Vírus, Imunologia e Patogénese


Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells

Xiong HL, Wu YT, Cao JL, Yang R, Liu YX, Ma J, Qiao XY, Yao XY, Zhang BH, Zhang YL, Hou WH, Shi Y, Xu JJ, Zhang L, Wang SJ, Fu BR, Yang T, Ge SX, Zhang J, Yuan Q, Huang BY, Li ZY, Zhang TY, Xia NS.

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Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis

De Maio F, Lo Cascio E, Babini G, Sali M, Della Longa S, Tilocca B, Roncada P, Arcovito A, Sanguinetti M, Scambia G, Urbani A.

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Potential Role of Acacia Senegal (Gum Arabic) as Immunomodulatory Agent among newly diagnosed COVID 19 Patients: A structured summary of a protocol for a randomised, controlled, clinical trial

Kaddam L, Babiker R, Ali S, Satti S, Ali N, Elamin M, Mukhtar M, Elnimeiri M, Saeed A.

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Propolis and its potential against SARS-CoV-2 infection mechanisms and COVID-19 disease: Running title: Propolis against SARS-CoV-2 infection and COVID-19

Berretta AA, Silveira MAD, Cóndor Capcha JM, De Jong D.

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Evolutionary dynamics of the SARS-CoV-2 ORF8 accessory gene

Pereira F.

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Inferring the genetic variability in Indian SARS-CoV-2 genomes using consensus of multiple sequence alignment techniques

Saha I, Ghosh N, Maity D, Sharma N, Mitra K.

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Conserved HLA binding peptides from five non-structural proteins of SARS-CoV-2-An in silico glance

Marchan J.

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Cell and animal models of SARS-CoV-2 pathogenesis and immunity

Leist SR, Schäfer A, Martinez DR.

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Mycogenic Metal Nanoparticles for the Treatment of Mycobacterioses

Simões MF, Ottoni CA, Antunes A.

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Predicted peptide patterns from the SARS-CoV-2 proteome for MS-MS based diagnosis

Kapoor S, Subba P.

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Genomic evolution of severe acute respiratory syndrome Coronavirus 2 in India and vaccine impact

Jacob JJ, Vasudevan K, Veeraraghavan B, Iyadurai R, Gunasekaran K.

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A protein interaction map identifies existing drugs targeting SARS-CoV-2

Cava C, Bertoli G, Castiglioni I.

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Natural Killer Cell Dysfunction and Its Role in COVID-19

van Eeden C, Khan L, Osman MS, Cohen Tervaert JW.

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Natural Flavonoids as Potential Angiotensin-Converting Enzyme 2 Inhibitors for Anti-SARS-CoV-2

Muchtaridi M, Fauzi M, Khairul Ikram NK, Mohd Gazzali A, Wahab HA.

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Computational and Transcriptome Analyses Revealed Preferential Induction of Chemotaxis and Lipid Synthesis by SARS-CoV-2

Shaath H, Alajez NM.

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Genome based evolutionary lineage of SARS-CoV-2 towards the development of novel chimeric vaccine

Akhand MRN, Azim KF, Hoque SF, Moli MA, Joy BD, Akter H, Afif IK, Ahmed N, Hasan M.

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Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome

Gómez J, Albaiceta GM, García-Clemente M, López-Larrea C, Amado-Rodríguez L, Lopez-Alonso I, Hermida T, Enriquez AI, Herrero P, Melón S, Alvarez-Argüelles ME, Boga JA, Rojo-Alba S, Cuesta-Llavona E, Alvarez V, Lorca R, Coto E.

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Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight

Khan MI, Khan ZA, Baig MH, Ahmad I, Farouk AE, Song YG, Dong JJ.

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Global Initiative Seeks to Crack the COVID-19 Genetic Code

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COVID‐19 und Immunregulation – von grundlegenden und translationalen Aspekten zu klinischen Implikationen

Schön MP, Berking C, Biedermann T, Buhl T, Erpenbeck L, Eyerich K, Eyerich S, Ghoreschi K, Goebeler M, Ludwig RJ, Schäkel K, Schilling B, Schlapbach C, Stary G, von Stebut E, Steinbrink K.

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Systemische Immunsuppression in Zeiten von COVID‐19: Müssen wir umdenken?

Grabbe S, Beissert S, Enk A.

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A novel concept for treatment and vaccination against Covid-19 with an inhaled chitosan-coated DNA vaccine encoding a secreted spike protein portion

Tatlow D, Tatlow C, Tatlow S, Tatlow S.

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Telomere length, epidemiology, and pathogenesis of severe COVID-19

Tsilingiris D, Tentolouris A, Eleftheriadou I, Tentolouris N.

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Molecular dynamics study with mutation shows that N-terminal domain (NTD) structural re-orientation in NPC1 is required for proper alignment of cholesterol transport

Yoon H, Jeong H, Lee HH, Jang S.

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Transcriptomic analyses suggest that mucopolysaccharidosis patients may be less susceptible to COVID-19

Pierzynowska K, Gaffke L, Wƒôgrzyn G.

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Warriors, Worriers, and COVID-19: An Exploratory Study of the Catechol O-Methyltransferase Val158Met Polymorphism Across Populations

Rajkumar RP.

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Mutation density changes in SARS-CoV-2 are related to the pandemic stage but to a lesser extent in the dominant strain with mutations in spike and RdRp

Eskier D, Suner A, Karakülah G, Oktay Y.

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Expansion of atypical memory B cells is a prominent feature of COVID-19

Oliviero B, Varchetta S, Mele D, Mantovani S, Cerino A, Perotti CG, Ludovisi S, Mondelli MU.

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Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19

Chen X, Pan Z, Yue S, Yu F, Zhang J, Yang Y, Li R, Liu B, Yang X, Gao L, Li Z, Lin Y, Huang Q, Xu L, Tang J, Hu L, Zhao J, Liu P, Zhang G, Chen Y, Deng K, Ye L.

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Potential pathogenesis of severe acute respiratory syndrome coronavirus 2

Wu T, Zhang H, Hu E, Ma J.

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Immunotherapeutic approaches to curtail COVID-19

Owji H, Negahdaripour M, Hajighahramani N.

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Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, L

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Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication

Klann K, Bojkova D, Tascher G, Ciesek S, Münch C, Cinatl J.

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Potential use of noncoding RNAs and innovative therapeutic strategies to target the 5'UTR of SARS-CoV-2

Baldassarre A, Paolini A, Bruno SP, Felli C, Tozzi AE, Masotti A.

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In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors

Gurung AB.

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Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches

Alamri MA, Tahir Ul Qamar M, Mirza MU, Alqahtani SM, Froeyen M, Chen LL.

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Difference in levels of SARS-CoV-2 S1 and S2 subunits- and nucleocapsid protein-reactive SIgM/IgM, IgG and SIgA/IgA antibodies in human milk

Demers-Mathieu V, Dung M, Mathijssen GB, Sela DA, Seppo A, Järvinen KM, Medo E.

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Gene of the month: TMPRSS2 (transmembrane serine protease 2)

Thunders M, Delahunt B.

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Immunocytometric analysis of COVID patients: A contribution to personalized therapy?

Cacciapuoti S, De Rosa A, Gelzo M, Megna M, Raia M, Pinchera B, Pontarelli A, Scotto R, Scala E, Scarano F, Scalia G, Castaldo G, Fabbrocini G, Gentile I, Parrella R.

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Potential of Plant Proteins Digested In Silico by Gastrointestinal Enzymes as Nutritional Supplement for COVID-19 Patients

Luo Z, Su K, Zhang X.

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Understanding the Immunologic Characteristics of Neurologic Manifestations of SARS-CoV-2 and Potential Immunological Mechanisms

Mohammadi S, Moosaie F, Aarabi MH.

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Genomic surveillance revealed prevalence of unique SARS-CoV-2 variants bearing mutation in the RdRp gene among Nevada patients

Hartley P, Tillett RL, Xu Y, AuCoin DP, Sevinsky JR, Gorzalski A, Pandori MC, Buttery E, Hansen H, Picker M, Rossetto CC, Verma SC.

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Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion

Flower TG, Buffalo CZ, Hooy RM, Allaire M, Ren X, Hurley JH.

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Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies

Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP, Bjorkman PJ.

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Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

Wei J, Alfajaro MM, Hanna RE, DeWeirdt PC, Strine MS, Lu-Culligan WJ, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Gasque V, de Miguel F, Chen H, Oguntuyo K, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach B, Politi K, van Dijk D, Simon MD, Yan Q, Doench JG, Wilen CB.

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SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution

Siqueira JD, Goes LR, Alves BM, de Carvalho PS, Cicala C, Arthos J, Viola JPB, de Melo AC, Soares MA.

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Theoretical basis for stabilizing messenger RNA through secondary structure design

Wayment-Steele HK, Kim DS, Choe CA, Nicol JJ, Wellington-Oguri R, Sperberg RAP, Huang PS, Das R.

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Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

Johnson BA, Xie X, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Swetnam D, Plante JA, Aguilar P, Plante KS, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Shi PY, Freiberg AN, Menachery VD.

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Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2

Ghahremanpour MM, Tirado-Rives J, Deshmukh M, Ippolito JA, Zhang CH, de Vaca IC, Liosi ME, Anderson KS, Jorgensen WL.

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Structure-Altering Mutations of the SARS-CoV-2 Frame Shifting RNA Element

Schlick T, Zhu Q, Jain S, Yan S.

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Potential clinical drugs as covalent inhibitors of the priming proteases of the spike protein of SARS-CoV-2

Li Q, Wang Z, Zheng Q, Liu S.

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Exploring optical spectroscopic techniques and nanomaterials for virus detection

Lebohang Manoto S, El-Hussein A, Malabi R, Thobakgale L, Ombinda-Lemboumba S, Attia YA, Kasem MA, Mthunzi-Kufa P.

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Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: their in silico assessment as potential ligands for N-protein of SARS-CoV-2

Shahinshavali S, Hossain KA, Kumar AVDN, Reddy AG, Kolli D, Nakhi A, Rao MVB, Pal M.

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New insights into the cell- and tissue-specificity of glucocorticoid actions

Quatrini L, Ugolini S.

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Signal amplification by reversible exchange for COVID-19 antiviral drug candidates

Jeong HJ, Min S, Chae H, Kim S, Lee G, Namgoong SK, Jeong K.

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Immune characteristics of severe and critical COVID-19 patients

Yang L, Gou J, Gao J, Huang L, Zhu Z, Ji S, Liu H, Xing L, Yao M, Zhang Y.

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Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1

Benedetti F, Snyder GA, Giovanetti M, Angeletti S, Gallo RC, Ciccozzi M, Zella D.

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COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells

Latini A, Agolini E, Novelli A, Borgiani P, Giannini R, Gravina P, Smarrazzo A, Dauri M, Andreoni M, Rogliani P, Bernardini S, Helmer-Citterich M, Biancolella M, Novelli G.

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Coronavirus discovery by metagenomic sequencing: a tool for pandemic preparedness

Carbo EC, Sidorov IA, Zevenhoven-Dobbe JC, Snijder EJ, Claas EC, Laros JFJ, Kroes ACM, de Vries JJC.

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Interferon gamma, TGF-β1 and RANTES expression in upper airway samples from SARS-CoV-2 infected patients

Montalvo Villalba MC, Valdés Ramírez O, Muné Jiménez M, Arencibia Garcia A, Martinez Alfonso J, González Baéz G, Roque Arrieta R, Rosell Simón D, Alvárez Gainza D, Sierra Vázquez B, Resik Aguirre S, Guzmán Tirado MG.

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Scaffold morphing of arbidol (umifenovir) in search of multi-targeting therapy halting the interaction of SARS-CoV-2 with ACE2 and other proteases involved in COVID-19

Choudhary S, Silakari O.

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The Pathology of Severe COVID-19-Related Lung Damage

Kommoss FKF, Schwab C, Tavernar L, Schreck J, Wagner WL, Merle U, Jonigk D, Schirmacher P, Longerich T.

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The phenotypic changes of γδ T cells in COVID-19 patients

Lei L, Qian H, Yang X, Zhang X, Zhang D, Dai T, Guo R, Shi L, Cheng Y, Zhang B, Zhou X, Hu J, Guo Y.

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Development and effectiveness of Pseudotyped SARS-CoV-2 system as determined by neutralizing efficiency and entry inhibition test in vitro

Yang R, Huang B, Ruhan A, Li W, Wang W, Deng Y, Tan W.

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Dataset of mutational analysis, miRNAs targeting SARS-CoV-2 genes and host gene expression in SARS-CoV and SARS-CoV-2 infections

Sardar R, Satish D, Birla S, Gupta D.

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Adenovirus and novel coronavirus (SARS-Cov2) coinfection: A case report

Motta JC, Gómez CC.

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Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia

Kam YW, Ahmed MY, Amrun SN, Lee B, Refaie T, Elgizouli K, Fong SW, Renia L, Ng LF.

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Molecular dynamics simulation of docking structures of SARS-CoV-2 main protease and HIV protease inhibitors

Cardoso WB, Mendanha SA.

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Nigella sativa L as a potential phytotherapy for coronavirus disease 2019: A mini review of in silico studies

Koshak DAE, Koshak PEA.

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Expression profiling meta-analysis of ACE2 and TMPRSS2, the putative anti-inflammatory receptor and priming protease of SARS-CoV-2 in human cells, and identification of putative modulators

Gkogkou E, Barnasas G, Vougas K, Trougakos IP.

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Modeling Potential Autophagy Pathways in COVID-19 and Sarcoidosis

Calender A, Israel-Biet D, Valeyre D, Pacheco Y.

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Is Immunological Memory a Burden in Times of COVID-19?

Ortega E.

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BCG vaccine may generate cross-reactive T cells against SARS-CoV-2: In silico analyses and a hypothesis

Tomita Y, Sato R, Ikeda T, Sakagami T.

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Monocyte activation in systemic Covid-19 infection: Assay and rationale

Martinez FO, Combes TW, Orsenigo F, Gordon S.

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Sunlight ultraviolet radiation dose is negatively correlated with the percent positive of SARS-CoV-2 and four other common human coronaviruses in the U.S

Tang L, Liu M, Ren B, Wu Z, Yu X, Peng C, Tian J.

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Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity

Han M, Xu M, Zhang Y, Liu Z, Li S, He T, Li J, Gao Y, Liu W, Li T, Chen Z, Huang X, Cheng G, Wang J, Dittmer U, Witzke O, Zou G, Li X, Lu M, Zhang Z.

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Optimization Rules for SARS-CoV-2 M(pro) Antivirals: Ensemble Docking and Exploration of the Coronavirus Protease Active Site

Stoddard SV, Stoddard SD, Oelkers BK, Fitts K, Whalum K, Whalum K, Hemphill AD, Manikonda J, Martinez LM, Riley EG, Roof CM, Sarwar N, Thomas DM, Ulmer E, Wallace FE, Pandey P, Roy S.

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Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis

Rueca M, Bartolini B, Gruber CEM, Piralla A, Baldanti F, Giombini E, Messina F, Marchioni L, Ippolito G, Di Caro A, Capobianchi MR.

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Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium

Chow JT, Salmena L.

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A survey of genetic variants in SARS-CoV-2 interacting domains of ACE2, TMPRSS2 and TLR3/7/8 across populations

Lee IH, Lee JW, Kong SW.

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Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020

Hu WT, Howell JC, Ozturk T, Benameur K, Bassit LC, Ramonell R, Cashman KS, Pirmohammed S, Roback JD, Marconi VC, Yang I, Mac VV, Smith D, Sanz I, Wharton W, Lee FE, Schinazi RF.

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The receptor binding domain of SARS-CoV-2 spike protein is the result of an ancestral recombination between the bat-CoV RaTG13 and the pangolin-CoV MP789

Flores-Alanis A, Sandner-Miranda L, Delgado G, Cravioto A, Morales-Espinosa R.

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Characterization of accessory genes in coronavirus genomes

Michel CJ, Mayer C, Poch O, Thompson JD.

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Targeting the sAC-Dependent cAMP Pool to Prevent SARS-Cov-2 Infection

Aslam M, Ladilov Y.

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Clinical, immunological and virological characterization of COVID-19 patients that test re-positive for SARS-CoV-2 by RT-PCR

Lu J, Peng J, Xiong Q, Liu Z, Lin H, Tan X, Kang M, Yuan R, Zeng L, Zhou P, Liang C, Yi L, du Plessis L, Song T, Ma W, Sun J, Pybus OG, Ke C.

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Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2

Tripathi PK, Upadhyay S, Singh M, Raghavendhar S, Bhardwaj M, Sharma P, Patel AK.

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Characterizing COVID-19 severity, epidemiology and SARS-CoV-2 genotypes in a regional business hub of China

Yan Y, Liu B, Ding H, Wang X, Dai Y, Ding D, Yu H, Sha M, Lui C, Chantsalmaa D, Qiu Y, Huang L, Hu Q.

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Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting

Robson F, Khan KS, Le TK, Paris C, Demirbag S, Barfuss P, Rocchi P, Ng WL.

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Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice

Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, Perlman H, Ridge KM, Sznajder JI, Sporn PHS, Chandel NS, Yu J, Fu X, Petrache I, Tuder R, Budinger GRS, Liu J.

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Molecular Pathogenesis, Immunopathogenesis and Novel Therapeutic Strategy Against COVID-19

Chatterjee SK, Saha S, Munoz MNM.

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Insights Into Dynamics of Inhibitor and Ubiquitin-Like Protein Binding in SARS-CoV-2 Papain-Like Protease

Bosken YK, Cholko T, Lou YC, Wu KP, Chang CA.

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Plants Metabolites: Possibility of Natural Therapeutics Against the COVID-19 Pandemic

Bhuiyan FR, Howlader S, Raihan T, Hasan M.

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Single Virus Targeting Multiple Organs: What We Know and Where We Are Heading?

Prasad A, Prasad M.

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Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System

Xu R, Shi M, Li J, Song P, Li N.

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Functional Pangenome Analysis Shows Key Features of E Protein Are Preserved in SARS and SARS-CoV-2

Alam I, Kamau AA, Kulmanov M, Jaremko Ł, Arold ST, Pain A, Gojobori T, Duarte CM.

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Genetic Analysis of the Coronavirus SARS-CoV-2 Host Protease TMPRSS2 in Different Populations

Russo R, Andolfo I, Lasorsa VA, Iolascon A, Capasso M.

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Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets

Fecchi K, Anticoli S, Peruzzu D, Iessi E, Gagliardi MC, Matarrese P, Ruggieri A.

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Cellular and Molecular Pathways of COVID-19 and Potential Points of Therapeutic Intervention

Hussman JP.

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Dynamics of the ACE2-SARS-CoV-2/SARS-CoV spike protein interface reveal unique mechanisms

Ali A, Vijayan R.

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Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations

Pehote G, Vij N.

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Biomedical application, Drug Delivery and Metabolic Pathway of Antiviral Nanotherapeutics for combating viral Pandemic: A Review

Mukherjee S, Mazumder P, Joshi M, Joshi C, Dalvi SV, Kumar M.

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Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020

Manickam C, Sugawara S, Reeves RK.

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Pooling Upper Respiratory Specimens for Rapid Mass Screening of COVID-19 by Real-Time RT-PCR

Kim SY, Lee J, Sung H, Lee H, Han MG, Yoo CK, Lee SW, Hong KH.

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Human post-infection serological response to the spike and nucleocapsid proteins of SARS-CoV-2

Xiao C, Ling S, Qiu M, Deng Z, Chen L, Zhu A, Chen Y, Liu Y, Lin X, Lin F, Wu Q, Shen L, Ye F, Liu X, Li Y, Zhao J, Yang Z, Cowling BJ, Webby R, Zanin M, Wong SS.

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Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study

Hanley B, Naresh KN, Roufosse C, Nicholson AG, Weir J, Cooke GS, Thursz M, Manousou P, Corbett R, Goldin R, Al-Sarraj S, Abdolrasouli A, Swann OC, Baillon L, Penn R, Barclay WS, Viola P, Osborn M.

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In Silico Identification of Potential Natural Product Inhibitors of Human Proteases Key to SARS-CoV-2 Infection

Vivek-Ananth RP, Rana A, Rajan N, Biswal HS, Samal A.

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Drug Repurposing for Candidate SARS-CoV-2 Main Protease Inhibitors by a Novel In Silico Method

Sencanski M, Perovic V, Pajovic SB, Adzic M, Paessler S, Glisic S.

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Viral Vectors Applied for RNAi-Based Antiviral Therapy

Lundstrom K.

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Viroinformatics approach to explore the inhibitory mechanism of existing drugs repurposed to fight against COVID-19

Bibi N, Gul S, Ali J, Kamal MA.

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Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L.

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Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

Golden JW, Cline CR, Zeng X, Garrison AR, Carey BD, Mucker EM, White LE, Shamblin JD, Brocato RL, Liu J, Babka AM, Rauch HB, Smith JM, Hollidge BS, Fitzpatrick C, Badger CV, Hooper JW.

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Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals

Gong F, Dai Y, Zheng T, Cheng L, Zhao D, Wang H, Liu M, Pei H, Jin T, Yu D, Zhou P.

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SARS-CoV-2 Antibody Responses Correlate with Resolution of RNAemia But Are Short-Lived in Patients with Mild Illness

Röltgen K, Wirz OF, Stevens BA, Powell AE, Hogan CA, Najeeb J, Hunter M, Sahoo MK, Huang C, Yamamoto F, Manalac J, Otrelo-Cardoso AR, Pham TD, Rustagi A, Rogers AJ, Shah NH, Blish CA, Cochran JR, Nadeau KC, Jardetzky TS, Zehnder JL, Wang TT, Kim PS, Gombar S, Tibshirani R, Pinsky BA, Boyd SD.

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Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity

Martino C, Kellman BP, Sandoval DR, Clausen TM, Marotz CA, Song SJ, Wandro S, Zaramela LS, Salido Benítez RA, Zhu Q, Armingol E, Vázquez-Baeza Y, McDonald D, Sorrentino JT, Taylor B, Belda-Ferre P, Liang C, Zhang Y, Schifanella L, Klatt NR, Havulinna AS, Jousilahti P, Huang S, Haiminen N, Parida L, Kim HC, Swafford AD, Zengler K, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Esko JD, Lewis NE, Knight R.

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Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

Chen CZ, Xu M, Pradhan M, Gorshkov K, Petersen J, Straus MR, Zhu W, Shinn P, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zimmerberg J, Zheng W, Whittaker GR.

