lee NJ, Son J, Lee YJ, Kim MS, Lee YP, Chae SJ, Park KR, Cho SR, Park S, Kim SJ, Wang E, Woo S, Lim A, Park SJ, Jang J, Chung YS, Chin BS, Lee JS, Lim D, Han MG, Yoo CK.

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SARS-CoV-2 epidemic in India: epidemiological features and in silico analysis of the effect of interventions

Mazumder A, Arora M, Bharadiya V, Berry P, Agarwal M, Behera P, Shewade HD, Lohiya A, Gupta M, Rao A, Parameswaran GG.

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COVID-19 infection and oxidative stress: an under-explored approach for prevention and treatment?

Ntyonga-Pono MP.

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Leveraging polymerase chain reaction technique (GeneXpert) to upscaling testing capacity for SARS-CoV-2 (COVID-19) in Nigeria: a game changer

Oladimeji O, Atiba BP, Adeyinka DA.

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Ten recommendations for supporting open pathogen genomic analysis in public health

Black A, MacCannell DR, Sibley TR, Bedford T.

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Owner concerns that pets have Covid-19

Watson KM, Zhang Y, Towns K, Kahe K.

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Complete Genome Sequence of a Novel Coronavirus (SARS-CoV-2) Isolate from Bangladesh

Saha S, Malaker R, Sajib MSI, Hasanuzzaman M, Rahman H, Ahmed ZB, Islam MS, Islam M, Hooda Y, Ahyong V, Vanaerschot M, Batson J, Hao S, Kamm J, Kistler A, Tato CM, DeRisi JL, Saha SK.

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In Silico computational screening of Kabasura Kudineer - Official Siddha Formulation and JACOM against SARS-CoV-2 spike protein

Kiran G, Karthik L, Shree Devi MS, Sathiyarajeswaran P, Kanakavalli K, Kumar KM, Ramesh Kumar D.

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Immunoinformatics and Structural Analysis for Identification of Immunodominant Epitopes in SARS-CoV-2 as Potential Vaccine Targets

Mukherjee S, Tworowski D, Detroja R, Mukherjee SB, Frenkel-Morgenstern M.

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Could MEFV mutation carriage status have a protective role for COVID-19 pandemic?

Kavukçu S, Soylu A.

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SARS-Cov-2RNA found on particulate matter of Bergamo in Northern Italy: First evidence

Setti L, Passarini F, De Gennaro G, Barbieri P, Perrone MG, Borelli M, Palmisani J, Di Gilio A, Torboli V, Fontana F, Clemente L, Pallavicini A, Ruscio M, Piscitelli P, Miani A.

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What is the potential function of microRNAs as biomarkers and therapeutic targets in COVID-19?

Guterres A, de Azeredo Lima CH, Miranda RL, Gadelha MR.

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A plea for the pathogenic role of immune complexes in severe Covid-19

Vuitton DA, Vuitton L, Seillès E, Galanaud P.

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Antibody-dependent enhancement and COVID-19: Moving toward acquittal

Yager EJ.

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Evaluation of the EDI enzyme linked immunosorbent assays for the detection of SARS-CoV-2 IgM and IgG antibodies in human plasma

Bundschuh C, Egger M, Wiesinger K, Gabriel C, Clodi M, Mueller T, Dieplinger B.

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Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase

Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z.

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SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KH 3rd, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, Gralinski LE, Schäfer A, Dang H, Gilmore R, Nakano S, Sun L, Fulcher ML, Livraghi-Butrico A, Nicely NI, Cameron M, Cameron C, Kelvin DJ, de Silva A, Margolis DM, Markmann A, Bartelt L, Zumwalt R, Martinez FJ, Salvatore SP, Borczuk A, Tata PR, Sontake V, Kimple A, Jaspers I, O'Neal WK, Randell SH, Boucher RC, Baric RS.

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Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection

Isidori AM, Giannetta E, Pofi R, Venneri MA, Gianfrilli D, Campolo F, Mastroianni CM, Lenzi A, d'Ettorre G.

