Vírus, Imunologia e Patogénese


A Multifunctional Peptide From Bacillus Fermented Soybean for Effective Inhibition of SARS-CoV-2 S1 Receptor Binding Domain and Modulation of Toll Like Receptor 4: A Molecular Docking Study

Padhi S, Sanjukta S, Chourasia R, Labala RK, Singh SP, Rai AK.

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Performance of the rapid high-throughput automated electrochemiluminescence immunoassay targeting total antibodies to the SARS-CoV-2 spike protein receptor binding domain in comparison to the neutralization assay

Resman Rus K, Korva M, Knap N, Avšič Županc T, Poljak M.

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Spike is the most recognized antigen in the whole-blood platform in both acute and convalescent COVID-19 patients

Aiello A, Fard SN, Petruccioli E, Petrone L, Vanini V, Farroni C, Cuzzi G, Navarra A, Gualano G, Mosti S, Pierelli L, Nicastri E, Goletti D.

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The SARS-CoV-2 Spike variant D614G favors an open conformational state

Mansbach RA, Chakraborty S, Nguyen K, Montefiori DC, Korber B, Gnanakaran S.

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Novel inhibitors of the main protease enzyme of SARS-CoV-2 identified via molecular dynamics simulation-guided in vitro assay

Loschwitz J, Jäckering A, Keutmann M, Olagunju M, Eberle RJ, Coronado MA, Olubiyi OO, Strodel B.

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Modifying a diagnostic SARS-CoV-2 Spike PCR to turn a Del69/70 drop-out into a discriminatory on-target assay

Nörz D, Pfefferle S, Grunwald M, Fischer N, Aepfelbacher M, Lütgehetmann M.

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Induction of Exaggerated Cytokine Production in Human Peripheral Blood Mononuclear Cells by a Recombinant SARS-CoV-2 Spike Glycoprotein S1 and Its Inhibition by Dexamethasone

Olajide OA, Iwuanyanwu VU, Lepiarz-Raba I, Al-Hindawi AA.

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Molecular optimization, docking, and dynamic simulation profiling of selective aromatic phytochemical ligands in blocking the SARS-CoV-2 S protein attachment to ACE2 receptor: an in silico approach of targeted drug designing

Dey D, Paul PK, Al Azad S, Al Mazid MF, Khan AM, Sharif MA, Rahman MH.

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Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities

Wehbe Z, Wehbe M, Iratni R, Pintus G, Zaraket H, Yassine HM, Eid AH.

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Publisher Correction: A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

Huang Q, Ji K, Tian S, Wang F, Huang B, Tong Z, Tan S, Hao J, Wang Q, Tan W, Gao GF, Yan J.

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Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discovery

Li Y, Hou G, Zhou H, Wang Y, Tun HM, Zhu A, Zhao J, Xiao F, Lin S, Liu D, Zhou D, Mai L, Zhang L, Zhang Z, Kuang L, Guan J, Chen Q, Wen L, Zhang Y, Zhuo J, Li F, Zhuang Z, Chen Z, Luo L, Liu D, Chen C, Gan M, Zhong N, Zhao J, Ren Y, Xu Y.

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Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model

Maeda DLNF, Tian D, Yu H, Dar N, Rajasekaran V, Meng S, Mahsoub HM, Sooryanarain H, Wang B, Heffron CL, Hassebroek A, LeRoith T, Meng XJ, Zeichner SL.

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Genome Sequences of Three SARS-CoV-2 ORF7a Deletion Variants Obtained from Patients in Hong Kong

Tse H, Wong SC, Ip KF, Cheng VC, To KK, Lung DC, Choi GK.

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Genome Sequences of Five SARS-CoV-2 Variants from Mumbai, India, Obtained by Nanopore Sequencing

Nilgiriwala K, Mandal A, Patel G, Mestry T, Vaswani S, Shaikh A, Sriraman K, Parikh S, Udupa S, Chatterjee N, Shastri J, Mistry N.

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Corrigendum to 'Simpler and faster Covid-19 testing: Strategies to streamline SARS-CoV-2 molecular assays'

Panpradist N, Wang Q, Ruth PS, Kotnik JH, Oreskovic AK, Miller A, Stewart SWA, Vrana J, Han PD, Beck IA, Starita LM, Frenkel LM, Lutz BR.

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Rapid screening for SARS-CoV-2 variants of concern in clinical and environmental samples using nested RT-PCR assays targeting key mutations of the spike protein

La Rosa G, Mancini P, Bonanno Ferraro G, Veneri C, Iaconelli M, Lucentini L, Bonadonna L, Brusaferro S, Brandtner D, Fasanella A, Pace L, Parisi A, Galante D, Suffredini E.

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Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study

Frampton D, Rampling T, Cross A, Bailey H, Heaney J, Byott M, Scott R, Sconza R, Price J, Margaritis M, Bergstrom M, Spyer MJ, Miralhes PB, Grant P, Kirk S, Valerio C, Mangera Z, Prabhahar T, Moreno-Cuesta J, Arulkumaran N, Singer M, Shin GY, Sanchez E, Paraskevopoulou SM, Pillay D, McKendry RA, Mirfenderesky M, Houlihan CF, Nastouli E.

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A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy

Kantsadi AL, Cattermole E, Matsoukas MT, Spyroulias GA, Vakonakis I.

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Identification of potential plant-based inhibitor against viral proteases of SARS-CoV-2 through molecular docking, MM-PBSA binding energy calculations and molecular dynamics simulation

Gogoi B, Chowdhury P, Goswami N, Gogoi N, Naiya T, Chetia P, Mahanta S, Chetia D, Tanti B, Borah P, Handique PJ.

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Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis

Bruter AV, Korshunova DS, Kubekina MV, Sergiev PV, Kalinina AA, Ilchuk LA, Silaeva YY, Korshunov EN, Soldatov VO, Deykin AV.

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Comparison Between a Standard and SalivaDirect RNA Extraction Protocol for Molecular Diagnosis of SARS-CoV-2 Using Nasopharyngeal Swab and Saliva Clinical Samples

Rodríguez Flores SN, Rodríguez-Martínez LM, Reyes-Berrones BL, Fernández-Santos NA, Sierra-Moncada EJ, Rodríguez-Pérez MA.

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Identification of B.1.346 Lineage of SARS-CoV-2 in Japan: Genomic Evidence of Re-entry of Clade 20C

Abe K, Shimura T, Takenouchi T, Iwasaki YW, Ishizu H, Uwamino Y, Uno S, Gotoh J, Tachikawa N, Takeuchi Y, Katayama J, Nozaki H, Fujii S, Seki S, Nakamura M, Uda K, Misumi T, Ishihara J, Yamada K, Kanai T, Murai S, Araki K, Ebihara T, Siomi H, Hasegawa N, Kitagawa Y, Amagai M, Suematsu M, Kosaki K.

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An efficient system to generate truncated human angiotensin converting enzyme 2 (hACE2) capable of binding RBD and spike protein of SARS-CoV2

Gao X, Liang K, Mei S, Peng S, Vong EG, Zhan J.

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Rapid Acquisition of High-Quality SARS-CoV-2 Genome via Amplicon-Oxford Nanopore Sequencing

Yan Y, Wu K, Chen J, Liu H, Huang Y, Zhang Y, Xiong J, Quan W, Wu X, Liang Y, He K, Jia Z, Wang D, Liu D, Wei H, Chen J.

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mRNA vaccination compared to infection elicits an IgG-predominant response with greater SARS-CoV-2 specificity and similar decrease in variant spike recognition

Röltgen K, Nielsen SCA, Arunachalam PS, Yang F, Hoh RA, Wirz OF, Lee AS, Gao F, Mallajosyula V, Li C, Haraguchi E, Shoura MJ, Wilbur JL, Wohlstadter JN, Davis MM, Pinsky BA, Sigal GB, Pulendran B, Nadeau KC, Boyd SD.

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Genomic epidemiology of SARS-CoV-2 transmission lineages in Ecuador

Gutierrez B, Márquez S, Prado-Vivar B, Becerra-Wong M, Guadalupe JJ, da Silva Candido D, Fernandez-Cadena JC, Morey-Leon G, Armas-Gonzalez R, Andrade-Molina DM, Bruno A, de Mora D, Olmedo M, Portugal D, Gonzalez M, Orlando A, Drexler JF, Moreira-Soto A, Sander AL, Brünink S, Kühne A, Patiño L, Carrazco-Montalvo A, Mestanza O, Zurita J, Sevillano G, du Plessis L, McCrone JT, Coloma J, Trueba G, Barragán V, Rojas-Silva P, Grunauer M, Kraemer MUG, Faria NR, Escalera-Zamudio M, Pybus OG, Cárde

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Drug repositioning candidates identified using in-silico quasi-quantum molecular simulation demonstrate reduced COVID-19 mortality in 1.5M patient records

Alamgir J, Yajima M, Ergas R, Chen X, Hill N, Munir N, Saeed M, Gersing K, Haendel M, Chute CG, Abid MR.

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An Autoantigen-ome from HS-Sultan B-Lymphoblasts Offers a Molecular Map for Investigating Autoimmune Sequelae of COVID-19

Wang JY, Zhang W, Roehrl VB, Roehrl MW, Roehrl MH.

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Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity

Volpatti LR, Wallace RP, Cao S, Raczy MM, Wang R, Gray LT, Alpar AT, Briquez PS, Mitrousis N, Marchell TM, Sasso MS, Nguyen M, Mansurov A, Budina E, Solanki A, Watkins EA, Schnorenberg MR, Tremain AC, Reda JW, Nicolaescu V, Furlong K, Dvorkin S, Yu SS, Manicassamy B, LaBelle JL, Tirrell MV, Randall G, Kwissa M, Swartz MA, Hubbell JA.

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A repurposed drug screen identifies compounds that inhibit the binding of the COVID-19 spike protein to ACE2

Tsegay KB, Adeyemi CM, Gniffke EP, Sather DN, Walker JK, Smith SEP.

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Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300

Davis DA, Bulut H, Shrestha P, Yaparla A, Jaeger HK, Hattori SI, Wingfield P, Mitsuya H, Yarchoan R.

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Deletion of ER-retention Motif on SARS-CoV-2 Spike Protein Reduces Cell Hybrid During Cell-cell Fusion

Chen CH, Badeti S, Cho JH, Naghizadeh A, Wang X, Liu D.

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Virus-receptor interactions of SARS-CoV-2 spike receptor-binding domain and human neuropilin-1 b1 domain

Alnomasy SF.

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Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns

Ernandes MJ, Kagan JC.

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Leveraging Genomic Associations in Precision Digital Care for Weight Loss: Cohort Study

Sinha R, Kachru D, Ricchetti RR, Singh-Rambiritch S, Muthukumar KM, Singaravel V, Irudayanathan C, Reddy-Sinha C, Junaid I, Sharma G, Airey C, Francis-Lyon PA.

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Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (M(pro)) with pharmacokinetics and toxicological properties

Panikar S, Shoba G, Arun M, Sahayarayan JJ, Usha Raja Nanthini A, Chinnathambi A, Alharbi SA, Nasif O, Kim HJ.

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SARS-CoV-2 spike E484K mutation reduces antibody neutralisation

Jangra S, Ye C, Rathnasinghe R, Stadlbauer D; Personalized Virology Initiative study group, Krammer F, Simon V, Martinez-Sobrido L, García-Sastre A, Schotsaert M.

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Construction, petro-collecting/dispersing capacities, antimicrobial activity, and molecular docking study of new cationic surfactant-sulfonamide conjugates

Tantawy AH, Shaban MM, Jiang H, Wang MQ, Mohamed HI.

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Synthesis, antimicrobial activity, density functional modelling and molecular docking with COVID-19 main protease studies of benzoxazole derivative: 2-(p-chloro-benzyl)-5-[3-(4-ethly-1-piperazynl) propionamido]-benzoxazole

Zeyrek CT, Arpacı ÖT, Arısoy M, Onurdağ FK.

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Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2

Suryamohan K, Diwanji D, Stawiski EW, Gupta R, Miersch S, Liu J, Chen C, Jiang YP, Fellouse FA, Sathirapongsasuti JF, Albers PK, Deepak T, Saberianfar R, Ratan A, Washburn G, Mis M, Santhosh D, Somasekar S, Hiranjith GH, Vargas D, Mohan S, Phalke S, Kuriakose B, Antony A, Ustav M Jr, Schuster SC, Sidhu S, Junutula JR, Jura N, Seshagiri S.

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The Use of In Silico Tools for the Toxicity Prediction of Potential Inhibitors of SARS-CoV-2

Bhat V, Chatterjee J.

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Use of low-molecular weight heparin, transfusion and mortality in COVID-19 patients not requiring ventilation

Grandone E, Tiscia G, Pesavento R, De Laurenzo A, Ceccato D, Sartori MT, Mirabella L, Cinnella G, Mastroianno M, Dalfino L, Colaizzo D, Vettor R, Intrieri M, Ostuni A, Margaglione M; CSS- COVID.

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Structure-based identification of SARS-CoV-2 main protease inhibitors from anti-viral specific chemical libraries: an exhaustive computational screening approach

Bhowmick S, Saha A, Osman SM, Alasmary FA, Almutairi TM, Islam MA.

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SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

Mandolesi M, Sheward DJ, Hanke L, Ma J, Pushparaj P, Perez Vidakovics L, Kim C, Àdori M, Lenart K, Loré K, Castro Dopico X, Coquet JM, McInerney GM, Karlsson Hedestam GB, Murrell B.

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Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data

Khare S, Azevedo M, Parajuli P, Gokulan K.

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Computational molecular docking and virtual screening revealed promising SARS-CoV-2 drugs

Hosseini M, Chen W, Xiao D, Wang C.

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Potential combination therapy using twenty phytochemicals from twenty plants to prevent SARS- CoV-2 infection: An in silico Approach

Dey D, Dey N, Ghosh S, Chandrasekaran N, Mukherjee A, Thomas J.

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In silico approach to understand the epigenetic mechanism of SARS-CoV-2 and its impact on the environment

Qazi S, Sheikh K, Raza K.

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Phytochemicals as potential drug candidates for targeting SARS CoV 2 proteins, an in silico study

Nag A, Banerjee R, Chowdhury RR, Krishnapura Venkatesh C.

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First Movers in Molecular Detection: Case Comparison on Harnessing Research and Development, Industry, and Entrepreneurship

Yeh KB, Scullion M, Michelotti JM, Olinger G.

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Computational screening of FDA approved drugs of fungal origin that may interfere with SARS-CoV-2 spike protein activation, viral RNA replication, and post-translational modification: a multiple target approach

Singh R, Gautam A, Chandel S, Sharma V, Ghosh A, Dey D, Roy S, Ravichandiran V, Ghosh D.

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In search of drugs to alleviate suppression of the host's innate immune responses against SARS-CoV-2 using a molecular modeling approach

Choudhury S, Moulick D, Borah A, Saikia P, Mazumder MK.

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Binding ability of arginine, citrulline, N-acetyl citrulline and thiocitrulline with SARS COV-2 main protease using molecular docking studies

Thimmasandra Narayan R.

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A Case of Moderately Severe COVID-19 in a Healthcare Worker in Russia: Virus Isolation and Full Genome Sequencing

Shchetinin AM, Tsyganova EV, Protsenko DN, Botikov AG, Gushchin V.

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Alternate primers for whole-genome SARS-CoV-2 sequencing

Cotten M, Lule Bugembe D, Kaleebu P, V T Phan M.

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Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

Watterson D, Wijesundara DK, Modhiran N, Mordant FL, Li Z, Avumegah MS, McMillan CL, Lackenby J, Guilfoyle K, van Amerongen G, Stittelaar K, Cheung ST, Bibby S, Daleris M, Hoger K, Gillard M, Radunz E, Jones ML, Hughes K, Hughes B, Goh J, Edwards D, Scoble J, Pearce L, Kowalczyk L, Phan T, La M, Lu L, Pham T, Zhou Q, Brockman DA, Morgan SJ, Lau C, Tran MH, Tapley P, Villalón-Letelier F, Barnes J, Young A, Jaberolansar N, Scott CA, Isaacs A, Amarilla AA, Khromykh AA, van den Brand JM, Reading PC

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Temperature effect on the SARS-CoV-2: A molecular dynamics study of the spike homotrimeric glycoprotein

Martí D, Torras J, Bertran O, Turon P, Alemán C.

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Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Based Novel Epitopes Induce Potent Immune Responses in vivo and Inhibit Viral Replication in vitro

Vishwakarma P, Yadav N, Rizvi ZA, Khan NA, Chiranjivi AK, Mani S, Bansal M, Dwivedi P, Shrivastava T, Kumar R, Awasthi A, Ahmed S, Samal S.

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An in silico approach to target RNA-dependent RNA polymerase of COVID-19 with naturally occurring phytochemicals

Mahrosh HS, Mustafa G.

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Reviving chloroquine for anti-SARS-CoV-2 treatment with cucurbit[7]uril-based supramolecular formulation

Kwong CHT, Mu J, Li S, Fang Y, Liu Q, Zhang X, Kam H, Lee SMY, Chen Y, Deng F, Zhou X, Wang R.

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The identification of novel inhibitors of human angiotensin-converting enzyme 2 and main protease of Sars-Cov-2: A combination of in silico methods for treatment of COVID-19

Zarezade V, Rezaei H, Shakerinezhad G, Safavi A, Nazeri Z, Veisi A, Azadbakht O, Hatami M, Sabaghan M, Shajirat Z.

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Rational design of flavonoid based potential inhibitors targeting SARS-CoV 3CL protease for the treatment of COVID-19

Bhati S, Kaushik V, Singh J.

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ACoRE: Accurate SARS-CoV-2 genome reconstruction for the characterization of intra-host and inter-host viral diversity in clinical samples and for the evaluation of re-infections

Marcolungo L, Beltrami C, Esposti CD, Lopatriello G, Piubelli C, Mori A, Pomari E, Deiana M, Scarso S, Bisoffi Z, Grosso V, Cosentino E, Maestri S, Lavezzari D, Iadarola B, Paterno M, Segala E, Giovannone B, Gallinaro M, Rossato M, Delledonne M.

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Corrigendum to "Naringerin as candidate drug against SARS-CoV-2: The role for TPC2 genomic variants in COVID-19" [Pharmacol. Res. 164 (2021) 105402]

Di Maria E, Martini P, Gennarelli M.

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Free SARS-CoV-2 Spike Protein S1 Particles May Play a Role in the Pathogenesis of COVID-19 Infection

Letarov AV, Babenko VV, Kulikov EE.

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Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2

Attia GH, Moemen YS, Youns M, Ibrahim AM, Abdou R, El Raey MA.

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Robust antimicrobial photodynamic therapy with Curcumin-Poly (Lactic-co-Glycolic Acid) nanoparticles against COVID-19: A preliminary in vitro study in Vero cell line as a model

Pourhajibagher M, Azimi M, Haddadi-Asl V, Ahmadi H, Gholamzad M, Ghorbanpour S, Bahador A.

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Is SARS-CoV-2 Spike glycoprotein impairing macrophage function via α7-nicotinic acetylcholine receptors?

Tanmay S, Labrou D, Farsalinos K, Poulas K.

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Investigation of angucycline compounds as potential drug candidates against SARS Cov-2 main protease using docking and molecular dynamic approaches

Al-Bustany HA, Ercan S, Ince E, Pirinccioglu N.

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GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein

Zhao M, Yu Y, Sun LM, Xing JQ, Li T, Zhu Y, Wang M, Yu Y, Xue W, Xia T, Cai H, Han QY, Yin X, Li WH, Li AL, Cui J, Yuan Z, Zhang R, Zhou T, Zhang XM, Li T.

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Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19

Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, Aepfelbacher M, Nörz D, Lütgehetmann M, Pfefferle S, Schultheiss M.

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Identification of COVID-19 subtypes based on immunogenomic profiling

Chen Z, Feng Q, Zhang T, Wang X.

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Focused Role of Nanoparticles Against COVID-19: Diagnosis and Treatment

Dheyab MA, Khaniabadi PM, Aziz AA, Jameel MS, Mehrdel B, Oglat AA, Khaleel HA.

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Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant

Graham C, Seow J, Huettner I, Khan H, Kouphou N, Acors S, Winstone H, Pickering S, Galao RP, Dupont L, Lista MJ, Jimenez-Guardeño JM, Laing AG, Wu Y, Joseph M, Muir L, van Gils MJ, Ng WM, Duyvesteyn HME, Zhao Y, Bowden TA, Shankar-Hari M, Rosa A, Cherepanov P, McCoy LE, Hayday AC, Neil SJD, Malim MH, Doores KJ.

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Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS-CoV-2 infection

Nanda P, Ghosh A.

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Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates

Yao YF, Wang ZJ, Jiang RD, Hu X, Zhang HJ, Zhou YW, Gao G, Chen Y, Peng Y, Liu MQ, Zhang YN, Min J, Lu J, Gao XX, Guo J, Peng C, Shen XR, Li Q, Zhao K, Yang L, Wan X, Zhang B, Wang WH, Wu J, Zhou P, Yang XL, Shen S, Shan C, Yuan ZM, Shi ZL.

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Genome Analysis for Sequence Variants in SARS-CoV-2 Among Asymptomatic Individuals in a Long-term Care Facility

Abdalhamid B, Iwen PC, Wiley MR, Pratt CB, Hinrichs SH.

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Investigation into molecular mechanisms and high-frequency core TCM for pulmonary fibrosis secondary to COVID-19 based on network pharmacology and data mining

Yu MX, Song X, Ma XQ, Hao CX, Huang JJ, Yang WH.

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In silico analysis of the potential mechanism of a preventive Chinese medicine formula on coronavirus disease 2019

Wu H, Gong K, Qin Y, Yuan Z, Xia S, Zhang S, Yang J, Yang P, Li L, Xie M.

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Antiviral potential of plant polysaccharide nanoparticles actuating non-specific immunity

Stovbun SV, Kalinina TS, Zlenko DV, Kiselev AV, Litvin AA, Bukhvostov AA, Usachev SV, Kuznetsov DA.

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High-throughput, single-copy sequencing reveals SARS-CoV-2 spike variants coincident with mounting humoral immunity during acute COVID-19

Ko SH, Bayat Mokhtari E, Mudvari P, Stein S, Stringham CD, Wagner D, Ramelli S, Ramos-Benitez MJ, Strich JR, Davey RT Jr, Zhou T, Misasi J, Kwong PD, Chertow DS, Sullivan NJ, Boritz EA.

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Evaluation of rapid SARS-CoV-2 antigen tests, AFIAS COVID-19 Ag and ichroma COVID-19 Ag, with serial nasopharyngeal specimens from COVID-19 patients

Kweon OJ, Lim YK, Kim HR, Choi Y, Kim MC, Choi SH, Chung JW, Lee MK.

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Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights

Aguilar-Ordoñez I, Pérez-Villatoro F, García-Ortiz H, Barajas-Olmos F, Ballesteros-Villascán J, González-Buenfil R, Fresno C, Garcíarrubio A, Fernández-López JC, Tovar H, Hernández-Lemus E, Orozco L, Soberón X, Morett E.

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IgG and IgM antibody formation to spike and nucleocapsid proteins in COVID-19 characterized by multiplex immunoblot assays

Shah J, Liu S, Potula HH, Bhargava P, Cruz I, Force D, Bazerbashi A, Ramasamy R.