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SARS-CoV-2 infection dynamics in lungs of African green monkeys

Speranza E, Williamson BN, Feldmann F, Sturdevant GL, Pérez-Pérez L, Mead-White K, Smith BJ, Lovaglio J, Martens C, Munster VJ, Okumura A, Shaia C, Feldmann H, Best SM, de Wit E.

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SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells

Dominguez Andres A, Feng Y, Campos AR, Yin J, Yang CC, James B, Murad R, Kim H, Deshpande AJ, Gordon DE, Krogan N, Pippa R, Ronai ZA.

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SARS-CoV-2-specific T cells exhibit phenotypic features of robust helper function, lack of terminal differentiation, and high proliferative potential

Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR.

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Host immune response driving SARS-CoV-2 evolution

Wang R, Hozumi Y, Zheng YH, Yin C, Wei GW.

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Investigating the potential antiviral activity drugs against SARS-CoV-2 by molecular docking simulation

El-Hoshoudy AN.

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Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients

Recalde B, García-Tobar L, Argueta A, Álvarez L, De Andrea CE, Fernández Alonso M, Ezponda A, Carmona Torre F, Jordán Iborra C, Quiroga JA, Del Pozo JL, Zulueta JJ, Echarri G, Landecho MF, Lozano MD.

Abstract:

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Inactivation analysis of SARS-CoV-2 by specimen transport media, nucleic acid extraction reagents, detergents and fixatives

Welch SR, Davies KA, Buczkowski H, Hettiarachchi N, Green N, Arnold U, Jones M, Hannah MJ, Evans R, Burton C, Burton JE, Guiver M, Cane PA, Woodford N, Bruce CB, Roberts ADG, Killip MJ.

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Glial Cells: insights and perspectives

Vargas G, Medeiros Geraldo LH, Salom√£o N, Paes MV, Souza Lima FR, Alcantara Gomes FC.

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Structure-based virtual screening of phytochemicals and repurposing of FDA approved antiviral drugs unravels lead molecules as potential inhibitors of coronavirus 3C-like protease enzyme

Bahadur Gurung A, Ajmal Ali M, Lee J, Abul Farah M, Mashay Al-Anazi K.

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An integrated national scale SARS-CoV-2 genomic surveillance network

COVID-19 Genomics UK (COG-UK) consortiumcontact@cogconsortium.uk.

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Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection

Sharma A, Garcia G Jr, Wang Y, Plummer JT, Morizono K, Arumugaswami V, Svendsen CN.

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Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients

Suthar MS, Zimmerman MG, Kauffman RC, Mantus G, Linderman SL, Hudson WH, Vanderheiden A, Nyhoff L, Davis CW, Adekunle O, Affer M, Sherman M, Reynolds S, Verkerke HP, Alter DN, Guarner J, Bryksin J, Horwath MC, Arthur CM, Saakadze N, Smith GH, Edupuganti S, Scherer EM, Hellmeister K, Cheng A, Morales JA, Neish AS, Stowell SR, Frank F, Ortlund E, Anderson EJ, Menachery VD, Rouphael N, Mehta AK, Stephens DS, Ahmed R, Roback JD, Wrammert J.

Abstract:

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The immunology of COVID-19: is immune modulation an option for treatment?

Zhong J, Tang J, Ye C, Dong L.

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Time-series analyses of directional sequence changes in SARS-CoV-2 genomes and an efficient search method for candidates for advantageous mutations for growth in human cells

Wada K, Wada Y, Ikemura T.

Abstract:

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Lung microbiome and coronavirus disease 2019 (COVID-19): Possible link and implications

Khatiwada S, Subedi A.

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Phylogenomic proximity and comparative proteomic analysis of SARS-CoV-2

Prathiviraj R, Kiran GS, Selvin J.

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Molecular biology of coronaviruses: current knowledge

Artika IM, Dewantari AK, Wiyatno A.

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In Silico Identification of Potential Inhibitors of ADP-Ribose Phosphatase of SARS-CoV-2 nsP3 by Combining E-Pharmacophore- and Receptor-Based Virtual Screening of Database

Debnath P, Debnath B, Bhaumik S, Debnath S.

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Predicted therapeutic targets for COVID-19 disease by inhibiting SARS-CoV-2 and its related receptors

Balmeh N, Mahmoudi S, Mohammadi N, Karabedianhajiabadi A.

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Structure-based drug designing towards the identification of potential anti-viral for COVID-19 by targeting endoribonuclease NSP15

Krishnan DA, Sangeetha G, Vajravijayan S, Nandhagopal N, Gunasekaran K.

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Identification and classification of differentially expressed genes reveal potential molecular signature associated with SARS-CoV-2 infection in lung adenocarcinomal cells

Soremekun OS, Omolabi KF, Soliman MES.

Abstract:

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Protein based biomarkers for non-invasive Covid-19 detection

Kaur M, Tiwari S, Jain R.

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Resilience to crises of Thai MICE stakeholders: A longitudinal study of the destination image of Thailand as a MICE destination

Rittichainuwat B, Laws E, Maunchontham R, Rattanaphinanchai S, Muttamara S, Mouton K, Lin Y, Suksai C.

Abstract:

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Molecular docking suggests repurposing of brincidofovir as a potential drug targeting SARS-CoV-2 ACE2 receptor and main protease

Hussien MA, Abdelaziz AEM.

Abstract:

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Macrophage activation syndrome and COVID-19

Otsuka R, Seino KI.

Abstract:

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Genome evolution of SARS-CoV-2 and its virological characteristics

Nakagawa S, Miyazawa T.

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Solvability and stability of a fractional dynamical system of the growth of COVID-19 with approximate solution by fractional Chebyshev polynomials

Hadid SB, Ibrahim RW, Altulea D, Momani S.

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Immunoinformatics characterization of SARS-CoV-2 spike glycoprotein for prioritization of epitope based multivalent peptide vaccine

Ismail S, Ahmad S, Azam SS.

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Chemical-informatics approach to COVID-19 drug discovery: Exploration of important fragments and data mining based prediction of some hits from natural origins as main protease (Mpro) inhibitors

Ghosh K, Amin SA, Gayen S, Jha T.

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Crystal structure, chemical reactivity, kinetic and thermodynamic studies of new ligand derived from 4-hydroxycoumarin: Interaction with SARS-CoV-2

Ait-Ramdane-Terbouche C, Abdeldjebar H, Terbouche A, Lakhdari H, Bachari K, Roisnel T, Hauchard D.

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Inhibition of SARS-CoV-2 main protease 3CL(pro) by means of α-ketoamide and pyridone-containing pharmaceuticals using in silico molecular docking

Elzupir AO.

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Computational evaluation of major components from plant essential oils as potent inhibitors of SARS-CoV-2 spike protein

Kulkarni SA, Nagarajan SK, Ramesh V, Palaniyandi V, Selvam SP, Madhavan T.

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Inhibitory activity of hydroxychloroquine on COVID-19 main protease: An insight from MD-simulation studies

Baildya N, Ghosh NN, Chattopadhyay AP.

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Computational Alanine Scanning and Structural Analysis of the SARS-CoV-2 Spike Protein/Angiotensin-Converting Enzyme 2 Complex

Laurini E, Marson D, Aulic S, Fermeglia M, Pricl S.

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Anti-COVID-19 multi-epitope vaccine designs employing global viral genome sequences

Zaheer T, Waseem M, Waqar W, Dar HA, Shehroz M, Naz K, Ishaq Z, Ahmad T, Ullah N, Bakhtiar SM, Muhammad SA, Ali A.

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Molecular docking analysis of N-substituted Oseltamivir derivatives with the SARS-CoV-2 main protease

Belhassan A, Chtita S, Zaki H, Lakhlifi T, Bouachrine M.

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Towards the design of epitope candidates for Coronavirus 2

Odhar HA, Ahjel SW, Humadi SS.

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Lactate dehydrogenase: an old enzyme reborn as a COVID-19 marker (and not only)

Panteghini M.

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Viral, host and environmental factors that favor anthropozoonotic spillover of coronaviruses: An opinionated review, focusing on SARS-CoV, MERS-CoV and SARS-CoV-2

da Silva PG, Mesquita JR, de São José Nascimento M, Ferreira VAM.

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The use of knowledge management tools in viroinformatics. Example study of a highly conserved sequence motif in Nsp3 of SARS-CoV-2 as a therapeutic target

Robson B.

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Host Polymorphisms May Impact SARS-CoV-2 Infectivity

Brest P, Refae S, Mograbi B, Hofman P, Milano G.

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Establishment and validation of a drug-target microarray for SARS-CoV-2

Chen P, Zeng Z, Du H.

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Covid-19: Spiking a focus on men's health

Wittert G, McLachlan R.

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Conformational transition of SARS-CoV-2 spike glycoprotein between its closed and open states

Gur M, Taka E, Yilmaz SZ, Kilinc C, Aktas U, Golcuk M.

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Immunoinformatics-guided design of an epitope-based vaccine against severe acute respiratory syndrome coronavirus 2 spike glycoprotein

Rakib A, Sami SA, Mimi NJ, Chowdhury MM, Eva TA, Nainu F, Paul A, Shahriar A, Tareq AM, Emon NU, Chakraborty S, Shil S, Mily SJ, Ben Hadda T, Almalki FA, Emran TB.

Abstract:

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Emerging strategies on in silico drug development against COVID-19: challenges and opportunities

Yadav M, Dhagat S, Eswari JS.

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HLA alleles frequencies and susceptibility to COVID-19 in a group of 99 Italian patients

Novelli A, Andreani M, Biancolella M, Liberatoscioli L, Passarelli C, Colona VL, Rogliani P, Leonardis F, Campana A, Carsetti R, Andreoni M, Bernardini S, Novelli G, Locatelli F.

Abstract:

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Altered immune cell differentiation in the lungs of patients with critical COVID-19

van Grinsven E, Jansen K.

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A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction

Ejemel M, Li Q, Hou S, Schiller ZA, Tree JA, Wallace A, Amcheslavsky A, Kurt Yilmaz N, Buttigieg KR, Elmore MJ, Godwin K, Coombes N, Toomey JR, Schneider R, Ramchetty AS, Close BJ, Chen DY, Conway HL, Saeed M, Ganesa C, Carroll MW, Cavacini LA, Klempner MS, Schiffer CA, Wang Y.

Abstract:

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Natural killer cell immunotypes related to COVID-19 disease severity

Maucourant C, Filipovic I, Ponzetta A, Aleman S, Cornillet M, Hertwig L, Strunz B, Lentini A, Reinius B, Brownlie D, Gomez AC, Ask EH, Hull RM, Haroun-Izquierdo A, Schaffer M, Klingström J, Folkesson E, Buggert M, Sandberg JK, Eriksson LI, Rooyackers O, Ljunggren HG, Malmberg KJ, Michaëlsson J, Marquardt N, Hammer Q, Strålin K, Björkström NK; Karolinska COVID-19 Study Group.

Abstract:

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Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, Lewin HA.

Abstract:

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Pathologic features of COVID-19: A concise review

Tabary M, Khanmohammadi S, Araghi F, Dadkhahfar S, Tavangar SM.

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Antiviral Potential of Nanoparticles-Can Nanoparticles Fight Against Coronaviruses?

Gurunathan S, Qasim M, Choi Y, Do JT, Park C, Hong K, Kim JH, Song H.

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SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence

Mohammad S, Bouchama A, Mohammad Alharbi B, Rashid M, Saleem Khatlani T, Gaber NS, Malik SS.

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Exhibits High Predicted Binding Affinity to ACE2 from Lagomorphs (Rabbits and Pikas)

Preziuso S.

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The Sialoside-Binding Pocket of SARS-CoV-2 Spike Glycoprotein Structurally Resembles MERS-CoV

Awasthi M, Gulati S, Sarkar DP, Tiwari S, Kateriya S, Ranjan P, Verma SK.

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Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?

Das UN.

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DNA/RNA Electrochemical Biosensing Devices a Future Replacement of PCR Methods for a Fast Epidemic Containment

Santhanam M, Algov I, Alfonta L.

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Deciphering SARS-CoV-2 Virologic and Immunologic Features

Lebeau G, Vagner D, Frumence É, Ah-Pine F, Guillot X, Nobécourt E, Raffray L, Gasque P.

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Progress in Developing Inhibitors of SARS-CoV-2 3C-Like Protease

Li Q, Kang C.

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Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic

Pillay S, Giandhari J, Tegally H, Wilkinson E, Chimukangara B, Lessells R, Moosa Y, Mattison S, Gazy I, Fish M, Singh L, Khanyile KS, San JE, Fonseca V, Giovanetti M, Alcantara LC Jr, de Oliveira T.

Abstract:

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Putative SARS-CoV-2 M(pro) Inhibitors from an In-House Library of Natural and Nature-Inspired Products: A Virtual Screening and Molecular Docking Study

Mazzini S, Musso L, Dallavalle S, Artali R.

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Proposal of De Novo Antigen Test for COVID-19: Ultrasensitive Detection of Spike Proteins of SARS-CoV-2

Kyosei Y, Namba M, Yamura S, Takeuchi R, Aoki N, Nakaishi K, Watabe S, Ito E.

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Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications

Farsalinos K, Eliopoulos E, Leonidas DD, Papadopoulos GE, Tzartos S, Poulas K.

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[Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI-AeDA-GPA-DGAKI Position Paper (Pocket-Guide)]

Pfaar O, Klimek L, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mösges R, Saloga J, Staubach P, Stute P, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mülleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wöhrl S, Niederberger-Leppin V, Pali-Schöll I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R,

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Evaluation on testing of deep throat saliva and lower respiratory tract specimens with Xpert Xpress SARS-CoV-2 assay

Wong RC, Wong AH, Ho YI, Leung EC, Lai RW.

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Missense mutations in SARS-CoV2 genomes from Indian patients

Hassan SS, Choudhury PP, Roy B, Jana SS.

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Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study

Young BE, Fong SW, Chan YH, Mak TM, Ang LW, Anderson DE, Lee CY, Amrun SN, Lee B, Goh YS, Su YCF, Wei WE, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Chen YYC, Barkham T, Lin RTP, Maurer-Stroh S, Leo YS, Wang LF, Renia L, Lee VJ, Smith GJD, Lye DC, Ng LFP.

Abstract:

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COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2

Mittal A, Manjunath K, Ranjan RK, Kaushik S, Kumar S, Verma V.

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Real-time public health communication of local SARS-CoV-2 genomic epidemiology

Kalinich CC, Jensen CG, Neugebauer P, Petrone ME, Peña-Hernández M, Ott IM, Wyllie AL, Alpert T, Vogels CBF, Fauver JR, Grubaugh ND, Brito AF.

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The Spectrum of Histopathologic Findings in Lungs of Patients with Fatal COVID-19 Infection

Roden AC, Bois MC, Johnson TF, Aubry MC, Alexander MP, Hagen CE, Lin PT, Quinton RA, Maleszewski JJ, Boland JM.

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Potential Role of Peptide-Based Antiviral Therapy Against SARS-CoV-2 Infection

Maiti BK.

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The Potential of Antimicrobial Peptides as an Antiviral Therapy against COVID-19

Elnagdy S, AlKhazindar M.

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SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral Epithelium

Wang Z, Zhou J, Marshall B, Rekaya R, Ye K, Liu HX.

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Metabolic Efficacy of Phosphate Prodrugs and the Remdesivir Paradigm

Wiemer AJ.

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Susceptibility to SARS, MERS, and COVID-19 from animal health perspective

Gautam A, Kaphle K, Shrestha B, Phuyal S.

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SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients

Klimstra WB, Tilston-Lunel NL, Nambulli S, Boslett J, McMillen CM, Gilliland T, Dunn MD, Sun C, Wheeler SE, Wells A, Hartman AL, McElroy AK, Reed DS, Rennick LJ, Duprex WP.

Abstract:

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Safety considerations in the bioanalytical laboratories handling specimens from coronavirus disease 2019 patients

Chen Z, Sikorski TW.

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Lipid-based nano delivery of Tat-peptide conjugated drug or vaccine-promising therapeutic strategy for SARS-CoV-2 treatment

Ansari MA, Almatroudi A, Alzohairy MA, AlYahya S, Alomary MN, Al-Dossary HA, Alghamdi S.

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Agent-based modelling for SARS-CoV-2 epidemic prediction and intervention assessment: A methodological appraisal

Maziarz M, Zach M.

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Animal and translational models of SARS-CoV-2 infection and COVID-19

Johansen MD, Irving A, Montagutelli X, Tate MD, Rudloff I, Nold MF, Hansbro NG, Kim RY, Donovan C, Liu G, Faiz A, Short KR, Lyons JG, McCaughan GW, Gorrell MD, Cole A, Moreno C, Couteur D, Hesselson D, Triccas J, Neely GG, Gamble JR, Simpson SJ, Saunders BM, Oliver BG, Britton WJ, Wark PA, Nold-Petry CA, Hansbro PM.

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Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide

Isabel S, Graña-Miraglia L, Gutierrez JM, Bundalovic-Torma C, Groves HE, Isabel MR, Eshaghi A, Patel SN, Gubbay JB, Poutanen T, Guttman DS, Poutanen SM.

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GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

Hattori SI, Higshi-Kuwata N, Raghavaiah J, Das D, Bulut H, Davis DA, Takamatsu Y, Matsuda K, Takamune N, Kishimoto N, Okamura T, Misumi S, Yarchoan R, Maeda K, Ghosh AK, Mitsuya H.

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Angiotensin Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use Among Outpatients Diagnosed With COVID-19

Bae DJ, Tehrani DM, Rabadia SV, Frost M, Parikh RV, Calfon-Press M, Aksoy O, Umar S, Ardehali R, Rabbani A, Bokhoor P, Nsair A, Currier J, Tobis J, Fonarow GC, Dave R, Rafique AM.

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Lead Finding from Selected Flavonoids with Antiviral (SARS-CoV-2) Potentials against COVID-19: An in-silico Evaluation

Gorla US, Rao GK, Kulandaivelu US, Alavala RR, Panda SP.

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SARS-CoV-2 exhibits intra-host genomic plasticity and low-frequency polymorphic quasispecies

Karamitros T, Papadopoulou G, Bousali M, Mexias A, Tsiodras S, Mentis A.

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Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain

Mukherjee S, Bhattacharyya D, Bhunia A.

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A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry

Chen Y, Lear T, Evankovich J, Larsen M, Lin B, Alfaras I, Kennerdell J, Salminen L, Camarco D, Lockwood K, Liu J, Myerburg M, McDyer J, Liu Y, Finkel T, Chen B.

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Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase

Cross RW, Agans KN, Prasad AN, Borisevich V, Woolsey C, Deer DJ, Dobias NS, Geisbert JB, Fenton KA, Geisbert TW.

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Elovanoid-N32 or RvD6-isomer decrease ACE2 and binding of S protein RBD after injury or INFγ in the eye

Pham TL, He J, Kakazu AH, Calandria J, Do KV, Nshimiyimana R, Petasis NA, Bazan HEP, Bazan NG.

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Salivary anti-SARS-CoV-2 IgA as an accessible biomarker of mucosal immunity against COVID-19

Varadhachary A, Chatterjee D, Garza J, Garr RP, Foley C, Letkeman AF, Dean J, Haug D, Breeze J, Traylor R, Malek A, Nath R, Linbeck L.

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Detection, prevalence, and duration of humoral responses to SARS-CoV-2 under conditions of limited population exposure

Ripperger TJ, Uhrlaub JL, Watanabe M, Wong R, Castaneda Y, Pizzato HA, Thompson MR, Bradshaw C, Weinkauf CC, Bime C, Erickson HL, Knox K, Bixby B, Parthasarathy S, Chaudhary S, Natt B, Cristan E, El Aini T, Rischard F, Campion J, Chopra M, Insel M, Sam A, Knepler JL, Capaldi AP, Spier CM, Dake MD, Edwards T, Kaplan ME, Scott SJ, Hypes C, Mosier J, Harris DT, Lafleur BJ, Sprissler R, Nikolich-Zugich J, Bhattacharya D.

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Genomic Diversity of SARS-CoV-2 During Early Introduction into the United States National Capital Region

Thielen PM, Wohl S, Mehoke T, Ramakrishnan S, Kirsche M, Falade-Nwulia O, Trovao NS, Erlund A, Howser C, Sadowski N, Morris P, Hopkins M, Schwartz M, Fan Y, Gniazdowski V, Lessler J, Sauer L, Schatz MC, Evans JD, Ray SC, Timp W, Mostafa HH.

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Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera

Oguntuyo KY, Stevens CS, Hung CT, Ikegame S, Acklin JA, Kowdle SS, Carmichael JC, Chiu HP, Azarm KD, Haas GD, Amanat F, Klingler J, Baine I, Arinsburg S, Bandres JC, Siddiquey MN, Schilke RM, Woolard MD, Zhang H, Duty AJ, Kraus TA, Moran TM, Tortorella D, Lim JK, Gamarnik AV, Hioe CE, Zolla-Pazner S, Ivanov SS, Kamil JP, Krammer F, Lee B.

Abstract:

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Functional SARS-CoV-2-specific immune memory persists after mild COVID-19

Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PM, Thouvenel C, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Rathe J, Stokes C, Wrenn S, Fiala B, Carter LP, Hamerman JA, King NP, Gale M, Campbell DJ, Rawlings D, Pepper M.

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A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

Kreye J, Reincke SM, Kornau HC, Sanchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Hoeltje M, Dietert K, Stoeffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Mueller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Pruess

Abstract:

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Discovery of Clioquinol and Analogues as Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus 2 Infection, ACE2 and ACE2 - Spike Protein Interaction In Vitro

Olaleye OA, Kaur M, Onyenaka C, Adebusuyi T.

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Discovery of COVID-19 Inhibitors Targeting the SARS-CoV2 Nsp13 Helicase

White MA, Lin W, Cheng X.

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Rational Design of SARS-CoV-2 Spike Glycoproteins To Increase Immunogenicity By T Cell Epitope Engineering

Ong E, Huang X, Pearce R, Zhang Y, He Y.

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The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins

Jaroszewski L, Iyer M, Alisoltani A, Sedova M, Godzik A.

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In Silico Design of siRNAs Targeting Existing and Future Respiratory Viruses with VirusSi

Zhang D, Lu J.

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Efficacy of Targeting SARS-CoV-2 by CAR-NK Cells

Ma M, Badeti S, Geng K, Liu D.