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First Reported Cases of SARS-CoV-2 Infection in Companion Animals - New York, March-April 2020

Newman A, Smith D, Ghai RR, Wallace RM, Torchetti MK, Loiacono C, Murrell LS, Carpenter A, Moroff S, Rooney JA, Barton Behravesh C.

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Targeting SARS-CoV-2: Novel Source of Antiviral Compound(s) against COVID-19?

Siddiqui R, Khan NA.

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Genetic gateways to COVID-19 infection: Implications for risk, severity, and outcomes

Debnath M, Banerjee M, Berk M.

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Effective block by pirfenidone, an antifibrotic pyridone compound (5-methyl-1-phenylpyridin-2[H-1]-one), on hyperpolarization-activated cation current: An additional but distinctive target

Chang WT, Ragazzi E, Liu PY, Wu SN.

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Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020

Walker A, Houwaart T, Wienemann T, Vasconcelos MK, Strelow D, Senff T, Hülse L, Adams O, Andree M, Hauka S, Feldt T, Jensen BE, Keitel V, Kindgen-Milles D, Timm J, Pfeffer K, Dilthey AT.

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Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

Gussow AB, Auslander N, Faure G, Wolf YI, Zhang F, Koonin EV.

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Comparative pathogenesis of bovine and porcine respiratory coronaviruses in the animal host species and SARS-CoV-2 in humans

Saif LJ, Jung K.

Abstract:

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CNS inflammatory vasculopathy with antimyelin oligodendrocyte glycoprotein antibodies in COVID-19

Pinto AA, Carroll LS, Nar V, Varatharaj A, Galea I.

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Genomics of COVID-19: molecular mechanisms going from susceptibility to severity of the disease

Mehrian-Shai R, Novelli G, Vasiliou V, Watt J, Reichardt JKV.

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COVID-19: viral-host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection

Messina F, Giombini E, Agrati C, Vairo F, Ascoli Bartoli T, Al Moghazi S, Piacentini M, Locatelli F, Kobinger G, Maeurer M, Zumla A, Capobianchi MR, Lauria FN, Ippolito G; COVID 19 INMI Network Medicine for IDs Study Group.

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Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine

Bonam SR, Muller S, Bayry J, Klionsky DJ.

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Evaluation of Chemical Protocols for Inactivating SARS-CoV-2 Infectious Samples

Pastorino B, Touret F, Gilles M, Luciani L, de Lamballerie X, Charrel RN.

Abstract:

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Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: Hope or Hype?

Brest P, Benzaquen J, Klionsky DJ, Hofman P, Mograbi B.

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ACE2 diversity in placental mammals reveals the evolutionary strategy of SARS-CoV-2

Bibiana S O F, Vargas-Pinilla P, Amorim CEG, Sortica VA, Bortolini MC.

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In silico evaluation of marine fish proteins as nutritional supplements for COVID-19 patients

Yao Y, Luo Z, Zhang X.

Abstract:

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Consideration of Pannexin 1 channels in COVID-19 pathology and treatment

Swayne LA, Johnstone SR, Ng CS, Sanchez-Arias JC, Good ME, Penuela S, Lohman AW, Wolpe AG, Laubach VE, Koval M, Isakson BE.

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Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

Weiss C, Carriere M, Fusco L, Capua I, Regla-Nava JA, Pasquali M, Scott JA, Vitale F, Unal MA, Mattevi C, Bedognetti D, Merkoçi A, Tasciotti E, Yilmazer A, Gogotsi Y, Stellacci F, Delogu LG.

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Synthesis, Spectroscopic Characterizations of Novel Norcantharimides, Their ADME Properties and Docking Studies Against COVID-19 M(pr)°

Özkan H, Adem Ş.

Abstract:

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Genomic search for COVID-19 severity clues

Abstract:

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Culture-based virus isolation to evaluate potential infectivity of clinical specimens tested for COVID-19

Huang CG, Lee KM, Hsiao MJ, Yang SL, Huang PN, Gong YN, Hsieh TH, Huang PW, Lin YJ, Liu YC, Tsao KC, Shih SR.