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Identification of doxorubicin as a potential therapeutic against SARS-CoV-2 (COVID-19) protease: a molecular docking and dynamics simulation studies

Sajid Jamal QM, Alharbi AH, Ahmad V.

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Vitamin D is a potential inhibitor of COVID-19: In silico molecular docking to the binding site of SARS-CoV-2 endoribonuclease Nsp15

Shalayel MH, Al-Mazaideh GM, Aladaileh SH, Al-Swailmi FK, Al-Thiabat MG.

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Electrochemical Resonance of Molecular Motion Enabling Label-, Antibody-, and Enzyme-Free Detection of SARS-CoV-2

Zhou L, Hao P, Li H, Zhang Z.

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Longitudinal Assessment of SARS-CoV-2 Anti-Nucleocapsid and anti-Spike-1-RBD Antibody Testing Following PCR-Detected SARS-CoV-2 Infection

El-Khoury JM, Schulz WL, Durant TJS.

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Choice of assemblers has a critical impact on de novo assembly of SARS-CoV-2 genome and characterizing variants

Islam R, Raju RS, Tasnim N, Shihab IH, Bhuiyan MA, Araf Y, Islam T.

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In Silico investigation of the viroporin E as a vaccine target against SARS-CoV-2

Rouka E, Gourgoulianis KI, Zarogiannis SG.

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Chaga Medicinal Mushroom Inonotus obliquus (Agaricomycetes) Terpenoids May Interfere with SARS-CoV-2 Spike Protein Recognition of the Host Cell: A Molecular Docking Study

Basal WT, Elfiky A, Eid J.

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Silibinin as potential tool against SARS-Cov-2: In silico spike receptor-binding domain and main protease molecular docking analysis, and in vitro endothelial protective effects

Speciale A, Muscarà C, Molonia MS, Cimino F, Saija A, Giofrè SV.

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Pan-selectin inhibitors as potential therapeutics for COVID-19 treatment: in silico screening study

Šmak P, Chandrabose S, Tvaroška I, Koča J.

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Efficient maternofetal transplacental transfer of anti- SARS-CoV-2 spike antibodies after antenatal SARS-CoV-2 BNT162b2 mRNA vaccination

Rottenstreich A, Zarbiv G, Oiknine-Djian E, Zigron R, Wolf DG, Porat S.

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Guillain-Barré syndrome, SARS-CoV-2 and molecular mimicry

Lucchese G, Flöel A.

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Reply: Guillain-Barré syndrome, SARS-CoV-2 and molecular mimicry and Ongoing challenges in unravelling the association between COVID-19 and Guillain-Barré syndrome and Unclear association between COVID-19 and Guillain-Barré syndrome and Currently available data regarding the potential associa

Lunn MP, Carr AC, Keddie S, Pakpoor J, Pipis M, Willison HJ.

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Genomic Insights into the Human Susceptibility to SARS-CoV-2 Infection

Magalhães AC, Pedro N, Pereira L.

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Qualitatively distinct modes of Sputnik V vaccine-neutralization escape by SARS-CoV-2 Spike variants

Ikegame S, Siddiquey MNA, Hung CT, Haas G, Brambilla L, Oguntuyo KY, Kowdle S, Vilardo AE, Edelstein A, Perandones C, Kamil JP, Lee B.

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Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein

Zhang S, Go EP, Ding H, Anang S, Kappes JC, Desaire H, Sodroski J.

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Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

Kastenhuber ER, Jaimes JA, Johnson JL, Mercadante M, Muecksch F, Weisblum Y, Bram Y, Schwartz RE, Whittaker GR, Cantley LC.

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An overview of basic molecular biology of SARS-CoV-2 and current COVID-19 prevention strategies

Das A, Ahmed R, Akhtar S, Begum K, Banu S.

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Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene

Hartley PD, Tillett RL, AuCoin DP, Sevinsky JR, Xu Y, Gorzalski A, Pandori M, Buttery E, Hansen H, Picker MA, Rossetto CC, Verma SC.

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Serum levels of SARS-CoV-2 nucleocapsid antigen associate with inflammatory status and disease severity in COVID-19 patients

Perna F, Bruzzaniti S, Piemonte E, Maddaloni V, Atripaldi L, Sale S, Sanduzzi A, Nicastro C, Pepe N, Bifulco M, Matarese G, Galgani M, Atripaldi L.

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Comparative analysis of various clinical specimens in detection of SARS-CoV-2 using rRT-PCR in new and follow up cases of COVID-19 infection: Quest for the best choice

Sharma K, Aggarwala P, Gandhi D, Mathias A, Singh P, Sharma S, Negi SS, Bhargava A, Das P, Gaikwad U, Wankhede A, Behra A, Nagarkar NM.

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The role of autophagy in controlling of SARS-CoV-2 infection: An overview with virophagy-mediated of molecular drug targets

Sargazi S, Sheervalilou R, Rokni M, Shirvaliloo M, Shahraki O, Rezaei N.

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Symptomatic reinfection of SARS-CoV-2 with spike protein variant N440K associated with immune escape

Rani PR, Imran M, Lakshmi JV, Jolly B, Jain A, Surekha A, Senthivel V, Chandrasekhar P, Divakar MK, Srinivasulu D, Bhoyar RC, Vanaja PR, Scaria V, Sivasubbu S.

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Feasibility, efficiency & effectiveness of pooled sample testing strategy (pooled NAAT) for molecular testing of COVID-19

Prakash S, Prakash O, Mishra H, Khan DN, Shukla S, Pandey A, Rade K, Gupta N, Bhatt MLB, Jain A.

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Prediction of potential small interfering RNA molecules for silencing of the spike gene of SARS-CoV-2

Panda K, Alagarasu K, Cherian SS, Parashar D.

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Phylogenetic classification of the whole-genome sequences of SARS-CoV-2 from India & evolutionary trends

Potdar V, Vipat V, Ramdasi A, Jadhav S, Pawar-Patil J, Walimbe A, Patil SS, Choudhury ML, Shastri J, Agrawal S, Pawar S, Lole K, Abraham P, Cherian S; ICMR-NIV NIC Team.

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Drug repurposing for identification of potential inhibitors against SARS-CoV-2 spike receptor-binding domain: An in silico approach

Behera SK, Mahapatra N, Tripathy CS, Pati S.

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Investigating the ACE2 polymorphisms in COVID-19 susceptibility: An in silico analysis

Pouladi N, Abdolahi S.

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Challenges of SARS-CoV-2 genomic surveillance in Africa

Adepoju P.

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New insights into application of nanoparticles in the diagnosis and screening of novel coronavirus (SARS-CoV-2)

Tharayil A, Rajakumari R, Kumar A, Choudhary MD, Palit P, Thomas S.

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Prediction of potential inhibitors of SARS-CoV-2 using 3D-QSAR, molecular docking modeling and ADMET properties

Khaldan A, Bouamrane S, En-Nahli F, El-Mernissi R, El Khatabi K, Hmamouchi R, Maghat H, Ajana MA, Sbai A, Bouachrine M, Lakhlifi T.

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The Socio-impact of COVID-19 positive patients in Bangladesh: A study on clinical data from a COVID-19 testing laboratory: SARS-CoV-2 molecular identification and clinical data analysis of associated risk factors from a COVID-19 testing laboratory of a coastal region in Bangladesh

Ali R, Chowdhury R, Mas-Ud A, Islam S, Shimu AS, Mina FB, Sharmin NE, Hasan F.

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Case Report: Administration of Amniotic Fluid-Derived Nanoparticles in Three Severely Ill COVID-19 Patients

Mitrani MI, Bellio MA, Sagel A, Saylor M, Kapp W, VanOsdol K, Haskell G, Stewart D, Abdullah Z, Santos I, Milberg J, Arango A, Mitrani A, Shapiro GC.

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A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing

Kumar SU, Priya NM, Nithya SR, Kannan P, Jain N, Kumar DT, Magesh R, Younes S, Zayed H, Doss CGP.

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Molecular detection of SARS-CoV-2 being challenged by virus variation and asymptomatic infection

Jiang C, Li X, Ge C, Ding Y, Zhang T, Cao S, Meng L, Lu S.

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Genomic Variations in SARS-CoV-2 Genomes From Gujarat: Underlying Role of Variants in Disease Epidemiology

Joshi M, Puvar A, Kumar D, Ansari A, Pandya M, Raval J, Patel Z, Trivedi P, Gandhi M, Pandya L, Patel K, Savaliya N, Bagatharia S, Kumar S, Joshi C.

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Genomic Feature Analysis of Betacoronavirus Provides Insights Into SARS and COVID-19 Pandemics

Li X, Chang J, Chen S, Wang L, Yau TO, Zhao Q, Hong Z, Ruan J, Duan G, Gao S.

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Unmasking of crucial structural fragments for coronavirus protease inhibitors and its implications in COVID-19 drug discovery

Ghosh K, Amin SA, Gayen S, Jha T.

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A SARS-CoV-2 -human metalloproteome interaction map

Chasapis CT, Georgiopoulou AK, Perlepes SP, Bjørklund G, Peana M.

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Targeted design of drug binding sites in the main protease of SARS-CoV-2 reveals potential signatures of adaptation

Padhi AK, Tripathi T.

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ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model

Vandyck K, Abdelnabi R, Gupta K, Jochmans D, Jekle A, Deval J, Misner D, Bardiot D, Foo CS, Liu C, Ren S, Beigelman L, Blatt LM, Boland S, Vangeel L, Dejonghe S, Chaltin P, Marchand A, Serebryany V, Stoycheva A, Chanda S, Symons JA, Raboisson P, Neyts J.

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Structure-based drug design of an inhibitor of the SARS-CoV-2 (COVID-19) main protease using free software: A tutorial for students and scientists

Zhang S, Krumberger M, Morris MA, Parrocha CMT, Kreutzer AG, Nowick JS.

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EFFECT OF RAMIPRIL ON KIDNEY, LUNG AND HEART ACE2 IN A DIABETIC MICE MODEL

Vergara A, Jacobs-Cachá C, Molina-Van den Bosch M, Domínguez-Báez P, Benito B, García-Carro C, Serón D, Soler MJ.

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In silico inquest reveals the efficacy of Cannabis in the treatment of post-Covid-19 related neurodegeneration

Sarkar I, Sen G, Bhattyachariya M, Bhattacharyya S, Sen A.

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Synthesis and Characterization of a Minophosphonate Containing Chitosan Polymer Derivatives: Investigations of Cytotoxic Activity and in Silico Study of SARS-CoV-19

Packialakshmi P, Gobinath P, Ali D, Alarifi S, Alsaiari NS, Idhayadhulla A, Surendrakumar R.

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Molecular Basis of the Therapeutical Potential of Clove (Syzygium aromaticum L.) and Clues to Its Anti-COVID-19 Utility

Vicidomini C, Roviello V, Roviello GN.

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Potent Neutralization Antibodies Induced by a Recombinant Trimeric Spike Protein Vaccine Candidate Containing PIKA Adjuvant for COVID-19

Tong J, Zhu C, Lai H, Feng C, Zhou D.

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Linear B-Cell Epitope Prediction for In Silico Vaccine Design: A Performance Review of Methods Available via Command-Line Interface

Galanis KA, Nastou KC, Papandreou NC, Petichakis GN, Pigis DG, Iconomidou VA.

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Interacting Proteins, Polymorphisms and the Susceptibility of Animals to SARS-CoV-2

Hancock JT, Rouse RC, Stone E, Greenhough A.

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LipoParticles: Lipid-Coated PLA Nanoparticles Enhanced In Vitro mRNA Transfection Compared to Liposomes

Ayad C, Libeau P, Lacroix-Gimon C, Ladavière C, Verrier B.

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Phylogenomic Evidence of Reinfection and Persistence of SARS-CoV-2: First Report from Colombia

Ramírez JD, Muñoz M, Ballesteros N, Patiño LH, Castañeda S, Rincón CA, Mendez C, Oliveros C, Perez J, Márquez EK, Ortiz FLS, Correa-Cárdenas CA, Duque MC, Paniz-Mondolfi A.

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Exaptation of Retroviral Syncytin for Development of Syncytialized Placenta, Its Limited Homology to the SARS-CoV-2 Spike Protein and Arguments against Disturbing Narrative in the Context of COVID-19 Vaccination

Kloc M, Uosef A, Kubiak JZ, Ghobrial RM.

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The Inhibitory Effects of Plant Derivate Polyphenols on the Main Protease of SARS Coronavirus 2 and Their Structure-Activity Relationship

Nguyen TTH, Jung JH, Kim MK, Lim S, Choi JM, Chung B, Kim DW, Kim D.

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SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome

Sardanelli AM, Isgrò C, Palese LL.

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CNBP Binds and Unfolds In Vitro G-Quadruplexes Formed in the SARS-CoV-2 Positive and Negative Genome Strands

Bezzi G, Piga EJ, Binolfi A, Armas P.

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Molecular Analysis of SARS-CoV-2 Genetic Lineages in Jordan: Tracking the Introduction and Spread of COVID-19 UK Variant of Concern at a Country Level

Sallam M, Mahafzah A.

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Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG

Eberhardt KA, Dewald F, Heger E, Gieselmann L, Vanshylla K, Wirtz M, Kleipass F, Johannis W, Schommers P, Gruell H, Brensing KA, Müller RU, Augustin M, Lehmann C, Koch M, Klein F, Di Cristanziano V.

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Repurposing of Some Natural Product Isolates as SARS-COV-2 Main Protease Inhibitors via In Vitro Cell Free and Cell-Based Antiviral Assessments and Molecular Modeling Approaches

Abdallah HM, El-Halawany AM, Sirwi A, El-Araby AM, Mohamed GA, Ibrahim SRM, Koshak AE, Asfour HZ, Awan ZA, A Elfaky M.

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Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells

Bagdonaite I, Thompson AJ, Wang X, Søgaard M, Fougeroux C, Frank M, Diedrich JK, Yates JR 3rd, Salanti A, Vakhrushev SY, Paulson JC, Wandall HH.

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SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021-Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing

Goncalves Cabecinhas AR, Roloff T, Stange M, Bertelli C, Huber M, Ramette A, Chen C, Nadeau S, Gerth Y, Yerly S, Opota O, Pillonel T, Schuster T, Metzger CMJA, Sieber J, Bel M, Wohlwend N, Baumann C, Koch MC, Bittel P, Leuzinger K, Brunner M, Suter-Riniker F, Berlinger L, Søgaard KK, Beckmann C, Noppen C, Redondo M, Steffen I, Seth-Smith HMB, Mari A, Lienhard R, Risch M, Nolte O, Eckerle I, Martinetti Lucchini G, Hodcroft EB, Neher RA, Stadler T, Hirsch HH, Leib SL, Risch L, Kaiser L, Trkola A,

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Placental Immune Responses to Viruses: Molecular and Histo-Pathologic Perspectives

Narang K, Cheek EH, Enninga EAL, Theiler RN.

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Immunogenicity and Neutralizing Activity Comparison of SARS-CoV-2 Spike Full-Length and Subunit Domain Proteins in Young Adult and Old-Aged Mice

Kim KH, Bhatnagar N, Jeeva S, Oh J, Park BR, Shin CH, Wang BZ, Kang SM.

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Genomic Intelligence as Über Bio-Cybersecurity: The Gödel Sentence in Immuno-Cognitive Systems

Markose SM.

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Soluble Spike DNA Vaccine Provides Long-Term Protective Immunity against SARS-CoV-2 in Mice and Nonhuman Primates

Seo YB, Suh YS, Ryu JI, Jang H, Oh H, Koo BS, Seo SH, Hong JJ, Song M, Kim SJ, Sung YC.

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Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study

Abdelaal Ahmed Mahmoud M Alkhatip A, Georgakis M, Montero Valenzuela LR, Hamza M, Farag E, Hodgkinson J, Hosny H, Kamal AM, Wagih M, Naguib A, Yassin H, Algameel H, Elayashy M, Abdelhaq M, Younis MI, Mohamed H, Abdulshafi M, Elramely MA.

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Metagenomic Snapshots of Viral Components in Guinean Bats

Hermida Lorenzo RJ, Cadar D, Koundouno FR, Juste J, Bialonski A, Baum H, García-Mudarra JL, Hakamaki H, Bencsik A, Nelson EV, Carroll MW, Magassouba N, Günther S, Schmidt-Chanasit J, Muñoz Fontela C, Escudero-Pérez B.

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SARS-CoV-2 Molecular Transmission Clusters and Containment Measures in Ten European Regions during the First Pandemic Wave

Bousali M, Dimadi A, Kostaki EG, Tsiodras S, Nikolopoulos GK, Sgouras DN, Magiorkinis G, Papatheodoridis G, Pogka V, Lourida G, Argyraki A, Angelakis E, Sourvinos G, Beloukas A, Paraskevis D, Karamitros T.

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Detection and Genome Sequencing of SARS-CoV-2 in a Domestic Cat with Respiratory Signs in Switzerland

Klaus J, Meli ML, Willi B, Nadeau S, Beisel C, Stadler T, Eth Sars-CoV-Sequencing Team, Egberink H, Zhao S, Lutz H, Riond B, Rösinger N, Stalder H, Renzullo S, Hofmann-Lehmann R.

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Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary

Shirazi S, Stanford CM, Cooper LF.

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Determination of the Concentration of IgG against the Spike Receptor-Binding Domain That Predicts the Viral Neutralizing Activity of Convalescent Plasma and Serum against SARS-CoV-2

Santiago L, Uranga-Murillo I, Arias M, González-Ramírez AM, Macías-León J, Moreo E, Redrado S, García-García A, Taleb V, Lira-Navarrete E, Hurtado-Guerrero R, Aguilo N, Del Mar Encabo-Berzosa M, Hidalgo S, Galvez EM, Ramirez-Labrada A, de Miguel D, Benito R, Miranda P, Fernández A, Domingo JM, Serrano L, Yuste C, Villanueva-Saz S, Paño-Pardo JR, Pardo J.

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SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response

Oh SJ, Shin OS.

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SARS-CoV-2 Infection Is Asymptomatic in Nearly Half of Adults with Robust Anti-Spike Protein Receptor-Binding Domain Antibody Response

Tsitsilonis OE, Paraskevis D, Lianidou E, Terpos E, Akalestos A, Pierros V, Kostaki EG, Kastritis E, Moutsatsou P, Politou M, Scorilas A, Sphicopoulos T, Thomaidis N, Trougakos IP, Tsakris A, Voulgaris N, Daskalaki CC, Evangelakou Z, Fouki C, Gianniou DD, Gumeni S, Kostopoulos IV, Manola MS, Orologas-Stavrou N, Panteli C, Papanagnou ED, Rousakis P, Sklirou AD, Smilkou S, Stergiopoulou D, Tsiodras S, Dimopoulos MA, Sfikakis PP.

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Identification of Potential SARS-CoV-2 Main Protease and Spike Protein Inhibitors from the Genus Aloe: An In Silico Study for Drug Development

Abouelela ME, Assaf HK, Abdelhamid RA, Elkhyat ES, Sayed AM, Oszako T, Belbahri L, El Zowalaty AE, Abdelkader MSA.

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One Health Approach to Zoonotic Parasites: Molecular Detection of Intestinal Protozoans in an Urban Population of Norway Rats, Rattus norvegicus, in Barcelona, Spain

Galán-Puchades MT, Trelis M, Sáez-Durán S, Cifre S, Gosálvez C, Sanxis-Furió J, Pascual J, Bueno-Marí R, Franco S, Peracho V, Montalvo T, Fuentes MV.

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Rutin and flavone analogs as prospective SARS-CoV-2 main protease inhibitors: In silico drug discovery study

Ibrahim MAA, Mohamed EAR, Abdelrahman AHM, Allemailem KS, Moustafa MF, Shawky AM, Mahzari A, Hakami AR, Abdeljawaad KAA, Atia MAM.

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Molecular epidemiology analysis of early variants of SARS-CoV-2 reveals the potential impact of mutations P504L and Y541C (NSP13) in the clinical COVID-19 outcomes

Cao C, He L, Tian Y, Qin Y, Sun H, Ding W, Gui L, Wu P.

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Proteinase K treatment in absence of RNA isolation classical procedures is a quick and cheaper alternative for SARS-CoV-2 molecular detection

Mallmann L, Hermann BS, Schallenberger K, Demoliner M, Eisen AKA, Heldt FH, Gularte JS, Hansen AW, de Almeida PR, Weber MN, Spilki FR, Fleck JD.

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Inspecting the mechanism of fragment hit binding on SARS-CoV-2 Mpro by using supervised molecular dynamics (SuMD) simulations

Bissaro M, Bolcato G, Pavan M, Bassani D, Sturlese M, Moro S.

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Novel mutations in NSP-1 and PLPro of SARS-CoV-2 NIB-1 genome mount for effective therapeutics

Hossain MU, Bhattacharjee A, Emon MTH, Chowdhury ZM, Ahammad I, Mosaib MG, Moniruzzaman M, Rahman MH, Islam MN, Ahmed I, Amin MR, Rashed A, Das KC, Keya CA, Salimullah M.

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In silico characterization of mutations circulating in SARS-CoV-2 structural proteins

Periwal N, Rathod SB, Pal R, Sharma P, Nebhnani L, Barnwal RP, Arora P, Srivastava KR, Sood V.

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Discovery of Potent Covid-19 Main Protease Inhibitors using Integrated Drug Repurposing Strategy

Kumar TM, Rohini K, James N, Shanthi V, Ramanathan K.

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In silico approach of secondary metabolites from Brazilian herbal medicines to search for potential drugs against SARS-CoV-2

Amparo TR, Seibert JB, Almeida TC, Costa FSF, Silveira BM, da Silva GN, Dos Santos ODH, de Souza GHB.

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Analysis of SARS-CoV-2 genomic epidemiology reveals disease transmission coupled to variant emergence and allelic variation

Bandoy DJDR, Weimer BC.

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Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 main protease complexes reveal the role of lateral pocket in enhancing the ligand affinity

Weng YL, Naik SR, Dingelstad N, Lugo MR, Kalyaanamoorthy S, Ganesan A.

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Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD.

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Author Correction: Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Ou X, Liu Y, Lei X, Li P, Mi D, Ren L, Guo L, Guo R, Chen T, Hu J, Xiang Z, Mu Z, Chen X, Chen J, Hu K, Jin Q, Wang J, Qian Z.

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Coding-Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Gilgit, Pakistan

Javed A, Niazi SK, Ghani E, Yamin M, Saqib M, Janjua HA, Zohaib A.

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Genome Sequence of a SARS-CoV-2 Strain from a COVID-19 Clinical Sample from the Khagrachari District of Bangladesh

Hoq MI, Bhuiyan RH, Rahman MKR, Hossen I, Rudra S, Hossain MA, Paul S, Faruq MO, Faruque MO, Masud HMAA.

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Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA

Forsythe HM, Galvan JR, Yu Z, Pinckney S, Reardon P, Cooley RB, Zhu P, Rolland AD, Prell JS, Barbar E.

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Protein Footprinting, Conformational Dynamics, and Core Interface-Adjacent Neutralization "Hotspots" in the SARS-CoV-2 Spike Protein Receptor Binding Domain/Human ACE2 Interaction

Narang D, James DA, Balmer MT, Wilson DJ.

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Computational epitope map of SARS-CoV-2 spike protein

Sikora M, von Bülow S, Blanc FEC, Gecht M, Covino R, Hummer G.