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K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia

Zheng J, Roy Wong LY, Li K, Verma AK, Ortiz M, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S.

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SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2

Heaton BE, Trimarco JD, Hamele CE, Harding AT, Tata A, Zhu X, Tata PR, Smith CM, Heaton NS.

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Structure-Based Drug Design of an Inhibitor of the SARS-CoV-2 (COVID-19) Main Protease Using Free Software: A Tutorial for Students and Scientists

Zhang S, Krumberger M, Morris MA, Parrocha CMT, Griffin JH, Kreutzer A, Nowick JS.

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Self-Collected Anterior Nasal and Saliva Specimens versus Healthcare Worker-Collected Nasopharyngeal Swabs for the Molecular Detection of SARS-CoV-2

Hanson KE, Barker AP, Hillyard DR, Gilmore N, Barrett JW, Orlandi RR, Shakir SM.

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Cryo-electron microscopy structure of the SADS-CoV spike glycoprotein provides insights into an evolution of unique coronavirus spike proteins

Guan H, Wang Y, Perčulija V, Saeed AFUH, Liu Y, Li J, Jan SS, Li Y, Zhu P, Ouyang S.

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ACE2 & TMPRSS2 Expressions in Head & Neck Tissues: A Systematic Review

Lechien JR, Radulesco T, Calvo-Henriquez C, Chiesa-Estomba CM, Hans S, Barillari MR, Cammaroto G, Descamps G, Hsieh J, Vaira L, De Riu G, Sowerby L, Gengler I, Michel J, Saussez S.

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3d virtual pathohistology of lung tissue from COVID-19 patients based on phase contrast x-ray tomography

Eckermann M, Frohn J, Reichardt M, Osterhoff M, Sprung M, Westermeier F, Tzankov A, Kühnel M, Jonigk D, Salditt T.

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Molecular docking and simulation studies on SARS-CoV-2 M(pro) reveals Mitoxantrone, Leucovorin, Birinapant, and Dynasore as potent drugs against COVID-19

Lokhande KB, Doiphode S, Vyas R, Swamy KV.

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Antibody response in a family with COVID-19

Henriksen S, Trydal √ò, Sigurdsen SE, Tylden GD, Rinaldo CH.

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ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteogenic Differentiation

Xia Y, Fan X, Yang H, Li L, He C, Cheng C, Haag R.

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Epidermal Neural Crest Stem Cells as a Perspective for COVID-19 Treatment

Salehi MS, Pandamooz S, Jurek B.

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Post-mortem viral dynamics and tropism in COVID-19 patients in correlation with organ damage

Skok K, Stelzl E, Trauner M, Kessler HH, Lax SF.

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Swabbing Thoroughly People for COVID-19 Positivity. Insights on the Main Bio-analytical and Microbiology Bias and Concerns

Chirumbolo S.

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COVID-19 immunity, scorching temperatures and telescope accident

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Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity

Islam MR, Hoque MN, Rahman MS, Alam ASMRU, Akther M, Puspo JA, Akter S, Sultana M, Crandall KA, Hossain MA.

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Comparison of nonhuman primates identified the suitable model for COVID-19

Lu S, Zhao Y, Yu W, Yang Y, Gao J, Wang J, Kuang D, Yang M, Yang J, Ma C, Xu J, Qian X, Li H, Zhao S, Li J, Wang H, Long H, Zhou J, Luo F, Ding K, Wu D, Zhang Y, Dong Y, Liu Y, Zheng Y, Lin X, Jiao L, Zheng H, Dai Q, Sun Q, Hu Y, Ke C, Liu H, Peng X.

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On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2

Sauvat A, Ciccosanti F, Colavita F, Di Rienzo M, Castilletti C, Capobianchi MR, Kepp O, Zitvogel L, Fimia GM, Piacentini M, Kroemer G.

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COVID-19: fighting the invisible enemy with microRNA

Chauhan N, Jaggi M, Chauhan SC, Yallapu MM.

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The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature

LoPresti M, Beck DB, Duggal P, Cummings DAT, Solomon BD.

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Spectrum of virucidal activity from ultraviolet to infrared radiation

Horton L, Torres AE, Narla S, Lyons AB, Kohli I, Gelfand JM, Ozog DM, Hamzavi IH, Lim HW.

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How a small virus changed our world and the special role of anosmia

Fokkens WJ.

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Network pharmacology suggests biochemical rationale for treating COVID-19 symptoms with a Traditional Chinese Medicine

Zhang DH, Zhang X, Peng B, Deng SQ, Wang YF, Yang L, Zhang KZ, Ling CQ, Wu KL.

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Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase

Cross RW, Agans KN, Prasad AN, Borisevich V, Woolsey C, Deer DJ, Dobias NS, Geisbert JB, Fenton KA, Geisbert TW.

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An in-silico evaluation of dietary components for structural inhibition of SARS-Cov-2 main protease

Pandey AK, Verma S.

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The development of Coronavirus 3C-Like protease (3CL(pro)) inhibitors from 2010 to 2020

Liu Y, Liang C, Xin L, Ren X, Tian L, Ju X, Li H, Wang Y, Zhao Q, Liu H, Cao W, Xie X, Zhang D, Wang Y, Jian Y.

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Propolis and coronavirus disease 2019 (COVID-19): Lessons from nature

Scorza CA, Gonçalves VC, Scorza FA, Fiorini AC, de Almeida AG, Fonseca MCM, Finsterer J.

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Possible role of HLA class-I genotype in SARS-CoV-2 infection and progression: A pilot study in a cohort of Covid-19 Spanish patients

Iturrieta-Zuazo I, Rita CG, García-Soidán A, de Malet Pintos-Fonseca A, Alarcón NA, Rodríguez RP, Velarde AT, Villar SS, Alabau JLC, Gañán IN.

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Multiplexed Nanomaterial-Based Sensor Array for Detection of COVID-19 in Exhaled Breath

Shan B, Broza YY, Li W, Wang Y, Wu S, Liu Z, Wang J, Gui S, Wang L, Zhang Z, Liu W, Zhou S, Jin W, Zhang Q, Hu D, Lin L, Zhang Q, Li W, Wang J, Liu H, Pan Y, Haick H.

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Genetic tracing of HCoV-19 for the re-emerging outbreak of COVID-19 in Beijing, China

Yang J, Niu P, Chen L, Wang L, Zhao L, Huang B, Ma J, Hu S, Wu L, Wu G, Huang C, Bi Y, Tan W.

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An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors

Trezza A, Iovinelli D, Santucci A, Prischi F, Spiga O.

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Potential Leads from Liquorice against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies

Sinha SK, Prasad SK, Islam MA, Chaudhary SK, Singh S, Shakya A.

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Of Mice and Men: The Coronavirus MHV and Mouse Models as a Translational Approach to Understand SARS-CoV-2

Körner RW, Majjouti M, Alcazar MAA, Mahabir E.

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Enhanced Binding of SARS-CoV-2 Spike Protein to Receptor by Distal Polybasic Cleavage Sites

Qiao B, Olvera de la Cruz M.

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Unravelling host-pathogen interactions: ceRNA network in SARS-CoV-2 infection (COVID-19)

Arora S, Singh P, Dohare R, Jha R, Ali Syed M.

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Various interferon (IFN)-inducible transmembrane (IFITM) proteins for COVID-19, is there a role for the combination of mycophenolic acid and interferon?

Dowran R, Nabavi SF, Habtemariam S, Banach M, Shahmohamadnejad S, Cismaru CA, Berindan-Neagoe I, Sahebnasagh A, Nabavi SM.

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Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19

Narasaraju T.

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Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19

Zhang H, Wang CY, Zhou P, Yue H, Du R.

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Mechanistic insights into SARS-CoV-2 epidemic via revealing the features of SARS-CoV-2 coding proteins and host responses upon its infection

Qin S, Xia X, Shi X, Ji X, Ma F, Chen L.

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Based on Principles and Insights of COVID-19 Epidemiology, Genome Sequencing, and Pathogenesis: Retrospective Analysis of Sinigrin and Prolixin(RX) (Fluphenazine) Provides Off-Label Drug Candidates

Nazeam J, Mohammed EZ, Raafat M, Houssein M, Elkafoury A, Hamdy D, Jamil L.

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A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy

Miao X, Luo Y, Huang X, Lee SMY, Yuan Z, Tang Y, Chen L, Wang C, Wu F, Xu Y, Jiang W, Gao W, Song X, Yan Y, Pang T, Chen C, Zou Y, Fu W, Wan L, Gilbert-Jaramillo J, Knight M, Tan TK, Rijal P, Townsend A, Sun J, Liu X, James W, Tsun A, Xu Y.

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K18-hACE2 mice develop respiratory disease resembling severe COVID-19

Yinda CK, Port JR, Bushmaker T, Owusu IO, Avanzato VA, Fischer RJ, Schulz JE, Holbrook MG, Hebner MJ, Rosenke R, Thomas T, Marzi A, Best SM, de Wit E, Shaia C, van Doremalen N, Munster VJ.

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Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15

Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE.

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Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening

Zhu W, Xu M, Chen CZ, Guo H, Shen M, Hu X, Shinn P, Klumpp-Thomas C, Michael SG, Zheng W.

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Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity

Saini S, Saini A, Thakur CJ, Kumar V, Gupta RD, Sharma JK.

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The Application of Single-Cell RNA Sequencing in Vaccinology

Noé A, Cargill TN, Nielsen CM, Russell AJC, Barnes E.

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Potential chimeric peptides to block the SARS-CoV-2 spike receptor-binding domain

Barh D, Tiwari S, Silva Andrade B, Giovanetti M, Almeida Costa E, Kumavath R, Ghosh P, Góes-Neto A, Carlos Junior Alcantara L, Azevedo V.

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Network Pharmacology Integrated Molecular Docking Reveals the Mechanism of Anisodamine Hydrobromide Injection against Novel Coronavirus Pneumonia

Su J, Liu Z, Liu C, Li X, Wang Y, Zhao J, Wu Q, Zheng S, Zhang Y.

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Translation of genomic epidemiology of infectious pathogens: Enhancing African genomics hubs for outbreaks

Oboh MA, Omoleke SA, Ajibola O, Manneh J, Kanteh A, Sesay AK, Amambua-Ngwa A.

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In silico molecular investigations of pyridine N-Oxide compounds as potential inhibitors of SARS-CoV-2: 3D QSAR, molecular docking modeling, and ADMET screening

Ghaleb A, Aouidate A, Ayouchia HBE, Aarjane M, Anane H, Stiriba SE.

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Animal coronaviruses and SARS-CoV-2

Zhang G, Li B, Yoo D, Qin T, Zhang X, Jia Y, Cui S.

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Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

Liu P, Liu H, Sun Q, Liang H, Li C, Deng X, Liu Y, Lai L.

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From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses

Kirtipal N, Bharadwaj S, Kang SG.

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Molecular Docking and Virtual Screening based prediction of drugs for COVID-19

Talluri S.

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Plasma from recovered COVID-19 subjects inhibits spike protein binding to ACE2 in a microsphere-based inhibition assay

Gniffke EP, Harrington WE, Dambrauskas N, Jiang Y, Trakhimets O, Vigdorovich V, Frenkel L, Sather DN, Smith SEP.

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The potential involvement of P2X7 receptor in COVID-19 pathogenesis: a new therapeutic target?

Pacheco PAF, Faria RX.

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Serum concentrations of Krebs von den Lungen-6 in different COVID-19 phenotypes

d'Alessandro M, Cameli P, Bergantini L, Franchi F, Scolletta S, Bargagli E.

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Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals

Zhang F, Gan R, Zhen Z, Hu X, Li X, Zhou F, Liu Y, Chen C, Xie S, Zhang B, Wu X, Huang Z.

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Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications on COVID-19 immunity

McAndrews KM, Dowlatshahi DP, Dai J, Becker LM, Hensel J, Snowden LM, Leveille JM, Brunner MR, Holden K, Hopkins NS, Harris A, Kumpati JJ, Whitt MA, Lee JJ, Ostrosky-Zeichner L, Papanna R, LeBleu V, Allison J, Kalluri R.

Abstract:

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Protein reliability analysis and virtual screening of natural inhibitors for SARS-CoV-2 main protease (M(pro)) through docking, molecular mechanic & dynamic, and ADMET profiling

Kapusta K, Kar S, Collins JT, Franklin LM, Kolodziejczyk W, Leszczynski J, Hill GA.

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IL-18 and infections: Is there a role for targeted therapies?

Vecchié A, Bonaventura A, Toldo S, Dagna L, Dinarello CA, Abbate A.

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A diagnostic genomic signal processing (GSP)-based system for automatic feature analysis and detection of COVID-19

Naeem SM, Mabrouk MS, Marzouk SY, Eldosoky MA.

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Specificity and Performance of Nucleocapsid and Spike-based SARS-CoV-2 Serologic Assays

Rikhtegaran Tehrani Z, Saadat S, Saleh E, Ouyang X, Constantine N, DeVico AL, Harris AD, Lewis GK, Kottilil S, Sajadi MM.

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Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers and convalescent plasma donors: a cohort study using a rapid and sensitive high-throughput neutralization assay

Zeng C, Evans JP, Pearson R, Qu P, Zheng YM, Robinson RT, Hall-Stoodley L, Yount J, Pannu S, Mallampalli RK, Saif L, Oltz E, Lozanski G, Liu SL.

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Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

Snyder TM, Gittelman RM, Klinger M, May DH, Osborne EJ, Taniguchi R, Zahid HJ, Kaplan IM, Dines JN, Noakes MN, Pandya R, Chen X, Elasady S, Svejnoha E, Ebert P, Pesesky MW, De Almeida P, O'Donnell H, DeGottardi Q, Keitany G, Lu J, Vong A, Elyanow R, Fields P, Greissl J, Baldo L, Semprini S, Cerchione C, Mazza M, Delmonte OM, Dobbs K, Carreño-Tarragona G, Barrio S, Imberti L, Sottini A, Quiros-Roldan E, Rossi C, Biondi A, Bettini LR, D'Angio M, Bonfanti P, Tompkins MF, Alba C, Dalgard C, Samb

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SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

Fagre A, Lewis J, Eckley M, Zhan S, Rocha SM, Sexton NR, Burke B, Geiss BJ, Peersen O, Kading R, Rovnak J, Ebel GD, Tjalkens RB, Aboellail T, Schountz T.

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Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Sheltzer JM, Kjolby M, Pöhlmann S.

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De novo design of ACE2 protein decoys to neutralize SARS-CoV-2

Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Hsiang TY, Esser-Nobis K, Yu K, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric R, Walkey CD, Swanson R, Gale M, Blancas-Mejia LM, Yen HL, Silva DA.

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Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

Klimczak LJ, Randall TA, Saini N, Li JL, Gordenin DA.

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Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA.

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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

Rosa BA, Ahmed M, Singh DK, Choreno-Parra JA, Cole J, Jimenez-Alvarez LA, Rodriguez-Reyna TS, Singh B, Golzalez O, Carrion R, Schlesinger LS, Martin J, Zuniga J, Mitreva M, Khader SA, Kaushal D.

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IFN- γ and TNF- α drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation

Zhang F, Mears JR, Shakib L, Beynor JI, Shanaj S, Korsunsky I, Nathan A, Donlin LT, Raychaudhuri S.

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Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB.

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Computational Hot-Spot Analysis of the SARS-CoV-2 Receptor Binding Domain / ACE2 Complex

Rosario PA, McNaughton BR.

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Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells

Tristan CA, Ormanoglu P, Slamecka J, Malley C, Chu PH, Jovanovic VM, Gedik Y, Bonney C, Barnaeva E, Braisted J, Mallanna SK, Dorjsuren D, Iannotti MJ, Voss TC, Michael S, Simeonov A, Singeç I.

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A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Nolan S, Vignali M, Klinger M, Dines JN, Kaplan IM, Svejnoha E, Craft T, Boland K, Pesesky M, Gittelman RM, Snyder TM, Gooley CJ, Semprini S, Cerchione C, Mazza M, Delmonte OM, Dobbs K, Carreño-Tarragona G, Barrio S, Sambri V, Martinelli G, Goldman JD, Heath JR, Notarangelo LD, Carlson JM, Martinez-Lopez J, Robins HS.

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A Rational Design of a Multi-Epitope Vaccine Against SARS-CoV-2 Which Accounts for the Glycan Shield of the Spike Glycoprotein

Martin WR, Cheng F.

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Geographic and Genomic Distribution of SARS-CoV-2 Mutations

Mercatelli D, Giorgi FM.

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Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis

Alexpandi R, De Mesquita JF, Pandian SK, Ravi AV.

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Immune Response and COVID-19: A mirror image of Sepsis

López-Collazo E, Avendaño-Ortiz J, Martín-Quirós A, Aguirre LA.

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Comparison of Growth Patterns of COVID-19 Cases through the ARIMA and Gompertz Models. Case Studies: Austria, Switzerland, and Israel

Diaz Perez FJ, Chinarro D, Otin RP, Martín RD, Diaz M, Mouhaffel AG.

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Repurposing of SARS-CoV nucleocapsid protein specific nuclease resistant RNA aptamer for therapeutics against SARS-CoV-2

Parashar NC, Poddar J, Chakrabarti S, Parashar G.

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Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses

Zhou R, To KK, Wong YC, Liu L, Zhou B, Li X, Huang H, Mo Y, Luk TY, Lau TT, Yeung P, Chan WM, Wu AK, Lung KC, Tsang OT, Leung WS, Hung IF, Yuen KY, Chen Z.

Abstract:

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COVID-19: Nanomedicine Uncovers Blood-Clot Mystery

Saei AA, Sharifi S, Mahmoudi M.

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Interleukin-6 Blocking vs. JAK-STAT Inhibition for Prevention of Lung Injury in Patients with COVID-19

Meletiadis J, Tsiodras S, Tsirigotis P.

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Computational analysis of complement inhibitor compstatin using molecular dynamics

Devaurs D, Antunes DA, Kavraki LE.

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Optimized pseudotyping conditions for the SARS COV-2 Spike glycoprotein

Johnson MC, Lyddon TD, Suarez R, Salcedo B, LePique M, Graham M, Ricana C, Robinson C, Ritter DG.

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Rapid determination and optimisation of berberine from Himalayan Berberis lycium by soxhlet apparatus using CCD-RSM and its quality control as a potential candidate for COVID-19

Katare AK, Singh B, Shukla P, Gupta S, Singh B, Yalamanchili K, Kulshrestha N, Bhanwaria R, Sharma AK, Sharma S, Sneha, Mindala DP, Roy S, Kalgotra R.

Abstract:

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Dynamic Asymmetry Exposes 2019-nCoV Prefusion Spike

Roy S, Jaiswar A, Sarkar R.

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Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence

Vankadari N.

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Interaction of Drug Candidates with Various SARS-CoV-2 Receptors: An in Silico Study to Combat COVID-19

Barros RO, Junior FLCC, Pereira WS, Oliveira NMN, Ramos RM.

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Systemic in Silico Screening in Drug Discovery for Coronavirus Disease (COVID-19) with an Online Interactive Web Server

Xu C, Ke Z, Liu C, Wang Z, Liu D, Zhang L, Wang J, He W, Xu Z, Li Y, Yang Y, Huang Z, Lv P, Wang X, Han D, Li Y, Qiao N, Liu B.

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Molecular binding mechanism and pharmacology comparative analysis of noscapine for repurposing against SARS-CoV-2 protease

Kumar N, Sood D, van der Spek PJ, Sharma HS, Chandra R.

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Mass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein

Nikolaev EN, Indeykina MI, Brzhozovskiy AG, Bugrova AE, Kononikhin AS, Starodubtseva NL, Petrotchenko EV, Kovalev GI, Borchers CH, Sukhikh GT.

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Fast Rescoring Protocols to Improve the Performance of Structure-Based Virtual Screening Performed on Protein-Protein Interfaces

Singh N, Chaput L, Villoutreix BO.

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A Chemoenzymatic Synthesis of the (R(P))-Isomer of the Antiviral Prodrug Remdesivir

Bigley AN, Narindoshvili T, Raushel FM.

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Anti-SARS-CoV-2 Potential of Artemisinins In Vitro

Cao R, Hu H, Li Y, Wang X, Xu M, Liu J, Zhang H, Yan Y, Zhao L, Li W, Zhang T, Xiao D, Guo X, Li Y, Yang J, Hu Z, Wang M, Zhong W.

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Might SARS-CoV-2 Have Arisen via Serial Passage through an Animal Host or Cell Culture?: A potential explanation for much of the novel coronavirus' distinctive genome

Sirotkin K, Sirotkin D.

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How close is SARS-CoV-2 to canine and feline coronaviruses?

Sharun K, Sircar S, Malik YS, Singh RK, Dhama K.

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Molecular epidemiology of SARS CoV-2: a review of current data on genetic variability of the virus

Parczewski M, Ciechanowicz A.

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SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells

Cannalire R, Stefanelli I, Cerchia C, Beccari AR, Pelliccia S, Summa V.

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Are the Clinical Presentations (Phenotypes) of Gitelman's and Bartter's Syndromes Gene Mutations Driven by Their Effects on Intracellular pH, Their "pH" Enotype?

Calò LA, Davis PA.

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Natural killer cell responses to emerging viruses of zoonotic origin

Diaz-Salazar C, Sun JC.

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Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex

Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng ET, Vatandaslar H, Chait BT, Kapoor TM, Darst SA, Campbell EA.

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Pathophysiology of COVID-19: Mechanisms Underlying Disease Severity and Progression

Bohn MK, Hall A, Sepiashvili L, Jung B, Steele S, Adeli K.

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Tannins inhibit SARS-CoV-2 through binding with catalytic dyad residues of 3CL(pro) : An in silico approach with 19 structural different hydrolysable tannins

Khalifa I, Zhu W, Mohammed HHH, Dutta K, Li C.

Abstract:

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Cholesteryl Ester Transfer Protein Impairs Triglyceride Clearance via Androgen Receptor in Male Mice

Palmisano BT, Anozie U, Yu S, Neuman JC, Zhu L, Edington EM, Luu T, Stafford JM.

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Global cataloguing of variations in untranslated regions of viral genome and prediction of key host RNA binding protein-microRNA interactions modulating genome stability in SARS-CoV-2

Mukherjee M, Goswami S.

Abstract:

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Mesenchymal stem cells and exosome therapy for COVID-19: current status and future perspective

Gupta A, Kashte S, Gupta M, Rodriguez HC, Gautam SS, Kadam S.