Abstract:

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Immunoinformatics-guided designing of epitope-based subunit vaccines against the SARS Coronavirus-2 (SARS-CoV-2)

Sarkar B, Ullah MA, Johora FT, Taniya MA, Araf Y.

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Disposition of Patients with COVID-19 Infection Whose Respiratory Specimens Remain SARS-CoV-2 PCR-Positive

Mermel LA.

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Histopathology of COVID-19 pneumonia in two non-oncological, non-hospitalised cases as a reliable diagnostic benchmark

Scendoni R, Marchesani F, Cannovo N, Fedeli P, Cingolani M.

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C3 polymorphisms represent an important immunological confounder on the spread and outcome of COVID-19

Dai X.

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Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients

Bosch-Barrera J, Martin-Castillo B, Buxó M, Brunet J, Encinar JA, Menendez JA.

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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

Williamson BN, Feldmann F, Schwarz B, Meade-White K, Porter DP, Schulz J, van Doremalen N, Leighton I, Yinda CK, Pérez-Pérez L, Okumura A, Lovaglio J, Hanley PW, Saturday G, Bosio CM, Anzick S, Barbian K, Cihlar T, Martens C, Scott DP, Munster VJ, de Wit E.

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Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection

Yip CC, Sridhar S, Cheng AK, Leung KH, Choi GK, Chen JH, Poon RW, Chan KH, Wu AK, Chan HS, Chau SK, Chung TW, To KK, Tsang OT, Hung IF, Cheng VC, Yuen KY, Chan JF.

Abstract:

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Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2

Jiang RD, Liu MQ, Chen Y, Shan C, Zhou YW, Shen XR, Li Q, Zhang L, Zhu Y, Si HR, Wang Q, Min J, Wang X, Zhang W, Li B, Zhang HJ, Baric RS, Zhou P, Yang XL, Shi ZL.

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Anti-A Isohemagglutinin titers and SARS-CoV2 neutralization: implications for children and convalescent plasma selection

Daniele F.

Abstract:

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[Source of the COVID-19 pandemic: ecology and genetics of coronaviruses (Betacoronavirus: Coronaviridae) SARS-CoV, SARS-CoV-2 (subgenus Sarbecovirus), and MERS-CoV (subgenus Merbecovirus).]

Lvov DK, Alkhovsky SV.

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The Microbiology of Coronaviruses

Zafar H.

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Mutations in SARS-CoV-2 viral RNA identified in Eastern India: Possible implications for the ongoing outbreak in India and impact on viral structure and host susceptibility

Maitra A, Sarkar MC, Raheja H, Biswas NK, Chakraborti S, Singh AK, Ghosh S, Sarkar S, Patra S, Mondal RK, Ghosh T, Chatterjee A, Banu H, Majumdar A, Chinnaswamy S, Srinivasan N, Dutta S, DAS S.

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Clonal haematopoiesis and COVID-19: A possible deadly liaison

Shivarov V, Ivanova M.

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Immune Responses to SARS-CoV, MERS-CoV and SARS-CoV-2

İnandıklıoğlu N, Akkoc T.

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A single-cell atlas of the peripheral immune response in patients with severe COVID-19

Wilk AJ, Rustagi A, Zhao NQ, Roque J, Martínez-Colón GJ, McKechnie JL, Ivison GT, Ranganath T, Vergara R, Hollis T, Simpson LJ, Grant P, Subramanian A, Rogers AJ, Blish CA.

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First antibody against COVID-19 spike protein enters phase I

Mullard A.

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Societal considerations in host genome testing for COVID-19

Milne R.

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Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

Agrati C, Sacchi A, Bordoni V, Cimini E, Notari S, Grassi G, Casetti R, Tartaglia E, Lalle E, D'Abramo A, Castilletti C, Marchioni L, Shi Y, Mariano A, Song JW, Zhang JY, Wang FS, Zhang C, Fimia GM, Capobianchi MR, Piacentini M, Antinori A, Nicastri E, Maeurer M, Zumla A, Ippolito G.

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The inhibition of IL-2/IL-2R gives rise to CD8(+) T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia

Shi H, Wang W, Yin J, Ouyang Y, Pang L, Feng Y, Qiao L, Guo X, Shi H, Jin R, Chen D.