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Molecular profile of oral fluid in new coronavirus infection

Gilmiyarova FN, Gusyakova OA, Konstantinov DY, Selezneva IA, Borodina IA, Kolotyeva NA, Konstantinova EA, Tlustenko VS, Lebedeva SS, Temnik EI, Remizov VV.

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Sequencing of SARS-CoV-2 genome using different nanopore chemistries

González-Recio O, Gutiérrez-Rivas M, Peiró-Pastor R, Aguilera-Sepúlveda P, Cano-Gómez C, Jiménez-Clavero MÁ, Fernández-Pinero J.

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A rapid assessment of wastewater for genomic surveillance of SARS-CoV-2 variants at sewershed scale in Louisville, KY

Fuqua JL, Rouchka EC, Waigel S, Sokoloski K, Chung D, Zacharias W, Zhang M, Chariker J, Talley D, Santisteban I, Varsani A, Moyer S, Holm RH, Yeager RA, Smith T, Bhatnagar A.

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SARS-CoV-2 genome sequencing from COVID-19 in Ecuadorian patients: a whole country analysis

Márquez S, Prado-Vivar B, José Guadalupe J, Becerra-Wong M, Gutierrez B; Clinical COVID-19 Ecuador Consortium, Fernández-Cadena JC, Andrade-Molina D, Morey-Leon G, Moncayo M, Guevara R, Coloma J, Trueba G, Grunauer M, Barragán V, Rojas-Silva P, Cárdenas P.

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TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform

Peiffer AL, Garlick JM, Wu Y, Soellner MB, Brooks CL, Mapp AK.

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Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2

Dicken SJ, Murray MJ, Thorne LG, Reuschl AK, Forrest C, Ganeshalingham M, Muir L, Kalemera MD, Palor M, McCoy LE, Jolly C, Towers GJ, Reeves MB, Grove J.

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Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD.

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White Button Mushroom (Agaricus bisporus) Interrupts Tissue AR-TMPRSS2 Expression and Attenuates Pro-inflammatory Cytokines in C57BL/6 Mice: Implication for COVID-19 Dietary Intervention

Chen S, Wang X, Ha D, Yoshitake R.

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Stability of SARS-CoV-2 Spike G614 Variant Surpasses That of the D614 Variant after Cold Storage

Huang SY, Kung YA, Huang PN, Chang SY, Gong YN, Han YJ, Chiang HJ, Liu KT, Lee KM, Chang CY, Chang CC, Huang CG, Shih SR.

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SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration

Idrees D, Kumar V.

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SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera

Kuzmina A, Khalaila Y, Voloshin O, Keren-Naus A, Boehm-Cohen L, Raviv Y, Shemer-Avni Y, Rosenberg E, Taube R.

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Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

Cerutti G, Guo Y, Zhou T, Gorman J, Lee M, Rapp M, Reddem ER, Yu J, Bahna F, Bimela J, Huang Y, Katsamba PS, Liu L, Nair MS, Rawi R, Olia AS, Wang P, Zhang B, Chuang GY, Ho DD, Sheng Z, Kwong PD, Shapiro L.

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A Highly Automated Mobile Laboratory for On-site Molecular Diagnostics in the COVID-19 Pandemic

Xing W, Wang J, Zhao C, Wang H, Bai L, Pan L, Li H, Wang H, Zhang Z, Lu Y, Chen X, Shan S, Wang D, Pan Y, Weng D, Zhou X, Huang R, He J, Jin R, Li W, Shang H, Zhong N, Cheng J.

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Estimation of secondary household attack rates for emergent spike L452R SARS-CoV-2 variants detected by genomic surveillance at a community-based testing site in San Francisco

Peng J, Liu J, Mann SA, Mitchell AM, Laurie MT, Sunshine S, Pilarowski G, Ayscue P, Kistler A, Vanaerschot M, Li LM, McGeever A, Chow ED, Marquez C, Nakamura R, Rubio L, Chamie G, Jones D, Jacobo J, Rojas S, Rojas S, Tulier-Laiwa V, Black D, Martinez J, Naso J, Schwab J, Petersen M, Havlir D, DeRisi J; IDseq Team.

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Dental workers in front-line of COVID-19: an in silico evaluation targeting their prevention

Sette-DE-Souza PH, Costa MJF, Amaral-Machado L, Araújo FADC, Almeida Filho AT, Lima LRA.

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Serological and Molecular Tests for COVID-19: a recent update

Mansourabadi AH, Sadeghalvad M, Mohammadi-Motlagh HR, Amirzargar A.

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A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells

Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Kocurek KI, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Yoon MC, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Hook V, Frueh F, Hurst BL, Wang H, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH.

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An Integrative in Silico Drug Repurposing Approach for Identification of Potential Inhibitors of SARS-CoV-2 Main Protease

Djokovic N, Ruzic D, Djikic T, Cvijic S, Ignjatovic J, Ibric S, Baralic K, Buha Djordjevic A, Curcic M, Djukic-Cosic D, Nikolic K.

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Multiple Sites on SARS-CoV-2 Spike Protein are Susceptible to Proteolysis by Cathepsins B, K, L, S, and V

Bollavaram K, Leeman TH, Lee MW, Kulkarni A, Upshaw SG, Yang J, Song H, Platt MO.

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Pharmacoinformatics-based identification of transmembrane protease serine-2 inhibitors from Morus Alba as SARS-CoV-2 cell entry inhibitors

Shakya A, Chikhale RV, Bhat HR, Alasmary FA, Almutairi TM, Ghosh SK, Alhajri HM, Alissa SA, Nagar S, Islam MA.

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Adsorption of SARS-CoV-2 Spike Protein S1 at Oxide Surfaces Studied by High-Speed Atomic Force Microscopy

Xin Y, Grundmeier G, Keller A.

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An in silico analysis of effective siRNAs against COVID-19 by targeting the leader sequence of SARS-CoV-2

Pandey AK, Verma S.

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Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations

Zhang CH, Stone EA, Deshmukh M, Ippolito JA, Ghahremanpour MM, Tirado-Rives J, Spasov KA, Zhang S, Takeo Y, Kudalkar SN, Liang Z, Isaacs F, Lindenbach B, Miller SJ, Anderson KS, Jorgensen WL.

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Drug Repurposing of Itraconazole and Estradiol Benzoate against COVID-19 by Blocking SARS-CoV-2 Spike Protein-Mediated Membrane Fusion

Yang C, Pan X, Huang Y, Cheng C, Xu X, Wu Y, Xu Y, Shang W, Niu X, Wan Y, Li Z, Zhang R, Liu S, Xiao G, Xu W.

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In silico studies of selected multi-drug targeting against 3CLpro and nsp12 RNA-dependent RNA-polymerase proteins of SARS-CoV-2 and SARS-CoV

Udofia IA, Gbayo KO, Oloba-Whenu OA, Ogunbayo TB, Isanbor C.

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Replicating bacterium-vectored vaccine expressing SARS-CoV-2 Membrane and Nucleocapsid proteins protects against severe COVID-19-like disease in hamsters

Jia Q, Bielefeldt-Ohmann H, Maison RM, Masleša-Galić S, Cooper SK, Bowen RA, Horwitz MA.

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Integrated characterization of SARS-CoV-2 genome, microbiome, antibiotic resistance and host response from single throat swabs

Lu B, Yan Y, Dong L, Han L, Liu Y, Yu J, Chen J, Yi D, Zhang M, Deng X, Wang C, Wang R, Wang D, Wei H, Liu D, Yi C.

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Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions

Day CJ, Bailly B, Guillon P, Dirr L, Jen FE, Spillings BL, Mak J, von Itzstein M, Haselhorst T, Jennings MP.

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Covid-19: India sees new spike in cases despite vaccine rollout

Bhuyan A.

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Design and synthesis of novel phe-phe hydroxyethylene derivatives as potential coronavirus main protease inhibitors

Khorsandi Z, Afshinpour M, Molaei F, Askandar RH, Keshavarzipour F, Abbasi M, Sadeghi-Aliabadi H.

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SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2

Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY.

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A Recombinant Fragment of Human Surfactant Protein D Binds Spike Protein and Inhibits Infectivity and Replication of SARS-CoV-2 in Clinical Samples

Madan T, Biswas B, Varghese PM, Subedi R, Pandit H, Idicula-Thomas S, Kundu I, Rooge S, Agarwal R, Tripathi DM, Kaur S, Gupta E, Gupta SK, Kishore U.

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Lead Discovery of SARS-CoV-2 Main Protease Inhibitors through Covalent Docking-Based Virtual Screening

Amendola G, Ettari R, Previti S, Di Chio C, Messere A, Di Maro S, Hammerschmidt SJ, Zimmer C, Zimmermann RA, Schirmeister T, Zappalà M, Cosconati S.

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Comprehensive Comparative Genomic and Microsatellite Analysis of SARS, MERS, BAT-SARS and COVID-19 Coronaviruses

Rehman HA, Ramzan F, Basharat Z, Shakeel M, Khan MUG, Khan IA.

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Mass molecular testing for COVID19 using NGS-based technology and a highly scalable workflow

de Mello Malta F, Amgarten D, Val FC, Cervato MC, de Azevedo BMC, de Souza Basqueira M, Dos Santos Alves CO, Nobrega MS, de Souza Reis R, Sebe P, Gretschischkin MC, de Oliveira DDC, Nakamura CNI, Chazanas PLN, Pinho JRR.

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The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

Cubuk J, Alston JJ, Incicco JJ, Singh S, Stuchell-Brereton MD, Ward MD, Zimmerman MI, Vithani N, Griffith D, Wagoner JA, Bowman GR, Hall KB, Soranno A, Holehouse AS.

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Protein-ligand Docking Simulations with AutoDock4 Focused on the Main Protease of SARS-CoV-2

de Azevedo Junior WF, Bitencourt-Ferreira G, Godoy JR, Adriano HMA, Dos Santos Bezerra WA, Dos Santos Soares AM.

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Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19

Rodriguez C, de Prost N, Fourati S, Lamoureux C, Gricourt G, N'debi M, Canoui-Poitrine F, Désveaux I, Picard O, Demontant V, Trawinski E, Lepeule R, Surgers L, Vindrios W, Lelièvre JD, Mongardon N, Langeron O, Cohen JL, Mekontso-Dessap A, Woerther PL, Pawlotsky JM.

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SARS-CoV-2 infection: molecular mechanisms of severe outcomes to suggest therapeutics

Hartog N, Faber W, Frisch A, Bauss J, Bupp CP, Rajasekaran S, Prokop JW.

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Phylogenomic tracing of asymptomatic transmission in a COVID-19 outbreak

Zhang J, Ding N, Song Y, Song R, Pan Y, Wang L, Yan S, Wang Q, Ma S, Wei L, Yu F, Lu L, Zhang F, Chen C, Zeng H.

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Phylogenomic analysis of COVID-19 summer and winter outbreaks in Hong Kong: An observational study

Chan WM, Ip JD, Chu AW, Tse H, Tam AR, Li X, Kwan MY, Yau YS, Leung WS, Chik TS, To WK, Ng AC, Yip CC, Poon RW, Chan KH, Wong SC, Choi GK, Lung DC, Cheng VC, Hung IF, Yuen KY, To KK.

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Comparative analysis of mutational hotspots in the spike protein of SARS-CoV-2 isolates from different geographic origins

Lee S, Lee MK, Na H, Ahn J, Hong G, Lee Y, Park J, Kim Y, Kim YT, Kim CK, Lim HS, Lee KR.

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Insights on the Structural Variations of the Furin-Like Cleavage Site Found Among the December 2019-July 2020 SARS-CoV-2 Spike Glycoprotein: A Computational Study Linking Viral Evolution and Infection

Cueno ME, Ueno M, Iguchi R, Harada T, Miki Y, Yasumaru K, Kiso N, Wada K, Baba K, Imai K.

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Development of a Colloidal Gold-Based Immunochromatographic Strip for Rapid Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein

Li G, Wang A, Chen Y, Sun Y, Du Y, Wang X, Ding P, Jia R, Wang Y, Zhang G.

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Synthesis, Molecular Docking, In Silico ADME Predictions, and Toxicity Studies of N-Substituted-5-(4-Chloroquinolin-2-yl)-1,3,4-Thiadiazol-2-Amine Derivatives as COVID-19 Inhibitors

Hanaa S Mohamed, El-Serwy WS, El-Serwy WS.

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Docking and in silico toxicity assessment of Arthrospira compounds as potential antiviral agents against SARS-CoV-2

Petit L, Vernès L, Cadoret JP.

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In silico studies on stilbenolignan analogues as SARS-CoV-2 Mpro inhibitors

Cetin A.

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Identification of non-covalent SARS-CoV-2 main protease inhibitors by a virtual screen of commercially available drug-like compounds

Zhang L, Howland M, Hilgenfeld R, Anderson MO, Eagon S.

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In-silico screening for identification of potential inhibitors against SARS-CoV-2 transmembrane serine protease 2 (TMPRSS2)

Barge S, Jade D, Gosavi G, Talukdar NC, Borah J.

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SARS-CoV-2 spike protein binding selectively accelerates substrate-specific catalytic activity of ACE2

Kiseleva AA, Troisi EM, Hensley SE, Kohli RM, Epstein JA.

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Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

Zhao MM, Yang WL, Yang FY, Zhang L, Huang WJ, Hou W, Fan CF, Jin RH, Feng YM, Wang YC, Yang JK.

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The development and kinetics of functional antibody-dependent cell-mediated cytotoxicity (ADCC) to SARS-CoV-2 spike protein

Chen X, Rostad CA, Anderson LJ, Sun HY, Lapp SA, Stephens K, Hussaini L, Gibson T, Rouphael N, Anderson EJ.

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Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution

Jungreis I, Nelson CW, Ardern Z, Finkel Y, Krogan NJ, Sato K, Ziebuhr J, Stern-Ginossar N, Pavesi A, Firth AE, Gorbalenya AE, Kellis M.

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Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: A computational approach

Kwarteng A, Asiedu E, Sylverken AA, Larbi A, Sakyi SA, Asiedu SO.

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Are saliva and deep throat sputum as reliable as common respiratory specimens for SARS-CoV-2 detection? A systematic review and meta-analysis

Khiabani K, Amirzade-Iranaq MH.

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Dipeptidylpeptidase-4 levels and DPP4 gene polymorphisms in patients with COVID-19. Association with disease and with severity

Posadas-Sánchez R, Sánchez-Muñoz F, Guzmán-Martín CA, Hernández-Díaz Couder A, Rojas-Velasco G, Fragoso JM, Vargas-Alarcón G.

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Rapid whole-genome sequencing to inform COVID-19 outbreak response in Vietnam

Chau NVV, Hong NTT, Ngoc NM, Anh NT, Trieu HT, Nhu LNT, Yen LM, Minh NNQ, Phong NT, Truong NT, Huong LTT, Tu TNH, Hung LM, Thanh TT, Dung NT, Dung NT, Thwaites G, Van Tan L; for OUCRU COVID-19 research group.

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Point of care ultrasound (POCUS) in diagnosis of proximal deep vein thrombosis among COVID-19 hospitalized patients with a high rate of low molecular weight heparin prophylaxis

García-Ceberino PM, Faro-Míguez N, Beltrán-Ávila FJ, Fernández-Reyes D, Gallardo-Muñoz I, Guirao-Arrabal E.

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Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Chen RE, Shi PY, Carnahan RH, Thackray LB, Diamond MS, Crowe JE Jr.

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Generation of WAe001-A-58 human embryonic stem cell line with inducible expression of the SARS-CoV-2 nucleocapsid protein

Wu F, Chen Y, You K, Tan S, Xu Y, Wang PH, Liu S, Li YX.

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In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect

Haddad-Boubaker S, Othman H, Touati R, Ayouni K, Lakhal M, Ben Mustapha I, Ghedira K, Kharrat M, Triki H.

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Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2

Zhao D, Xu W, Zhang X, Wang X, Ge Y, Yuan E, Xiong Y, Wu S, Li S, Wu N, Tian T, Feng X, Shu H, Lang P, Li J, Zhu F, Shen X, Li H, Li P, Zeng J.

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Genomic variation and epidemiology of SARS-CoV-2 importation and early circulation in Israel

Zuckerman NS, Bucris E, Drori Y, Erster O, Sofer D, Pando R, Mendelson E, Mor O, Mandelboim M.

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Analysis of the SARS-CoV-2-host protein interaction network reveals new biology and drug candidates: focus on the spike surface glycoprotein and RNA polymerase

Sokullu E, Pinard M, Gauthier MS, Coulombe B.

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Chlorogenic acid, a natural product as potential inhibitor of COVID-19: virtual screening experiment based on network pharmacology and molecular docking

Wang WX, Zhang YR, Luo SY, Zhang YS, Zhang Y, Tang C.

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QT prolongation associated with hydroxychloroquine and protease inhibitors in COVID-19

Koh HM, Chong PF, Tan JN, Chidambaram SK, Chua HJ.

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Spike vs nucleocapsid SARS-CoV-2 antigen detection: application in nasopharyngeal swab specimens

Barlev-Gross M, Weiss S, Ben-Shmuel A, Sittner A, Eden K, Mazuz N, Glinert I, Bar-David E, Puni R, Amit S, Kriger O, Schuster O, Alcalay R, Makdasi E, Epstein E, Noy-Porat T, Rosenfeld R, Achdout H, Mazor O, Israely T, Levy H, Mechaly A.

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Clinical, Serological, Whole Genome Sequence Analyses to Confirm SARS-CoV-2 Reinfection in Patients From Mumbai, India

Shastri J, Parikh S, Agrawal S, Chatterjee N, Pathak M, Chaudhary S, Sharma C, Kanakan A, A V, Srinivasa Vasudevan J, Maurya R, Fatihi S, Thukral L, Agrawal A, Pinto L, Pandey R, Sunil S.

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The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic

Shah P, Canziani GA, Carter EP, Chaiken I.

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In silico investigation of critical binding pattern in SARS-CoV-2 spike protein with angiotensin-converting enzyme 2

Jafary F, Jafari S, Ganjalikhany MR.

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Genome Sequences of Three SARS-CoV-2 P.1 Strains Identified from Patients Returning from Brazil to Italy

Delli Compagni E, Jurisic L, Caporale M, Bacà F, Scialabba S, Fanì S, Perullo A, Toro M, Marchegiano A, Martino M, Di Giacomo D, Romualdi T, Verzulli S, Ciarrocchi E, Secondini B, Di Giuseppe M, Irelli R, Di Lorenzo A, Valleriani F, Berjaoui S, Puglia I, Curini V, Mangone I, Lorusso A.

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Near-Complete Genome Sequence of a SARS-CoV-2 VOC 202012/01 Strain in Peru

Padilla-Rojas C, Barcena-Flores L, Vega-Chozo K, Galarza-Perez M, Bailon-Calderon H, Lope-Pari P, Balbuena-Torres J, Huaringa-Nuñez M, Caceres-Rey O, Rojas-Serrano N.

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Fibrinolysis Shutdown in COVID-19: Clinical Manifestations, Molecular Mechanisms, and Therapeutic Implications

Meizoso JP, Moore HB, Moore EE.

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In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase

Celik I, Erol M, Duzgun Z.

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Isatin-based virtual high throughput screening, molecular docking, DFT, QM/MM, MD and MM-PBSA study of novel inhibitors of SARS-CoV-2 main protease

Varadharajan V, Arumugam GS, Shanmugam S.

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Epidemiological, clinical and genomic snapshot of the first 100 B.1.1.7 SARS-CoV-2 cases in Madrid

Pérez-Lago L, Sola Campoy PJ, Buenestado-Serrano S, Catalán P, Estévez A, de la Cueva VM, López MG, Herranz M, Suárez-González J, Alcalá L, Comas I, Candelas FG, Muñoz P, de Viedma DG.

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Aripiprazole as a Candidate Treatment of COVID-19 Identified Through Genomic Analysis

Crespo-Facorro B, Ruiz-Veguilla M, Vázquez-Bourgon J, Sánchez-Hidalgo AC, Garrido-Torres N, Cisneros JM, Prieto C, Sainz J.

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Revealing the mechanism of SARS-CoV-2 spike protein binding with ACE2

Xie Y, Du D, Karki CB, Guo W, Lopez-Hernandez AE, Sun S, Juarez BY, Li H, Wang J, Li L.

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Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

Zhu H, Chen CZ, Sakamuru S, Zhao J, Ngan DK, Simeonov A, Hall MD, Xia M, Zheng W, Huang R.

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Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients

Li Y, Ma ML, Lei Q, Wang F, Hong W, Lai DY, Hou H, Xu ZW, Zhang B, Chen H, Yu C, Xue JB, Zheng YX, Wang XN, Jiang HW, Zhang HN, Qi H, Guo SJ, Zhang Y, Lin X, Yao Z, Wu J, Sheng H, Zhang Y, Wei H, Sun Z, Fan X, Tao SC.

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Unveiling the Molecular Structure of Antimalarial Drugs Chloroquine and Hydroxychloroquine in Solution through Analysis of (1)H NMR Chemical Shifts

Hernandes IS, Da Silva HC, Dos Santos HF, De Almeida WB.

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Study on the mechanism of active components of Liupao tea on 3CL(pro) based on HPLC-DAD fingerprint and molecular docking technique

Ni WJ, Chen XX, Wei SY, Lan LL, Qiu RJ, Ling YP, Zhou DS, Wu ZM, Cao ZH, Yu CP, Zeng Y.

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In silico screening of therapeutic potentials from Strychnos nux-vomica against the dimeric main protease (M(pro)) structure of SARS-CoV-2

Kumar B, Parasuraman P, Murthy TPK, Murahari M, Chandramohan V.

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Plant-derived chemicals as potential inhibitors of SARS-CoV-2 main protease (6LU7), a virtual screening study

Sisakht M, Mahmoodzadeh A, Darabian M.

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Monoclonal antibodies capable of binding SARS-CoV-2 spike protein receptor-binding motif specifically prevent GM-CSF induction

Qiang X, Zhu S, Li J, Chen W, Yang H, Wang P, Tracey KJ, Wang H.

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Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-González A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Sanchez San Martin C, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Kumar GR, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi J, Simoneau CR, McMahon S, Lidsky PV, Xiao Y, Hemarajata P, Green NM, Espinosa A, Kath C, Haw M, Bell J, Hacker JK, Hanson C, Wadford DA, Anaya C, Ferguson D, Lareau LF, Frankino PA, Shivram H, Wyman SK, Ott

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Magnesium Treatment on Methylation Changes of Transmembrane Serine Protease 2 (TMPRSS2)

Fan L, Zhu X, Zheng Y, Zhang W, Seidner DL, Ness R, Murff HJ, Yu C, Huang X, Shrubsole MJ, Hou L, Dai Q.

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High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection

Winkley K, Koseva B, Banerjee D, Cheung W, Selvarangan R, Pastinen T, Grundberg E.

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Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay

Xia Z, Sacco MD, Ma C, Townsend JA, Kitamura N, Hu Y, Ba M, Szeto T, Zhang X, Meng X, Zhang F, Xiang Y, Marty MT, Chen Y, Wang J.

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Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-Cov-2 variants

Tchesnokova V, Kulakesara H, Larson L, Bowers V, Rechkina E, Kisiela D, Sledneva Y, Choudhury D, Maslova I, Deng K, Kutumbaka K, Geng H, Fowler C, Greene D, Ralston J, Samadpour M, Sokurenko E.

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Identification of ACE2 mutations that modulate SARS-CoV-2 spike binding across multiple mammalian species

Heinzelman P, Romero PA.