Abstract:

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A human circulating immune cell landscape in aging and COVID-19

Zheng Y, Liu X, Le W, Xie L, Li H, Wen W, Wang S, Ma S, Huang Z, Ye J, Shi W, Ye Y, Liu Z, Song M, Zhang W, Han JJ, Belmonte JCI, Xiao C, Qu J, Wang H, Liu GH, Su W.

Abstract:

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Regulatory T Cells Tested in Patients With COVID-19 ARDS

Abbasi J.

Abstract:

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Mutational spectra of SARS-CoV-2 orf1ab polyprotein and signature mutations in the United States of America

Banerjee S, Seal S, Dey R, Mondal KK, Bhattacharjee P.

Abstract:

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Atomistic simulation reveals structural mechanisms underlying D614G spike glycoprotein-enhanced fitness in SARS-COV-2

Omotuyi IO, Nash O, Ajiboye OB, Iwegbulam CG, Oyinloye EB, Oyedeji OA, Kashim ZA, Okaiyeto K.

Abstract:

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Profiling of Initial Available SARS-CoV-2 Sequences from Iranian Related COVID-19 Patients

Salehi N, Amiri-Yekta A, Totonchi M.

Abstract:

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High affinity interaction of Solanum tuberosum and Brassica juncea residue smoke water compounds with proteins involved in coronavirus infection

Dave GS, Rakholiya KD, Kaneria MJ, Galvadiya BP, Vyas SR, Kanbi VH, Patel MP.

Abstract:

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Immunomodulatory Therapeutic Proteins in COVID-19: Current Clinical Development and Clinical Pharmacology Considerations

Ji P, Chen J, Golding A, Nikolov NP, Saluja B, Ren YR, Sahajwalla C.

Abstract:

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Comparative study on virus shedding patterns in nasopharyngeal and fecal specimens of COVID-19 patients

Zhang N, Gong Y, Meng F, Shi Y, Wang J, Mao P, Chuai X, Bi Y, Yang P, Wang F.

Abstract:

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Pathogenetic profiling of COVID-19 and SARS-like viruses

Nain Z, Rana HK, Liò P, Islam SMS, Summers MA, Moni MA.

Abstract:

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Angiotensin-converting Enzyme 2 roles in the Pathogenesis of COVID-19

Kenarkoohi A, Maleki M, Safari T, Kafashian M, Saljoughi F, Sohrabipour S.

Abstract:

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Graphene biosensors for bacterial and viral pathogens

Jiang Z, Feng B, Xu J, Qing T, Zhang P, Qing Z.

Abstract:

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Viral Load Kinetics of SARS-CoV-2 Infection in Saliva in Korean Patients: a Prospective Multi-center Comparative Study

Kim SE, Lee JY, Lee A, Kim S, Park KH, Jung SI, Kang SJ, Oh TH, Kim UJ, Lee SY, Kee SJ, Jang HC.

Abstract:

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Structural Basis for Designing Multiepitope Vaccines Against COVID-19 Infection: In Silico Vaccine Design and Validation

Srivastava S, Verma S, Kamthania M, Kaur R, Badyal RK, Saxena AK, Shin HJ, Kolbe M, Pandey KC.

Abstract:

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Dataset for homologous proteins in Drosophila melanogaster for SARS-CoV-2/human interactome

Hussain M, Jabeen N, Shabbir S, Udin N, Aziz B, Amanullah A, Raza F, Baig AA.

Abstract:

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Genome sequencing and the diagnosis of novel coronavirus (SARS-COV-2) in Africa: how far are we?

Shey M, Okeibunor JC, Yahaya AA, Herring BL, Tomori O, Coulibaly SO, Gumede-Moeletsi HN, Mwenda JM, Yoti Z, Wiysonge CS, Talisuna AO.

Abstract:

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Repurposing of known anti-virals as potential inhibitors for SARS-CoV-2 main protease using molecular docking analysis

Hakmi M, Bouricha EM, Kandoussi I, Harti JE, Ibrahimi A.

Abstract:

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Giovanni Di Guardo: Animal Models and Pathogenetic Insights to Covid-19

Di Guardo G.

Abstract:

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[Tracing the origins of SARS-COV-2 in coronavirus phylogenies]

Sallard E, Halloy J, Casane D, van Helden J, Decroly É.

Abstract:

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Low temperature bacterial expression of the neutral amino acid transporters SLC1A5 (ASCT2), and SLC6A19 (B0AT1)

Galluccio M, Pantanella M, Giudice D, Brescia S, Indiveri C.

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Anthraquinone Derivatives as an Immune Booster and their Therapeutic Option Against COVID-19

Khanal P, Patil BM, Chand J, Naaz Y.

Abstract:

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Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection

Klaassen K, Stankovic B, Zukic B, Kotur N, Gasic V, Pavlovic S, Stojiljkovic M.

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SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy

Chung MK, Karnik S, Saef J, Bergmann C, Barnard J, Lederman MM, Tilton J, Cheng F, Harding CV, Young JB, Mehta N, Cameron SJ, McCrae KR, Schmaier AH, Smith JD, Kalra A, Gebreselassie SK, Thomas G, Hawkins ES, Svensson LG.

Abstract:

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Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms

Gupta R, Gant VA, Williams B, Enver T.

Abstract:

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Global multi-omics and systems pharmacological strategy unravel the multi-targeted therapeutic potential of natural bioactive molecules against COVID-19: An in silico approach

Muthuramalingam P, Jeyasri R, Valliammai A, Selvaraj A, Karthika C, Gowrishankar S, Pandian SK, Ramesh M, Chen JT.

Abstract:

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Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection

McCullough PA, Kelly RJ, Ruocco G, Lerma E, Tumlin J, Wheelan K, Katz N, Lepor NE, Vijay K, Carter H, Singh B, McCullough SP, Bhambi BK, Palazzuoli A, De Ferrari GM, Milligan G, Safder T, Tecson KM, Wang DD, McKinnon, O'Neill WW, Zervos M, Risch HA.

Abstract:

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The role of DBP gene polymorphisms in the prevalence of new coronavirus disease 2019 infection and mortality rate

Batur LK, Hekim N.

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(1)H, (13)C, and (15)N backbone chemical shift assignments of the nucleic acid-binding domain of SARS-CoV-2 non-structural protein 3e

Korn SM, Dhamotharan K, Fürtig B, Hengesbach M, Löhr F, Qureshi NS, Richter C, Saxena K, Schwalbe H, Tants JN, Weigand JE, Wöhnert J, Schlundt A.

Abstract:

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COVID-19: An up-to-date review - from morphology to pathogenesis

Bal A, Agrawal R, Vaideeswar P, Arava S, Jain A.

Abstract:

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Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design

Meyer-Almes FJ.

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First proof of the capability of wastewater surveillance for COVID-19 in India through detection of genetic material of SARS-CoV-2

Kumar M, Patel AK, Shah AV, Raval J, Rajpara N, Joshi M, Joshi CG.

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In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2

Vijayakumar BG, Ramesh D, Joji A, Jayachandra Prakasan J, Kannan T.

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Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit?

Stout AE, André NM, Jaimes JA, Millet JK, Whittaker GR.

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Description of a new biosafe procedure for cytological specimens from patients with COVID-19 processed by liquid-based preparations

Straccia P, Rossi ED, Martini M, Mulè A, Cianfrini F, Curatolo M, Cancellieri A, Brunelli C, Zannoni GF, Fadda G.

Abstract:

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ACE polymorphism and COVID-19 outcome

Delanghe JR, Speeckaert MM, De Buyzere ML.

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Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M(pro) and cathepsin L

Sacco MD, Ma C, Lagarias P, Gao A, Townsend JA, Meng X, Dube P, Zhang X, Hu Y, Kitamura N, Hurst B, Tarbet B, Marty MT, Kolocouris A, Xiang Y, Chen Y, Wang J.

Abstract:

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Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories

Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, Xu A, Li J, Dong S, Rothchild A, Zhou J, Murray K, Edmark R, Hong S, Jones L, Zhou Y, Roper R, Mackay S, O'Mahony DS, Dale CR, Wallick JA, Algren HA, Michael ZA, Magis A, Wei W, Price ND, Huang S, Subramanian N, Wang K, Hadlock J, Hood L, Aderem A, Bluestone JA, Lanier LL, Greenberg P, Gottardo R, Davis MM, Goldman JD, Heath JR.

Abstract:

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A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors

Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR.

Abstract:

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Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals

Doddapaneni H, Cregeen SJ, Sucgang R, Meng Q, Qin X, Avadhanula V, Chao H, Menon V, Nicholson E, Henke D, Piedra FA, Rajan A, Momin Z, Kottapalli K, Hoffman KL, Sedlazeck FJ, Metcalf G, Piedra PA, Muzny DM, Petrosino JF, Gibbs RA.

Abstract:

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Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction

Cao W, Dong C, Kim S, Hou D, Tai W, Du L, Im W, Zhang XF.

Abstract:

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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

Jacob F, Pather SR, Huang WK, Wong SZH, Zhou H, Zhang F, Cubitt B, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, de A Torre JC, Ming GL.

Abstract:

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A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

Sun W, McCroskery S, Liu WC, Leist SR, Liu Y, Albrecht RA, Slamanig S, Oliva J, Amanat F, Schaefer A, Dinnon KH, Innis BL, Garcia-Sastre A, Krammer F, Baric RS, Palese P.

Abstract:

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In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19

Br B, Damle H, Ganju S, Damle L.

Abstract:

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Genus-specific pattern of intrinsically disordered central regions in the nucleocapsid protein of coronaviruses

Barik S.

Abstract:

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Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein

Xing Y, Li X, Gao X, Dong Q.

Abstract:

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Wide Diversity of Coronaviruses in Frugivorous and Insectivorous Bat Species: A Pilot Study in Guinea, West Africa

Lacroix A, Vidal N, Keita AK, Thaurignac G, Esteban A, De Nys H, Diallo R, Toure A, Goumou S, Soumah AK, Povogui M, Koivogui J, Monemou JL, Raulino R, Nkuba A, Foulongne V, Delaporte E, Ayouba A, Peeters M.

Abstract:

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Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

Porretta AD, Baggiani A, Arzilli G, Casigliani V, Mariotti T, Mariottini F, Scardina G, Sironi D, Totaro M, Barnini S, Privitera GP.

Abstract:

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Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

Kang YL, Chou YY, Rothlauf PW, Liu Z, Soh TK, Cureton D, Case JB, Chen RE, Diamond MS, Whelan SPJ, Kirchhausen T.

Abstract:

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Genome Sequences of Six SARS-CoV-2 Strains Isolated in Morocco, Obtained Using Oxford Nanopore MinION Technology

Laamarti M, Chemao-Elfihri MW, Kartti S, Laamarti R, Allam L, Ouadghiri M, Smyej I, Rahoui J, Benrahma H, Diawara I, Alouane T, Essabbar A, Siah S, Karra M, El Hafidi N, El Jaoudi R, Sbabou L, Nejjari C, Amzazi S, Mentag R, Belyamani L, Ibrahimi A.

Abstract:

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The D614G substitution in the S gene and clinical information for patients with COVID-19 detected in Hong Kong

Mak GCK, Lau AWL, Chan AMY, Chan DYW, Tsang DNC.

Abstract:

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A systematic review of re-detectable positive virus nucleic acid among COVID-19 patients in recovery phase

Gao Z, Xu Y, Guo Y, Xu D, Zhang L, Wang X, Sun C, Qiu S, Ma K.

Abstract:

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In silico virtual screening, characterization, docking and molecular dynamics studies of crucial SARS-CoV-2 proteins

Alazmi M, Motwalli O.

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In silico investigation of phytoconstituents from Indian medicinal herb 'Tinospora cordifolia (giloy)' against SARS-CoV-2 (COVID-19) by molecular dynamics approach

Chowdhury P.

Abstract:

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Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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Circulating endothelial progenitors are increased in Covid-19 patients and correlate with SARS-CoV-2 RNA in severe cases

Mancuso P, Gidaro A, Gregato G, Raveane A, Cremonesi P, Quarna J, Caccia S, Gusso L, Rusconi S, Giacomelli A, Cogliati C, Bertolini F.

Abstract:

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Potential Zoonotic Origins of SARS-CoV-2 and Insights for Preventing Future Pandemics Through One Health Approach

Konda M, Dodda B, Konala VM, Naramala S, Adapa S.

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Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations

Ortiz-Fern√°ndez L, Sawalha AH.

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Dysregulated adaptive immune response contributes to severe COVID-19

Yu K, He J, Wu Y, Xie B, Liu X, Wei B, Zhou H, Lin B, Zuo Z, Wen W, Xu W, Zou B, Wei L, Huang X, Zhou P.

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Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection

Gand M, Vanneste K, Thomas I, Van Gucht S, Capron A, Herman P, Roosens NHC, De Keersmaecker SCJ.

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Role of cytotoxic T lymphocytes and interferon-γ in coronavirus infection: lessons from murine coronavirus infections in mice

Kyuwa S, Sugiura Y.

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Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

Skendros P, Mitsios A, Chrysanthopoulou A, Mastellos DC, Metallidis S, Rafailidis P, Ntinopoulou M, Sertaridou E, Tsironidou V, Tsigalou C, Tektonidou MG, Konstantinidis T, Papagoras C, Mitroulis I, Germanidis G, Lambris JD, Ritis K.

Abstract:

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Molecules in pathogenesis: angiotensin converting enzyme 2 (ACE2)

Wiese O, Zemlin AE, Pillay TS.

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The importance of cell-mediated immunity in COVID-19 - An opinion

Iqbal H.

Abstract:

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Mevalonate pathway, selenoproteins, redox balance, immune system, Covid-19: Reasoning about connections

Minetti G.

Abstract:

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Cytochrome P450-mediated drug interactions in COVID-19 patients: Current findings and possible mechanisms

El-Ghiaty MA, Shoieb SM, El-Kadi AOS.

Abstract:

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Unique fibrinogen-binding motifs in the nucleocapsid phosphoprotein of SARS CoV-2: Potential implications in host-pathogen interactions

Sangith N.

Abstract:

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COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease

Gan R, Rosoman NP, Henshaw DJE, Noble EP, Georgius P, Sommerfeld N.

Abstract:

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In silico molecular docking analysis for repurposing therapeutics against multiple proteins from SARS-CoV-2

Deshpande RR, Tiwari AP, Nyayanit N, Modak M.

Abstract:

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Management of epigenomic networks entailed in coronavirus infections and COVID-19

El Baba R, Herbein G.

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In silico Potential of Approved Antimalarial Drugs for Repurposing Against COVID-19

Sachdeva C, Wadhwa A, Kumari A, Hussain F, Jha P, Kaushik NK.

Abstract:

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Gold nanoparticles against respiratory diseases: oncogenic and viral pathogens review

V R, Pal K, Zaheer T, Kalarikkal N, Thomas S, de Souza FG, Si A.

Abstract:

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ACE2 isoform diversity predicts the host susceptibility of SARS-CoV-2

Gao S, Luan J, Cui H, Zhang L.

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Intra- and intermolecular atomic-scale interactions in the receptor binding domain of SARS-CoV-2 spike protein: implication for ACE2 receptor binding

Adhikari P, Li N, Shin M, Steinmetz NF, Twarock R, Podgornik R, Ching WY.

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Discovery of sandwich type COVID-19 nucleocapsid protein DNA aptamers

Zhang L, Fang X, Liu X, Ou H, Zhang H, Wang J, Li Q, Cheng H, Zhang W, Luo Z.

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Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain

Bernardi A, Huang Y, Harris B, Xiong Y, Nandi S, McDonald KA, Faller R.

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SARS-CoV-2 jumping the species barrier: zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus

Dhama K, Patel SK, Sharun K, Pathak M, Tiwari R, Yatoo MI, Malik YS, Sah R, Rabaan AA, Panwar PK, Singh KP, Michalak I, Chaicumpa W, Martinez-Pulgarin DF, Bonilla-Aldana DK, Rodriguez-Morales AJ.

Abstract:

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A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2

Liu YM, Shahed-Al-Mahmud M, Chen X, Chen TH, Liao KS, Lo JM, Wu YM, Ho MC, Wu CY, Wong CH, Jan JT, Ma C.

Abstract:

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SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs

Bartoszewski R, Dabrowski M, Jakiela B, Matalon S, Harrod KS, Sanak M, Collawn JF.

Abstract:

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Pathological features of COVID-19 infection from biopsy and autopsy series

Çopur S, Kanbay A, Afşar B, Elsürer Afşar R, Kanbay M.

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SARS-CoV-2 RNA Dependent RNA polymerase (RdRp) - A drug repurposing study

Ahmad J, Ikram S, Ahmad F, Rehman IU, Mushtaq M.

Abstract:

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nCOVID-19 Pandemic: From Molecular Pathogenesis to Potential Investigational Therapeutics

Kabir MT, Uddin MS, Hossain MF, Abdulhakim JA, Alam MA, Ashraf GM, Bungau SG, Bin-Jumah MN, Abdel-Daim MM, Aleya L.

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Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

Choudhary S, Malik YS, Tomar S.

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Pathological Aspects of COVID-19 as a Conformational Disease and the Use of Pharmacological Chaperones as a Potential Therapeutic Strategy

Aoe T.

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Expansion of Single Cell Transcriptomics Data of SARS-CoV Infection in Human Bronchial Epithelial Cells to COVID-19

Zolfaghari Emameh R, Nosrati H, Eftekhari M, Falak R, Khoshmirsafa M.

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Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation

McCallum M, Walls AC, Bowen JE, Corti D, Veesler D.

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In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication

Touret F, Gilles M, Barral K, Nougairède A, van Helden J, Decroly E, de Lamballerie X, Coutard B.

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Expanded Mesenchymal Stem Cells: a novel therapeutic approach of SARS-CoV-2 pneumonia (COVID-19). Concepts regarding a first case in Spain

Soler Rich R, Rius Tarruella J, Melgosa Camarero MT.

Abstract:

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Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein

Singh B.

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Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients

Andres C, Garcia-Cehic D, Gregori J, Piñana M, Rodriguez-Frias F, Guerrero-Murillo M, Esperalba J, Rando A, Goterris L, Codina MG, Quer S, Martín MC, Campins M, Ferrer R, Almirante B, Esteban JI, Pumarola T, Antón A, Quer J.

Abstract:

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Molecular docking, molecular dynamics simulations and reactivity, studies on approved drugs library targeting ACE2 and SARS-CoV-2 binding with ACE2

Khelfaoui H, Harkati D, Saleh BA.

Abstract:

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Food and COVID-19: Preventive/Co-therapeutic Strategies Explored by Current Clinical Trials and in Silico Studies

Di Matteo G, Spano M, Grosso M, Salvo A, Ingallina C, Russo M, Ritieni A, Mannina L.

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An overview of the pathogenic mechanisms involved in severe cases of COVID-19 infection, and the proposal of salicyl-carnosine as a potential drug for its treatment

Lopachev AV, Kazanskaya RB, Khutorova AV, Fedorova TN.

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Insights on 3D Structures of Potential Drug-Targeting Proteins of SARS-CoV-2: Application of Cavity Search and Molecular Docking

Paula FR, Fernandes MS, da Silva FS, Freitas ACSG, de Melo EB, Trossini GHG.

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Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A.

Abstract:

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Cross-Comparison of a Chemiluminescent Platform and a Commercial Receptor Binding Domain-Based ELISA Assay for Detecting SARS-CoV-2 IgG

Antoine-Reid T, Malone J, Maris AS, White-Abell J, Schmitz JE.

Abstract:

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SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease

Perera RAPM, Tso E, Tsang OTY, Tsang DNC, Fung K, Leung YWY, Chin AWH, Chu DKW, Cheng SMS, Poon LLM, Chuang VWM, Peiris M.

Abstract:

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ACE2 and SARS-CoV-2 Infection: Might GLP-1 Receptor Agonists Play a Role?

Monda VM, Porcellati F, Strollo F, Gentile S.

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Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference

Zhang Y, Wang C, Han M, Ye J, Gao Y, Liu Z, He T, Li T, Xu M, Zhou L, Zou G, Lu M, Zhang Z.

Abstract:

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MAIT Cells in COVID-19: Heroes, Villains, or Both?

Haeryfar SMM.

Abstract:

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Novel Coronavirus SARS-CoV-2 Target and Disable Natural Killer Cells: Core Immune Effectors for Fighting the Disease

Jewett A.

Abstract:

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Discovery of Potent SARS-CoV-2 Inhibitors from Approved Antiviral Drugs via Docking Screening

Chtita S, Belhassan A, Aouidate A, Belaidi S, Bouachrine M, Lakhlifi T.

Abstract:

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Visceral adipose tissue in patients with COVID-19: risk stratification for severity

Chandarana H, Dane B, Mikheev A, Taffel MT, Feng Y, Rusinek H.

Abstract:

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Endo-Lysosomal Cation Channels and Infectious Diseases

Chao YK, Chang SY, Grimm C.

Abstract:

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Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

Huang Y, Yang C, Xu XF, Xu W, Liu SW.

Abstract:

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3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO.

Abstract:

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Response to "COVID-19 conundrum: Clinical phenotyping based on pathophysiology as a promising approach to guide therapy in a novel illness" and "Strengthening the foundation of the house of CARDS by phenotyping on the fly" and "COVID-19 phenotypes: leading or misleading?"

Bos LDJ, Sinha P, Dickson RP.

Abstract:

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Pathogenesis of COVID-19-induced ARDS: implications for an aging population

Torres Acosta MA, Singer BD.

Abstract:

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A consideration of publication-derived immune-related associations in Coronavirus and related lung damaging diseases

Geifman N, Whetton AD.

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Potential 'significance' of monoclonal gammopathy of 'undetermined significance' during COVID-19 pandemic

Jain A, Ramasamy K.

Abstract:

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Polyacylated anthocyanins constructively network with catalytic dyad residues of 3CL(pro) of 2019-nCoV than monomeric anthocyanins: A structural-relationship activity study with 10 anthocyanins using in-silico approaches

Khalifa I, Nawaz A, Sobhy R, Althawb SA, Barakat H.

Abstract:

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Genetic comparison among various coronavirus strains for the identification of potential vaccine targets of SARS-CoV2

Kaur N, Singh R, Dar Z, Bijarnia RK, Dhingra N, Kaur T.