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Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits

Ravichandran S, Coyle EM, Klenow L, Tang J, Grubbs G, Liu S, Wang T, Golding H, Khurana S.

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Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California

Deng X, Gu W, Federman S, du Plessis L, Pybus OG, Faria N, Wang C, Yu G, Bushnell B, Pan CY, Guevara H, Sotomayor-Gonzalez A, Zorn K, Gopez A, Servellita V, Hsu E, Miller S, Bedford T, Greninger AL, Roychoudhury P, Starita LM, Famulare M, Chu HY, Shendure J, Jerome KR, Anderson C, Gangavarapu K, Zeller M, Spencer E, Andersen KG, MacCannell D, Paden CR, Li Y, Zhang J, Tong S, Armstrong G, Morrow S, Willis M, Matyas BT, Mase S, Kasirye O, Park M, Masinde G, Chan C, Yu AT, Chai SJ, Villarino E, Bon

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Early Insights into Immune Responses during COVID-19

St John AL, Rathore APS.

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Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle

da Silva CSB, Thaler M, Tas A, Ogando NS, Bredenbeek PJ, Ninaber DK, Wang Y, Hiemstra PS, Snijder EJ, van Hemert MJ.

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SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

Costela-Ruiz VJ, Illescas-Montes R, Puerta-Puerta JM, Ruiz C, Melguizo-Rodríguez L.

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The biological characteristics of SARS-CoV-2 spike protein Pro330-Leu650

Su QD, Yi Y, Zou YN, Jia ZY, Qiu F, Wang F, Yin WJ, Zhou WT, Zhang S, Yu PC, Bi SL, Shen LP, Wu GZ.

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From Wuhan to COVID-19 Pandemic: An Up-to-Date Review of Its Pathogenesis, Potential Therapeutics, and Recent Advances

Zeouk I, Bekhti K, Lorenzo-Morales J.

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The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities

Arisan ED, Dart A, Grant GH, Arisan S, Cuhadaroglu S, Lange S, Uysal-Onganer P.

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COVID-19: Pathogenesis, Genetic Polymorphism, Clinical Features and Laboratory Findings

Öztürk R.

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Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site

Jaimes JA, Millet JK, Whittaker GR.

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Expression of angiotensin-converting enzyme 2 and proteases in COVID-19 patients: A potential role of cellular FURIN in the pathogenesis of SARS-CoV-2

Drak Alsibai K.

Abstract:

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Neutralizing antibodies mediate virus-immune pathology of COVID-19

Jacobs JJL.

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Rapid In-Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Using Povidone-Iodine Oral Antiseptic Rinse

Bidra AS, Pelletier JS, Westover JB, Frank S, Brown SM, Tessema B.

Abstract:

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Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19

Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari JP, Pang AP, Sugai C, Francisco EB, Pise A, Rodrigues H, Ryou M, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Aklin E, Ndhlovu L, Sacha JB.

Abstract:

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Neutrophil extracellular traps (NETs) as markers of disease severity in COVID-19

Zuo Y, Yalavarthi S, Shi H, Gockman K, Zuo M, Madison JA, Blair C, Weber A, Barnes BJ, Egeblad M, Woods RJ, Kanthi Y, Knight JS.

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COVID-19 Critical Illness Pathophysiology Driven by Diffuse Pulmonary Thrombi and Pulmonary Endothelial Dysfunction Responsive to Thrombolysis

Poor HD, Ventetuolo CE, Tolbert T, Chun G, Serrao G, Zeidman A, Dangayach NS, Olin J, Kohli-Seth R, Powell CA.

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The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature

LoPresti M, Beck DB, Duggal P, Cummings DAT, Solomon BD.

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ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19

Emilsson V, Gudmundsson EF, Aspelund T, Jonsson BG, Gudjonsson A, Launer LJ, Lamb JR, Gudmundsdottir V, Jennings LL, Gudnason V.

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ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19

Pinto BG, Oliveira AE, Singh Y, Jimenez L, Goncalves AN, Ogava RL, Creighton R, Peron JP, Nakaya HI.