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DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing

Lagerborg KA, Normandin E, Bauer MR, Adams G, Figueroa K, Loreth C, Gladden-Young A, Shaw B, Pearlman L, Shenoy ES, Hooper D, Pierce VM, Zachary KC, Park DJ, MacInnis BL, Lemieux JE, Sabeti PC, Reilly SK, Siddle KJ.

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SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway

Khan S, Shafiei MS, Longoria C, Schoggins J, Savani RC, Zaki H.

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Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity

Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Saunders K, Edwards RJ, Haynes BF, Henderson RC, Acharya P.

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Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice

Martinez DR, Schaefer A, Leist SR, De la Cruz G, West A, Atochina-Vasserman EN, Parks R, Barr M, Li D, Yount B, Saunders KO, Weissman D, Haynes BF, Montgomery SA, Baric RS.

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The N501Y spike substitution enhances SARS-CoV-2 transmission

Liu Y, Liu J, Plante KS, Plante JA, Xie X, Zhang X, Ku Z, An Z, Scharton D, Schindewolf C, Menachery VD, Shi PY, Weaver SC.

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Site-specific steric control of SARS-CoV-2 spike glycosylation

Allen JD, Chawla H, Samsudin F, Zuzic L, Shivgan AT, Watanabe Y, He WT, Callaghan S, Song G, Yong P, Brouwer PJM, Song Y, Cai Y, Duyvesteyn HME, Malinauskas T, Kint J, Pino P, Wurm MJ, Frank M, Chen B, Stuart DI, Sanders RW, Andrabi R, Burton DR, Li S, Bond PJ, Crispin M.

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Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike protein

Alai S, Gujar N, Joshi M, Gautam M, Gairola S.

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A molecular docking study of SARS-CoV-2 main protease against phytochemicals of Boerhavia diffusa Linn. for novel COVID-19 drug discovery

Rutwick Surya U, Praveen N.

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Coronil, a Tri-Herbal Formulation, Attenuates Spike-Protein-Mediated SARS-CoV-2 Viral Entry into Human Alveolar Epithelial Cells and Pro-Inflammatory Cytokines Production by Inhibiting Spike Protein-ACE-2 Interaction

Balkrishna A, Haldar S, Singh H, Roy P, Varshney A.

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Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex

Dhillon A, Deme JC, Furlong E, Roem D, Jongerius I, Johnson S, Lea SM.

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Special issue: Modeling the biological, epidemiological, immunological, molecular, virological aspects of COVID-19

Gao D, He D.

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Landscape of SARS-CoV-2 spike protein-interacting cells in human tissues

Zheng B, Yuan M, Ma Q, Wang S, Tan Y, Xu Y, Ye J, Gao Y, Sun X, Yang Z, Xu P, Kong L, Wu X, Xu Q.

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Whole-genome sequencing of SARS-CoV-2 reveals the detection of G614 variant in Pakistan

Umair M, Ikram A, Salman M, Khurshid A, Alam M, Badar N, Suleman R, Tahir F, Sharif S, Montgomery J, Whitmer S, Klena J.

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Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography

Kneller DW, Phillips G, Weiss KL, Zhang Q, Coates L, Kovalevsky A.

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Tinker-HP: Accelerating Molecular Dynamics Simulations of Large Complex Systems with Advanced Point Dipole Polarizable Force Fields Using GPUs and Multi-GPU Systems

Adjoua O, Lagardère L, Jolly LH, Durocher A, Very T, Dupays I, Wang Z, Inizan TJ, Célerse F, Ren P, Ponder JW, Piquemal JP.

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Binding and drug displacement study of colchicine and bovine serum albumin in presence of azithromycin using multispectroscopic techniques and molecular dynamic simulation

Wani TA, Bakheit AH, Al-Majed AA, Altwaijry N, Baquaysh A, Aljuraisy A, Zargar S.

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SARS-CoV-2 main protease inhibition by compounds isolated from Luffa cylindrica using molecular docking

Cao TQ, Kim JA, Woo MH, Min BS.

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Structural insights on the interaction potential of natural leads against major protein targets of SARS-CoV-2: Molecular modelling, docking and dynamic simulation studies

Skariyachan S, Gopal D, Muddebihalkar AG, Uttarkar A, Niranjan V.

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Variable routes to genomic and host adaptation among coronaviruses

Montoya V, McLaughlin A, Mordecai GJ, Miller RL, Joy JB.

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DNA vaccine candidate encoding SARS-CoV-2 spike proteins elicited potent humoral and Th1 cell-mediated immune responses in mice

Prompetchara E, Ketloy C, Tharakhet K, Kaewpang P, Buranapraditkun S, Techawiwattanaboon T, Sathean-Anan-Kun S, Pitakpolrat P, Watcharaplueksadee S, Phumiamorn S, Wijagkanalan W, Patarakul K, Palaga T, Ruxrungtham K.

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Modelling the association between COVID-19 transmissibility and D614G substitution in SARS-CoV-2 spike protein: using the surveillance data in California as an example

Zhao S, Lou J, Cao L, Zheng H, Chong MKC, Chen Z, Zee BCY, Chan PKS, Wang MH.

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Reinfection or Reactivation: Genome based two distinct SNP profile of SARS-CoV2 re-positivity in an Indian case

Dhar MS, Vivekanand A, Uppili B, Tyagi N, Sharma P, Tiwari S, Vs R, Marwal R, Kanakan A, Khan AM, Pandey R, Jais M, Gogoi S, Shewale A, Nale T, Kabra S, Faruq M, Singh S, Agrawal A, Rakshit P.

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Genomic diversity of SARS-CoV-2 during early introduction into the Baltimore-Washington metropolitan area

Thielen PM, Wohl S, Mehoke T, Ramakrishnan S, Kirsche M, Falade-Nwulia O, Trovão NS, Ernlund A, Howser C, Sadowski N, Morris CP, Hopkins M, Schwartz M, Fan Y, Gniazdowski V, Lessler J, Sauer L, Schatz MC, Evans JD, Ray SC, Timp W, Mostafa HH.

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Evaluation of the effects of chlorhexidine and several flavonoids as antiviral purposes on SARS-CoV-2 main protease: molecular docking, molecular dynamics simulation studies

Tatar G, Salmanli M, Dogru Y, Tuzuner T.

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On the search for COVID-19 therapeutics: identification of potential SARS-CoV-2 main protease inhibitors by virtual screening, pharmacophore modeling and molecular dynamics

Hassan A, Arafa RK.

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Phylogenic analysis of coronavirus genome and molecular studies on potential anti-COVID-19 agents from selected FDA-approved drugs

Ishola AA, Adewole KE, Tijjani H, Abdulai SI, Asogwa NT.

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Repurposing of anticancer phytochemicals for identifying potential fusion inhibitor for SARS-CoV-2 using molecular docking and molecular dynamics (MD) simulations

Patel CN, Goswami D, Sivakumar PK, Pandya HA.

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Lack of Molecular Mimicry between Nonhuman Primates and Infectious Pathogens: The Possible Genetic Bases

Kanduc D.

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Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein

Mustafa Z, Zhanapiya A, Kalbacher H, Burster T.

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SARS-CoV-2 Genome from the Khyber Pakhtunkhwa Province of Pakistan

Khan MT, Ali S, Khan AS, Muhammad N, Khalil F, Ishfaq M, Irfan M, Al-Sehemi AG, Muhammad S, Malik A, Khan TA, Wei DQ.

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Evaluation of flavonoids as 2019-nCoV cell entry inhibitor through molecular docking and pharmacological analysis

Bhowmik D, Nandi R, Prakash A, Kumar D.

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Computational analysis of functional monomers used in molecular imprinting for promising COVID-19 detection

Cubuk H, Ozbil M, Cakir Hatir P.

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Genomic epidemiology of a densely sampled COVID-19 outbreak in China

Geidelberg L, Boyd O, Jorgensen D, Siveroni I, Nascimento FF, Johnson R, Ragonnet-Cronin M, Fu H, Wang H, Xi X, Chen W, Liu D, Chen Y, Tian M, Tan W, Zai J, Sun W, Li J, Li J, Volz EM, Li X, Nie Q.

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Molecular Docking Reveals Ivermectin and Remdesivir as Potential Repurposed Drugs Against SARS-CoV-2

Eweas AF, Alhossary AA, Abdel-Moneim AS.

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Molecular Mechanism of Action of Repurposed Drugs and Traditional Chinese Medicine Used for the Treatment of Patients Infected With COVID-19: A Systematic Scoping Review

Lem FF, Opook F, Lee DJH, Chee FT, Lawson FP, Chin SN.

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In-Silico Drug Designing of Spike Receptor with Its ACE2 Receptor and Nsp10/Nsp16 MTase Complex Against SARS-CoV-2

Siddiqa MA, Rao DS, Suvarna G, Chennamachetty VK, Verma MK, Rao MVR.

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The Use Of Ultrapure Molecular Hydrogen Enriched With Atomic Hydrogen In Apparatuses Of Artificial Lung Ventilation In The Fight Against Virus COVID-19

Zolotarenko AD, Zolotarenko AD, Veziroglu A, Veziroglu TN, Shvachko NA, Pomytkin AP, Gavrylyuk NA, Schur DV, Ramazanov TS, Gabdullin MT.

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Analytical performances of the point-of-care SIENNAâ„¢ COVID-19 Antigen Rapid Test for the detection of SARS-CoV-2 nucleocapsid protein in nasopharyngeal swabs: A prospective evaluation during the COVID-19 second wave in France

Mboumba Bouassa RS, Veyer D, Péré H, Bélec L.

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In silico Nigellidine (N. sativa) bind to viral spike/active-sites of ACE1/2, AT1/2 to prevent COVID-19 induced vaso-tumult/vascular-damage/comorbidity

Maiti S, Banerjee A, Kanwar M.

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Host-dependent molecular factors mediating SARS-CoV-2 infection to gain clinical insights for developing effective targeted therapy

Shafi G, Desai S, Srinivasan K, Ramesh A, Chaturvedi R, Uttarwar M.

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SARS-CoV-2 spike protein interacts with and activates TLR41

Zhao Y, Kuang M, Li J, Zhu L, Jia Z, Guo X, Hu Y, Kong J, Yin H, Wang X, You F.

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Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

van der Lubbe JEM, Rosendahl Huber SK, Vijayan A, Dekking L, van Huizen E, Vreugdenhil J, Choi Y, Baert MRM, Feddes-de Boer K, Izquierdo Gil A, van Heerden M, Dalebout TJ, Myeni SK, Kikkert M, Snijder EJ, de Waal L, Stittelaar KJ, Tolboom JTBM, Serroyen J, Muchene L, van der Fits L, Rutten L, Langedijk JPM, Barouch DH, Schuitemaker H, Zahn RC, Wegmann F.

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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

Wettstein L, Weil T, Conzelmann C, Müller JA, Groß R, Hirschenberger M, Seidel A, Klute S, Zech F, Prelli Bozzo C, Preising N, Fois G, Lochbaum R, Knaff PM, Mailänder V, Ständker L, Thal DR, Schumann C, Stenger S, Kleger A, Lochnit G, Mayer B, Ruiz-Blanco YB, Hoffmann M, Sparrer KMJ, Pöhlmann S, Sanchez-Garcia E, Kirchhoff F, Frick M, Münch J.

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Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates

He L, Lin X, Wang Y, Abraham C, Sou C, Ngo T, Zhang Y, Wilson IA, Zhu J.

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Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study

Zaferani Arani H, Dehghan Manshadi G, Atashi HA, Rezaei Nejad A, Ghorani SM, Abolghasemi S, Bahrani M, Khaledian H, Bozorg Savodji P, Hoseinian M, Kazemzade Bejandi A, Abolghasemi S.

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Mutations in spike protein and allele variations in ACE2 impact targeted therapy strategies against SARS-CoV-2

Shu CJ, Huang X, Tang HH, Mo DD, Zhou JW, Deng C.

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SARS-CoV-2 genomic analyses in cancer patients reveal elevated intrahost genetic diversity

Siqueira JD, Goes LR, Alves BM, de Carvalho PS, Cicala C, Arthos J, Viola JPB, de Melo AC, Soares MA.

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Investigation of One Familial Cluster of COVID-19 in Taiwan: Differentiation of Genetic Variation Among Isolates and Implications for Epidemiological Investigation and Surveillance by Genomic Assay

Jian MJ, Chung HY, Chang CK, Hsieh SS, Lin JC, Yeh KM, Chen CW, Chang FY, Chiu SK, Hung KS, Liu MT, Yang JR, Perng CL, Shang HS.

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Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish Model

Balkrishna A, Pokhrel S, Singh H, Joshi M, Mulay VP, Haldar S, Varshney A.

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Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2

Yan R, Zhang Y, Li Y, Ye F, Guo Y, Xia L, Zhong X, Chi X, Zhou Q.

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Prioritizing antiviral drugs against SARS-CoV-2 by integrating viral complete genome sequences and drug chemical structures

Peng L, Shen L, Xu J, Tian X, Liu F, Wang J, Tian G, Yang J, Zhou L.

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Perfect Match Genomic Landscape strategy: Refinement and customization of reference genomes

Palacios-Flores K, García-Sotelo J, Castillo A, Uribe C, Morales L, Boege M, Dávila G, Flores M, Palacios R.

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First Report of a SARS-CoV-2 Genome Sequence with a Spike His69-Val70 Deletion and an Asn439Lys Mutation in Morocco

Aanniz T, Ouadghiri M, Bendahou MA, Chemao-Elfihri MW, Chenaoui M, Dakka H, Allaoui A, Touzani O, Benaouda A, Belefquih B, Amzazi S, Belyamani L, Ibrahimi A.

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Structural and molecular perspectives of SARS-CoV-2

Kumar S, van Regenmortel MHV, Rivas AL, Saxena SK.

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Genomic surveillance of SARS-CoV-2 in the Republic of Congo

Ntoumi F, Mapanguy CCM, Tomazatos A, Pallerla SR, Linh LTK, Casadei N, Angelov A, Sonnabend M, Peter S, Kremsner PG, Velavan TP.

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Comparison of the Roche cobas 6800 SARS-CoV-2 test and the Taiwan CDC protocol for the molecular diagnosis of COVID-19

You HL, Lin MC, Lee CH.

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One-pot high-yield synthesis of Pd nanocubes for Pd-Ir nanocube-based immunoassay of nucleocapsid protein from SARS-CoV-2

Li J, Li Y.

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A comprehensive SARS-CoV-2 genomic analysis identifies potential targets for drug repurposing

Anand NM, Liya DH, Pradhan AK, Tayal N, Bansal A, Donakonda S, Jainarayanan AK.

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Membrane Nanoparticles Derived from ACE2-Rich Cells Block SARS-CoV-2 Infection

Wang C, Wang S, Chen Y, Zhao J, Han S, Zhao G, Kang J, Liu Y, Wang L, Wang X, Xu Y, Wang S, Huang Y, Wang J, Zhao J.

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Discrepant Results of Molecular RT-PCR Tests in Patients with COVID-19 infection

Antico A, Piera Panozzo M, Zoppelletto M, Di Giacomo V, Merola F, Bizzaro N.

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Cross-reactive antibody against human coronavirus OC43 spike protein correlates with disease severity in COVID-19 patients:a retrospective study

Guo L, Wang Y, Kang L, Hu Y, Wang L, Zhong J, Chen H, Ren L, Gu X, Wang G, Wang C, Dong X, Wu C, Han L, Wang Y, Fan G, Zou X, Li H, Xu J, Jin Q, Cao B, Wang J.

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Computational Mutagenesis at the SARS-CoV-2 Spike Protein/Angiotensin-Converting Enzyme 2 Binding Interface: Comparison with Experimental Evidence

Laurini E, Marson D, Aulic S, Fermeglia A, Pricl S.

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Discovery of Clioquinol and analogues as novel inhibitors of Severe Acute Respiratory Syndrome Coronavirus 2 infection, ACE2 and ACE2 - Spike protein interaction in vitro

Olaleye OA, Kaur M, Onyenaka C, Adebusuyi T.

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A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

Wang C, van Haperen R, Gutiérrez-Álvarez J, Li W, Okba NMA, Albulescu I, Widjaja I, van Dieren B, Fernandez-Delgado R, Sola I, Hurdiss DL, Daramola O, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ.

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Catalytic amplification by transition-state molecular switches for direct and sensitive detection of SARS-CoV-2

Sundah NR, Natalia A, Liu Y, Ho NRY, Zhao H, Chen Y, Miow QH, Wang Y, Beh DLL, Chew KL, Chan D, Tambyah PA, Ong CWM, Shao H.

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Immuno-informatics design of a multimeric epitope peptide based vaccine targeting SARS-CoV-2 spike glycoprotein

Chukwudozie OS, Gray CM, Fagbayi TA, Chukwuanukwu RC, Oyebanji VO, Bankole TT, Adewole RA, Daniel EM.

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Use of a rapid point-of-care molecular test in the triage of suspected COVID-19 cases

Ciotti M, Nicolai E, Marcuccilli F, Bernardini S.

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Genomic and healthcare dynamics of nosocomial SARS-CoV-2 transmission

Ellingford JM, George R, McDermott JH, Ahmad S, Edgerley JJ, Gokhale D, Newman WG, Ball S, Machin N, Black GC.

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Cefaclor Monohydrate-Loaded Colon-Targeted Nanoparticles for Use in COVID-19 Dependent Coinfections and Intestinal Symptoms: Formulation, Characterization, Release Kinetics, and Antimicrobial Activity

Alper Öztürk A, Namlı İ, Aygül A.

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Molecular Mechanism of the N501Y Mutation for Enhanced Binding between SARS-CoV-2's Spike Protein and Human ACE2 Receptor

Luan B, Wang H, Huynh T.

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VERSO: A comprehensive framework for the inference of robust phylogenies and the quantification of intra-host genomic diversity of viral samples

Ramazzotti D, Angaroni F, Maspero D, Gambacorti-Passerini C, Antoniotti M, Graudenzi A, Piazza R.

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Immunoinformatics and Molecular Docking Studies Predicted Potential Multiepitope-Based Peptide Vaccine and Novel Compounds against Novel SARS-CoV-2 through Virtual Screening

Waqas M, Haider A, Rehman A, Qasim M, Umar A, Sufyan M, Akram HN, Mir A, Razzaq R, Rasool D, Tahir RA, Sehgal SA.

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Structure of SARS-CoV-2 Spike Glycoprotein for Therapeutic and Preventive Target

Hong J, Jhun H, Choi YO, Taitt AS, Bae S, Lee Y, Song CS, Yeom SC, Kim S.

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Phytochemicals of Rhus spp. as Potential Inhibitors of the SARS-CoV-2 Main Protease: Molecular Docking and Drug-Likeness Study

Sherif YE, Gabr SA, Hosny NM, Alghadir AH, Alansari R.

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In silico identification of compounds from Nigella sativa seed oil as potential inhibitors of SARS-CoV-2 targets

Duru CE, Duru IA, Adegboyega AE.

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ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU.

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Genomic investigation of the coronavirus disease-2019 outbreak in the Republic of Korea

Kim JM, Park SY, Lee D, Kim JS, Park Y, Gwack J, Kim MY, Song DH, Jeong ST, Chung YS, Yoo CK, Lee HY, Han MG.

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Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins

Lun CM, Waheed AA, Majadly A, Powell N, Freed EO.

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Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays

Yu J, Li Z, He X, Gebre MS, Bondzie EA, Wan H, Jacob-Dolan C, Martinez DR, Nkolola JP, Baric RS, Barouch DH.

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Structural impact on SARS-CoV-2 spike protein by D614G substitution

Zhang J, Cai Y, Xiao T, Lu J, Peng H, Sterling SM, Walsh RM Jr, Rits-Volloch S, Zhu H, Woosley AN, Yang W, Sliz P, Chen B.

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Whole genome analysis of more than 10 000 SARS-CoV-2 virus unveils global genetic diversity and target region of NSP6

Saha I, Ghosh N, Pradhan A, Sharma N, Maity D, Mitra K.

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Neutralising antibody escape of SARS-CoV-2 spike protein: Risk assessment for antibody-based Covid-19 therapeutics and vaccines

Focosi D, Maggi F.

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Transmission of SARS-CoV-2 in northern Ghana: insights from whole-genome sequencing

Sylverken AA, El-Duah P, Owusu M, Schneider J, Yeboah R, Ayisi-Boateng NK, Gorman R, Adu E, Kwarteng A, Frimpong M, Binger T, Aryeetey S, Asamoah JA, Amoako YA, Amuasi JH, Beheim-Schwarzbach J, Owusu-Dabo E, Adu-Sarkodie Y, Obiri-Danso K, Corman VM, Drosten C, Phillips R.

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COVID-19 patient transcriptomic and genomic profiling reveals comorbidity interactions with psychiatric disorders

Moni MA, Lin PI, Quinn JMW, Eapen V.

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Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data

Parker MD, Lindsey BB, Leary S, Gaudieri S, Chopra A, Wyles M, Angyal A, Green LR, Parsons P, Tucker RM, Brown R, Groves D, Johnson K, Carrilero L, Heffer J, Partridge DG, Evans C, Raza M, Keeley AJ, Smith N, Filipe ADS, Shepherd JG, Davis C, Bennett S, Sreenu VB, Kohl A, Aranday-Cortes E, Tong L, Nichols J, Thomson EC; The COVID-19 Genomics UK (COG-UK) Consortium,, Wang D, Mallal S, de Silva TI.

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Evolutionary and genomic analysis of four SARS-CoV-2 isolates circulating in March 2020 in Sri Lanka; Additional evidence on multiple introductions and further transmission

Satharasinghe DA, Parakatawella PMSDK, Premarathne JMKJK, Jayasooriya LJPAP, Prathapasinghe GA, Yeap SK.

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SARS-CoV-2 vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals low levels of viral backbone gene transcription alongside very high levels of SARS-CoV-2 S glycoprotein gene transcription

Almuqrin A, Davidson AD, Williamson MK, Lewis PA, Heesom KJ, Morris S, Gilbert SC, Matthews DA.

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Involving people affected by a rare condition in shaping future genomic research

Nunn JS, Gwynne K, Gray S, Lacaze P.

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Novel perspectives for SARS-CoV-2 genome browsing

Gültekin V, Allmer J.

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SARS-CoV-2: Insight in genome structure, pathogenesis and viral receptor binding analysis - An updated review

Bhat EA, Khan J, Sajjad N, Ali A, Aldakeel FM, Mateen A, Alqahtani MS, Syed R.

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Deep learning model for virtual screening of novel 3C-like protease enzyme inhibitors against SARS coronavirus diseases

Kumari M, Subbarao N.

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Comparative evaluation of SARS-CoV-2 IgG assays against nucleocapsid and spike antigens

Rezaei M, Sadeghi M, Korourian A, Tabarsi P, Porabdollah M, Askari E, Mortaz E, Mahmoudi S, Marjani M.

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[BCG, muramylpeptides, trained immunity (part II): a low molecular weight alternative to multicomponent bacterial immunostimulants for prevention of respiratory infections during a pandemic]

Kalyuzhin OV, Andronova TM, Karaulov AV.

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Case-Control Study of Individuals with Discrepant Nucleocapsid and Spike Protein SARS-CoV-2 IgG Results

Wang H, Wiredja D, Yang L, Bulterys PL, Costales C, Röltgen K, Manalac J, Yee J, Zehnder J, Shi RZ, Boyd SD, Pinsky BA.