Abstract:

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Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: Potential therapeutic targeting

Sharifkashani S, Bafrani MA, Khaboushan AS, Pirzadeh M, Kheirandish A, Yavarpour Bali H, Hessami A, Saghazadeh A, Rezaei N.

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Antibody response against SARS-CoV-2 spike protein and nucleoprotein evaluated by 4 automated immunoassays and 3 ELISAs

Van Elslande J, Decru B, Jonckheere S, Van Wijngaerden E, Houben E, Vandecandelaere P, Indevuyst C, Depypere M, Desmet S, André E, Van Ranst M, Lagrou K, Vermeersch P.

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Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening

Abian O, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Reyburn HT, Rizzuti B, Velazquez-Campoy A.

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Small Particle Aerosol Exposure of African Green Monkeys to MERS-CoV as a Model for Highly Pathogenic Coronavirus Infection

Totura A, Livingston V, Frick O, Dyer D, Nichols D, Nalca A.

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Antibody-based immunotherapeutics and use of convalescent plasma to counter COVID-19: advances and prospects

Sharun K, Tiwari R, Iqbal Yatoo M, Patel SK, Natesan S, Dhama J, Malik YS, Harapan H, Singh RK, Dhama K.

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Auditory Cinchonism in COVID Era

Saniasiaya J, Kulasegarah J.

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COVID-19, Mitochondria, and Interferon

Prasun P.

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COVID-19, Virology and Geroscience: A Perspective

Vellas C, Delobel P, de Souto Barreto P, Izopet J.

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Genetic counseling during COVID-19 pandemic: Tuscany experience

Pagliazzi A, Mancano G, Forzano G, di Giovanni F, Gori G, Traficante G, Iolascon A, Giglio S.

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Application of Bayesian phylogenetic inference modelling for evolutionary genetic analysis and dynamic changes in 2019-nCoV

Shao T, Wang W, Duan M, Pan J, Xin Z, Liu B, Zhou F, Wang G.

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Cell type-specific immune dysregulation in severely ill COVID-19 patients

Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Cerro Chiang G, Kassar AG, Patel N, Green CE, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P.

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Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches

McClain MT, Constantine FJ, Henao R, Liu Y, Tsalik EL, Burke TW, Steinbrink JM, Petzold E, Nicholson BP, Rolfe R, Kraft BD, Kelly MS, Sempowski GD, Denny TN, Ginsburg GS, Woods CW.

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Kinetics and Isotype Assessment of Antibodies Targeting the Spike Protein Receptor Binding Domain of SARS-CoV-2 In COVID-19 Patients as a function of Age and Biological Sex

Graham NR, Whitaker AN, Strother CA, Miles AK, Grier D, McElvany BD, Bruce EA, Poynter ME, Pierce KK, Kirkpatrick BD, Stapleton RD, An G, Botten JW, Crothers JW, Diehl SA.

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Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy

Patterson EI, Elia G, Grassi A, Giordano A, Desario C, Medardo M, Smith SL, Anderson ER, Prince T, Patterson GT, Lorusso E, Lucente MS, Lanave G, Lauzi S, Bonfanti U, Stranieri A, Martella V, Basano FS, Barrs VR, Radford AD, Agrimi U, Hughes GL, Paltrinieri S, Decaro N.

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Elucidation of cryptic and allosteric pockets within the SARS-CoV-2 protease

Sztain T, Amaro R, McCammon JA.

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A deep learning framework for high-throughput mechanism-driven phenotype compound screening

Pham TH, Qiu Y, Zeng J, Xie L, Zhang P.

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Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

Salahudeen AA, Choi SS, Rustagi A, Zhu J, de la O SM, Flynn RA, Margalef-Català M, Santos AJM, Ju J, Batish A, van Unen V, Usui T, Zheng GXY, Edwards CE, Wagar LE, Luca V, Anchang B, Nagendran M, Nguyen K, Hart DJ, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Harbury PB, Glenn JS, Garcia KC, Davis MM, Baric RS, Sabatti C, Amieva MR, Blish CA, Desai TJ, Kuo CJ.

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CoVaccine HT‚Ñ¢ adjuvant potentiates robust immune responses to recombinant SARS-CoV-2 Spike S1 immunisation

Haun BK, Lai CY, Williams CA, Wong TA, Lieberman MM, Pessaint L, Andersen-Elyard H, Lehrer AT.

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The SARS-CoV-2 Spike Variant D614G Favors an Open Conformational State

Mansbach RA, Chakraborty S, Nguyen K, Montefiori D, Korber B, Gnanakaran S.

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Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L.

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Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2

Onabajo OO, Banday AR, Yan W, Obajemu A, Stanifer ML, Santer DM, Florez-Vargas O, Piontkivska H, Vargas J, Kee C, Tyrrell DLJ, Mendoza JL, Boulant S, Prokunina-Olsson L.

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De novo design of modular and tunable allosteric biosensors

Quijano-Rubio A, Yeh HW, Park J, Lee H, Langan RA, Boyken SE, Lajoie MJ, Cao L, Chow CM, Miranda MC, Wi J, Hong HJ, Stewart L, Oh BH, Baker D.

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Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2

Kim J, Mukherjee A, Nelson D, Jozic A, Sahay G.

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Rescue of SARS-CoV-2 from a single bacterial artificial chromosome

Ye C, Chiem K, Park JG, Oladunni F, Platt RN, Anderson T, Almazan F, de la Torre JC, Martinez-Sobrido L.

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Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

Sun W, Leist SR, McCroskery S, Liu Y, Slamanig S, Oliva J, Amanat F, Schaefer A, Dinnon K, Garcia-Sastre A, Krammer F, Baric RS, Palese P.

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Immuno-informatics approach for multi-epitope vaccine designing against SARS-CoV-2

Banerjee S, Majumder K, Gutierrez GJ, Gupta D, Mittal B.

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Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators

Schwarz B, Sharma L, Roberts L, Peng X, Bermejo S, Leighton I, Massana AC, Farhadian S, Ko AI; Yale IMPACT Team, Cruz CSD, Bosio CM.

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Prediction of Small Molecule Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus-2 RNA-dependent RNA Polymerase

Ahmad M, Dwivedy A, Mariadasse R, Tiwari S, Kar D, Jeyakanthan J, Biswal BK.

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RdRp mutations are associated with SARS-CoV-2 genome evolution

Eskier D, Karakülah G, Suner A, Oktay Y.

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Understanding genomic diversity, pan-genome, and evolution of SARS-CoV-2

Parlikar A, Kalia K, Sinha S, Patnaik S, Sharma N, Vemuri SG, Sharma G.

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Associations of viral ribonucleic acid (RNA) shedding patterns with clinical illness and immune responses in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection

Lee PH, Tay WC, Sutjipto S, Fong SW, Ong SWX, Wei WE, Chan YH, Ling LM, Young BE, Toh MPH, Renia L, Ng LF, Leo YS, Lye DC, Lee TH.

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The Loss of Bcl-6 Expressing T Follicular Helper Cells and the Absence of Germinal Centers in COVID-19

Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Li J, Lingwood D, Schmidt AG, Lichterfeld

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SARS-CoV-2 Infection of Ocular Cells from Human Adult Donor Eyes and hESC-Derived Eye Organoids

Makovoz B, Moeller R, Zebitz Eriksen A, tenOever BR, Blenkinsop TA.

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Single-Cell Transcriptomic Analysis of SARS-CoV-2 Reactive CD4 (+) T Cells

Meckiff BJ, Ramírez-Suástegui C, Fajardo V, Chee SJ, Kusnadi A, Simon H, Grifoni A, Pelosi E, Weiskopf D, Sette A, Ay F, Seumois G, Ottensmeier C, Vijayanand P.

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, Olivera de Souza M, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L.

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Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study

Vijayan V, Pant P, Vikram N, Kaur P, Singh TP, Sharma S, Sharma P.

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Identification of potential drug candidates to combat COVID-19: a structural study using the main protease (mpro) of SARS-CoV-2

Sharma P, Vijayan V, Pant P, Sharma M, Vikram N, Kaur P, Singh TP, Sharma S.

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Anthocyanin derivatives as potent inhibitors of SARS-CoV-2 main protease: An in-silico perspective of therapeutic targets against COVID-19 pandemic

Fakhar Z, Faramarzi B, Pacifico S, Faramarzi S.

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Identification of potential anti-TMPRSS2 natural products through homology modelling, virtual screening and molecular dynamics simulation studies

Chikhale RV, Gupta VK, Eldesoky GE, Wabaidur SM, Patil SA, Islam MA.

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In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy

Wei TZ, Wang H, Wu XQ, Lu Y, Guan SH, Dong FQ, Dong CL, Zhu GL, Bao YZ, Zhang J, Wang GY, Li HY.

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Prioritizing potential ACE2 inhibitors in the COVID-19 pandemic: Insights from a molecular mechanics-assisted structure-based virtual screening experiment

Teralı K, Baddal B, Gülcan HO.

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The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach

Morris G, Bortolasci CC, Puri BK, Olive L, Marx W, O'Neil A, Athan E, Carvalho A, Maes M, Walder K, Berk M.

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The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro

Okamoto M, Toyama M, Baba M.

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Approaches and advances in the development of potential therapeutic targets and antiviral agents for the management of SARS-CoV-2 infection

Krishna G, Pillai VS, Veettil MV.

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The SARS-CoV-2 main protease as drug target

Ullrich S, Nitsche C.

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In silico ADMET and molecular docking study on searching potential inhibitors from limonoids and triterpenoids for COVID-19

Vardhan S, Sahoo SK.

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ACE2 Co-evolutionary Pattern Suggests Targets for Pharmaceutical Intervention in the COVID-19 Pandemic

Braun M, Sharon E, Unterman I, Miller M, Shtern AM, Benenson S, Vainstein A, Tabach Y.

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In silico Study of Azithromycin, Chloroquine and Hydroxychloroquine and their Potential Mechanisms of Action against SARS-CoV-2 Infection

Braz HLB, de Moraes Silveira JA, Marinho AD, de Moraes MEA, de Moraes Filho MO, Monteiro HSA, Jorge RJB.

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A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition

Dieterle ME, Haslwanter D, Bortz RH 3rd, Wirchnianski AS, Lasso G, Vergnolle O, Abbasi SA, Fels JM, Laudermilch E, Florez C, Mengotto A, Kimmel D, Malonis RJ, Georgiev G, Quiroz J, Barnhill J, Pirofski LA, Daily JP, Dye JM, Lai JR, Herbert AS, Chandran K, Jangra RK.

Abstract:

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Prospective study comparing deep-throat saliva with other respiratory tract specimens in the diagnosis of novel coronavirus disease (COVID-19)

Lai CKC, Chen Z, Lui G, Ling L, Li T, Wong MCS, Ng RWY, Tso EYK, Ho T, Fung KSC, Ng ST, Wong BKC, Boon SS, Hui DSC, Chan PKS.

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A thermostable, closed SARS-CoV-2 spike protein trimer

Xiong X, Qu K, Ciazynska KA, Hosmillo M, Carter AP, Ebrahimi S, Ke Z, Scheres SHW, Bergamaschi L, Grice GL, Zhang Y; CITIID-NIHR COVID-19 BioResource Collaboration, Nathan JA, Baker S, James LC, Baxendale HE, Goodfellow I, Doffinger R, Briggs JAG.

Abstract:

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Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

Zhou D, Duyvesteyn HME, Chen CP, Huang CG, Chen TH, Shih SR, Lin YC, Cheng CY, Cheng SH, Huang YC, Lin TY, Ma C, Huo J, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Tan TK, Rijal P, Donat RF, Godwin K, Buttigieg KR, Tree JA, Radecke J, Paterson NG, Supasa P, Mongkolsapaya J, Screaton GR, Carroll MW, Gilbert-Jaramillo J, Knight ML, James W, Owens RJ, Naismith JH, Townsend AR, Fry EE, Zhao Y, Ren J, Stuart DI, Huang KA.

Abstract:

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Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe

Malapelle U, Pisapia P, Iaccarino A, Barberis M, Bellevicine C, Brunnström H, de Biase D, De Maglio G, Ericson Lindquist K, Fassan M, Fontanini G, Gruppioni E, Hofman P, Merkelbach-Bruse S, Molina Vila MA, Pujals A, Rapa I, Righi L, Rosell R, Schildgen O, Schildgen V, Schmitt FC, Tallini G, Vander Borght S, Vigliar E, Volante M, Wagener-Ryczek S, Weynand B, Troncone G.

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A modular framework for the development of targeted Covid-19 blood transcript profiling panels

Rinchai D, Syed Ahamed Kabeer B, Toufiq M, Tatari-Calderone Z, Deola S, Brummaier T, Garand M, Branco R, Baldwin N, Alfaki M, Altman MC, Ballestrero A, Bassetti M, Zoppoli G, De Maria A, Tang B, Bedognetti D, Chaussabel D.

Abstract:

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Design of an engineered ACE2 as a novel therapeutics against COVID-19

Payandeh Z, Reza Rahbar M, Jahangiri A, Sadat Hashemi Z, Zakeri A, Jafarisani M, Javad Rasaee M, Khalili S.

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ACE gene polymorphism and severe lung injury in patients with COVID-19

Zheng H, Cao JJ.

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Molecular profiling of immune cell-enriched Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) interacting protein USP13

Süt BB.

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Tackling COVID-19: identification of potential main protease inhibitors via structural analysis, virtual screening, molecular docking and MM-PBSA calculations

Al-Shar'i NA.

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Innate immune evasion by SARS-CoV-2: Comparison with SARS-CoV

Bouayad A.

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Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2

Lee SH, Jee SW, Hwang DY, Kang JK.

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Potential Fast COVID-19 Containment With Trehalose

Martinon D, Borges VF, Gomez AC, Shimada K.

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Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics

Mellors J, Tipton T, Longet S, Carroll M.

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Role of Autophagy in Lung Inflammation

Painter JD, Galle-Treger L, Akbari O.

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Activation and evasion of type I interferon responses by SARS-CoV-2

Lei X, Dong X, Ma R, Wang W, Xiao X, Tian Z, Wang C, Wang Y, Li L, Ren L, Guo F, Zhao Z, Zhou Z, Xiang Z, Wang J.

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NK cells in COVID-19: protectors or opponents?

Alrubayyi A.

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Histopathologic and Autopsy Findings in Patients Diagnosed With Coronavirus Disease 2019 (COVID 19): What we know So Far Based on Correlation With Clinical, Morphologic and Pathobiological Aspects

Al Nemer A.

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Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

Gu H, Chen Q, Yang G, He L, Fan H, Deng YQ, Wang Y, Teng Y, Zhao Z, Cui Y, Li Y, Li XF, Li J, Zhang NN, Yang X, Chen S, Guo Y, Zhao G, Wang X, Luo DY, Wang H, Yang X, Li Y, Han G, He Y, Zhou X, Geng S, Sheng X, Jiang S, Sun S, Qin CF, Zhou Y.

Abstract:

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Genome Sequences of SARS-CoV-2 Strains Detected in Hong Kong

Au CH, Chan WS, Lam HY, Ho DN, Lam SYM, Zee JST, Chan TL, Ma ESK.

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Reports of Coding-Complete Genome Sequences of Five 2019 Novel Coronavirus (SARS-CoV-2) Strains Isolated in Bangladesh

Khan MI, Hasan KN, Sufian A, Hosen MB, Polol MNI, Khaleque MA, Rahman MM, Chowdhury MSM, Haider HU, Razu MH, Khan M, Rabbi MF.

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Vaccine Design from the Ensemble of Surface Glycoprotein Epitopes of SARS-CoV-2: An Immunoinformatics Approach

Rahman N, Ali F, Basharat Z, Shehroz M, Khan MK, Jeandet P, Nepovimova E, Kuca K, Khan H.

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Layer-By-Layer Nanocoating of Antiviral Polysaccharides on Surfaces to Prevent Coronavirus Infections

Otto DP, de Villiers MM.

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Structure-based drug repositioning over the human TMPRSS2 protease domain: search for chemical probes able to repress SARS-CoV-2 Spike protein cleavages

Singh N, Decroly E, Khatib AM, Villoutreix BO.

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The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

Li Q, Wu J, Nie J, Zhang L, Hao H, Liu S, Zhao C, Zhang Q, Liu H, Nie L, Qin H, Wang M, Lu Q, Li X, Sun Q, Liu J, Zhang L, Li X, Huang W, Wang Y.

Abstract:

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Differential Tropism of SARS-CoV and SARS-CoV-2 in Bat Cells

Lau SKP, Wong ACP, Luk HKH, Li KSM, Fung J, He Z, Cheng FKK, Chan TTY, Chu S, Aw-Yong KL, Lau TCK, Fung KSC, Woo PCY.

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Probing 3CL protease: Rationally designed chemical moieties for COVID-19

Sharma M, Prasher P, Mehta M, Zacconi FC, Singh Y, Kapoor DN, Dureja H, Pardhi DM, Tambuwala MM, Gupta G, Chellappan DK, Dua K, Satija S.

Abstract:

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Neuropathogenesis of SARS-CoV-2 infection

Khan S, Gomes J.

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In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

Sinha S, Cheng K, Schäffer AA, Aldape K, Schiff E, Ruppin E.

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Molecular Insights into Small Molecule Drug Discovery for SARS-CoV-2

Su H, Su H, Zhou F, Huang Z, Ma X, Natarajan K, Zhang M, Huang Y.

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Nasopharyngeal Microbiota Profiling of SARS-CoV-2 Infected Patients

De Maio F, Posteraro B, Ponziani FR, Cattani P, Gasbarrini A, Sanguinetti M.

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Performance characteristics of a high throughput automated transcription mediated amplification test for SARS-CoV-2 detection

Pham J, Meyer S, Nguyen C, Williams A, Hunsicker M, McHardy I, Gendlina I, Goldstein DY, Fox AS, Hudson A, Darby P, Hovey P, Morales J, Mitchell J, Harrington K, Majlessi M, Moberly J, Shah A, Worlock A, Walcher M, Eaton B, Getman D, Clark C.

Abstract:

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Phosphodiesterase Inhibitors: Could They Be Beneficial for the Treatment of COVID-19?

Giorgi M, Cardarelli S, Ragusa F, Saliola M, Biagioni S, Poiana G, Naro F, Massimi M.

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A Cell-Based Reporter Assay for Screening Inhibitors of MERS Coronavirus RNA-Dependent RNA Polymerase Activity

Min JS, Kim GW, Kwon S, Jin YH.

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SARS-CoV-2 receptorACE2 protein expression in serum is significantly associated with age

Pavel AB, Wu J, Renert-Yuval Y, Del Duca E, Glickman JW, Miller RL, Paller AS, Krueger JG, Guttman-Yassky E.

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Differences in antibody kinetics and functionality between severe and mild SARS-CoV-2 infections

Rijkers G, Murk JL, Wintermans B, van Looy B, van den Berge M, Veenemans J, Stohr J, Reusken C, van der Pol P, Reimerink J.

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Interplay between SARS-CoV-2 and the type I interferon response

Sa Ribero M, Jouvenet N, Dreux M, Nisole S.

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Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2

Nersisyan S, Shkurnikov M, Turchinovich A, Knyazev E, Tonevitsky A.

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The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing

Xavier J MSc, Giovanetti M PhD, Adelino T MSc, Fonseca V MSc, da Costa AVB BSc, Ribeiro AA BSc, Felicio KN, Duarte CG PhD, Silva MVF PhD, Salgado Á MSc, Lima MT PhD, de Jesus R MSc, Fabri A MSc, Zoboli CFS BSc, Santos TGS, Iani F MSC, Ciccozzi M PhD, de Filippis AMB PhD, de Siqueira MAMT PhD, de Abreu AL MSc, de Azevedo V PhD, Ramalho DB BSc, de Albuquerque CFC MSc, de Oliveira T Phd, Holmes EC PhD, Lourenço J PhD, Alcantara LCJ PhD, Oliveira MAA PhD.

Abstract:

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Bats and humans during the SARS-CoV-2 outbreak: the case of bat-coronavirus from Mexico

Pablo CS, Giovani HC.

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Quantitative determination of mechanical stability in the novel coronavirus spike protein

Moreira RA, Chwastyk M, Baker JL, Guzman HV, Poma AB.

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Neutrophil Extracellular Traps (NETs) and Damage-Associated Molecular Patterns (DAMPs): Two Potential Targets for COVID-19 Treatment

Cicco S, Cicco G, Racanelli V, Vacca A.

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Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

Boni MF, Lemey P, Jiang X, Lam TT, Perry BW, Castoe TA, Rambaut A, Robertson DL.

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Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak

Sekizuka T, Itokawa K, Kageyama T, Saito S, Takayama I, Asanuma H, Nao N, Tanaka R, Hashino M, Takahashi T, Kamiya H, Yamagishi T, Kakimoto K, Suzuki M, Hasegawa H, Wakita T, Kuroda M.

Abstract:

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Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Reveals Mosaic Pattern of Phylogeographical Distribution

Kumar R, Verma H, Singhvi N, Sood U, Gupta V, Singh M, Kumari R, Hira P, Nagar S, Talwar C, Nayyar N, Anand S, Rawat CD, Verma M, Negi RK, Singh Y, Lal R.

Abstract:

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Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection

Moreau GB, Burgess SL, Sturek JM, Donlan AN, Petri WA, Mann BJ.

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The pathophysiology of 'happy' hypoxemia in COVID-19

Dhont S, Derom E, Van Braeckel E, Depuydt P, Lambrecht BN.

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In silico Drug Repurposing for COVID-19: Targeting SARS-CoV-2 Proteins through Docking and Consensus Ranking

Cavasotto C, Di Filippo J.

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In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection

Martorana A, Gentile C, Lauria A.

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Recombinant protein targeting and opsonizing spike glycoprotein for enhancing SARS-CoV-2 phagocytosis

Khattabi L.

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Mechanistic insights of host cell fusion of SARS-CoV-1 and SARS-CoV-2 from atomic resolution structure and membrane dynamics

Chakraborty H, Bhattacharjya S.

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Isolation and phylogenetic analysis of SARS-CoV-2 variants collected in Russia during COVID-19 outbreak

Kozlovskaya L, Piniaeva A, Ignatyev G, Selivanov A, Shishova A, Kovpak A, Gordeychuk I, Ivin Y, Berestovskaya A, Prokhortchouk E, Protsenko D, Rychev M, Ishmukhametov A.