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A High Through-put Assay for Circulating Antibodies Directed against the S Protein of Severe Acute Respiratory Syndrome Corona virus 2

Weiss S, Klingler J, Hioe C, Amanat F, Baine I, Kojic EM, Stoever J, Liu S, Jurczyszak D, Bermudez-Gonzalez M, Simon V, Krammer F, Zolla-Pazner S.

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Intervention Serology and Interaction Substitution: Modeling the Role of 'Shield Immunity' in Reducing COVID-19 Epidemic Spread

Weitz JS, Beckett SJ, Coenen AR, Demory D, Dominguez-Mirazo M, Dushoff J, Leung CY, Li G, Magalie A, Park SW, Rodriguez-Gonzalez R, Shivam S, Zhao C.

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An 81 base-pair deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020)

Holland LA, Kaelin EA, Maqsood R, Estifanos B, Wu LI, Varsani A, Halden RU, Hogue BG, Scotch M, Lim ES.

Abstract:

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Clinical and Genetic Characteristics of Covid-19 Patients from UK Biobank

Kolin DA, Kulm S, Elemento O.

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Sequencing identifies multiple, early introductions of SARS-CoV2 to New York City Region

Maurano MT, Ramaswami S, Westby G, Zappile P, Dimartino D, Shen G, Feng X, Ribeiro-Dos-Santos AM, Vulpescu NA, Black M, Hogan M, Marier C, Meyn P, Zhang Y, Cadley J, Ordonez R, Luther R, Huang E, Guzman E, Serrano A, Belovarac B, Gindin T, Lytle A, Pinnell J, Vougiouklakis T, Boytard L, Chen J, Lin LH, Rapkiewicz A, Raabe V, Samanovic-Golden MI, Jour G, Osman I, Aguero-Rosenfeld M, Mulligan MJ, Cotzia P, Snuderl M, Heguy A.

Abstract:

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A Genomic Survey of SARS-CoV-2 Reveals Multiple Introductions into Northern California without a Predominant Lineage

Deng X, Gu W, Federman S, Du Plessis L, Pybus O, Faria N, Wang C, Yu G, Pan CY, Guevara H, Sotomayor-Gonzalez A, Zorn K, Gopez A, Servellita V, Hsu E, Miller S, Bedford T, Greninger A, Roychoudhury P, Famulare M, Chu HY, Shendure J, Starita L, Anderson C, Gangavarapu K, Zeller M, Spencer E, Andersen K, MacCannell D, Tong S, Armstrong G, Paden C, Li Y, Zhang Y, Morrow S, Willis M, Matyas B, Mase S, Kasirye O, Park M, Chan C, Yu A, Chai S, Villarino E, Bonin B, Wadford D, Chiu CY.

Abstract:

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Differential Redistribution of Activated Monocyte and Dendritic Cell Subsets to the Lung Associates with Severity of COVID-19

Sanchez-Cerrillo I, Landete P, Aldave B, Sanchez-Alonso S, Sanchez-Azofra A, Marcos-Jimenez A, Avalos E, Alcaraz-Serna A, de Los Santos I, Mateu-Albero T, Esparcia L, Lopez-Sanz C, Martinez-Fleta P, Gabrie L, Del Campo Guerola L, Calzada MJ, Gonzalez-Alvaro I, Alfranca A, Sanchez-Madrid F, Munoz-Calleja C, Soriano JB, Ancochea J, Martin-Gayo E.

Abstract:

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A Unique Clade of SARS-CoV-2 Viruses is Associated with Lower Viral Loads in Patient Upper Airways

Lorenzo-Redondo R, Nam HH, Roberts SC, Simons LM, Jennings LJ, Qi C, Achenbach CJ, Hauser AR, Ison MG, Hultquist JF, Ozer EA.

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Cross-sectional IgM and IgG profiles in SARS-CoV-2 infection

Ozturk T, Howell C, Benameur K, Ramonell RP, Cashman K, Pirmohammed S, Bassit L, Roback J, Marconi VC, Schinazi RF, Wharton W, Lee FE, Hu WT.