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Chemical and Biochemical Aspects of Molecular Hydrogen in Treating Kawasaki Disease and COVID-19

Chen KD, Lin WC, Kuo HC.

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Discovering Potential RNA Dependent RNA Polymerase Inhibitors as Prospective Drugs Against COVID-19: An in silico Approach

Saha S, Nandi R, Vishwakarma P, Prakash A, Kumar D.

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In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19

López-Cortés A, Guevara-Ramírez P, Kyriakidis NC, Barba-Ostria C, León Cáceres Á, Guerrero S, Ortiz-Prado E, Munteanu CR, Tejera E, Cevallos-Robalino D, Gómez-Jaramillo AM, Simbaña-Rivera K, Granizo-Martínez A, Pérez-M G, Moreno S, García-Cárdenas JM, Zambrano AK, Pérez-Castillo Y, Cabrera-Andrade A, Puig San Andrés L, Proaño-Castro C, Bautista J, Quevedo A, Varela N, Quiñones LA, Paz-Y-Miño C.

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Inhibition of interferon-stimulated gene 15 and lysine 48-linked ubiquitin binding to the SARS-CoV-2 papain-like protease by small molecules: In silico studies

Pitsillou E, Liang J, Hung A, Karagiannis TC.

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Biological perspective of thiazolide derivatives against Mpro and MTase of SARS-CoV-2: Molecular docking, DFT and MD simulation investigations

Rasool N, Yasmin F, Sahai S, Hussain W, Inam H, Arshad A.

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Clinical and public health utility of Mycobacterium tuberculosis whole genome sequencing

Kizny Gordon A, Marais B, Walker TM, Sintchenko V.

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A rational design of a multi-epitope vaccine against SARS-CoV-2 which accounts for the glycan shield of the spike glycoprotein

Martin WR, Cheng F.

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Black tea bioactives as inhibitors of multiple targets of SARS-CoV-2 (3CLpro, PLpro and RdRp): a virtual screening and molecular dynamic simulation study

Gogoi M, Borkotoky M, Borchetia S, Chowdhury P, Mahanta S, Barooah AK.

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In silico drug designing for COVID-19: an approach of high-throughput virtual screening, molecular, and essential dynamics simulations

Kumar R, Kumar R, Tanwar P.

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Development of a SARS-CoV-2 nucleocapsid specific monoclonal antibody

Terry JS, Anderson LB, Scherman MS, McAlister CE, Perera R, Schountz T, Geiss BJ.

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Chemodynamic features of nanoparticles: Application to understanding the dynamic life cycle of SARS-CoV-2 in aerosols and aqueous biointerfacial zones

Duval JFL, van Leeuwen HP, Norde W, Town RM.

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The SARS-CoV-2 subgenome landscape and its novel regulatory features

Wang D, Jiang A, Feng J, Li G, Guo D, Sajid M, Wu K, Zhang Q, Ponty Y, Will S, Liu F, Yu X, Li S, Liu Q, Yang XL, Guo M, Li X, Chen M, Shi ZL, Lan K, Chen Y, Zhou Y.

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The effect of spike mutations on SARS-CoV-2 neutralization

Rees-Spear C, Muir L, Griffith SA, Heaney J, Aldon Y, Snitselaar JL, Thomas P, Graham C, Seow J, Lee N, Rosa A, Roustan C, Houlihan CF, Sanders RW, Gupta RK, Cherepanov P, Stauss HJ, Nastouli E; SAFER Investigators, Doores KJ, van Gils MJ, McCoy LE.

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Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus

Yan L, Song Y, Xia K, He P, Zhang F, Chen S, Pouliot R, Weiss DJ, Tandon R, Bates JT, Ederer DR, Mitra D, Sharma P, Davis A, Linhardt RJ.

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The influence of IFITM3 polymorphisms on susceptibility to SARS-CoV-2 infection and severity of COVID-19

Schönfelder K, Breuckmann K, Elsner C, Dittmer U, Fistera D, Herbstreit F, Risse J, Schmidt K, Sutharsan S, Taube C, Jöckel KH, Siffert W, Kribben A, Möhlendick B.

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Head-to-head comparison of two rapid high-throughput automated electrochemiluminescence immunoassays targeting total antibodies to the SARS-CoV-2 nucleoprotein and spike protein receptor binding domain

Poljak M, Oštrbenk Valenčak A, Štamol T, Seme K.

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Pattern of genomic variation in SARS-CoV-2 (COVID-19) suggests restricted nonrandom changes: Analysis using Shewhart control charts

Mandal S, Roychowdhury T, Bhattacharya A.

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Synthetic Homogeneous Glycoforms of the SARS-CoV-2 Spike Receptor-Binding Domain Reveals Different Binding Profiles of Monoclonal Antibodies

Wang P, Ye F, Zhao J, Xu P, Liu X, Yu J, Shangguan W, Liu J, Luo X, Li C, Ying T, Wang J, Yu B.

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Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

Zhang S, Qiao S, Yu J, Zeng J, Shan S, Tian L, Lan J, Zhang L, Wang X.

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Coding-Complete Genome Sequences and Mutation Profiles of Nine SARS-CoV-2 Strains Detected from COVID-19 Patients in Bangladesh

Adnan N, Khondoker MU, Rahman MS, Ahmed MF, Sharmin S, Sharif N, Azmuda N, Akter S, Nahar S, Mou TJ, Marzan M, Liza SM, Jahan N, Ali T, Khandker SS, Jamiruddin M, Chaity MA, Caller LG, Haq MA, Jamiruddin MR.

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Coding-Complete Genome Sequence and Phylogenetic Relatedness of a SARS-CoV-2 Strain Detected in March 2020 in Cameroon

Njouom R, Sadeuh-Mba SA, Tchatchueng J, Diagne MM, Dia N, Tagnouokam PAN, Boum Y, Hamadou A, Esso L, Faye O, Tejiokem MC, Okomo MC, Etoundi A, Carniel E, Eyangoh S.

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Towards a sensitive and accurate interpretation of molecular testing for SARS-CoV-2: a rapid review of 264 studies

Stanoeva KR, van der Eijk AA, Meijer A, Kortbeek LM, Koopmans MPG, Reusken CBEM.

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Tracking SARS-CoV-2 lineage B.1.1.7 dissemination: insights from nationwide spike gene target failure (SGTF) and spike gene late detection (SGTL) data, Portugal, week 49 2020 to week 3 2021

Borges V, Sousa C, Menezes L, Gonçalves AM, Picão M, Almeida JP, Vieita M, Santos R, Silva AR, Costa M, Carneiro L, Casaca P, Pinto-Leite P, Peralta-Santos A, Isidro J, Duarte S, Vieira L, Guiomar R, Silva S, Nunes B, Gomes JP.

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Potential inhibitors of angiotensin converting enzyme 2 receptor of COVID-19 by Corchorus olitorius Linn using docking, molecular dynamics, conceptual DFT investigation and pharmacophore mapping

Mesli F, Ghalem M, Daoud I, Ghalem S.

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Clinical and molecular aspects of veterinary coronaviruses

Colina SE, Serena MS, Echeverría MG, Metz GE.

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Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2

Ghorbani M, Brooks BR, Klauda JB.

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SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines

Shen X, Tang H, McDanal C, Wagh K, Fischer W, Theiler J, Yoon H, Li D, Haynes BF, Sanders KO, Gnanakaran S, Hengartner N, Pajon R, Smith G, Glenn GM, Korber B, Montefiori DC.

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Immunoinformatic analysis of structural and epitope variations in the spike and Orf8 proteins of SARS-CoV-2/B.1.1.7

Hussain M, Shabbir S, Amanullah A, Raza F, Imdad MJ, Zahid S.

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Impact of the COVID-19 Vaccine on Asymptomatic Infection Among Patients Undergoing Pre-Procedural COVID-19 Molecular Screening

Tande AJ, Pollock BD, Shah ND, Farrugia G, Virk A, Swift M, Breeher L, Binnicker M, Berbari EF.

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The protease inhibitor lopinavir, boosted with ritonavir, as treatment for COVID-19: a rapid review

Dorward J, Gbinigie O, Cai T, Roberts NW, Garrett N, Hayward G, Butler CC.

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Role of ACE2 genetic polymorphisms in susceptibility to SARS-CoV-2 among highly exposed but non infected healthcare workers

Martínez-Sanz J, Jiménez D, Martínez-Campelo L, Cruz R, Vizcarra P, Sánchez-Conde M, Ron R, Rodríguez M, Herrera S, Moreno S, López-Huertas MR, Serrano-Villar S.

Abstract:

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Estimated half-life of SARS-CoV-2 anti-spike antibodies more than double the half-life of anti-nucleocapsid antibodies in healthcare workers

Van Elslande J, Gruwier L, Godderis L, Vermeersch P.

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Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients

Tomić S, Đokić J, Stevanović D, Ilić N, Gruden-Movsesijan A, Dinić M, Radojević D, Bekić M, Mitrović N, Tomašević R, Mikić D, Stojanović D, Čolić M.

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Blockade of SARS-CoV-2 spike protein-mediated cell-cell fusion using COVID-19 convalescent plasma

Wang L, Zhao J, Nguyen LNT, Adkins JL, Schank M, Khanal S, Nguyen LN, Dang X, Cao D, Thakuri BKC, Lu Z, Zhang J, Zhang Y, Wu XY, El Gazzar M, Ning S, Moorman JP, Yao ZQ.

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SARS-CoV-2 rapidly adapts in aged BALB/c mice and induces typical pneumonia

Zhang Y, Huang K, Wang T, Deng F, Gong W, Hui X, Zhao Y, He X, Li C, Zhang Q, Chen X, Lv C, Lin X, Yang Y, Sun X, Shi Z, Chen H, Zou Z, Jin M.

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The pharmacological mechanism of Huashi Baidu Formula for the treatment of COVID-19 by combined network pharmacology and molecular docking

Cai Y, Zeng M, Chen YZ.

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Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution

Ong EZ, Kalimuddin S, Chia WC, Ooi SH, Koh CW, Tan HC, Zhang SL, Low JG, Ooi EE, Chan KR.

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Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein

Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, Doolabh D, Pillay S, San EJ, Msomi N, Mlisana K, von Gottberg A, Walaza S, Allam M, Ismail A, Mohale T, Glass AJ, Engelbrecht S, Van Zyl G, Preiser W, Petruccione F, Sigal A, Hardie D, Marais G, Hsiao M, Korsman S, Davies MA, Tyers L, Mudau I, York D, Maslo C, Goedhals D, Abrahams S, Laguda-Akingba O, Alisoltani-Dehkordi A, Godzik A, Wibmer CK, Sewell BT, Lourenço J, Alcantara LCJ, Kosakovsky Pond SL, Weaver S, Martin D,

Abstract:

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A straightforward molecular strategy to retrospectively investigate the spread of SARS-CoV-2 VOC202012/01 B.1.1.7 variant

Ibba G, Sau R, Angioj F, Abbondio M, Rubino S, Uzzau S.

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Molecular mechanisms of Na,K-ATPase dysregulation driving alveolar epithelial barrier failure in severe COVID-19

Kryvenko V, Vadász I.

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Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane

Choi YK, Cao Y, Frank M, Woo H, Park SJ, Yeom MS, Croll TI, Seok C, Im W.

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Novel Negative Sense Genes in the RNA Genome of Coronaviruses

Zhirnov OP, Poyarkov SV.

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Estimation of secondary household attack rates for emergent SARS-CoV-2 variants detected by genomic surveillance at a community-based testing site in San Francisco

Peng J, Mann SA, Mitchell AM, Liu J, Laurie MT, Sunshine S, Pilarowski G, Ayscue P, Kistler A, Vanaerschot M, Li LM, McGeever A, Chow ED, Team I, Marquez C, Nakamura R, Rubio L, Chamie G, Jones D, Jacobo J, Rojas S, Rojas S, Tulier-Laiwa V, Black D, Martinez J, Naso J, Schwab J, Petersen M, Havlir D, DeRisi J.

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SARS-CoV-2 Total and Subgenomic RNA Viral Load in Hospitalized Patients

Dimcheff DE, Valesano AL, Rumfelt KE, Fitzsimmons WJ, Blair C, Mirabelli C, Petrie JG, Martin ET, Bhambhani C, Tewari M, Lauring AS.

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Donor Anti-Spike Immunity is Related to Recipient Recovery and Can Predict the Efficacy of Convalescent Plasma Units

Janaka SK, Hartman W, Mou H, Farzan M, Stramer SL, Goodhue E, Weiss J, Evans D, Connor JP.

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Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants

Xu J, Xu K, Jung S, Conte A, Lieberman J, Muecksch F, Cetrulo Lorenzi JC, Park S, Wang Z, Tessarollo L, Bylund T, Chuang GY, Olia AS, Stephens T, Teng IT, Tsybovsky Y, Zhou T, Hatziioannou T, Bieniasz PD, Nussenzweig MC, Kwong PD, Casellas R.

Abstract:

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Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

Francica JR, Flynn BJ, Foulds KE, Noe AT, Werner AP, Moore IN, Gagne M, Johnston TS, Tucker C, Davis RL, Flach B, O'Connell S, Andrew SF, Lamb E, Flebbe DR, Nurmukhambetova ST, Donaldson MM, Todd JM, Zhu AL, Atyeo C, Fischinger S, Gorman MJ, Shin S, Edara VV, Floyd K, Lai L, Tylor A, McCarthy E, Lecouturier V, Ruiz S, Berry C, Tibbitts T, Andersen H, Cook A, Dodson A, Pessaint L, Ry AV, Koutsoukos M, Gutzeit C, Teng IT, Zhou T, Li D, Haynes BF, Kwong PD, McDermott A, Lewis MG, Fu TM, Chicz R, va

Abstract:

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Neutralizing IFNL3 Autoantibodies in Severe COVID-19 Identified Using Molecular Indexing of Proteins by Self-Assembly

Credle JJ, Gunn J, Sangkhapreecha P, Monaco DR, Zheng XA, Tsai HJ, Wilbon A, Morgenlander WR, Dong Y, Jayaraman S, Tosi L, Parekkadan B, Baer AN, Roederer M, Bloch EM, Tobian AAR, Zyskind I, Silverberg JI, Rosenberg AZ, Cox AL, Lloyd T, Mammen AL, Larman HB.

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Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Native Top-Down Mass Spectrometry

Roberts DS, Mann MW, Melby JA, Larson EJ, Zhu Y, Brasier AR, Jin S, Ge Y.

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Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

Dalvie NC, Rodriguez-Aponte SA, Hartwell BL, Tostanoski LH, Biedermann AM, Crowell LE, Kaur K, Kumru O, Carter L, Yu J, Chang A, McMahan K, Courant T, Lebas C, Lemnios AA, Rodrigues KA, Silva M, Johnston RS, Naranjo CA, Tracey MK, Brady JR, Whittaker CA, Yun D, Kar S, Porto M, Lok M, Andersen H, Lewis MG, Love KR, Camp DL, Silverman JM, Kleanthous H, Joshi SB, Volkin DB, Dubois PM, Collin N, King NP, Barouch DH, Irvine DJ, Love JC.

Abstract:

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Urine proteome of COVID-19 patients

Li Y, Wang Y, Liu H, Sun W, Ding B, Zhao Y, Chen P, Zhu L, Li Z, Li N, Chang L, Wang H, Bai C, Xu P.

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In silico analysis of altered expression of long non-coding RNA in SARS-CoV-2 infected cells and their possible regulation by STAT1, STAT3 and interferon regulatory factors

Laha S, Saha C, Dutta S, Basu M, Chatterjee R, Ghosh S, Bhattacharyya NP.

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The study of antiviral drugs targeting SARS-CoV-2 nucleocapsid and spike proteins through large-scale compound repurposing

Hu X, Zhou Z, Li F, Xiao Y, Wang Z, Xu J, Dong F, Zheng H, Yu R.

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One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection

Liu R, Americo JL, Cotter CA, Earl PL, Erez N, Peng C, Moss B.

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Exploring Spike Protein as Potential Target of Novel Coronavirus and to Inhibit the Viability utilizing Natural Agents

Nandi S, Roy H, Gummadi A, Saxena A.

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Transcriptomic profiling and genomic mutational analysis of Human coronavirus (HCoV)-229E -infected human cells

Friedman N, Jacob-Hirsch J, Drori Y, Eran E, Kol N, Nayshool O, Mendelson E, Rechavi G, Mandelboim M.

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Short sequence motif dynamics in the SARS-CoV-2 genome suggest a role for cytosine deamination in CpG reduction

Sadykov M, Mourier T, Guan Q, Pain A.

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The Effects of "Dry Swab" Incubation on SARS-CoV-2 Molecular Testing

Parikh BA, Wallace MA, McCune BT, Burnham CD, Anderson NW.

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Microfluidic Magneto Immunosensor for Rapid, High Sensitivity Measurements of SARS-CoV-2 Nucleocapsid Protein in Serum

Li J, Lillehoj PB.

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Evaluation of molecular interaction, physicochemical parameters and conserved pattern of SARS-CoV-2 Spike RBD and hACE2: in silico and molecular dynamics approach

Chakraborty C, Sharma AR, Mallick B, Bhattacharya M, Sharma G, Lee SS.

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A Biochemical Perspective of the Nonstructural Proteins (NSPs) and the Spike Protein of SARS CoV-2

Yoshimoto FK.

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A Rapid, High-Sensitivity SARS-CoV-2 Nucleocapsid Immunoassay to Aid Diagnosis of Acute COVID-19 at the Point of Care: A Clinical Performance Study

Drain PK, Ampajwala M, Chappel C, Gvozden AB, Hoppers M, Wang M, Rosen R, Young S, Zissman E, Montano M.

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Coagulopathy profiles and their correlation with molecular viral burden in patients with COVID-19

Park HS, Shin KS, Son BR.

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Assessment of SARS-CoV-2 infectivity of upper respiratory specimens from COVID-19 patients by virus isolation using VeroE6/TMPRSS2 cells

Yamada S, Fukushi S, Kinoshita H, Ohnishi M, Suzuki T, Fujimoto T, Saijo M, Maeda K; Virus Diagnosis Group (NIID Toyama).

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Crystallographic molecular replacement using an in silico-generated search model of SARS-CoV-2 ORF8

Flower TG, Hurley JH.

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4-acetamido-3-nitrobenzoic acid - structural, quantum chemical studies, ADMET and molecular docking studies of SARS-CoV2

Gurumallappa, Arun Renganathan RR, Hema MK, Karthik CS, Rani S, Nethaji M, Jayanth HS, Mallu P, Lokanath NK, Ravishankar Rai V.

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Post-mortem molecular investigations of SARS-CoV-2 in an unexpected death of a recent kidney transplant recipient

Simms EL, Chung H, Oberding L, Muruve D, McDonald B, Bromley A, Pillai DR, Chun J.

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Innate immune evasion mediated by picornaviral 3C protease: Possible lessons for coronaviral 3C-like protease?

Ng CS, Stobart CC, Luo H.

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A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico investigation

Rakib A, Nain Z, Sami SA, Mahmud S, Islam A, Ahmed S, Siddiqui ABF, Babu SMOF, Hossain P, Shahriar A, Nainu F, Emran TB, Simal-Gandara J.

Abstract:

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Characterizing genomic variants and mutations in SARS-CoV-2 proteins from Indian isolates

Das JK, Sengupta A, Choudhury PP, Roy S.

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Evaluation of drug repositioning by molecular docking of pharmaceutical resources available in the Brazilian healthcare system against SARS-CoV-2

Grahl MVC, Alcará AM, Perin APA, Moro CF, Pinto ÉSM, Feltes BC, Ghilardi IM, Rodrigues FVF, Dorn M, da Costa JC, Norberto de Souza O, Ligabue-Braun R.

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Ultra-large-scale ab initio quantum chemical computation of bio-molecular systems: the case of Spike protein of SARS-CoV-2 virus

Ching WY, Adhikari P, Jawad B, Podgornik R.

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Identification of high affinity and low molecular alternatives of boceprevir against SARS-CoV-2 main protease: a virtual screening approach

Borkotoky S, Banerjee M, Prakash Modi G, Kumar Dubey V.

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SARS-CoV-2 molecular testing in Greek hospital pediatric departments: A nationwide study

Michos A, Savvidou P, Syridou L, Eleftheriou E, Iosifidis E, Grivea I, Spoulou V, Galanakis E, Syrogiannopoulos G, Tsolia M, Roilides E, Papaevangelou V.

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Effects of statins on myocarditis: A review of underlying molecular mechanisms

Parsamanesh N, Karami-Zarandi M, Banach M, Penson PE, Sahebkar A.

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Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity

Thomson EC, Rosen LE, Shepherd JG, Spreafico R, da Silva Filipe A, Wojcechowskyj JA, Davis C, Piccoli L, Pascall DJ, Dillen J, Lytras S, Czudnochowski N, Shah R, Meury M, Jesudason N, De Marco A, Li K, Bassi J, O'Toole A, Pinto D, Colquhoun RM, Culap K, Jackson B, Zatta F, Rambaut A, Jaconi S, Sreenu VB, Nix J, Zhang I, Jarrett RF, Glass WG, Beltramello M, Nomikou K, Pizzuto M, Tong L, Cameroni E, Croll TI, Johnson N, Di Iulio J, Wickenhagen A, Ceschi A, Harbison AM, Mair D, Ferrari P, Smollett

Abstract:

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Shedding Light on the Inhibitory Mechanisms of SARS-CoV-1/CoV-2 Spike Proteins by ACE2-Designed Peptides

Freitas FC, Ferreira PHB, Favaro DC, Oliveira RJ.

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Early pandemic molecular diversity of SARS-CoV-2 in children

Moustafa AM, Otto W, Gai X, Pandey U, Ryutov A, Bootwalla M, Maglinte DT, Shen L, Ruble D, Ostrow D, Gerber JS, Bard JD, Harris RM, Planet PJ.

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HLA binding of self-peptides is biased towards proteins with specific molecular functions

Karnaukhov V, Paes W, Woodhouse IB, Partridge T, Nicastri A, Brackenridge S, Scherbinin D, Chudakov DM, Zvyagin IV, Ternette N, Koohy H, Borrow P, Shugay M.

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A glycan gate controls opening of the SARS-CoV-2 spike protein

Sztain T, Ahn SH, Bogetti AT, Casalino L, Goldsmith JA, McCool RS, Kearns FL, McCammon JA, McLellan JS, Chong LT, Amaro RE.

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Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

Turner HL, Andrabi R, Cottrell CA, Richey ST, Song G, Callaghan S, Anzanello F, Moyer TJ, Abraham W, Melo M, Silva M, Scaringi N, Rakasz EG, Sattentau Q, Irvine DJ, Burton DR, Ward AB.

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Rotavirus as an Expression Platform of the SARS-CoV-2 Spike Protein

Philip AA, Patton JT.

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Decreased neutralization of SARS-CoV-2 global variants by therapeutic anti-spike protein monoclonal antibodies

Tada T, Dcosta BM, Zhou H, Vaill A, Kazmierski W, Landau NR.

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The Host Interactome of Spike Expands the Tropism of SARS-CoV-2

Bamberger C, Pankow S, Martínez-Bartolomé S, Diedrich J, Park R, Yates J.

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Supervised machine learning approach to molecular dynamics forecast of SARS-CoV-2 spike glycoproteins at varying temperatures

Liang D, Song M, Niu Z, Zhang P, Rafailovich M, Deng Y.