Abstract:

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Computationally Optimized SARS-CoV-2 MHC Class I and II Vaccine Formulations Predicted to Target Human Haplotype Distributions

Liu G, Carter B, Bricken T, Jain S, Viard M, Carrington M, Gifford DK.

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A Computational Approach to Identify Potential Novel Inhibitors against the Coronavirus SARS-CoV-2

Battisti V, Wieder O, Garon A, Seidel T, Urban E, Langer T.

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Relationship Between serum SARS-CoV-2 nucleic acid(RNAemia) and Organ Damage in COVID-19 Patients: A Cohort Study

Xu D, Zhou F, Sun W, Chen L, Lan L, Li H, Xiao F, Li Y, Kolachalama VB, Li Y, Wang X, Xu H.

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In silico study to evaluate the antiviral activity of novel structures against 3C-like protease of Novel Coronavirus (COVID-19) and SARS-CoV

Chunduru K, Sankhe R, Begum F, Sodum N, Kumar N, Kishore A, Shenoy RR, Rao CM, Saravu K.

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Identification of some novel oxazine substituted 9-anilinoacridines as SARS-CoV-2 inhibitors for COVID-19 by molecular docking, free energy calculation and molecular dynamics studies

Rajagopal K, Varakumar P, Aparna B, Byran G, Jupudi S.

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Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA-dependent RNA polymerase (RdRp) inhibition: an in-silico analysis

Singh S, Sk MF, Sonawane A, Kar P, Sadhukhan S.

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Dynamic Changes of Antibodies to SARS-CoV-2 in COVID-19 Patients at Early Stage of Outbreak

Shu H, Wang S, Ruan S, Wang Y, Zhang J, Yuan Y, Liu H, Wu Y, Li R, Pan S, Ouyang Y, Yuan S, Zhou P, Shang Y.

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Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species

Cao Y, Sun Y, Tian X, Bai Z, Gong Y, Qi J, Liu D, Liu W, Li J.

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Current Findings Regarding Natural Components With Potential Anti-2019-nCoV Activity

Zhou J, Huang J.

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Cell-Mediated Immune Responses to COVID-19 Infection

Guihot A, Litvinova E, Autran B, Debré P, Vieillard V.

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Establishing a Unified COVID-19 "Immunome": Integrating Coronavirus Pathogenesis and Host Immunopathology

Wauters E, Thevissen K, Wouters C, Bosisio FM, De Smet F, Gunst J, Humblet-Baron S, Lambrechts D, Liston A, Matthys P, Neyts J, Proost P, Weynand B, Wauters J, Tejpar S, Garg AD.

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Severe Acute Respiratory Syndrome Coronavirus 2: From Gene Structure to Pathogenic Mechanisms and Potential Therapy

Wu J, Yuan X, Wang B, Gu R, Li W, Xiang X, Tang L, Sun H.

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Identification of key interactions between SARS-CoV-2 main protease and inhibitor drug candidates

Yoshino R, Yasuo N, Sekijima M.

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Immune response in COVID-19: A review

Chowdhury MA, Hossain N, Kashem MA, Shahid MA, Alam A.

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Covid-19-Related Endothelial Injury in Lung Cryobiopsy

Ruiz de Gopegui Miguelena P, Peiro Chamarro M, Claraco Vega LM.

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In Silico Identification of a Potent Arsenic Based Approved Drug Darinaparsin against SARS-CoV-2: Inhibitor of RNA Dependent RNA polymerase (RdRp) and Essential Proteases

Chowdhury T, Roymahapatra G, Mandal SM.

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Potential Anti-COVID-19 Therapeutics that Block the Early Stage of the Viral Life Cycle: Structures, Mechanisms, and Clinical Trials

Al-Horani RA, Kar S, Aliter KF.

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Immunogenic SARS-CoV-2 Epitopes: In Silico Study Towards Better Understanding of COVID-19 Disease-Paving the Way for Vaccine Development

Ranga V, Niemelä E, Tamirat MZ, Eriksson JE, Airenne TT, Johnson MS.

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Pt-, Rh-, Ru-, and Cu-Single-Wall Carbon Nanotubes Are Exceptional Candidates for Design of Anti-Viral Surfaces: A Theoretical Study

Aasi A, Aghaei SM, Moore MD, Panchapakesan B.

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Enzymatic Protein Biopolymers as a Tool to Synthetize Eukaryotic Messenger Ribonucleic Acid (mRNA) with Uses in Vaccination, Immunotherapy and Nanotechnology

Urbina F, Morales-Pison S, Maldonado E.

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Longitudinal analyses reveal immunological misfiring in severe COVID-19

Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, Mohanty S, Wang H, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Muenker MC, Fournier JB, Campbell M, Odio CD, Casanovas-Massana A; Yale IMPACT Team, Herbst R, Shaw AC, Medzhitov R, Schulz WL, Grubaugh ND, Dela Cruz C, Farhadian S, Ko AI, Omer SB, Iwasaki A.

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Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy

Mohammad T, Shamsi A, Anwar S, Hussain A, Rehman MT, AlAjmi MF, Islam A, Hassan MI.

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Immunological co-ordination between gut and lungs in SARS-CoV-2 infection

Ahlawat S, Asha, Sharma KK.

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Genomics approaches to synthesis plant-based biomolecules for therapeutic applications to combat SARS-CoV-2

Sharma N, Muthamilarasan M, Prasad A, Prasad M.

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The Lord of the NanoRings: cyclodextrins and the battle against SARS-CoV-2

Garrido PF, Calvelo M, Blanco-González A, Veleiro U, Suárez F, Conde D, Cabezón A, Piñeiro Á, Garcia-Fandino R.

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The Novel Insight of SARS-CoV-2 Molecular Biology and Pathogenesis and Therapeutic Options

Asghari A, Naseri M, Safari H, Saboory E, Parsamanesh N.

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Virtual screening, ADMET prediction and dynamics simulation of potential compounds targeting the main protease of SARS-CoV-2

Yadav R, Imran M, Dhamija P, Chaurasia DK, Handu S.

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Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?

Nawijn MC, Timens W.

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SARS-CoV-2 Whole Genome Amplification and Sequencing for Effective Population-Based Surveillance and Control of Viral Transmission

Harilal D, Ramaswamy S, Loney T, Al Suwaidi H, Khansaheb H, Alkhaja A, Varghese R, Deesi Z, Nowotny N, Alsheikh-Ali A, Tayoun AA.

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Mouse Model of SARS-CoV-2 Reveals Inflammatory Role of Type I Interferon Signaling

Goldman-Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer R, Ring A, Wilen C, Iwasaki A.

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The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2

Di Gioacchino A, Sulc P, Komarova AV, Greenbaum BD, Monasson R, Cocco S.

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Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis

Kumar N, Mishra B, Mehmood A, Athar M, Mukhtar MS.

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Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site

Jaimes J, Millet J, Whittaker G.

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Candidate Targets for Immune Responses to 2019-Novel Coronavirus (nCoV): Sequence Homology- and Bioinformatic-Based Predictions

Grifoni A, Sidney J, Zhang Y, Scheuermann RH, Peters B, Sette A.

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Risks of Zoonotic Transmission of COVID-19 during Eid-Ul-Adha in Pakistan

Mallhi TH, Khan YH, Butt MH, Liaqat A, Abid A, Ahmad A, Misbah S.

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Viral Evolution will Automatically Resolve COVID-19 Pandemic

Sharma D.

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Understanding COVID-19 via comparative analysis of dark proteomes of SARS-CoV-2, human SARS and bat SARS-like coronaviruses

Giri R, Bhardwaj T, Shegane M, Gehi BR, Kumar P, Gadhave K, Oldfield CJ, Uversky VN.

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COVID-19: Critical Role of Angiotensin 1-7 in ACE2 Modulation

Tan CS, Yeoh SF, Long CM.

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Inflammatory Markers in COVID-19

Bhandari S, Sharma S, Bhargava A, Keswani P, Sharma R, Shekhawat A.

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COVID-19: immunopathogenesis and Immunotherapeutics

Yang L, Liu S, Liu J, Zhang Z, Wan X, Huang B, Chen Y, Zhang Y.

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Decoding the proteome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for cell-penetrating peptides involved in pathogenesis or applicable as drug delivery vectors

Hemmati S, Behzadipour Y, Haddad M.

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Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2

Manna S, Baindara P, Mandal SM.

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Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae

Ma Z, Li Z, Dong L, Yang T, Xiao S.

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Interactions Between Remdesivir, Ribavirin, Favipiravir, Galidesivir, Hydroxychloroquine and Chloroquine with Fragment Molecular of the COVID-19 Main Protease with Inhibitor N3 Complex (PDB ID:6LU7) Using Molecular Docking

Silva Arouche TD, Reis AF, Martins AY, S Costa JF, Carvalho Junior RN, J C Neto AM.

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Geogenic arsenic removal through core-shell based functionalized nanoparticles: Groundwater in-situ treatment perspective in the post-COVID anthropocene

Raval NP, Kumar M.

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Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

Amrun SN, Lee CY, Lee B, Fong SW, Young BE, Chee RS, Yeo NK, Torres-Ruesta A, Carissimo G, Poh CM, Chang ZW, Tay MZ, Chan YH, Chen MI, Low JG, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Leo YS, Lye DC, Renia L, Ng LFP.

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Viable SARS-CoV-2 in various specimens from COVID-19 patients

Jeong HW, Kim SM, Kim HS, Kim YI, Kim JH, Cho JY, Kim SH, Kang H, Kim SG, Park SJ, Kim EH, Choi YK.

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Mutations Strengthened SARS-CoV-2 Infectivity

Chen J, Wang R, Wang M, Wei GW.

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Biochemical Dynamics and Clinical Features of Novel Corona Virus (2019-nCoV)

Nazir T, Nazir SUR, Sultana M, Taha N, Riaz H, Islam A, Rasheed Kayani R, Manzoor S.

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Antibody responses to SARS-CoV-2 in healthy individuals returning to Shenzhen

Zhang C, Lin L, Tang D, Liu F, Li M, Li Q, Deng Z, Chu G, Gu D, Dai Y.

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Angiotensin converting enzyme 2 at the interface between renin-angiotensin system inhibition and coronavirus disease 2019

Siri-Angkul N, Chattipakorn SC, Chattipakorn N.

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Preliminary Analysis of B- and T-Cell Responses to SARS-CoV-2

Zhang LX, Miao SY, Qin ZH, Wu JP, Chen HY, Sun HB, Xie Y, Du YQ, Shen J.

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Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

Krafcikova P, Silhan J, Nencka R, Boura E.

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Structural basis of RNA cap modification by SARS-CoV-2

Viswanathan T, Arya S, Chan SH, Qi S, Dai N, Misra A, Park JG, Oladunni F, Kovalskyy D, Hromas RA, Martinez-Sobrido L, Gupta YK.

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A simple solution to prevent microscope eyepiece fogging and spectacle fogging in COVID-19 era

Gurnani B, Kaur K, Mishra K, Venkatesh R.

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Digital eye strain in the era of COVID-19 pandemic: An emerging public health threat

Bhattacharya S, Saleem SM, Singh A.

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From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry

Kanduc D.

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Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm

Fakhouri EW, Peterson SJ, Kothari J, Alex R, Shapiro JI, Abraham NG.

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Defining the CD39/CD73 Axis in SARS-CoV-2 Infection: The CD73(-) Phenotype Identifies Polyfunctional Cytotoxic Lymphocytes

Ahmadi P, Hartjen P, Kohsar M, Kummer S, Schmiedel S, Bockmann JH, Fathi A, Huber S, Haag F, Schulze Zur Wiesch J.

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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK.

Abstract:

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Novel Temperature Trajectory Subphenotypes in COVID-19

Bhavani SV, Huang ES, Verhoef PA, Churpek MM.

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Inducible Epithelial Resistance Against Coronavirus Pneumonia in Mice

Evans SE, Tseng CK, Scott BL, Höök AM, Dickey BF.

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Detection profile of SARS-CoV-2 using RT-PCR in different types of clinical specimens: a systematic review and meta-analysis

Bwire GM, Majigo MV, Njiro BJ, Mawazo A.

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Presence of Genetic Variants Among Young Men With Severe COVID-19

van der Made CI, Simons A, Schuurs-Hoeijmakers J, van den Heuvel G, Mantere T, Kersten S, van Deuren RC, Steehouwer M, van Reijmersdal SV, Jaeger M, Hofste T, Astuti G, Corominas Galbany J, van der Schoot V, van der Hoeven H, Hagmolen Of Ten Have W, Klijn E, van den Meer C, Fiddelaers J, de Mast Q, Bleeker-Rovers CP, Joosten LAB, Yntema HG, Gilissen C, Nelen M, van der Meer JWM, Brunner HG, Netea MG, van de Veerdonk FL, Hoischen A.

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Molecular docking and dynamics study of natural compound for potential inhibition of main protease of SARS-CoV-2

Mahmud S, Uddin MAR, Zaman M, Sujon KM, Rahman ME, Shehab MN, Islam A, Alom MW, Amin A, Akash AS, Saleh MA.

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Identification of a potential SARS-CoV2 inhibitor via molecular dynamics simulations and amino acid decomposition analysis

Razzaghi-Asl N, Ebadi A, Shahabipour S, Gholamin D.

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In-Silico approach for identification of effective and stable inhibitors for COVID-19 main protease (M(pro)) from flavonoid based phytochemical constituents of Calendula officinalis

Das P, Majumder R, Mandal M, Basak P.

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Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors

Fiorucci D, Milletti E, Orofino F, Brizzi A, Mugnaini C, Corelli F.

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Collection and disinfection of forensic biological specimens in five cases concerning COVID-19 in Guangzhou, China

Yang X, Xu Q, Liu H, Xu J, Yang D, Xiao C, Hu H, Liu Y, Liu C.

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A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction

Tan CW, Chia WN, Qin X, Liu P, Chen MI, Tiu C, Hu Z, Chen VC, Young BE, Sia WR, Tan YJ, Foo R, Yi Y, Lye DC, Anderson DE, Wang LF.

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Human SARS-CoV-2 has evolved to reduce CG dinucleotide in its open reading frames

Wang Y, Mao JM, Wang GD, Luo ZP, Yang L, Yao Q, Chen KP.

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Can Dietary Fatty Acids Affect the COVID-19 Infection Outcome in Vulnerable Populations?

Onishi JC, Häggblom MM, Shapses SA.

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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, Le KC, Wrapp D, Lee AG, Liu Y, Chou CW, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Park J, Wang N, Amengor D, Lavinder JJ, Ippolito GC, Maynard JA, Finkelstein IJ, McLellan JS.

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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E.

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Perforin gene variant A91V in young patients with severe COVID-19

Cabrera-Marante O, Rodríguez de Frías E, Pleguezuelo DE, Allende LM, Serrano A, Laguna-Goya R, Mancebo ME, Talayero P, Álvarez-Vallina L, Morales P, Castro-Panete MJ, Paz-Artal E.

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Genetic variants that influence SARS-CoV-2 receptor TMPRSS2 expression among population cohorts from multiple continents

Irham LM, Chou WH, Calkins MJ, Adikusuma W, Hsieh SL, Chang WC.

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Efficient production of recombinant SARS-CoV-2 spike protein using the baculovirus-silkworm system

Fujita R, Hino M, Ebihara T, Nagasato T, Masuda A, Lee JM, Fujii T, Mon H, Kakino K, Nagai R, Tanaka M, Tonooka Y, Moriyama T, Kusakabe T.

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Proteasome activator PA28γ-dependent degradation of coronavirus disease (COVID-19) nucleocapsid protein

Zhang H, Tu J, Cao C, Yang T, Gao L.

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B cell clonal expansion and convergent antibody responses to SARS-CoV-2

Nielsen SCA, Yang F, Hoh RA, Jackson KJL, Roeltgen K, Lee JY, Rustagi A, Rogers AJ, Powell AE, Kim PS, Wang TT, Pinsky B, Blish CA, Boyd SD.

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Potentially repurposable drugs for COVID-19 identified from SARS-CoV-2 Host Protein Interactome

Karunakaran KB, Balakrishnan N, Ganapathiraju M.

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In silico Drug Repurposing to combat COVID-19 based on Pharmacogenomics of Patient Transcriptomic Data

Das S, Camphausen K, Shankavaram U.

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The COVID-19 Gene and Drug Set Library

Kuleshov MV, Clarke DJB, Kropiwnicki E, Jagodnik KM, Bartal A, Evangelista JE, Zhou A, Ferguson LB, Lachmann A, Ma'ayan A.

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SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyper-activation

Yan B, Freiwald T, Chauss D, Wang L, West E, Bibby J, Olson M, Kordasti S, Portilla D, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M.

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Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride

Xiao Q, Wang L, Supekar S, Shen T, Liu H, Ye F, Huang J, Fan H, Wei Z, Zhang C.

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Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis

Maremanda KP, Sundar IK, Li D, Rahman I.

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COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, Miorin L, Olmo EMD, Alon A, Delaforge E, Hennecker CD, Wang G, Pottel J, Bona R, Smith N, Hall JM, Shapiro G, Clark H, Mittermaier A, Kruse AC, García-Sastre A, Roth BL, Glasspool-Malone J, Francone V, Hertzog N, Fremont-Smith M, Ricke DO.

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Can Hyperperfusion of Nonaerated Lung Explain COVID-19 Hypoxia?

Herrmann J, Mori V, Bates JHT, Suki B.

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Interactome of SARS-CoV-2 / nCoV19 modulated host proteins with computationally predicted PPIs

Karunakaran KB, Balakrishnan N, Ganapathiraju MK.

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An in-silico approach to develop of a multi-epitope vaccine candidate against SARS-CoV-2 envelope (E) protein

Ghafouri F, Cohan RA, Noorbakhsh F, Samimi H, Haghpanah V.

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Intermolecular interaction among Remdesivir, RNA and RNA-dependent RNA polymerase of SARS-CoV-2 analyzed by fragment molecular orbital calculation

Kato K, Honma T, Fukuzawa K.

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Comparison of serologic and molecular SARS-CoV 2 results in a large cohort in Southern Tuscany demonstrates a role for serologic testing to increase diagnostic sensitivity

Pancrazzi A, Magliocca P, Lorubbio M, Vaggelli G, Galano A, Mafucci M, Duranti D, Cortesi M, Mazzeschi E, Fabbroni S, Viti G, Tartaglia Polcini A, Tripodo E, Sanchini P, Gervino S, Tacconi D, Dei S, Mazzierli M, D'Urso A, Ognibene A.

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Virological surveillance of SARS-CoV-2 in an Italian northern area: comparison of Real Time RT PCR cycle threshold (Ct) values in three epidemic periods

Veronesi L, Colucci ME, Pasquarella C, Caruso L, Mohieldin Mahgoub Ibrahim M, Zoni R, Pergreffi M, Arcuri C, Seidenari C, Viani I, Capobianco E, Mezzetta S, Affanni P.

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Emergence of European and North American mutant variants of SARS-CoV-2 in Southeast Asia

Islam OK, Al-Emran HM, Hasan MS, Anwar A, Jahid MIK, Hossain MA.

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Surveillance for Probable COVID-19 using Structured Data in the Electronic Medical Record

Burke PC, Shirley RB, Faiman M, Boose EW, Jones RW, Merlino A, Gordon SM, Fraser TG.

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Monoclonal antibodies for the S2 subunit of spike of SARS-CoV-1 cross-react with the newly-emerged SARS-CoV-2

Zheng Z, Monteil VM, Maurer-Stroh S, Yew CW, Leong C, Mohd-Ismail NK, Cheyyatraivendran Arularasu S, Chow VTK, Lin RTP, Mirazimi A, Hong W, Tan YJ.

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Clock genes may drive seasonal variation in SARS-CoV-2 infectivity: are we due for a second wave of COVID-19 in the fall?

Goren A, Wambier CG, McCoy J, Shapiro J, Vaño-Galván S, Herrera S, Glode LM.

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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris M, Wu NC, Nourmohammad A, Mok CKP.

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Cold sensitivity of the SARS-CoV-2 spike ectodomain

Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Gobeil SMC, Janowska K, Li D, Lu X, Deyton M, Sprenz J, Williams W, Saunders K, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P.

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Single-nucleotide conservation state annotation of SARS-CoV-2 genome

Kwon SB, Ernst J.

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Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

Wang B, Asarnow D, Lee WH, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Hu Y, Seah SGK, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI.

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Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies

Davies JP, Almasy KM, McDonald EF, Plate L.

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Prophylactic and Therapeutic Inhibition of In Vitro SARS-CoV-2 Replication by Oleandrin

Plante KS, Plante JA, Fernandez D, Mirchandani D, Bopp N, Aguilar PV, Sastry KJ, Newman RA, Weaver SC.

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Targeting heparan sulfate proteoglycan-assisted endocytosis as a COVID-19 therapeutic option

Zhang Q, Chen CZ, Swaroop M, Xu M, Wang L, Lee J, Pradhan M, Shen M, Luo Z, Xu Y, Huang W, Zheng W, Ye Y.

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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris JSM, Wu NC, Nourmohammad A, Mok CKP.

Abstract:

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Remote Virtual Spinal Evaluation in the Era of COVID-19

Yoon JW, Welch RL, Alamin T, Lavelle WF, Cheng I, Perez-Cruet M, Fielding LC, Sasso RC, Linovitz RJ, Kim KD, Welch WC.

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SARS-CoV-2 genomic variations associated with mortality rate of COVID-19

Toyoshima Y, Nemoto K, Matsumoto S, Nakamura Y, Kiyotani K.

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Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Cauchois R, Koubi M, Delarbre D, Manet C, Carvelli J, Blasco VB, Jean R, Fouche L, Bornet C, Pauly V, Mazodier K, Pestre V, Jarrot PA, Dinarello CA, Kaplanski G.

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Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures

Vanderheiden A, Ralfs P, Chirkova T, Upadhyay AA, Zimmerman MG, Bedoya S, Aoued H, Tharp GM, Pellegrini KL, Manfredi C, Sorscher E, Mainou B, Lobby JL, Kohlmeier JE, Lowen AC, Shi PY, Menachery VD, Anderson LJ, Grakoui A, Bosinger SE, Suthar MS.

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Mesenchymal stem cells: current clinical progress in ARDS and COVID-19

Xiao K, Hou F, Huang X, Li B, Qian ZR, Xie L.

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Targeting SARS-CoV-2 spike protein of COVID-19 with naturally occurring phytochemicals: an in silico study for drug development

Pandey P, Rane JS, Chatterjee A, Kumar A, Khan R, Prakash A, Ray S.