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Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2

Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Calfee CS, Castaneda G, DeRisi JL, Detweiler AM, Hao S, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Christenson SA, Kistler A, Langelier C.

Abstract:

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Single-cell Transcriptome Analysis Indicates New Potential Regulation Mechanism of ACE2 and NPs signaling among heart failure patients infected with SARS-CoV-2

Xu D, Ma M, Xu Y, Su Y, Ong SB, Hu X, Chai M, Zhao M, Li H, Chen Y, Xu X.

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Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients

Burbelo PD, Riedo FX, Morishima C, Rawlings S, Smith D, Das S, Strich JR, Chertow DS, Davey RT Jr, Cohen JI.

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Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays

Esposito D, Mehalko J, Drew M, Snead K, Wall V, Taylor T, Frank P, Denson JP, Hong M, Gulten G, Sadtler K, Messing S, Gillette W.

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Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2

Arizti-Sanz J, Freije CA, Stanton AC, Boehm CK, Petros BA, Siddiqui S, Shaw BM, Adams G, Kosoko-Thoroddsen TF, Kemball ME, Gross R, Wronka L, Caviness K, Hensley LE, Bergman NH, MacInnis BL, Lemieux JE, Sabeti PC, Myhrvold C.

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The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase enzyme

Alhammad YMO, Kashipathy MM, Roy A, Johnson DK, McDonald P, Battaile KP, Gao P, Lovell S, Fehr AR.

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Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK.

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Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, Martinez DR, Schäfer A, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE.

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The heterogeneous landscape and early evolution of pathogen-associated CpG and UpA dinucleotides in SARS-CoV-2

di Gioacchino A, Šulc P, Komarova AV, Greenbaum BD, Monasson R, Cocco S.

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A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures

Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, Glenn JS, Gralinski LE, Sheahan TP, Baric RS.

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Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

Han Y, Yang L, Duan X, Duan F, Nilsson-Payant BE, Yaron TM, Wang P, Tang X, Zhang T, Zhao Z, Bram Y, Redmond D, Houghton S, Nguyen D, Xu D, Wang X, Uhl S, Huang Y, Johnson JL, Xiang J, Wang H, Pan FC, Cantley LC, tenOever BR, Ho DD, Evans T, Schwartz RE, Chen HJ, Chen S.

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Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection

Sharma A, Garcia G, Arumugaswami V, Svendsen CN.

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Transcriptional profiling reveals TRPM5-expressing cells involved in viral infection in the olfactory epithelium

Baxter BD, Larson ED, Feinstein P, Polese AG, Bubak AN, Niemeyer CS, Merle L, Shepherd D, Ramakrishnan VR, Nagel MA, Restrepo D.

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Methods of inactivation of SARS-CoV-2 for downstream biological assays

Patterson EI, Prince T, Anderson ER, Casas-Sanchez A, Smith SL, Cansado-Utrilla C, Turtle L, Hughes GL.

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SARS-CoV2 (COVID-19) Structural/Evolution Dynamicome: Insights into functional evolution and human genomics

Gupta R, Charron J, Stenger CL, Painter J, Steward H, Cook TW, Faber W, Frisch A, Lind E, Bauss J, Li X, Sirpilla O, Soehnlen X, Underwood A, Hinds D, Morris M, Lamb N, Carcillo JA, Bupp C, Uhal BD, Rajasekaran S, Prokop JW.

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IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity

Ejemel M, Li Q, Hou S, Schiller ZA, Wallace AL, Amcheslavsky A, Yilmaz NK, Toomey JR, Schneider R, Close BJ, Chen DY, Conway HL, Mohsan S, Cavacini LA, Klempner MS, Schiffer CA, Wang Y.

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In-Vivo Toxicity Studies and In-Vitro Inactivation of SARS-CoV-2 by Povidone-iodine In-situ Gel Forming Formulations

Liang B, Yuan X, Wei G, Wang W, Zhang M, Peng H, Javer A, Mendenhall M, Julander J, Huang S, Michail H, Lu Y, Zhu Q, Baldwin J.

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