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In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

Phan IQ, Subramanian S, Kim D, Murphy M, Pettie D, Carter L, Anishchenko I, Barrett LK, Craig J, Tillery L, Shek R, Harrington WE, Koelle DM, Wald A, Veesler D, King N, Boonyaratanakornkit J, Isoherranen N, Greninger AL, Jerome KR, Chu H, Staker B, Stewart L, Myler PJ, Van Voorhis WC.

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Serine 477 plays a crucial role in the interaction of the SARS-CoV-2 spike protein with the human receptor ACE2

Singh A, Steinkellner G, Köchl K, Gruber K, Gruber CC.

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Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19

Yao Y, Ye F, Li K, Xu P, Tan W, Feng Q, Rao S.

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Identification and functional analysis of the SARS-COV-2 nucleocapsid protein

Gao T, Gao Y, Liu X, Nie Z, Sun H, Lin K, Peng H, Wang S.

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Investigation of the inhibitory activity of some dietary bioactive flavonoids against SARS-CoV-2 using molecular dynamics simulations and MM-PBSA calculations

Varughese JK, Joseph Libin KL, Sindhu KS, Rosily AV, Abi TG.

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Structural stability predictions and molecular dynamics simulations of RBD and HR1 mutations associated with SARS-CoV-2 spike glycoprotein

Ahamad S, Hema K, Gupta D.

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Synthesis of silver nanoparticles using gum Arabic: Evaluation of its inhibitory action on Streptococcus mutans causing dental caries and endocarditis

Al-Ansari MM, Al-Dahmash ND, Ranjitsingh AJA.

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Protease targeted COVID-19 drug discovery: What we have learned from the past SARS-CoV inhibitors?

Amin SA, Banerjee S, Gayen S, Jha T.

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Saliva for molecular detection of SARS-CoV-2 in school-aged children

Al Suwaidi H, Senok A, Varghese R, Deesi Z, Khansaheb H, Pokasirakath S, Chacko B, Abufara I, Loney T, Alsheikh-Ali A.

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Characterizing SARS-CoV-2 genome diversity circulating in South American countries: signatures of potentially emergent lineages?

Muñoz M, Patiño LH, Ballesteros N, Paniz-Mondolfi A, Ramírez JD.

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In silico identification of available drugs targeting cell surface BiP to disrupt SARS-CoV-2 binding and replication: Drug repurposing approach

Zhang Y, Greer RA, Song Y, Praveen H, Song Y.

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In silico evaluation of isatin-based derivatives with RNA-dependent RNA polymerase of the novel coronavirus SARS-CoV-2

M RK, Gideon DA, Mariadasse R, Nirusimhan V, A SR, Edward JC, Jeyaraman J, Dhayabaran V 5th.

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High performance of a novel antigen detection test on nasopharyngeal specimens for diagnosing SARS-CoV-2 infection

Courtellemont L, Guinard J, Guillaume C, Giaché S, Rzepecki V, Seve A, Gubavu C, Baud K, Le Helloco C, Cassuto GN, Pialoux G, Hocqueloux L, Prazuck T.

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Adsorption of SARS-CoV-2 Spike Protein S1 at Oxide Surfaces Studied by High-Speed Atomic Force Microscopy

Xin Y, Grundmeier G, Keller A.

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Docking Prediction of Levodopa in the Receptor Binding Domain of Spike Protein of SARS-CoV-2

Baig AM, Khaleeq A, Syeda H, Bibi N.

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Identification of Novel MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating the EGFR-ADAM17 Axis: An In Silico Analysis

Mukhopadhyay D, AlSawaftah N, Husseini GA.

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Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalization

Morgan DC, Morris C, Mahindra A, Blair CM, Tejeda G, Herbert I, Turnbull ML, Lieber G, Willett BJ, Logan N, Smith B, Tobin AB, Bhella D, Baillie G, Jamieson AG.

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In silico Exploration of Inhibitors for SARS-CoV-2's Papain-Like Protease

Huynh T, Cornell W, Luan B.

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In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease

Yañez O, Osorio MI, Uriarte E, Areche C, Tiznado W, Pérez-Donoso JM, García-Beltrán O, González-Nilo F.

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Advanced Material Against Human (Including Covid-19) and Plant Viruses: Nanoparticles As a Feasible Strategy

Tortella GR, Rubilar O, Diez MC, Padrão J, Zille A, Pieretti JC, Seabra AB.

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Aggregation hot spots in the SARS-CoV-2 proteome may constitute potential therapeutic targets for the suppression of the viral replication and multiplication

Gour S, Yadav JK.

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Rational design of potent anti-COVID-19 main protease drugs: An extensive multi-spectrum in silico approach

Ahmad S, Waheed Y, Ismail S, Najmi MH, Ansari JK.

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Molecular modeling-guided optimization of acetylcholinesterase reactivators: A proof for reactivation of covalently inhibited targets

Wei Z, Yang J, Liu Y, Nie H, Yao L, Yang J, Guo L, Zheng Z, Ouyang Q.

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Molecular mimicry between SARS-CoV-2 and human proteins

Adiguzel Y.

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Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis

Hou Y, Ge S, Li X, Wang C, He H, He L.

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A potential interaction between the SARS-CoV-2 spike protein and nicotinic acetylcholine receptors

Oliveira ASF, Ibarra AA, Bermudez I, Casalino L, Gaieb Z, Shoemark DK, Gallagher T, Sessions RB, Amaro RE, Mulholland AJ.

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Repurposing of thalidomide and its derivatives for the treatment of SARS-coV-2 infections: Hints on molecular action

Sunderesan L, Giri S, Singh H, Chatterjee S.

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Whole-genome Sequencing of SARS-CoV-2: Using Phylogeny and Structural Modeling to Contextualize Local Viral Evolution

Nazario-Toole AE, Xia H, Gibbons TF.

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Pediatric Asthma Exacerbations during the COVID-19 Pandemic: Absence of the Typical Fall Seasonal Spike in Washington, DC

Sheehan WJ, Patel SJ, Margolis RHF, Fox ER, Shelef DQ, Kachroo N, Pillai D, Teach SJ.

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Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction

Cao W, Dong C, Kim S, Hou D, Tai W, Du L, Im W, Zhang XF.

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Array-based Dynamic Allele Specific Hybridization (Array-DASH): optimization-free microarray processing for multiple simultaneous genomic assays

Gibson SJ, Zahra N, Freeman PJ, Howard C, Lancaster O, Veal C, Fontdevila MC, Paredes R, Noguera-Julian M, Slater A, Brookes AJ.

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Exploring novel and potent cell penetrating peptides in the proteome of SARS-COV-2 using bioinformatics approaches

Kardani K, Bolhassani A.

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Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil

Nonaka CKV, Franco MM, Gräf T, de Lorenzo Barcia CA, de Ávila Mendonça RN, de Sousa KAF, Neiva LMC, Fosenca V, Mendes AVA, de Aguiar RS, Giovanetti M, de Freitas Souza BS.

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High-throughput detection of antibodies targeting the SARS-CoV-2 Spike in longitudinal convalescent plasma samples

Anand SP, Prévost J, Richard J, Perreault J, Tremblay T, Drouin M, Fournier MJ, Lewin A, Bazin R, Finzi A.

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A longitudinal study of convalescent plasma (CCP) donors and correlation of ABO group, initial neutralizing antibodies (nAb), and body mass index (BMI) with nAb and anti-nucleocapsid (NP) SARS-CoV-2 antibody kinetics: Proposals for better quality of CCP collections

Wendel S, Fontão-Wendel R, Fachini R, Candelaria G, Scuracchio P, Achkar R, Brito M, Reis LF, Camargo A, Amano M, Machado R, Araujo D, Soares C, Durigon E.

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Use of Virus-Mimicking Nanoparticles to Investigate Early Infection Events in Upper Airway 3D Models

Pennarossa G, Fazeli A, Ledda S, Gandolfi F, Brevini TAL.

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Synchrotron Radiation as a Tool for Macromolecular X-Ray Crystallography: a XXI Century Perspective

Grabowski M, Cooper DR, Brzezinski D, Macnar JM, Shabalin IG, Cymborowski M, Otwinowski Z, Minor W.

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Molecular features similarities between SARS-CoV-2, SARS, MERS and key human genes could favour the viral infections and trigger collateral effects

Maldonado LL, Bertelli AM, Kamenetzky L.

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Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission

Sapoval N, Mahmoud M, Jochum M, Liu Y, Elworth RAL, Wang Q, Albin D, Ogilvie H, Lee MD, Villapol S, Hernandez K, Maljkovic Berry I, Foox J, Beheshti A, Ternus K, Aagaard K, Posada D, Mason C, Sedlazeck FJ, Treangen TJ.

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Could combustion-generated nanoparticles induce cytotoxicity also at the extremely low doses typical of indoor environments?

Pedata P.

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In silico prediction of SARS-CoV-2 main protease and polymerase inhibitors: 3D-Pharmacophore modelling

Mosayebnia M, Hajiagha Bozorgi A, Rezaeianpour M, Kobarfard F.

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The analysis on the human protein domain targets and host-like interacting motifs for the MERS-CoV and SARS-CoV/CoV-2 infers the molecular mimicry of coronavirus

Martínez YA, Guo X, Portales-Pérez DP, Rivera G, Castañeda-Delgado JE, García-Pérez CA, Enciso-Moreno JA, Lara-Ramírez EE.

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Molecular diagnostic assays for COVID-19: an overview

Habibzadeh P, Mofatteh M, Silawi M, Ghavami S, Faghihi MA.

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Synthesis, structural, spectral, antioxidant, bioactivity and molecular docking investigations of a novel triazole derivative

Alaşalvar C, Öztürk N, Gökce H, Güder A, Menteşe E, Bektaş H.

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In silico approach: docking study of oxindole derivatives against the main protease of COVID-19 and its comparison with existing therapeutic agents

Shah VR, Bhaliya JD, Patel GM.

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Severe acute respiratory syndrome-coronavirus-2 spike (S) protein based vaccine candidates: State of the art and future prospects

Arashkia A, Jalilvand S, Mohajel N, Afchangi A, Azadmanesh K, Salehi-Vaziri M, Fazlalipour M, Pouriayevali MH, Jalali T, Mousavi Nasab SD, Roohvand F, Shoja Z; SARS CoV-2 Rapid Response Team of Pasteur Institute of Iran (PII).

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Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677

Hodcroft EB, Domman DB, Snyder DJ, Oguntuyo K, Van Diest M, Densmore KH, Schwalm KC, Femling J, Carroll JL, Scott RS, Whyte MM, Edwards MD, Hull NC, Kevil CG, Vanchiere JA, Lee B, Dinwiddie DL, Cooper VS, Kamil JP.

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Genomic surveillance of SARS-CoV-2 in the Bronx enables clinical and epidemiological inference

Fels JM, Khan S, Forster R, Skalina KA, Sirichand S, Fox AS, Bergman A, Mitchell WB, Wolgast LR, Szymczak WA, Bortz RH, Dieterle ME, Florez C, Haslwanter D, Jangra RK, Laudermilch E, Wirchnianski AS, Barnhill J, Goldman DL, Khine H, Goldstein DY, Daily JP, Chandran K, Kelly L.

Abstract:

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Transformations, Comparisons, and Analysis of Down to Up Protomer States of Variants of the SARS-CoV-2 Prefusion Spike Protein Including the UK Variant B.1.1.7

Peters MH, Bastidas O, Kokron DS, Henze CE.

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Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin

Qian Y, Lei T, Patel P, Lee C, Monaghan-Nichols P, Xin HB, Qiu J, Fu M.

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SARS-CoV-2 European resurgence foretold: interplay of introductions and persistence by leveraging genomic and mobility data

Lemey P, Ruktanonchai N, Hong S, Colizza V, Poletto C, den Broeck FV, Gill M, Ji X, Levasseur A, Sadilek A, Lai S, Tatem A, Baele G, Suchard M, Dellicour S.

Abstract:

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A genomic region associated with protection against severe COVID-19 is inherited from Neandertals

Zeberg H, Pääbo S.

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Evidence of protein binding by a nucleopeptide based on a thymine-decorated L-diaminopropanoic acid through CD and in silico studies

Roviello V, Musumeci D, Mokhir A, Roviello GN.

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Epidemiological surveillance of SARS-CoV-2 by genome quantification in wastewater applied to a city in the northeast of France: Comparison of ultrafiltration- and protein precipitation-based methods

Bertrand I, Challant J, Jeulin H, Hartard C, Mathieu L, Lopez S; Scientific Interest Group Obépine, Schvoerer E, Courtois S, Gantzer C.

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Glossary of phytoconstituents: Can these be repurposed against SARS CoV-2. A quick in silico screening of various phytoconstituents from plant Glycyrrhiza glabra with SARS CoV-2 main protease

Hejazi II, Beg MA, Imam A, Athar F, Islam A.

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Anti-Spike S1 Receptor-Binding Domain Antibodies against SARS-CoV-2 Persist Several Months after Infection Regardless of Disease Severity

Fiore BD, Paola L, Eugenio M, Gaetano B, Anna V, Antonella L, Annalisa S, Laura M.

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Repurposing drugs and identification of inhibitors of integral proteins (spike protein and main protease) of SARS-CoV-2

Shode FO, Idowu ASK, Uhomoibhi OJ, Sabiu S.

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Evidence of SARS-CoV-2 reinfection without mutations in Spike protein

Kulkarni O, Narreddy S, Zaveri L, Kalal IG, Tallapaka KB, Sowpati DT.

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Are vanadium complexes druggable against the main protease m(pro) of sars-cov-2? - a computational approach

Scior T, Abdallah HH, Fatimah Zaharah Mustafa S, Antonio Guevara-García J, Rehder D.

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Hospital laboratory experience with SARS-CoV-2 (COVID-19) molecular assay sample pooling method in New York City

Genco IS, Williams K, Pacheco J, Vele O, Duong S, Otero Espinal D.

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Genomic Evolution of Severe Acute Respiratory Syndrome Coronavirus 2 in India and Vaccine Impact

Jacob JJ, Vasudevan K, Veeraraghavan B, Iyadurai R, Gunasekaran K.

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Transmission dynamics of SARS-CoV-2 on the Diamond Princess uncovered using viral genome sequence analysis

Hoshino K, Maeshiro T, Nishida N, Sugiyama M, Fujita J, Gojobori T, Mizokami M.

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Making sense of spike D614G in SARS-CoV-2 transmission

Shi AC, Xie X.

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A comprehensive profile of genomic variations in the SARS-CoV-2 isolates from the state of Telangana, India

Gupta A, Sabarinathan R, Bala P, Donipadi V, Vashisht D, Katika MR, Kandakatla M, Mitra D, Dalal A, Bashyam MD.

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Non-canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus

Wang Y, Sharma P, Jefferson M, Zhang W, Bone B, Kipar A, Bitto D, Coombes JL, Pearson T, Man A, Zhekova A, Bao Y, Tripp RA, Carding SR, Yamauchi Y, Mayer U, Powell PP, Stewart JP, Wileman T.

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Whole proteome screening and identification of potential epitopes of SARS-CoV-2 for vaccine design-an immunoinformatic, molecular docking and molecular dynamics simulation accelerated robust strategy

Ezaj MMA, Junaid M, Akter Y, Nahrin A, Siddika A, Afrose SS, Nayeem SMA, Haque MS, Moni MA, Hosen SMZ.

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Quantitative Assays Reveal Cell Fusion at Minimal Levels of SARS-CoV-2 Spike Protein and Fusion-from-Without

Theuerkauf SA, Michels A, Riechert V, Maier TJ, Flory E, Cichutek K, Buchholz CJ.

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Structural Comparison of the SARS CoV 2 Spike Protein Relative to Other Human-Infecting Coronaviruses

Cueno ME, Imai K.

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COVID-19-Induced Pancytopenia in a Major Molecular Response CML Patient on Dasatinib: A Case Report and Review of the Literature

Singh B, Ayad S, Kaur P, Kumar V, Gupta S, Maroules M.

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Exploring the active constituents of Oroxylum indicum in intervention of novel coronavirus (COVID-19) based on molecular docking method

Shah S, Chaple D, Arora S, Yende S, Moharir K, Lohiya G.

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Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model

Gu T, Zhao S, Jin G, Song M, Zhi Y, Zhao R, Ma F, Zheng Y, Wang K, Liu H, Xin M, Han W, Li X, Dong CD, Liu K, Dong Z.

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Nasal Delivery of Hesperidin/Chitosan Nanoparticles Suppresses Cytokine Storm Syndrome in a Mouse Model of Acute Lung Injury

Jin H, Zhao Z, Lan Q, Zhou H, Mai Z, Wang Y, Ding X, Zhang W, Pi J, Evans CE, Liu X.

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Computational search for drug repurposing to identify potential inhibitors against SARS-COV-2 using Molecular Docking, QTAIM and IQA methods in viral Spike protein - Human ACE2 interface

Faria SHDM, Teleschi JG.

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Anti-HIV-drug and phyto-flavonoid combination against SARS-CoV-2: a molecular docking-simulation base assessment

Swain SS, Singh SR, Sahoo A, Hussain T, Pati S.

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In silico identification and validation of natural antiviral compounds as potential inhibitors of SARS-CoV-2 methyltransferase

Chandra A, Chaudhary M, Qamar I, Singh N, Nain V.

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Molecular docking, binding mode analysis, molecular dynamics, and prediction of ADMET/toxicity properties of selective potential antiviral agents against SARS-CoV-2 main protease: an effort toward drug repurposing to combat COVID-19

Rai H, Barik A, Singh YP, Suresh A, Singh L, Singh G, Nayak UY, Dubey VK, Modi G.

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Swab-Free Transport as an Optimized Preanalytical Workflow for SARS-CoV-2 Molecular Testing

Stevenson LG, deFilippi CR.

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Simpler and faster Covid-19 testing: Strategies to streamline SARS-CoV-2 molecular assays

Panpradist N, Wang Q, Ruth PS, Kotnik JH, Oreskovic AK, Miller A, Stewart SWA, Vrana J, Han PD, Beck IA, Starita LM, Frenkel LM, Lutz BR.

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Expression, purification and immunological characterization of recombinant nucleocapsid protein fragment from SARS-CoV-2

Djukic T, Mladenovic M, Stanic-Vucinic D, Radosavljevic J, Smiljanic K, Sabljic L, Devic M, Cujic D, Vasovic T, Simovic A, Radomirovic M, Cirkovic Velickovic T.

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Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies

Dobaño C, Santano R, Jiménez A, Vidal M, Chi J, Melero NR, Popovic M, López-Aladid R, Fernández-Barat L, Tortajada M, Carmona-Torre F, Reina G, Torres A, Mayor A, Carolis C, García-Basteiro AL, Aguilar R, Moncunill G, Izquierdo L.

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COVID-19 as a worldwide selective event and bitter taste receptor polymorphisms: An ecological correlational study

Parsa S, Mogharab V, Ebrahimi M, Ahmadi SR, Shahi B, Mehramiz NJ, Foroughian M, Zarenezhad M, Kalani N, Abdi MH, Javdani F, Keshavarz P, Hatami N.

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Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins

Zhang Y, Zhao W, Mao Y, Chen Y, Wang S, Zhong Y, Su T, Gong M, Du D, Lu X, Cheng J, Yang H.

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Single nucleotide polymorphisms in key aging pathways, and phenotypic markers of frailty are associated with increased odds of hospital admission with Covid-19

Scutt DG, Overall DA.

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Graph, pseudoknot, and SARS-CoV-2 genomic RNA: A biophysical synthesis

Chen SJ.

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Three Salvianolic acids inhibit 2019-nCoV spike pseudovirus viropexis by binding to both its RBD and receptor ACE2

Hu S, Wang J, Zhang Y, Bai H, Wang C, Wang N, He L.

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SARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon

Botelho-Souza LF, Nogueira-Lima FS, Roca TP, Naveca FG, de Oliveria Dos Santos A, Maia ACS, da Silva CC, de Melo Mendonça ALF, Lugtenburg CAB, Azzi CFG, Fontes JLF, Cavalcante S, de Cássia Pontello Rampazzo R, Santos CHN, Di Sabatino Guimarães AP, Máximo FR, Villalobos-Salcedo JM, Vieira DS.

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The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2

Benton DJ, Wrobel AG, Roustan C, Borg A, Xu P, Martin SR, Rosenthal PB, Skehel JJ, Gamblin SJ.

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Field-Template, QSAR, Ensemble Molecular Docking, and 3D-RISM Solvation Studies Expose Potential of FDA-Approved Marine Drugs as SARS-CoVID-2 Main Protease Inhibitors

Kalhotra P, Chittepu VCSR, Osorio-Revilla G, Gallardo-Velazquez T.

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Serological Test to Determine Exposure to SARS-CoV-2: ELISA Based on the Receptor-Binding Domain of the Spike Protein (S-RBD(N318-V510)) Expressed in Escherichia coli

Márquez-Ipiña AR, González-González E, Rodríguez-Sánchez IP, Lara-Mayorga IM, Mejía-Manzano LA, Sánchez-Salazar MG, González-Valdez JG, Ortiz-López R, Rojas-Martínez A, Trujillo-de Santiago G, Alvarez MM.

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Molecular Insights into the Thrombotic and Microvascular Injury in Placental Endothelium of Women with Mild or Severe COVID-19

Flores-Pliego A, Miranda J, Vega-Torreblanca S, Valdespino-Vázquez Y, Helguera-Repetto C, Espejel-Nuñez A, Borboa-Olivares H, Espino Y Sosa S, Mateu-Rogell P, León-Juárez M, Ramírez-Santes V, Cardona-Pérez A, Villegas-Mota I, Torres-Torres J, Juárez-Reyes Á, Rizo-Pica T, González RO, González-Mariscal L, Estrada-Gutierrez G.

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Age-dependent effects of the recombinant spike protein/SARS-CoV-2 on the M-CSF- and IL-34-differentiated macrophages in vitro

Duarte C, Akkaoui J, Ho A, Garcia C, Yamada C, Movila A.

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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 Spike for viral entry

Azad T, Singaravelu R, Taha Z, Jamieson TR, Boulton S, Crupi MJF, Martin NT, Brown EEF, Poutou J, Ghahremani M, Pelin A, Nouri K, Rezaei R, Marshall CB, Enomoto M, Arulanandam R, Alluqmani N, Samson R, Gingras AC, Cameron DW, Greer PA, Ilkow CS, Diallo JS, Bell JC.

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Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

Brouwer PJM, Brinkkemper M, Maisonnasse P, Dereuddre-Bosquet N, Grobben M, Claireaux M, de Gast M, Marlin R, Chesnais V, Diry S, Allen JD, Watanabe Y, Giezen JM, Kerster G, Turner HL, van der Straten K, van der Linden CA, Aldon Y, Naninck T, Bontjer I, Burger JA, Poniman M, Mykytyn AZ, Okba NMA, Schermer EE, van Breemen MJ, Ravichandran R, Caniels TG, van Schooten J, Kahlaoui N, Contreras V, Lemaître J, Chapon C, Fang RHT, Villaudy J, Sliepen K, van der Velden YU, Haagmans BL, de Bree GJ, Ginou

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Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection

Lodge S, Nitschke P, Kimhofer T, Wist J, Bong SH, Loo RL, Masuda R, Begum S, Richards T, Lindon JC, Bermel W, Reinsperger T, Schaefer H, Spraul M, Holmes E, Nicholson JK.