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Self-Amplifying RNA Viruses as RNA Vaccines

Lundstrom K.

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Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters

Osterrieder N, Bertzbach LD, Dietert K, Abdelgawad A, Vladimirova D, Kunec D, Hoffmann D, Beer M, Gruber AD, Trimpert J.

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Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear

Grubaugh ND, Hanage WP, Rasmussen AL.

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Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, Hengartner N, Giorgi EE, Bhattacharya T, Foley B, Hastie KM, Parker MD, Partridge DG, Evans CM, Freeman TM, de Silva TI; Sheffield COVID-19 Genomics Group, McDanal C, Perez LG, Tang H, Moon-Walker A, Whelan SP, LaBranche CC, Saphire EO, Montefiori DC.

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Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data

Chakraborti S, Bheemireddy S, Srinivasan N.

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Paper spray mass spectrometry utilizing Teslin® substrate for rapid detection of lipid metabolite changes during COVID-19 infection

De Silva IW, Nayek S, Singh V, Reddy J, Granger JK, Verbeck GF.

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[Discussion and prospect of infusion of NK cells in the treatment of SARS-CoV-2 infection]

Fan X, Wang S, Wu B, Cai C, Zhang J, Li Y, Meng Y.

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Antimalarial-agent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV-2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19

Sehailia M, Chemat S.

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Comparative molecular investigation of the potential inhibitors against SARS-CoV-2 main protease: a molecular docking study

Khan MA, Mahmud S, Alam ASMRU, Rahman ME, Ahmed F, Rahmatullah M.

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The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections

Machhi J, Herskovitz J, Senan AM, Dutta D, Nath B, Oleynikov MD, Blomberg WR, Meigs DD, Hasan M, Patel M, Kline P, Chang RC, Chang L, Gendelman HE, Kevadiya BD.

Abstract:

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Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies

Ragia G, Manolopoulos VG.

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Protective Immunity against SARS Subunit Vaccine Candidates Based on Spike Protein: Lessons for Coronavirus Vaccine Development

Khalaj-Hedayati A.

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GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune Response

Rudd CE.

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Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19

Carter-Timofte ME, J√∏rgensen SE, Freytag MR, Thomsen MM, Brinck Andersen NS, Al-Mousawi A, Hait AS, Mogensen TH.

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Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host

Ahmed SSSJ, Paramasivam P, Raj K, Kumar V, Murugesan R, Ramakrishnan V.

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Comments to: A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression

Parra-Medina R, Herrera S, Mejía J.

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The Two Sides of Cytopathology during the COVID-19 Health Emergency: Screening versus Diagnosis

Pisapia P, Troncone G.

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Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

Su YCF, Anderson DE, Young BE, Linster M, Zhu F, Jayakumar J, Zhuang Y, Kalimuddin S, Low JGH, Tan CW, Chia WN, Mak TM, Octavia S, Chavatte JM, Lee RTC, Pada S, Tan SY, Sun L, Yan GZ, Maurer-Stroh S, Mendenhall IH, Leo YS, Lye DC, Wang LF, Smith GJD.

Abstract:

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Current Trends and Future Approaches in Small-Molecule Therapeutics for COVID-19

Laws M, Surani YM, Hasan MM, Chen Y, Jin P, AlAdhami T, Chowdhury M, Imran A, Psaltis I, Jamshidi S, Nahar KS, Rahman KM.

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Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses

Nebigil CG, Moog C, Vagner S, Benkirane-Jessel N, Smith DR, Désaubry L.

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A molecular docking study revealed that synthetic peptides induced conformational changes in the structure of SARS-CoV-2 spike glycoprotein, disrupting the interaction with human ACE2 receptor

Souza PFN, Lopes FES, Amaral JL, Freitas CDT, Oliveira JTA.

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COVID-19 Docking Server: A meta server for docking small molecules, peptides and antibodies against potential targets of COVID-19

Kong R, Yang G, Xue R, Liu M, Wang F, Hu J, Guo X, Chang S.

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Multiplex reverse transcription loop-mediated isothermal amplification combined with nanoparticle-based lateral flow biosensor for the diagnosis of COVID-19

Zhu X, Wang X, Han L, Chen T, Wang L, Li H, Li S, He L, Fu X, Chen S, Xing M, Chen H, Wang Y.

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Speech-Language Pathology Management for Adults With COVID-19 in the Acute Hospital Setting: Initial Recommendations to Guide Clinical Practice

Namasivayam-MacDonald AM, Riquelme LF.

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Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

Schmidt F, Weisblum Y, Muecksch F, Hoffmann HH, Michailidis E, Lorenzi JCC, Mendoza P, Rutkowska M, Bednarski E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, Caskey M, Robbiani DF, Nussenzweig MC, Rice CM, Hatziioannou T, Bieniasz PD.

Abstract:

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Virtual screening, molecular dynamics and structure-activity relationship studies to identify potent approved drugs for Covid-19 treatment

Rahman MM, Saha T, Islam KJ, Suman RH, Biswas S, Rahat EU, Hossen MR, Islam R, Hossain MN, Mamun AA, Khan M, Ali MA, Halim MA.

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Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19

Chien M, Anderson TK, Jockusch S, Tao C, Li X, Kumar S, Russo JJ, Kirchdoerfer RN, Ju J.

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ACE2, TMPRSS2, and Furin variants and SARS-CoV-2 infection in Madrid, Spain

Torre-Fuentes L, Matías-Guiu J, Hernández-Lorenzo L, Montero-Escribano P, Pytel V, Porta-Etessam J, Gómez-Pinedo U, Matías-Guiu JA.

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Natural derivatives with dual binding potential against SARS-CoV-2 main protease and human ACE2 possess low oral bioavailability: a brief computational analysis

Sharma P, Shanavas A.

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Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells

Appelberg S, Gupta S, Akusjärvi SS, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, Krishnan S, Singh K, Penninger JM, Mirazimi A, Neogi U.

Abstract:

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Cyanobacterial metabolites as promising drug leads against the M(pro) and PL(pro) of SARS-CoV-2: an in silico analysis

Naidoo D, Roy A, Kar P, Mutanda T, Anandraj A.

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The antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds - Additional weapons in the fight against the COVID-19 pandemic?

Fuzimoto AD, Isidoro C.

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COVID-19 infection: mitohormetic concept of immune response

Gebicki J, Wieczorkowska M.

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An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Heydenburg Fuller D.

Abstract:

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Regarding pandemics: Ibn Jatima from Almería anticipates the physiopathological concept of multi-organ failure in the 14th century

Herrera Carranza M.

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Biological, clinical and epidemiological features of COVID-19, SARS and MERS and AutoDock simulation of ACE2

Zhang XY, Huang HJ, Zhuang DL, Nasser MI, Yang MH, Zhu P, Zhao MY.

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Immune Responses to the Novel Coronavirus-2: Friend or Foe?

Mahmoodpoor A, Nader ND.

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Neuropathogenic human coronaviruses: A review

Abdelaziz OS, Waffa Z.

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Structure-based virtual screening to discover potential lead molecules for the SARS-CoV-2 main protease

Gahlawat A, Kumar N, Kumar R, Sandhu H, Singh IP, Singh S, Sjöstedt A, Garg P.

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Distribution of SARS-CoV-2 PCR Cycle Threshold Values Provide Practical Insight Into Overall and Target-Specific Sensitivity Among Symptomatic Patients

Buchan BW, Hoff JS, Gmehlin CG, Perez A, Faron ML, Munoz-Price LS, Ledeboer NA.

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Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants

Fatoki TH, Ibraheem O, Ogunyemi IO, Akinmoladun AC, Ugboko HU, Adeseko CJ, Awofisayo OA, Olusegun SJ, Enibukun JM.

Abstract:

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SARS-CoV-2 encoded proteome and human genetics: from interaction-based to ribosomal biology impact on disease and risk processes

Sirpilla O, Bauss J, Gupta R, Underwood A, Qutob D, Freeland T, Bupp C, Carcillo J, Hartog N, Rajasekaran S, Prokop JW.

Abstract:

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Epigenetic mechanisms regulating COVID-19 infection

Chlamydas S, Papavassiliou AG, Piperi C.

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Novel coronavirus SARS-CoV-2 (Covid-19) dynamics inside the human body

Saha A, Saha B.

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FoldRec-C2C: protein fold recognition by combining cluster-to-cluster model and protein similarity network

Shao J, Yan K, Liu B.

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Identification of COVID-19 Infection-Related Human Genes Based on a Random Walk Model in a Virus-Human Protein Interaction Network

Zhang Y, Zeng T, Chen L, Ding S, Huang T, Cai YD.

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Identification of novel mutations in RNA-dependent RNA polymerases of SARS-CoV-2 and their implications on its protein structure

Chand GB, Banerjee A, Azad GK.

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The Future of Pathology: What can we Learn from the COVID-19 Pandemic?

Williams BJ, Fraggetta F, Hanna MG, Huang R, Lennerz J, Salgado R, Sirintrapun SJ, Pantanowitz L, Parwani A, Zarella M, Treanor DE.

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Comparison five primer sets from different genome region of COVID-19 for detection of virus infection by conventional RT-PCR

Mollaei HR, Afshar AA, Kalantar-Neyestanaki D, Fazlalipour M, Aflatoonian B.

Abstract:

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In-silico drug repurposing and molecular dynamics puzzled out potential SARS-CoV-2 main protease inhibitors

Ibrahim MAA, Abdelrahman AHM, Hegazy MF.

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Targeting virus-host interaction by novel pyrimidine derivative: an in silico approach towards discovery of potential drug against COVID-19

Rane JS, Pandey P, Chatterjee A, Khan R, Kumar A, Prakash A, Ray S.

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Dysfunction of adaptive immunity is related to severity of COVID-19: a retrospective study

Xie L, Wu Q, Lin Q, Liu X, Lin W, Hao S, Hu W, Xiang G, Lu H, Li S.

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Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Noorimotlagh Z, Karami C, Mirzaee SA, Kaffashian M, Mami S, Azizi M.

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Immuno-pathogenesis of nCOVID-19 and a possible host-directed therapy including anti-inflammatory and anti-viral prostaglandin (PG J(2)) for effective treatment and reduction in the death toll

Shahzad S, Willcox M.

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Virology, pathogenesis, diagnosis and in-line treatment of COVID-19

Samudrala PK, Kumar P, Choudhary K, Thakur N, Wadekar GS, Dayaramani R, Agrawal M, Alexander A.

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Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series

Bradley BT, Maioli H, Johnston R, Chaudhry I, Fink SL, Xu H, Najafian B, Deutsch G, Lacy JM, Williams T, Yarid N, Marshall DA.

Abstract:

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Blocking IL-1 to prevent respiratory failure in COVID-19

van de Veerdonk FL, Netea MG.

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Covid-19 infection and the host genetic predisposition: does it exist?

Vašků A.

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Design of a Multi-epitope Vaccine against SARS-CoV-2 using Immunoinformatics approach

Sanami S, Zandi M, Pourhossein B, Mobini GR, Safaei M, Abed A, Arvejeh PM, Chermahini FA, Alizadeh M.

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SARS-CoV-2 replicating in non-primate mammalian cells probably have critical advantages for COVID-19 vaccines due to anti-Gal antibodies: A minireview and proposals

Chen JM.

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ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

Benetti E, Tita R, Spiga O, Ciolfi A, Birolo G, Bruselles A, Doddato G, Giliberti A, Marconi C, Musacchia F, Pippucci T, Torella A, Trezza A, Valentino F, Baldassarri M, Brusco A, Asselta R, Bruttini M, Furini S, Seri M, Nigro V, Matullo G, Tartaglia M, Mari F; GEN-COVID Multicenter Study, Renieri A, Pinto AM.

Abstract:

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SARS-CoV-2 as a Factor to Disbalance the Renin-Angiotensin System: A Suspect in the Case of Exacerbated IL-6 Production

Franco R, Rivas-Santisteban R, Serrano-Marín J, Rodríguez-Pérez AI, Labandeira-García JL, Navarro G.

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SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection

Altmann DM, Boyton RJ.

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Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T, Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T, Cheng J, Straub JH, Stürzel CM, Fröhlich T, Berninghausen O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R.

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Modelling the inactivation of viruses from the Coronaviridae family in response to temperature and relative humidity in suspensions or surfaces

Guillier L, Martin-Latil S, Chaix E, Thébault A, Pavio N, Le Poder S, Batéjat C, Biot F, Koch L, Schaffner D, Sanaa M; Covid-19 Emergency Collective Expert Appraisal Group.

Abstract:

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Glucose-6-Phosphate Dehydrogenase Deficiency and COVID-19 Infection

Vick DJ.

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Comprehensive Review on Current Interventions, Diagnostic, and Nanotechnology Perspectives against SARS-CoV-2

Chauhan DS, Prasad R, Srivastava R, Jaggi M, Chauhan SC, Yallapu MM.

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SARS-CoV-2 Virologic and Immunologic Correlates in Patients with Olfactory and Taste Disorders

Benazzo M, Cassaniti I, Maiorano E, Calastri A, Novazzi F, Bonetti A, Sarasini A, Bruno R, Baldanti F.

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Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target

Enríquez-Flores S, Flores-López LA, García-Torres I, de la Mora-de la Mora I, Cabrera N, Gutiérrez-Castrellón P, Martínez-Pérez Y, López-Velázquez G.

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Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes

Zettl F, Meister TL, Vollmer T, Fischer B, Steinmann J, Krawczyk A, V'kovski P, Todt D, Steinmann E, Pfaender S, Zimmer G.

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Increased CD95 (Fas) and PD-1 expression in peripheral blood T lymphocytes in COVID-19 patients

Bellesi S, Metafuni E, Hohaus S, Maiolo E, Marchionni F, D'Innocenzo S, La Sorda M, Ferraironi M, Ramundo F, Fantoni M, Murri R, Cingolani A, Sica S, Gasbarrini A, Sanguinetti M, Chiusolo P, De Stefano V.

Abstract:

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Biotin Functionalized Self-Assembled Peptide Nanofiber as an Adjuvant for Immunomodulatory Response

Demircan MB, Tohumeken S, Gunduz N, Khalily MA, Tekinay T, Guler MO, Tekinay AB.

Abstract:

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The «moonlighting protein» able to explain the T(h)1 immune lockdown in severe COVID-19

Roncati L, Lusenti B.

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Application prospect of polysaccharides in the development of anti-novel coronavirus drugs and vaccines

Chen X, Han W, Wang G, Zhao X.

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Performance evaluation of Abbott ARCHITECT SARS-CoV-2 IgG immunoassay in comparison with indirect immunofluorescence and virus microneutralization test

Meschi S, Colavita F, Bordi L, Matusali G, Lapa D, Amendola A, Vairo F, Ippolito G, Capobianchi MR, Castilletti C; INMICovid-19 laboratory team.

Abstract:

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COVID-19: from rapid genome sequencing to fast decisions

Behrmann O, Spiegel M.

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Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

Meredith LW, Hamilton WL, Warne B, Houldcroft CJ, Hosmillo M, Jahun AS, Curran MD, Parmar S, Caller LG, Caddy SL, Khokhar FA, Yakovleva A, Hall G, Feltwell T, Forrest S, Sridhar S, Weekes MP, Baker S, Brown N, Moore E, Popay A, Roddick I, Reacher M, Gouliouris T, Peacock SJ, Dougan G, Török ME, Goodfellow I.

Abstract:

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Lower prevalence of antibodies neutralizing SARS-CoV-2 in group O French blood donors

Gallian P, Pastorino B, Morel P, Chiaroni J, Ninove L, de Lamballerie X.

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In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2

Pizzorno A, Padey B, Dubois J, Julien T, Traversier A, Dulière V, Brun P, Lina B, Rosa-Calatrava M, Terrier O.

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Drug repurposing studies targeting SARS-CoV-2: an ensemble docking approach on drug target 3C-like protease (3CL(pro))

Koulgi S, Jani V, Uppuladinne M, Sonavane U, Nath AK, Darbari H, Joshi R.

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The utility of native MS for understanding the mechanism of action of repurposed therapeutics in COVID-19: heparin as a disruptor of the SARS-CoV-2 interaction with its host cell receptor

Yang Y, Du Y, Kaltashov IA.

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Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

Oude Munnink BB, Nieuwenhuijse DF, Stein M, O'Toole Á, Haverkate M, Mollers M, Kamga SK, Schapendonk C, Pronk M, Lexmond P, van der Linden A, Bestebroer T, Chestakova I, Overmars RJ, van Nieuwkoop S, Molenkamp R, van der Eijk AA, GeurtsvanKessel C, Vennema H, Meijer A, Rambaut A, van Dissel J, Sikkema RS, Timen A, Koopmans M; Dutch-Covid-19 response team.

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Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

Ostaszewski M, Mazein A, Gillespie ME, Kuperstein I, Niarakis A, Hermjakob H, Pico AR, Willighagen EL, Evelo CT, Hasenauer J, Schreiber F, Dräger A, Demir E, Wolkenhauer O, Furlong LI, Barillot E, Dopazo J, Orta-Resendiz A, Messina F, Valencia A, Funahashi A, Kitano H, Auffray C, Balling R, Schneider R.

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Detection and Genetic Characterization of Community-Based SARS-CoV-2 Infections - New York City, March 2020

Bushman D, Alroy KA, Greene SK, Keating P, Wahnich A, Weiss D, Pathela P, Harrison C, Rakeman J, Langley G, Tong S, Tao Y, Uehara A, Queen K, Paden CR, Szymczak W, Orner EP, Nori P, Lai PA, Jacobson JL, Singh HK, Calfee DP, Westblade LF, Vasovic LV, Rand JH, Liu D, Singh V, Burns J, Prasad N; CDC COVID-19 Surge Laboratory Group;, Sell J.

Abstract:

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Designing a multi-epitope vaccine against SARS-CoV-2: an immunoinformatics approach

Samad A, Ahammad F, Nain Z, Alam R, Imon RR, Hasan M, Rahman MS.

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Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19

Dogan M, Kozhaya L, Placek L, Gunter C, Yigit M, Hardy R, Plassmeyer M, Coatney P, Lillard K, Bukhari Z, Kleinberg M, Hayes C, Arditi M, Klapper E, Merin N, Liang BT, Gupta R, Alpan O, Unutmaz D.

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Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators

Schwarz B, Sharma L, Roberts L, Peng X, Bermejo S, Leighton I, Massana AC, Farhadian S, Ko A, DelaCruz C, Bosio CM.

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Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex

Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng ET, Vatandaslar H, Chait B, Kapoor T, Darst SA, Campbell EA.

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Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

Rathnasinghe R, Strohmeier S, Amanat F, Gillespie VL, Krammer F, García-Sastre A, Coughlan L, Schotsaert M, Uccellini M.

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Conserved Genomic Terminals of SARS-CoV-2 as Co-evolving Functional Elements and Potential Therapeutic Targets

Chan AP, Choi Y, Schork NJ.

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SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function

Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, Holtzman MJ, Diamond MS.

Abstract:

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SARS-CoV-2 contributes to altering the post-transcriptional regulatory networks across human tissues by sponging RNA binding proteins and micro-RNAs

Srivastava R, Daulatabad SV, Srivastava M, Janga SC.

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Comprehensive in-vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

Huston NC, Wan H, Araujo Tavares RC, Wilen C, Pyle AM.

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Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis

Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Shrihari S, McCune BT, Harvey IB, Smith B, Keeler SP, Bloyet LM, Winkler ES, Holtzman MJ, Fremont DH, Whelan SPJ, Diamond MS.

Abstract:

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N and O glycosylation of the SARS-CoV-2 spike protein

Sanda M, Morrison L, Goldman R.

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Unique transcriptional changes in coagulation cascade genes in SARS-CoV-2-infected lung epithelial cells: A potential factor in COVID-19 coagulopathies

FitzGerald ES, Jamieson AM.

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Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2

Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Stevens B, Lee JY, Rustagi A, Rogers AJ, Powell AE, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Chang HY, Satpathy AT, Jardetzky TS, Kim PS, Wang TT, Pinsky BA, Blish CA, Boyd SD.

Abstract:

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Which animals are at risk? Predicting species susceptibility to Covid-19

Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS.

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Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3

Virdi RS, Bavisotto RV, Hopper NC, Frick DN.

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A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

Zhou Y, Hou Y, Shen J, Kallianpur A, Zein J, Culver DA, Farha S, Comhair S, Fiocchi C, Gack MU, Mehra R, Stappenbeck T, Chan T, Eng C, Jung JU, Jehi L, Erzurum S, Cheng F.

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Insights into Potential Mechanisms of Injury and Treatment Targets in COVID-19, SARS-Cov-2 Infection

Zhyvotovska A, Yusupov D, Foronjy R, Nakeshbandi M, McFarlane SI, Salifu M.

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GPU-Accelerated Drug Discovery with Docking on the Summit Supercomputer: Porting, Optimization, and Application to COVID-19 Research

LeGrand S, Scheinberg A, Tillack AF, Thavappiragasam M, Vermaas JV, Agarwal R, Larkin J, Poole D, Santos-Martins D, Solis-Vasquez L, Koch A, Forli S, Hernandez O, Smith JC, Sedova A.

Abstract:

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ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19

Bao R, Hernandez K, Huang L, Luke JJ.

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Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

Aguiar JA, Tremblay BJ, Mansfield MJ, Woody O, Lobb B, Banerjee A, Chandiramohan A, Tiessen N, Cao Q, Dvorkin-Gheva A, Revill S, Miller MS, Carlsten C, Organ L, Joseph C, John A, Hanson P, Austin R, McManus BM, Jenkins G, Mossman K, Ask K, Doxey AC, Hirota JA.

Abstract:

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Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

Kreer C, Zehner M, Weber T, Ercanoglu MS, Gieselmann L, Rohde C, Halwe S, Korenkov M, Schommers P, Vanshylla K, Di Cristanziano V, Janicki H, Brinker R, Ashurov A, Krähling V, Kupke A, Cohen-Dvashi H, Koch M, Eckert JM, Lederer S, Pfeifer N, Wolf T, Vehreschild MJGT, Wendtner C, Diskin R, Gruell H, Becker S, Klein F.

Abstract:

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Rapid Gel Card Agglutination Assays for Serological Analysis Following SARS-CoV-2 Infection in Humans

Alves D, Curvello R, Henderson E, Kesarwani V, Walker JA, Leguizamon SC, McLiesh H, Raghuwanshi VS, Samadian H, Wood EM, McQuilten ZK, Graham M, Wieringa M, Korman TM, Scott TF, Banaszak Holl MM, Garnier G, Corrie SR.

Abstract:

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Excess soluble fms-like tyrosine kinase 1 correlates with endothelial dysfunction and organ failure in critically ill COVID-19 patients

Dupont V, Kanagaratnam L, Goury A, Poitevin G, Bard M, Julien G, Bonnivard M, Champenois V, Noel V, Mourvillier B, Nguyen P.

Abstract:

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Computer-aided screening for potential TMPRSS2 inhibitors: a combination of pharmacophore modeling, molecular docking and molecular dynamics simulation approaches

Idris MO, Yekeen AA, Alakanse OS, Durojaye OA.

Abstract:

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Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics

VanPatten S, He M, Altiti A, F Cheng K, Ghanem MH, Al-Abed Y.

Abstract:

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Targeting zinc metalloenzymes in COVID-19

Doboszewska U, Wlaź P, Nowak G, Młyniec K.

Abstract:

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Induced Cardiovascular Syndrome: Etiology, Outcomes, and Management

Turshudzhyan A.

Abstract:

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Focusing On A Unique Innate Memory Cell Population Of Natural Killer Cells In The Fight Against COVID-19: Harnessing The Ubiquity Of Cytomegalovirus Exposure

Jaiswal SR, Malhotra P, Mitra DK, Chakrabarti S.

Abstract:

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Immune and Metabolic Signatures of COVID-19 Revealed by Transcriptomics Data Reuse

Gardinassi LG, Souza COS, Sales-Campos H, Fonseca SG.

Abstract:

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Severe COVID-19: NLRP3 Inflammasome Dysregulated

van den Berg DF, Te Velde AA.

Abstract:

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Battling COVID-19 Pandemic: Sphingosine-1-Phosphate Analogs as an Adjunctive Therapy?

Naz F, Arish M.

Abstract:

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MicroGMT: A Mutation Tracker for SARS-CoV-2 and Other Microbial Genome Sequences

Xing Y, Li X, Gao X, Dong Q.

Abstract:

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A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

Rambaut A, Holmes EC, O'Toole Á, Hill V, McCrone JT, Ruis C, du Plessis L, Pybus OG.

Abstract:

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Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

Mathew D, Giles JR, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Ramage H, Cherry S, Hensley SE, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit, Betts MR, Meyer NJ, Wherry EJ.

Abstract:

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Comprehensive mapping of immune perturbations associated with severe COVID-19

Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum RS, Mathew D, Baxter AE, Vella LA, Kuthuru O, Apostolidis SA, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR.

Abstract:

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Discovery of M Protease inhibitors encoded by SARS-CoV-2

Hung HC, Ke YY, Huang SY, Huang PN, Kung YA, Chang TY, Yen KJ, Peng TT, Chang SE, Huang CT, Tsai YR, Wu SH, Lee SJ, Lin JH, Liu BS, Sung WC, Shih SR, Chen CT, Hsu JT.

Abstract:

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Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs

Zhong LLD, Lam WC, Yang W, Chan KW, Sze SCW, Miao J, Yung KKL, Bian Z, Wong VT.

Abstract:

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COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks

Blaess M, Kaiser L, Sauer M, Csuk R, Deigner HP.

Abstract:

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High Throughput Virtual Screening to Discover Inhibitors of the Main Protease of the Coronavirus SARS-CoV-2

Olubiyi OO, Olagunju M, Keutmann M, Loschwitz J, Strodel B.

Abstract:

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Mutational Frequencies of SARS-CoV-2 Genome during the Beginning Months of the Outbreak in USA

Kaushal N, Gupta Y, Goyal M, Khaiboullina SF, Baranwal M, Verma SC.

Abstract:

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[Genetic and epigenetic variability, and the Covid-19 pandemic]

Rivera-Silva G.

Abstract:

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COVID-19: An Immunopathologic Assault

Munro N, Scordo KA, Richmond MM.

Abstract:

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SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

Le Bert N, Tan AT, Kunasegaran K, Tham CYL, Hafezi M, Chia A, Chng MHY, Lin M, Tan N, Linster M, Chia WN, Chen MI, Wang LF, Ooi EE, Kalimuddin S, Tambyah PA, Low JG, Tan YJ, Bertoletti A.

Abstract:

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Potently neutralizing and protective human antibodies against SARS-CoV-2

Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.

Abstract:

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A Molecular Docking Study Repurposes FDA Approved Iron Oxide Nanoparticles to Treat and Control COVID-19 Infection

Abo-Zeid Y, Ismail NS, McLean GR, Hamdy NM.

Abstract:

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Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection

Wan J, Xing S, Ding L, Wang Y, Gu C, Wu Y, Rong B, Li C, Wang S, Chen K, He C, Zhu D, Yuan S, Qiu C, Zhao C, Nie L, Gao Z, Jiao J, Zhang X, Wang X, Ying T, Wang H, Xie Y, Lu Y, Xu J, Lan F.

Abstract:

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Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease

Schultheiß C, Paschold L, Simnica D, Mohme M, Willscher E, von Wenserski L, Scholz R, Wieters I, Dahlke C, Tolosa E, Sedding DG, Ciesek S, Addo M, Binder M.

Abstract:

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SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters

Zhang AJ, Lee AC, Chu H, Chan JF, Fan Z, Li C, Liu F, Chen Y, Yuan S, Poon VK, Chan CC, Cai JP, Wu KL, Sridhar S, Chan YS, Yuen KY.

Abstract:

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Transcriptome-based drug repositioning for coronavirus disease 2019 (COVID-19)

Jia Z, Song X, Shi J, Wang W, He K.

Abstract:

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Trained innate immunity, COVID-19 therapeutic dilemma, and fake science

Beliz√°rio JE.

Abstract:

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Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies

Mishra SS, Ranjan S, Sharma CS, Singh HP, Kalra S, Kumar N.

Abstract:

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The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19

Bosso M, Thanaraj TA, Abu-Farha M, Alanbaei M, Abubaker J, Al-Mulla F.

Abstract:

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SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

Jiang HW, Li Y, Zhang HN, Wang W, Yang X, Qi H, Li H, Men D, Zhou J, Tao SC.

Abstract:

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Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

Sadegh S, Matschinske J, Blumenthal DB, Galindez G, Kacprowski T, List M, Nasirigerdeh R, Oubounyt M, Pichlmair A, Rose TD, Salgado-Albarrán M, Späth J, Stukalov A, Wenke NK, Yuan K, Pauling JK, Baumbach J.

Abstract:

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The spectrum of pathological findings in coronavirus disease (COVID-19) and the pathogenesis of SARS-CoV-2

Barth RF, Buja LM, Parwani AV.

Abstract:

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New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

Hou Y, Zhao J, Martin W, Kallianpur A, Chung MK, Jehi L, Sharifi N, Erzurum S, Eng C, Cheng F.

Abstract:

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Immunopathogenesis of COVID-19 and early immunomodulators

Lee KY, Rhim JW, Kang JH.

Abstract:

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Effects of Airborne Nanoparticles on the Nervous System: Amyloid Protein Aggregation, Neurodegeneration and Neurodegenerative Diseases

von Mikecz A, Schikowski T.

Abstract:

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Late histological findings in symptomatic COVID-19 patients: A case report

Aiolfi A, Bruni B, Biraghi T, Montisci A, Miceli A, Baronio B, Khor D, Cirri S, Donatelli F, Clemente C, Bona D.

Abstract:

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Reckoning a fungal metabolite, Pyranonigrin A as a potential Main protease (M(pro)) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation

Rao P, Shukla A, Parmar P, Rawal RM, Patel B, Saraf M, Goswami D.

Abstract:

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Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters

Liu Q, Zhao S, Shi CM, Song S, Zhu S, Su Y, Zhao W, Li M, Bao Y, Xue Y, Chen H.

Abstract:

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Single-cell RNA Expression Profiling of ACE2, The Receptor of SARS-CoV-2

Zhao Y, Zhao Z, Wang Y, Zhou Y, Ma Y, Zuo W.

Abstract:

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ACE2, the Receptor that Enables the Infection by SARS-CoV-2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators

Gross LZF, Sacerdoti M, Piiper A, Zeuzem S, Leroux AE, Biondi RM.

Abstract:

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Magnitude and kinetics of anti-SARS-CoV-2 antibody responses and their relationship to disease severity

Lynch KL, Whitman JD, Lacanienta NP, Beckerdite EW, Kastner SA, Shy BR, Goldgof GM, Levine AG, Bapat SP, Stramer SL, Esensten JH, Hightower AW, Bern C, Wu AHB.

Abstract:

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An immunotherapeutic method for COVID-19 patients: a soluble ACE2-Anti-CD16 VHH to block SARS-CoV-2 Spike protein

Sheikhi A, Hojjat-Farsangi M.

Abstract:

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Can the Environmental Phagocyte Acanthamoeba Be a Useful Model to Study SARS-CoV-2 Pathogenicity, Infectivity, and Evasion of Cellular Immune Defenses?

Siddiqui R, Khan NA.

Abstract:

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omputer modelling of a potential agent against SARS-Cov-2 (COVID-19) protease

Lesk AM, Konagurthu AS, Allison L, de la Banda MG, Stuckey PJ, Abramson D.

Abstract:

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Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses

Li R, Wu K, Li Y, Liang X, Lai KP, Chen J.

Abstract:

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Temporal Change of SARS-CoV-2 in Clinical Specimens of COVID-19 Pneumonia Patients

Luvira V, Jittmittraphap A, Muangnoicharoen S, Chantawat N, Janwitthayanan W, Leaungwutiwong P.

Abstract:

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Computational discovery of small drug-like compounds as potential inhibitors of SARS-CoV-2 main protease

Andrianov AM, Kornoushenko YV, Karpenko AD, Bosko IP, Tuzikov AV.

Abstract:

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Mesenchymal Stem Cell Derived Exosomes: a Nano Platform for Therapeutics and Drug Delivery in Combating COVID-19

Pinky, Gupta S, Krishnakumar V, Sharma Y, Dinda AK, Mohanty S.

Abstract:

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Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease

Qiao Z, Zhang H, Ji HF, Chen Q.

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Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development

Wan Q, Song D, Li H, He ML.

Abstract:

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Assessment of risk conferred by coding and regulatory variations of TMPRSS2 and CD26 in susceptibility to SARS-CoV-2 infection in human

Senapati S, Kumar S, Singh AK, Banerjee P, Bhagavatula S.

Abstract:

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The molecular virology of Coronaviruses

Hartenian E, Nandakumar D, Lari A, Ly M, Tucker JM, Glaunsinger BA.

Abstract:

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Broad and differential animal ACE2 receptor usage by SARS-CoV-2

Zhao X, Chen D, Szabla R, Zheng M, Li G, Du P, Zheng S, Li X, Song C, Li R, Guo JT, Junop M, Zeng H, Lin H.

Abstract:

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Forensic DNA testing during the SARS-CoV-2 pandemic

De Ungria MCA.

Abstract:

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The Challenge of Virtual Voice Therapy During the COVID-19 Pandemic

Cantarella G, Barillari MR, Lechien JR, Pignataro L.

Abstract:

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Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

Ni W, Yang X, Yang D, Bao J, Li R, Xiao Y, Hou C, Wang H, Liu J, Yang D, Xu Y, Cao Z, Gao Z.

Abstract:

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NPC1 as a Modulator of Disease Severity and Viral Entry of Sars-CoV-2

Vial C, Calderón JF, Klein AD.

Abstract:

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RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery

Zhu W, Chen CZ, Gorshkov K, Xu M, Lo DC, Zheng W.

Abstract:

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COVID-19, Renin-Angiotensin System and Endothelial Dysfunction

Amraei R, Rahimi N.

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A perspective on potential antibody-dependent enhancement of SARS-CoV-2

Arvin AM, Fink K, Schmid MA, Cathcart A, Spreafico R, Havenar-Daughton C, Lanzavecchia A, Corti D, Virgin HW.

Abstract:

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Evaluation of the Aptima™ transcription-mediated amplification assay (Hologic®) for detecting SARS-CoV-2 in clinical specimens

Trémeaux P, Lhomme S, Abravanel F, Raymond S, Mengelle C, Mansuy JM, Izopet J.

Abstract:

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First results of a national external quality assessment scheme for the detection of SARS-CoV-2 genome sequences

Görzer I, Buchta C, Chiba P, Benka B, Camp JV, Holzmann H, Puchhammer-Stöckl E, Aberle SW.

Abstract:

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Cytologic and molecular correlates of SARS-CoV-2 infection of the nasopharynx

Nuovo GJ, Magro C, Mikhail A.

Abstract:

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Long-term infection of SARS-CoV-2 changed the body's immune status

Lin L, Luo S, Qin R, Yang M, Wang X, Yang Q, Zhang Y, Wang Q, Zhu R, Fan H, Wang H, Hu Y, Wang L, Hu D.

Abstract:

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Genome-wide analysis of Indian SARS-CoV-2 genomes for the identification of genetic mutation and SNP

Saha I, Ghosh N, Maity D, Sharma N, Sarkar JP, Mitra K.

Abstract:

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Immunoglobulin fragment F(ab')(2) against RBD potently neutralizes SARS-CoV-2 in vitro

Pan X, Zhou P, Fan T, Wu Y, Zhang J, Shi X, Shang W, Fang L, Jiang X, Shi J, Sun Y, Zhao S, Gong R, Chen Z, Xiao G.

Abstract:

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Intermittent fasting, a possible priming tool for host defense against SARS-CoV-2 infection: crosstalk among calorie restriction, autophagy and immune response

Hannan MA, Rahman MA, Rahman MS, Al Mamun Sohag A, Dash R, Hossain KS, Farjana M, Uddin MJ.

Abstract:

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[Are there genetic variants that can modify the course of the COVID-19 pandemic?]

Azurmendi PJ.

Abstract:

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Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans

Robson B.

Abstract:

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Michael Acceptors Tuned by the Pivotal Aromaticity of Histidine to Block COVID19 Activity

Poater A.

Abstract:

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The renin-angiotensin-aldosterone system: Role in pathogenesis and potential therapeutic target in COVID-19

Braga CL, Silva-Aguiar RP, Battaglini D, Peruchetti DB, Robba C, Pelosi P, Rocco PRM, Caruso-Neves C, Silva PL.

Abstract:

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The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity

Ovsyannikova IG, Haralambieva IH, Crooke SN, Poland GA, Kennedy RB.

Abstract:

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Severe acute respiratory syndrome coronavirus 2, original antigenic sin, and antibody-dependent enhancement: ménage à trois

Kadkhoda K.

Abstract:

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Proteomics and informatics for understanding phases and identifying biomarkers in COVID-19 disease

Whetton AD, Preston GW, Abubeker S, Geifman N.

Abstract:

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Types of Assays for SARS-CoV-2 Testing: A Review

Smithgall MC, Dowlatshahi M, Spitalnik SL, Hod EA, Rai AJ.

Abstract:

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SARS-CoV-2 will constantly sweep its tracks: a vaccine containing CpG motifs in 'lasso' for the multi-faced virus

Oberemok VV, Laikova KV, Yurchenko KA, Marochkin NA, Fomochkina II, Kubyshkin AV.

Abstract:

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Impact of Thiol-Disulfide Balance on the Binding of Covid-19 Spike Protein with Angiotensin-Converting Enzyme 2 Receptor

Hati S, Bhattacharyya S.

Abstract:

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Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARS-CoV-2 spike glycoprotein and its cellular receptor

Maurya VK, Kumar S, Prasad AK, Bhatt MLB, Saxena SK.

Abstract:

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Nanobodies: Prospects of Expanding the Gamut of Neutralizing Antibodies Against the Novel Coronavirus, SARS-CoV-2

Konwarh R.

Abstract:

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Targeting the NLRP3 Inflammasome in Severe COVID-19

Freeman TL, Swartz TH.

Abstract:

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Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies

Market M, Angka L, Martel AB, Bastin D, Olanubi O, Tennakoon G, Boucher DM, Ng J, Ardolino M, Auer RC.

Abstract:

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Biocides and Novel Antimicrobial Agents for the Mitigation of Coronaviruses

Dev Kumar G, Mishra A, Dunn L, Townsend A, Oguadinma IC, Bright KR, Gerba CP.

Abstract:

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Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein

Ye Q, West AMV, Silletti S, Corbett KD.

Abstract:

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SARS-CoV and SARS-CoV-2 main protease residue interaction networks change when bound to inhibitor N3

Griffin JWD.

Abstract:

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Computational insights into tetracyclines as inhibitors against SARS-CoV-2 M(pro) via combinatorial molecular simulation calculations

Bharadwaj S, Lee KE, Dwivedi VD, Kang SG.

Abstract:

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Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges

Hajivalili M, Hosseini M, Haji-Fatahaliha M.

Abstract:

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Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions

Kim SY, Jin W, Sood A, Montgomery DW, Grant OC, Fuster MM, Fu L, Dordick JS, Woods RJ, Zhang F, Linhardt RJ.

Abstract:

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In Silico Investigation of the SARS CoV2 Protease with Thymoquinone Major Constituent of Nigella Sativa

Kadil Y, Mouhcine M, Filali H.

Abstract:

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Comparative in silico design and validation of GPS‚Ñ¢ CoVID-19 dtec-RT-qPCR Test

Martínez-Murcia A, Bru G, Navarro A, Ros-Tárraga P, García-Sirera A, Pérez L.

Abstract:

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Coronavirus disease 2019 (COVID 19) and Malaria: Have anti glycoprotein antibodies a role?

Parodi A, Cozzani E.

Abstract:

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Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr.

Abstract:

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Caution in Identifying Coronaviruses by Electron Microscopy

Goldsmith CS, Miller SE.

Abstract:

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A Case for Targeting Th17 Cells and IL-17A in SARS-CoV-2 Infections

Orlov M, Wander PL, Morrell ED, Mikacenic C, Wurfel MM.

Abstract:

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Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates

Ren W, Sun H, Gao GF, Chen J, Sun S, Zhao R, Gao G, Hu Y, Zhao G, Chen Y, Jin X, Fang F, Chen J, Wang Q, Gong S, Gao W, Sun Y, Su J, He A, Cheng X, Li M, Xia C, Li M, Sun L.

Abstract:

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Energetics and IC50 based epitope screening in SARS CoV-2 (COVID 19) spike protein by immunoinformatic analysis implicating for a suitable vaccine development

Banerjee A, Santra D, Maiti S.

Abstract:

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Natural transmission of bat-like SARS-CoV-2ÔÅÑPRRA variants in COVID-19 patients

Wong YC, Lau SY, Wang To KK, Mok BWY, Li X, Wang P, Deng S, Woo KF, Du Z, Li C, Zhou J, Woo Chan JF, Yuen KY, Chen H, Chen Z.

Abstract:

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Potential Immunotherapeutic Targets For Hypoxia Due to COVI-FLU

Leyfman Y, Erick TK, Reddy SS, Galwankar S, Nanayakkara PWB, Di Somma S, Sharma P, Stawicki SP, Chaudry IH.

Abstract:

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Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review

Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC.

Abstract:

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Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection

Keam S, Megawati D, Patel SK, Tiwari R, Dhama K, Harapan H.

Abstract:

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COVID-19: Phylogenetic approaches may help in finding resources for natural cure

Zaman W, Saqib S, Ullah F, Ayaz A, Ye J.

Abstract:

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Deploying Biomolecules as Anti-COVID-19 Agents

Patel SKS, Lee JK, Kalia VC.

Abstract:

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Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling

Rockett RJ, Arnott A, Lam C, Sadsad R, Timms V, Gray KA, Eden JS, Chang S, Gall M, Draper J, Sim EM, Bachmann NL, Carter I, Basile K, Byun R, O'Sullivan MV, Chen SC, Maddocks S, Sorrell TC, Dwyer DE, Holmes EC, Kok J, Prokopenko M, Sintchenko V.

Abstract:

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Detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissue sections using commercially available reagents

Best Rocha A, Stroberg E, Barton LM, Duval EJ, Mukhopadhyay S, Yarid N, Caza T, Wilson JD, Kenan DJ, Kuperman M, Sharma SG, Larsen CP.

Abstract:

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Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

McKay PF, Hu K, Blakney AK, Samnuan K, Brown JC, Penn R, Zhou J, Bouton CR, Rogers P, Polra K, Lin PJC, Barbosa C, Tam YK, Barclay WS, Shattock RJ.

Abstract:

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Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Early Manifestations of COVID-19 in Israel

Cohen-Gihon I, Israeli O, Shifman O, Stein D, Achdout H, Weiss S, Mandelboim M, Erster O, Regev-Yochay G, Segal G, Yitzhaki S, Shapira SC, Beth-Din A, Zvi A.

Abstract:

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Coding-Complete Genome Sequence of SARS-CoV-2 Isolate from Bangladesh by Sanger Sequencing

Moniruzzaman M, Hossain MU, Islam MN, Rahman MH, Ahmed I, Rahman TA, Bhattacharjee A, Amin MR, Rashed A, Keya CA, Das KC, Salimullah M.

Abstract:

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Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response

Vishnubalaji R, Shaath H, Alajez NM.

Abstract:

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Comparative genomic signature representations of the emerging COVID-19 coronavirus and other coronaviruses: High identity and possible recombination between Bat and Pangolin coronaviruses

Touati R, Haddad-Boubaker S, Ferchichi I, Messaoudi I, Ouesleti AE, Triki H, Lachiri Z, Kharrat M.

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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies

Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR, Koranda N, Gristick HB, Gaebler C, Muecksch F, Lorenzi JCC, Finkin S, Hägglöf T, Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey M, Robbiani DF, Nussenzweig MC, Bjorkman PJ.

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The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu

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Erythropoietin Induced Hemoglobin Sub-Unit Beta may Stimulate Innate Immune RNA Virus Pattern Recognition, Suppress Reactive Oxygen Species, Reduce ACE2 Viral Doorway Opening and Neutrophil Extracellular Traps against Covid-19

Brenner SR.

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Tackling COVID-19 infection through complement-targeted immunotherapy

Jodele S, Köhl J.

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On the potential role of exosomes in the COVID-19 reinfection/reactivation opportunity

Elrashdy F, Aljaddawi AA, Redwan EM, Uversky VN.

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Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor

Tripathi MK, Singh P, Sharma S, Singh TP, Ethayathulla AS, Kaur P.

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Potential of NO donor furoxan as SARS-CoV-2