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COMPARISON OF MOLECULAR AND SEROLOGICAL TESTS FOR SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) IN POST-EXPOSURE EMPLOYEES OF THE NEPHROLOGY DEPARTMENT

Kwiatkowska M, Chomicka I, Malyszko J.

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Phylogenetic pattern of SARS-CoV-2 from COVID-19 patients from Bosnia and Herzegovina: lessons learned to optimize future molecular and epidemiological approaches

Goletic T, Konjhodzic R, Fejzic N, Goletic S, Eterovic T, Softic A, Kustura A, Salihefendic L, Ostojic M, Travar M, Mrdjen V, Tihic N, Jazic S, Musa S, Marjanovic D, Hukic M.

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Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19

Gangadevi S, Badavath VN, Thakur A, Yin N, De Jonghe S, Acevedo O, Jochmans D, Leyssen P, Wang K, Neyts J, Yujie T, Blum G.

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Molecular exploration of combinational therapy of orlistat with metformin prevents the COVID-19 consequences in obese diabetic patients

Singh Y, Gupta G, Anand K, Kumar Jha N, Thangavelu L, Kumar Chellappan D, Dua K.

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Severe acute respiratory syndrome coronavirus 2 for physicians: Molecular characteristics and host immunity (Review)

Shang J, Du L, Han N, Lv D, Wang J, Yang H, Bai L, Tang H.

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Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Zakashansky JA, Imamura AH, Salgado DF 2nd, Romero Mercieca HC, Aguas RFL, Lao AM, Pariser J, Arroyo-Currás N, Khine M.

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Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2

Weglarz-Tomczak E, Tomczak JM, Talma M, Burda-Grabowska M, Giurg M, Brul S.

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Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody

Rosenfeld R, Noy-Porat T, Mechaly A, Makdasi E, Levy Y, Alcalay R, Falach R, Aftalion M, Epstein E, Gur D, Chitlaru T, Vitner EB, Melamed S, Politi B, Zauberman A, Lazar S, Beth-Din A, Evgy Y, Yitzhaki S, Shapira SC, Israely T, Mazor O.

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Coding-Complete Genome Sequences of NITMA1086 and NITMA1139, Two SARS-CoV-2 Isolates from Belagavi District, Karnataka State, India, Harboring the D614G Mutation

Singh I, Vetrivel U, Harish DR, Chattophadhyay D.

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In Silico Study of Polyunsaturated Fatty Acids as Potential SARS-CoV-2 Spike Protein Closed Conformation Stabilizers: Epidemiological and Computational Approaches

Vivar-Sierra A, Araiza-Macías MJ, Hernández-Contreras JP, Vergara-Castañeda A, Ramírez-Vélez G, Pinto-Almazán R, Salazar JR, Loza-Mejía MA.

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Mucociliary Respiratory Epithelium Integrity in Molecular Defense and Susceptibility to Pulmonary Viral Infections

Adivitiya, Kaushik MS, Chakraborty S, Veleri S, Kateriya S.

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Effect of An 84-bp Deletion of the Receptor-Binding Domain on the ACE2 Binding Affinity of the SARS-CoV-2 Spike Protein: An In Silico Analysis

Kemenesi G, Tóth GE, Bajusz D, Keserű GM, Terhes G, Burián K, Zeghbib S, Somogyi BA, Jakab F.

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Conjugation of Mannans to Enhance the Potency of Liposome Nanoparticles for the Delivery of RNA Vaccines

Goswami R, O'Hagan DT, Adamo R, Baudner BC.

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Molecular Epidemiology Surveillance of SARS-CoV-2: Mutations and Genetic Diversity One Year after Emerging

Flores-Alanis A, Cruz-Rangel A, Rodríguez-Gómez F, González J, Torres-Guerrero CA, Delgado G, Cravioto A, Morales-Espinosa R.

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Packaging Covered with Antiviral and Antibacterial Coatings Based on ZnO Nanoparticles Supplemented with Geraniol and Carvacrol

Mizielińska M, Nawrotek P, Stachurska X, Ordon M, Bartkowiak A.

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Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion

Mondal S, Karmakar A, Mallick T, Begum NA.

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Transmission of SARS-CoV-2 among healthcare workers and patients in a teaching hospital in the Netherlands confirmed by whole genome sequencing

Paltansing S, Sikkema RS, Man SJ, Koopmans MPG, Munnink BBO, Man P.

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In silico analysis suggests less effective MHC-II presentation of SARS-CoV-2 RBM peptides: Implication for neutralizing antibody responses

Castro A, Ozturk K, Zanetti M, Carter H.

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The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types

Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE.

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Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus)

Nguyen TT, Pathirana PN, Nguyen T, Nguyen QVH, Bhatti A, Nguyen DC, Nguyen DT, Nguyen ND, Creighton D, Abdelrazek M.

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Reply to Ma and Wang: Reliability of various in vitro activity assays on SARS-CoV-2 main protease inhibitors

Li Z, Lin Y, Huang YY, Liu R, Zhan CG, Wang X, Luo HB.

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Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors

Ma C, Wang J.

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SARS-CoV-2 genome and antibodies in breastmilk: a systematic review and meta-analysis

Zhu F, Zozaya C, Zhou Q, De Castro C, Shah PS.

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Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup

Lau SKP, Lung DC, Wong EYM, Aw-Yong KL, Wong ACP, Luk HKH, Li KSM, Fung J, Chan TTY, Tang JYM, Zhu L, Yip CCY, Wong SCY, Lee RA, Tsang OTY, Yuen KY, Woo PCY.

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The Human Genome Organisation (HUGO) and the 2020 COVID-19 pandemic

Capps B, Joly Y, Mulvihill J, Lee WB; HUGO Committee on Ethics, Law and Society, and the HUGO Council.

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In Silico Investigation of the New UK (B.1.1.7) and South African (501Y.V2) SARS-CoV-2 Variants with a Focus at the ACE2-Spike RBD Interface

Villoutreix BO, Calvez V, Marcelin AG, Khatib AM.

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Rapid processing of SARS-CoV-2 containing specimens for direct RT-PCR

Chomczynski P, Chomczynski PW, Kennedy A, Rymaszewski M, Wilfinger WW, Heiny JA, Mackey K.

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A Molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses

Comella PH, Gonzalez-Kozlova E, Kosoy R, Charney AW, Peradejordi IF, Chandrasekar S, Tyler SR, Wang W, Losic B, Zhu J, Hoffman GE, Kim-Schulze S, Qi J, Patel M, Kasarskis A, Suarez-Farinas M, Gümüş ZH, Argmann C, Merad M, Becker C, Beckmann ND, Schadt EE.

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Genomic epidemiology identifies emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States

Washington NL, Gangavarapu K, Zeller M, Bolze A, Cirulli ET, Schiabor Barrett KM, Larsen BB, Anderson C, White S, Cassens T, Jacobs S, Levan G, Nguyen J, Ramirez JM, Rivera-Garcia C, Sandoval E, Wang X, Wong D, Spencer E, Robles-Sikisaka R, Kurzban E, Hughes LD, Deng X, Wang C, Servellita V, Valentine H, De Hoff P, Seaver P, Sathe S, Gietzen K, Sickler B, Antico J, Hoon K, Liu J, Harding A, Bakhtar O, Basler T, Austin B, Isaksson M, Febbo P, Becker D, Laurent M, McDonald E, Yeo GW, Knight R, Lau

Abstract:

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Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine-elicited antibodies

Tada T, Dcosta BM, Samanovic-Golden M, Herati RS, Cornelius A, Mulligan MJ, Landau NR.

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Site-specific O-glycosylation analysis of SARS-CoV-2 spike protein produced in insect and human cells

Bagdonaite I, Thompson AJ, Wang X, Søgaard M, Fougeroux C, Frank M, Diedrich JK, Yates JR, Salanti A, Vakhrushev SY, Paulson JC, Wandall HH.

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Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation

Zhang L, Mann M, Syed Z, Reynolds HM, Tian E, Samara NL, Zeldin DC, Tabak LA, Ten Hagen KG.

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Mutational hotspots and conserved domains of SARS-CoV-2 genome in African population

Omotoso OE, Babalola AD, Matareek A.

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A proposed insight into the anti-viral potential of metallic nanoparticles against novel coronavirus disease-19 (COVID-19)

Ibrahim Fouad G.

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Structural modeling and analysis of the SARS-CoV-2 cell entry inhibitor camostat bound to the trypsin-like protease TMPRSS2

Escalante DE, Ferguson DM.

Abstract:

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Nano-size dependence in the adsorption by the SARS-CoV-2 spike protein over gold colloid

Yokoyama K, Ichiki A.

Abstract:

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The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I interferon and IFITM2

Winstone H, Lista MJ, Reid AC, Bouton C, Pickering S, Galao RP, Kerridge C, Doores KJ, Swanson C, Neil S.

Abstract:

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Coumarins and Quinolones as Effective Multiple Targeted Agents Versus Covid-19: An in Silico Study

Nejabat M, Ghodsi R, Hadizadeh F.

Abstract:

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Silence of the Lambs: The Immunological and Molecular Mechanisms of COVID-19 in Children in Comparison with Adults

Cusenza F, Davino G, D'Alvano T, Argentiero A, Fainardi V, Pisi G, Principi N, Esposito S.

Abstract:

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Viral Infection and Cardiovascular Disease: Implications for the Molecular Basis of COVID-19 Pathogenesis

Seeherman S, Suzuki YJ.

Abstract:

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Repurposing potential of Ayurvedic medicinal plants derived active principles against SARS-CoV-2 associated target proteins revealed by molecular docking, molecular dynamics and MM-PBSA studies

Kumar Verma A, Kumar V, Singh S, Goswami BC, Camps I, Sekar A, Yoon S, Lee KW.

Abstract:

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"COVID-19/SARS-CoV-2 virus spike protein-related delayed inflammatory reaction to hyaluronic acid dermal fillers: a challenging clinical conundrum in diagnosis and treatment"

Munavalli GG, Guthridge R, Knutsen-Larson S, Brodsky A, Matthew E, Landau M.

Abstract:

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Genetic diversity and genomic epidemiology of SARS-CoV-2 in Morocco

Badaoui B, Sadki K, Talbi C, Salah D, Tazi L.

Abstract:

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Comparing saliva and nasopharyngeal swab specimens in the detection of COVID-19: A systematic review and meta-analysis

Nasiri K, Dimitrova A.

Abstract:

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Combined docking methods and molecular dynamics to identify effective antiviral 2, 5-diaminobenzophenonederivatives against SARS-CoV-2

Ouassaf M, Belaidi S, Mogren Al Mogren M, Chtita S, Ullah Khan S, Thet Htar T.

Abstract:

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Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera

Xie X, Liu Y, Liu J, Zhang X, Zou J, Fontes-Garfias CR, Xia H, Swanson KA, Cutler M, Cooper D, Menachery VD, Weaver SC, Dormitzer PR, Shi PY.

Abstract:

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SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity

Ozono S, Zhang Y, Ode H, Sano K, Tan TS, Imai K, Miyoshi K, Kishigami S, Ueno T, Iwatani Y, Suzuki T, Tokunaga K.

Abstract:

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Evolution of SARS-CoV-2 Envelope, Membrane, Nucleocapsid, and Spike Structural Proteins from the Beginning of the Pandemic to September 2020: A Global and Regional Approach by Epidemiological Week

Troyano-Hernáez P, Reinosa R, Holguín Á.

Abstract:

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In Silico Screening of Natural Products Isolated from Mexican Herbal Medicines against COVID-19

Rivero-Segura NA, Gomez-Verjan JC.

Abstract:

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Interaction of small molecules with the SARS-CoV-2 papain-like protease: In silico studies and in vitro validation of protease activity inhibition using an enzymatic inhibition assay

Pitsillou E, Liang J, Ververis K, Hung A, Karagiannis TC.

Abstract:

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FN3-based monobodies selective for the receptor binding domain of the SARS-CoV-2 spike protein

Miller CJ, McGinnis JE, Martinez MJ, Wang G, Zhou J, Simmons E, Amet T, Abdeen SJ, Van Huysse JW, Bowsher RR, Kay BK.

Abstract:

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The mechanism of SARS-CoV-2 nucleocapsid protein recognition by the human 14-3-3 proteins

Tugaeva KV, E D P Hawkins D, L R Smith J, Bayfield OW, Ker DS, Sysoev AA, Klychnikov OI, Antson AA, Sluchanko NN.

Abstract:

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Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

Bouwman KM, Tomris I, Turner HL, van der Woude R, Shamorkina TM, Bosman GP, Rockx B, Herfst S, Snijder J, Haagmans BL, Ward AB, Boons GJ, de Vries RP.

Abstract:

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Proteo-Genomic Analysis of SARS-CoV-2: A Clinical Landscape of Single-Nucleotide Polymorphisms, COVID-19 Proteome, and Host Responses

Tushir S, Kamanna S, Nath SS, Bhat A, Rose S, Aithal AR, Tatu U.

Abstract:

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COVID-19: molecular pathophysiology, genetic evolution and prospective therapeutics-a review

Raj CTD, Kandaswamy DK, Danduga RCSR, Rajasabapathy R, James RA.

Abstract:

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Ultraviolet-induced in situ gold nanoparticles for point-of-care testing of infectious diseases in loop-mediated isothermal amplification

Sivakumar R, Dinh VP, Lee NY.

Abstract:

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Targeting the N-terminal domain of the RNA-binding protein of the SARS-CoV-2 with high affinity natural compounds to abrogate the protein-RNA interaction: a amolecular dynamics study

Khan S, Hussain Z, Safdar M, Khan A, Wei DQ.

Abstract:

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Variability of cycle threshold values in an external quality assessment scheme for detection of the SARS-CoV-2 virus genome by RT-PCR

Buchta C, Görzer I, Chiba P, Camp JV, Holzmann H, Puchhammer-Stöckl E, Mayerhofer M, Müller MM, Aberle SW.

Abstract:

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Sustained SARS-CoV-2 nucleocapsid antibody levels in nonsevere COVID-19: a population-based study

Schaffner A, Risch L, Weber M, Thiel S, Jüngert K, Pichler M, Wohlwend N, Lung T, Ritzler M, Hillmann D, Copeland S, Renz H, Paprotny M, Risch M.

Abstract:

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Interpretable detection of novel human viruses from genome sequencing data

Bartoszewicz JM, Seidel A, Renard BY.

Abstract:

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SARSCOVIDB-A New Platform for the Analysis of the Molecular Impact of SARS-CoV-2 Viral Infection

da Rosa RL, Yang TS, Tureta EF, de Oliveira LRS, Moraes ANS, Tatara JM, Costa RP, Borges JS, Alves CI, Berger M, Guimarães JA, Santi L, Beys-da-Silva WO.

Abstract:

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Screening possible drug molecules for Covid-19. The example of vanadium (III/IV/V) complex molecules with computational chemistry and molecular docking

Vlasiou MC, Pafti KS.

Abstract:

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Bioinformatics analyses of significant genes, related pathways, and candidate diagnostic biomarkers and molecular targets in SARS-CoV-2/COVID-19

Vastrad B, Vastrad C, Tengli A.

Abstract:

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The molecular assessment of SARS-CoV-2 Nucleocapsid Phosphoprotein variants among Indian isolates

Azad GK.

Abstract:

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Structural analysis of COVID-19 spike protein in recognizing the ACE2 receptor of different mammalian species and its susceptibility to viral infection

Koley T, Madaan S, Chowdhury SR, Kumar M, Kaur P, Singh TP, Ethayathulla AS.

Abstract:

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The Biosafety and Risk Management in Preparation and Processing of Cerebrospinal Fluid and Other Neurological Specimens With Potential Coronavirus Infection

Chen CC, Chiang PC, Chen TH.

Abstract:

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Novel Targets of SARS-CoV-2 Spike Protein in Human Fetal Brain Development Suggest Early Pregnancy Vulnerability

Varma P, Lybrand ZR, Antopia MC, Hsieh J.

Abstract:

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Temperature and Latitude Correlate with SARS-CoV-2 Epidemiological Variables but not with Genomic Change Worldwide

Burra P, Soto-Díaz K, Chalen I, Gonzalez-Ricon RJ, Istanto D, Caetano-Anollés G.

Abstract:

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Detection of SARS-CoV-2 genomic RNA on surgical masks worn by patients: Proof of concept

Ruiz-Bastián M, Rodríguez-Tejedor M, Rivera-Núñez MA; SARS-CoV-2 Working Group.

Abstract:

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[Homologous modeling and binding ability analysis of Spike protein after point mutation of severe acute respiratory syndrome coronavirus 2 to receptor proteins and potential antiviral drugs]

Cao Z, Wang LT, Liu ZM.

Abstract:

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Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response

Lin JW, Tang C, Wei HC, Du B, Chen C, Wang M, Zhou Y, Yu MX, Cheng L, Kuivanen S, Ogando NS, Levanov L, Zhao Y, Li CL, Zhou R, Li Z, Zhang Y, Sun K, Wang C, Chen L, Xiao X, Zheng X, Chen SS, Zhou Z, Yang R, Zhang D, Xu M, Song J, Wang D, Li Y, Lei S, Zeng W, Yang Q, He P, Zhang Y, Zhou L, Cao L, Luo F, Liu H, Wang L, Ye F, Zhang M, Li M, Fan W, Li X, Li K, Ke B, Xu J, Yang H, He S, Pan M, Yan Y, Zha Y, Jiang L, Yu C, Liu Y, Xu Z, Li Q, Jiang Y, Sun J, Hong W, Wei H, Lu G, Vapalahti O, Luo Y, Wei

Abstract:

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An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study

Yang Z, Bogdan P, Nazarian S.

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Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2

Wrobel AG, Benton DJ, Xu P, Calder LJ, Borg A, Roustan C, Martin SR, Rosenthal PB, Skehel JJ, Gamblin SJ.

Abstract:

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Comparison of Abbott ID NOW COVID-19 rapid molecular assay to Cepheid Xpert Xpress SARS-CoV-2 assay in dry nasal swabs

Serei VD, Cristelli R, Joho K, Salaru G, Kirn T, Carayannopoulous MO, Uprety P.

Abstract:

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Is COVID-19 severity associated with anti-spike antibody duration? Data from the ARCOVID prospective observational study

Borgonovo F, Passerini M, Piscaglia M, Morena V, Giacomelli A, Oreni L, Dedivitiis G, Lupo A, Falvella S, Cossu MV, Capetti AF.

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Chloroquine: autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check?

Sharma P, McAlinden KD, Ghavami S, Deshpande DA.

Abstract:

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Molecular characterization and the mutation pattern of SARS-CoV-2 during first and second wave outbreaks in Hiroshima, Japan

Ko K, Nagashima S, E B, Ouoba S, Akita T, Sugiyama A, Ohisa M, Sakaguchi T, Tahara H, Ohge H, Ohdan H, Kubo T, Kishita E, Kuwabara M, Takahashi K, Tanaka J.

Abstract:

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An overview of molecular biology and nanotechnology based analytical methods for the detection of SARS-CoV-2: promising biotools for the rapid diagnosis of COVID-19

Kailasa SK, Mehta VN, Koduru JR, Basu H, Singhal RK, Murthy ZVP, Park TJ.

Abstract:

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In silico Screening of Natural Compounds as Potential Inhibitors of SARS-CoV-2 Main Protease and Spike RBD: Targets for COVID-19

Teli DM, Shah MB, Chhabria MT.

Abstract:

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Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs

Badary OA.

Abstract:

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Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans

Xue X, Shi J, Xu H, Qin Y, Yang Z, Feng S, Liu D, Jian L, Hua L, Wang Y, Zhang Q, Huang X, Zhang X, Li X, Chen C, Guo J, Tang W, Liu J.

Abstract:

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Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir

Bai Y, Ye F, Feng Y, Liao H, Song H, Qi J, Gao GF, Tan W, Fu L, Shi Y.

Abstract:

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Genetic polymorphisms, vitamin D binding protein and vitamin D deficiency in COVID-19

Speeckaert MM, Speeckeart R, Delanghe JR.

Abstract:

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A Neutralization Assay Based on Pseudo-Typed Lentivirus with SARS CoV-2 Spike Protein in ACE2-Expressing CRFK Cells

Pısıl Y, Shida H, Miura T.

Abstract:

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miR-24 Targets the Transmembrane Glycoprotein Neuropilin-1 in Human Brain Microvascular Endothelial Cells

Mone P, Gambardella J, Wang X, Jankauskas SS, Matarese A, Santulli G.

Abstract:

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Genomic Signatures of SARS-CoV-2 Associated with Patient Mortality

Dumonteil E, Fusco D, Drouin A, Herrera C.

Abstract:

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An Androsterone-H(2) @C(60) hybrid: Synthesis, Properties and Molecular Docking Simulations with SARS-Cov-2

Suárez M, Makowski K, Lemos R, Almagro L, Rodríguez H, Herranz MÁ, Molero D, Ortiz O, Maroto E, Albericio F, Murata Y, Martín N.

Abstract:

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Importance of Glutamine 189 flexibility in SARS-CoV-2 main protease: lesson learned from in silico virtual screening of ChEMBL database and molecular dynamics

Said MA, Albohy A, Abdelrahman MA, Ibrahim HS.

Abstract:

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SARS-CoV-2 entry inhibitors by dual targeting TMPRSS2 and ACE2: An in silico drug repurposing study

Baby K, Maity S, Mehta CH, Suresh A, Nayak UY, Nayak Y.

Abstract:

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How does large-scale genomic analysis shape our understanding of COVID variants in real time?

van Dorp L, Shey MS, Ghedin E, Michor F, Koonin EV, Hampson K.

Abstract:

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Targeting SARS-CoV-2 M3CLpro by HCV NS3/4a Inhibitors: In Silico Modeling and In Vitro Screening

Manandhar A, Blass BE, Colussi DJ, Almi I, Abou-Gharbia M, Klein ML, Elokely KM.

Abstract:

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Digging Signatures in 13-Month-Old 3xTg-AD Mice for Alzheimer's Disease and Its Disruption by Isolation Despite Social Life Since They Were Born

Gimenez-Llort L, Alveal-Mellado D.

Abstract:

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Estrogen receptors are linked to angiotensin-converting enzyme 2 (ACE2), ADAM metallopeptidase domain 17 (ADAM-17), and transmembrane protease serine 2 (TMPRSS2) expression in the human atrium: insights into COVID-19

Wang H, Sun X, L VonCannon J, Kon ND, Ferrario CM, Groban L.

Abstract:

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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

Huo J, Bas AL, Ruza RR, Duyvesteyn HME, Mikolajek H, Malinauskas T, Tan TK, Rijal P, Dumoux M, Ward PN, Ren J, Zhou D, Harrison PJ, Weckener M, Clare DK, Vogirala VK, Radecke J, Moynié L, Zhao Y, Gilbert-Jaramillo J, Knight ML, Tree JA, Buttigieg KR, Coombes N, Elmore MJ, Carroll MW, Carrique L, Shah PNM, James W, Townsend AR, Stuart DI, Owens RJ, Naismith JH.

Abstract:

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A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

Huang Q, Ji K, Tian S, Wang F, Huang B, Tong Z, Tan S, Hao J, Wang Q, Tan W, Gao GF, Yan J.

Abstract:

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Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape

McCarthy KR, Rennick LJ, Nambulli S, Robinson-McCarthy LR, Bain WG, Haidar G, Duprex WP.

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Molecular Elucidation and Therapeutic Targeting for combating COVID19: Current Scenario and Future Prospective

Suchita W, Tilotma S, Saurabh S, Abhishek K, Sagar S, Lokesh K.

Abstract:

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Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

Liu Z, VanBlargan LA, Bloyet LM, Rothlauf PW, Chen RE, Stumpf S, Zhao H, Errico JM, Theel ES, Liebeskind MJ, Alford B, Buchser WJ, Ellebedy AH, Fremont DH, Diamond MS, Whelan SPJ.

Abstract:

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Toolkit for Quickly Generating and Characterizing Molecular Probes Specific for SARS-CoV-2 Nucleocapsid as a Primer for Future Coronavirus Pandemic Preparedness

Sherwood LJ, Hayhurst A.

Abstract:

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The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera

Jangra S, Ye C, Rathnasinghe R, Stadlbauer D, Krammer F, Simon V, Martinez-Sobrido L, Garcia-Sastre A, Schotsaert M.

Abstract:

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Effect of mutations in the SARS-CoV-2 spike protein on protein stability, cleavage, and cell-cell fusion function

Barrett CT, Neal HE, Edmonds K, Moncman CL, Thompson R, Branttie JM, Boggs KB, Wu CY, Leung DW, Dutch RE.

Abstract:

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Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset

Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed H, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann DE, Finzi A.

Abstract:

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Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins

Lun CM, Waheed AA, Majadly A, Powell N, Freed EO.

Abstract:

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Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K, and N501Y variants by BNT162b2 vaccine-elicited sera

Xie X, Liu Y, Liu J, Zhang X, Zou J, Fontes-Garfias CR, Xia H, Swanson KA, Cutler M, Cooper D, Menachery VD, Weaver S, Dormitzer PR, Shi PY.

Abstract:

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Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

Dong J, Zost SJ, Greaney AJ, Starr TN, Dingens AS, Chen EC, Chen RE, Case JB, Sutton RE, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi RS, Binshtein E, Xie X, Zhan X, Shi PY, Logue J, Weston S, McGrath ME, Frieman MB, Brady T, Tuffy K, Bright H, Loo YM, McTamney P, Esser M, Carnahan RH, Diamond MS, Bloom JD, Crowe JE.

Abstract:

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Development of spike receptor-binding domain nanoparticle as a vaccine candidate against SARS-CoV-2 infection in ferrets

Kim YI, Kim D, Yu KM, Seo HD, Lee SA, Casel MAB, Jang SG, Kim S, Jung W, Lai CJ, Choi YK, Jung JU.

Abstract:

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SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines

Shen X, Tang H, McDanal C, Wagh K, Fischer W, Theiler J, Yoon H, Li D, Haynes BF, Sanders KO, Gnanakaran S, Hengartner N, Pajon R, Smith G, Dubovsky F, Glenn GM, Korber B, Montefiori DC.

Abstract:

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Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

Graudenzi A, Maspero D, Angaroni F, Piazza R, Ramazzotti D.

Abstract:

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From Genomes to Molecular Dynamics - a Bottom Up Approach in Extrication of SARS CoV-2 Main Protease Inhibitors

Aishwarya S, Gunasekaran K, Sagaya Jansi R, Sangeetha G.

Abstract:

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In silico virtual screening-based study of nutraceuticals predicts the therapeutic potentials of folic acid and its derivatives against COVID-19

Kumar V, Kancharla S, Jena MK.

Abstract:

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Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors

Osipiuk J, Azizi SA, Dvorkin S, Endres M, Jedrzejczak R, Jones KA, Kang S, Kathayat RS, Kim Y, Lisnyak VG, Maki SL, Nicolaescu V, Taylor CA, Tesar C, Zhang YA, Zhou Z, Randall G, Michalska K, Snyder SA, Dickinson BC, Joachimiak A.

Abstract:

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De novo design and bioactivity prediction of SARS-CoV-2 main protease inhibitors using recurrent neural network-based transfer learning

Santana MVS, Silva-Jr FP.

Abstract:

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Automated molecular testing of saliva for SARS-CoV-2 detection

Matic N, Lawson T, Ritchie G, Stefanovic A, Leung V, Champagne S, Romney MG, Lowe CF.

Abstract:

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Clinical and whole genome characterization of SARS-CoV-2 in India

Muttineni R, Kammili N, Bingi TC, Rao M R, Putty K, Dholaniya PS, Puli RK, Pakalapati S, S S, K S, Doodipala MR, Upadhyay AA, Bosinger SE, Amara RR, Kondapi AK.

Abstract:

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Detection of SARS-CoV-2 using real-time polymerase chain reaction in different clinical specimens: A critical review

Muhammad A, Ameer H, Haider SA, Ali I.

Abstract:

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De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

Pomplun S, Jbara M, Quartararo AJ, Zhang G, Brown JS, Lee YC, Ye X, Hanna S, Pentelute BL.

Abstract:

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Molecular dynamics analysis of phytochemicals from Ageratina adenophora against COVID-19 main protease (M(pro)) and human angiotensin-converting enzyme 2 (ACE2)

Neupane NP, Karn AK, Mukeri IH, Pathak P, Sharma PK, Singh S, Qureshi IA, Jha T, Verma A.

Abstract:

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Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis

Wu YH, Yeh IJ, Phan NN, Yen MC, Liu HL, Wang CY, Hsu HP.

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Identification of natural compounds as potent inhibitors of SARS-CoV-2 main protease using combined docking and molecular dynamics simulations

Shamim Jairajpuri D, Hussain A, Nasreen K, Mohammad T, Anjum F, Rehman T, Mustafa Hasan G, Alajmi MF, Hassan I.

Abstract:

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Presence of antibodies against SARS-CoV-2 spike protein in bovine whey IgG enriched fraction

Oshiro S, Tada T, Mizutani N, Funatogawa K, Sekiguchi JI, Takahashi M, Kirikae T.

Abstract:

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5-((1H-imidazol-1-yl)methyl)quinolin-8-ol as potential antiviral SARS-CoV-2 candidate: Synthesis, crystal structure, Hirshfeld surface analysis, DFT and molecular docking studies

Douche D, Sert Y, Brandán SA, Kawther AA, Bilmez B, Dege N, Louzi AE, Bougrin K, Karrouchi K, Himmi B.

Abstract:

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Impact of dimerization and N3 binding on molecular dynamics of SARS-CoV and SARS-CoV-2 main proteases

Tekpinar M, Yildirim A.

Abstract:

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Summary of the Available Molecular Methods for Detection of SARS-CoV-2 during the Ongoing Pandemic

Arena F, Pollini S, Rossolini GM, Margaglione M.

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Chloroquine and Hydroxychloroquine Interact Differently with ACE2 Domains Reported to Bind with the Coronavirus Spike Protein: Mediation by ACE2 Polymorphism

Badraoui R, Adnan M, Bardakci F, Alreshidi MM.

Abstract:

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Inhibitory efficiency of potential drugs against SARS-CoV-2 by blocking human angiotensin converting enzyme-2: Virtual screening and molecular dynamics study

Khan AA, Baildya N, Dutta T, Ghosh NN.

Abstract:

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Immunogenomic phases of COVID-19 and appropriate clinical management

Haznedaroglu IC.

Abstract:

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Innovative point-of-care molecular diagnostic test for COVID-19 in India

Gupta N, Rana S, Singh H.

Abstract:

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COVID-19 impacts the expression of molecular markers associated with neuropsychiatric disorders

Quincozes-Santos A, Rosa RL, Tureta EF, Bobermin LD, Berger M, Guimarães JA, Santi L, Beys-da-Silva WO.

Abstract:

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Human eggs, zygotes, and embryos express the receptor ACE2 and protease TMPRSS2 protein necessary for SARS-CoV-2 infection

Rajput SK, Logsdon DM, Kile B, Engelhorn HJ, Goheen B, Khan S, Swain J, McCormick S, Schoolcraft WB, Yuan Y, Krisher RL.

Abstract:

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Genome-wide in silico identification and characterization of Simple Sequence Repeats in diverse completed SARS-CoV-2 genomes

Siddiqe R, Ghosh A.

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The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus - evolved or yet to evolve

Budhraja A, Pandey S, Kannan S, Verma CS, Venkatraman P.

Abstract:

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Anti-IL-6 receptor antibody treatment for severe COVID-19 and the potential implication of IL-6 gene polymorphisms in novel coronavirus pneumonia

Ulhaq ZS, Soraya GV.

Abstract:

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Comprehensive and systemic optimization for improving the yield of SARS-CoV-2 spike pseudotyped virus

Fu X, Tao L, Zhang X.

Abstract:

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Generation of SARS-CoV-2 Spike Pseudotyped Virus for Viral Entry and Neutralization Assays: A 1-Week Protocol

Condor Capcha JM, Lambert G, Dykxhoorn DM, Salerno AG, Hare JM, Whitt MA, Pahwa S, Jayaweera DT, Shehadeh LA.

Abstract:

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In silico Analysis Revealed Potential Anti-SARS-CoV-2 Main Protease Activity by the Zonulin Inhibitor Larazotide Acetate

Di Micco S, Musella S, Scala MC, Sala M, Campiglia P, Bifulco G, Fasano A.

Abstract:

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Mushroom-derived bioactive compounds potentially serve as the inhibitors of SARS-CoV-2 main protease: An in silico approach

Rangsinth P, Sillapachaiyaporn C, Nilkhet S, Tencomnao T, Ung AT, Chuchawankul S.

Abstract:

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Molecular docking analysis of rutin reveals possible inhibition of SARS-CoV-2 vital proteins

Rahman F, Tabrez S, Ali R, Alqahtani AS, Ahmed MZ, Rub A.

Abstract:

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Spectroscopic investigation on the affinity of SARS-CoV-2 spike protein to gold nano-particles

Yokoyama K, Ichiki A.

Abstract:

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FDA Recommended Potent Drugs against Covid-19: Insight through Molecular Docking

Gumber K, Pomila.

Abstract:

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Biflavonoid as potential 3-chymotrypsin-like protease (3CLpro) inhibitor of SARS-Coronavirus

Hartini Y, Saputra B, Wahono B, Auw Z, Indayani F, Adelya L, Namba G, Hariono M.

Abstract:

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Comparison of pre-analytical characteristics for molecular and serological diagnostics of COVID-19

Wendt R, Nickel O, Kalbitz S, Fertey J, Ulbert S, Wolf J, Lübbert C, Borte S.

Abstract:

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Molecular mechanism, diagnosis, and potential treatment for novel coronavirus (COVID-19): a current literature review and perspective

Ratre YK, Kahar N, Bhaskar LVKS, Bhattacharya A, Verma HK.

Abstract:

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Screening of potent drug inhibitors against SARS-CoV-2 RNA polymerase: an in silico approach

Singh SK, Upadhyay AK, Reddy MS.

Abstract:

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In silico prediction of structure and function for a large family of transmembrane proteins that includes human Tmem41b

Mesdaghi S, Murphy DL, Sánchez Rodríguez F, Burgos-Mármol JJ, Rigden DJ.

Abstract:

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3-Hydroxyphthalic Anhydride-Modified Chicken Ovalbumin as a Potential Candidate Inhibits SARS-CoV-2 Infection by Disrupting the Interaction of Spike Protein With Host ACE2 Receptor

Liang T, Qiu J, Niu X, Ma Q, Zhou C, Chen P, Zhang Q, Chen M, Yang Z, Liu S, Li L.

Abstract:

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Mechanogenomic coupling of lung tissue stiffness, EMT and coronavirus pathogenicity

Uhler C, Shivashankar GV.

Abstract:

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Genome composition and genetic characterization of SARS-CoV-2

Al-Qaaneh AM, Alshammari T, Aldahhan R, Aldossary H, Alkhalifah ZA, Borgio JF.

Abstract:

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Evaluating the potency of Sulawesi propolis compounds as ACE-2 inhibitors through molecular docking for COVID-19 drug discovery preliminary study

Khayrani AC, Irdiani R, Aditama R, Pratami DK, Lischer K, Ansari MJ, Chinnathambi A, Alharbi SA, Almoallim HS, Sahlan M.

Abstract:

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Point-of-care test system for detection of immunoglobulin-G and -M against nucleocapsid protein and spike glycoprotein of SARS-CoV-2

Peng T, Sui Z, Huang Z, Xie J, Wen K, Zhang Y, Huang W, Mi W, Peng K, Dai X, Fang X.

Abstract:

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Molecular modeling evaluation of the binding effect of five protease inhibitors to COVID-19 main protease

Liu J, Zhai Y, Liang L, Zhu D, Zhao Q, Qiu Y.

Abstract:

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Structure features of peptide-type SARS-CoV main protease inhibitors: Quantitative structure activity relationship study

Masand VH, Akasapu S, Gandhi A, Rastija V, Patil MK.

Abstract:

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A computational approach for the screening of potential antiviral compounds against SARS-CoV-2 protease: Ionic liquid vs herbal and natural compounds

Saraswat J, Singh P, Patel R.

Abstract:

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Inhibitory capacity of chloroquine against SARS-COV-2 by effective binding with angiotensin converting enzyme-2 receptor: An insight from molecular docking and MD-simulation studies

Baildya N, Ghosh NN, Chattopadhyay AP.

Abstract:

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In silico assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2

Satyanarayana MV, Reddy AG, Yedukondalu M, Tej MB, Hossain KA, Rao MVB, Pal M.

Abstract:

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Molecular docking identification for the efficacy of some zinc complexes with chloroquine and hydroxychloroquine against main protease of COVID-19

Hussein RK, Elkhair HM.

Abstract:

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Identification of potential inhibitors of SARS-CoV-2 main protease from Aloe vera compounds: A molecular docking study

Mpiana PT, Ngbolua KT, Tshibangu DST, Kilembe JT, Gbolo BZ, Mwanangombo DT, Inkoto CL, Lengbiye EM, Mbadiko CM, Matondo A, Bongo GN, Tshilanda DD.

Abstract:

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Exploring the new potential antiviral constituents of Moringa oliefera for SARS-COV-2 pathogenesis: An in silico molecular docking and dynamic studies

Muhammad S, Hassan SH, Al-Sehemi AG, Shakir HA, Khan M, Irfan M, Iqbal J.

Abstract:

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Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology

Liu F, Li Y, Yang Y, Li M, Du Y, Zhang Y, Wang J, Shi Y.

Abstract:

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Virtual screening and molecular dynamics simulation study of plant-derived compounds to identify potential inhibitors of main protease from SARS-CoV-2

Mahmud S, Uddin MAR, Paul GK, Shimu MSS, Islam S, Rahman E, Islam A, Islam MS, Promi MM, Emran TB, Saleh MA.

Abstract:

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Detection of SARS-CoV-2 from patient fecal samples by whole genome sequencing

Papoutsis A, Borody T, Dolai S, Daniels J, Steinberg S, Barrows B, Hazan S.

Abstract:

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Potential inhibitors interacting in Neuropilin-1 to develop an adjuvant drug against COVID-19, by molecular docking

Vique-Sánchez JL.

Abstract:

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The Nucleocapsid protein triggers the main humoral immune response in COVID-19 patients

Smits VAJ, Hernández-Carralero E, Paz-Cabrera MC, Cabrera E, Hernández-Reyes Y, Hernández-Fernaud JR, Gillespie DA, Salido E, Hernández-Porto M, Freire R.

Abstract:

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In Response to: Multiple assays in a real-time RT-PCR Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak

Peñarrubia L, Ruiz M, Porco R, Rao SN, Vella SA, Juanola-Falgarona M, Manissero D, López-Fontanals M, Pareja J.

Abstract:

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Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development

Liu C, Boland S, Scholle MD, Bardiot D, Marchand A, Chaltin P, Blatt LM, Beigelman L, Symons JA, Raboisson P, Gurard-Levin ZA, Vandyck K, Deval J.

Abstract:

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Addendum: A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

Rambaut A, Holmes EC, O'Toole Á, Hill V, McCrone JT, Ruis C, du Plessis L, Pybus OG.

Abstract:

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Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

Madala BS, Reis ALM, Deveson IW, Rawlinson W, Mercer TR.

Abstract:

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Engaging the spikes: heparan sulfate facilitates SARS-CoV-2 spike protein binding to ACE2 and potentiates viral infection

Kalra RS, Kandimalla R.

Abstract:

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Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein

Lu Q, Zhang Z, Li H, Zhong K, Zhao Q, Wang Z, Wu Z, Yang D, Sun S, Yang N, Zheng M, Chen Q, Long C, Guo W, Yang H, Nie C, Tong A.

Abstract:

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Caged Dexamethasone/Quercetin Nanoparticles, Formed of the Morphogenetic Active Inorganic Polyphosphate, are Strong Inducers of MUC5AC

Neufurth M, Wang X, Wang S, Schröder HC, Müller WEG.

Abstract:

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Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations

Ramakrishnan J, Kandasamy S, Iruthayaraj A, Magudeeswaran S, Chinnasamy K, Poomani K.

Abstract:

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Comparison of nine different commercially available molecular assays for detection of SARS-CoV-2 RNA

Eberle U, Wimmer C, Huber I, Neubauer-Juric A, Valenza G, Ackermann N, Sing A; Bavarian SARS-CoV-2-Public Health Laboratory Team.

Abstract:

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Evolutionary analysis of SARS-CoV-2 spike protein for its different clades

Pereson MJ, Flichman DM, Martínez AP, Baré P, Garcia GH, Di Lello FA.

Abstract:

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SARS-CoV-2 Spike Protein Positivity in Pityriasis Rosea-like and Urticaria-like Rashes of COVID-19

Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, Franco-Marquez R, Arvizu-Rivera RI.

Abstract:

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Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying miRNA as a Potential Multi Target Therapy to COVID-19: an In Silico Analysis

Schultz IC, Bertoni APS, Wink MR.

Abstract:

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Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences

Yang M, He S, Chen X, Huang Z, Zhou Z, Zhou Z, Chen Q, Chen S, Kang S.

Abstract:

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Genomic epidemiology of the early stages of the SARS-CoV-2 outbreak in Russia

Komissarov AB, Safina KR, Garushyants SK, Fadeev AV, Sergeeva MV, Ivanova AA, Danilenko DM, Lioznov D, Shneider OV, Shvyrev N, Spirin V, Glyzin D, Shchur V, Bazykin GA.

Abstract:

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A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

Hattori SI, Higashi-Kuwata N, Hayashi H, Allu SR, Raghavaiah J, Bulut H, Das D, Anson BJ, Lendy EK, Takamatsu Y, Takamune N, Kishimoto N, Murayama K, Hasegawa K, Li M, Davis DA, Kodama EN, Yarchoan R, Wlodawer A, Misumi S, Mesecar AD, Ghosh AK, Mitsuya H.

Abstract:

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Genome Sequence of a SARS-CoV-2 VUI 202012/01 Strain Identified from a Patient Returning from London, England, to the Apulia Region of Italy

Loconsole D, Sallustio A, Accogli M, Centrone F, Capozzi L, Del Sambro L, Parisi A, Chironna M.

Abstract:

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Genome Sequences of 10 SARS-CoV-2 Viral Strains Obtained by Nanopore Sequencing of Nasopharyngeal Swabs in Malta

Biazzo M, Madeddu S, Elnifro E, Sultana T, Muscat J, Scerri CA, Santoro F, Pinzauti D.

Abstract:

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Genome Sequencing of a Novel Coronavirus SARS-CoV-2 Isolate from Iraq

Al-Rashedi NAM, Licastro D, Rajasekharan S, Dal Monego S, Marcello A, Munahi MG, Odda BS, Alabdali YAJ, ALObaidi LAH, Jasim A, Abdulzahra IA, Kadhim K, Awad A, Bachay M.

Abstract:

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[Mechanism and material basis of Lianhua Qingwen capsule for improving clinical cure rate of COVID-19: a study based on network pharmacology and molecular docking technology]

Yan H, Zou C.

Abstract:

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COVID-19 severity in obese patients: Potential mechanisms and molecular targets for clinical intervention

Sharma JR, Yadav UCS.

Abstract:

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Coronavirus Disease 2019 (COVID-19) in Molecular Imaging: A Systematic Review of Incidental Detection of SARS-CoV-2 Pneumonia on PET Studies

Rafiee F, Keshavarz P, Katal S, Assadi M, Nejati SF, Ebrahimian Sadabad F, Gholamrezanezhad A.

Abstract:

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Latent periodicity-2 in coronavirus SARS-CoV-2 genome: evolutionary implications

Yin C.

Abstract:

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Risque de réinfection à SARS-CoV-2 chez les personnes IgG anti-spike et/ou antinucléocapside positives

Béguelin A.

Abstract:

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Targeting novel structural and functional features of coronavirus protease nsp5 (3CL(pro), M(pro)) in the age of COVID-19

Roe MK, Junod NA, Young AR, Beachboard DC, Stobart CC.

Abstract:

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Will the emergent SARS-CoV2 B.1.1.7 lineage affect molecular diagnosis of COVID19?

Ramírez JD, Muñoz M, Patiño LH, Ballesteros N, Paniz-Mondolfi A.

Abstract:

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Mutational sensitivity of D614G in spike protein of SARS-CoV-2 in Jordan

Al-Zyoud W, Haddad H.

Abstract:

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Identification and molecular characterization of mutations in nucleocapsid phosphoprotein of SARS-CoV-2

Azad GK.

Abstract:

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Spontaneous binding of potential COVID-19 drugs (Camostat and Nafamostat) to human serine protease TMPRSS2

Zhu H, Du W, Song M, Liu Q, Herrmann A, Huang Q.

Abstract:

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Author Correction: Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

da Silva Filipe A, Shepherd JG, Williams T, Hughes J, Aranday-Cortes E, Asamaphan P, Ashraf S, Balcazar C, Brunker K, Campbell A, Carmichael S, Davis C, Dewar R, Gallagher MD, Gunson R, Hill V, Ho A, Jackson B, James E, Jesudason N, Johnson N, McWilliam Leitch EC, Li K, MacLean A, Mair D, McAllister DA, McCrone JT, McDonald SE, McHugh MP, Morris AK, Nichols J, Niebel M, Nomikou K, Orton RJ, O'Toole Á, Palmarini M, Parcell BJ, Parr YA, Rambaut A, Rooke S, Shaaban S, Shah R, Singer JB, Smollett K

Abstract:

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Performance of Saliva, Oropharyngeal Swabs, and Nasal Swabs for SARS-CoV-2 Molecular Detection: A Systematic Review and Meta-analysis

Lee RA, Herigon JC, Benedetti A, Pollock NR, Denkinger CM.

Abstract:

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Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188

Lockbaum GJ, Reyes AC, Lee JM, Tilvawala R, Nalivaika EA, Ali A, Kurt Yilmaz N, Thompson PR, Schiffer CA.

Abstract:

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Stable dechlorination of Trichloroacetic Acid (TCAA) to acetic acid catalyzed by palladium nanoparticles deposited on H(2)-transfer membranes

Cai Y, Long X, Luo YH, Zhou C, Rittmann BE.

Abstract:

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Molecular structure, NBO analysis of the hydrogen-bonded interactions, spectroscopic (FT-IR, FT-Raman), drug likeness and molecular docking of the novel anti COVID-2 molecule (2E)-N-methyl-2-[(4-oxo-4H-chromen-3-yl)methylidene]-hydrazinecarbothioamide (Dimer) - quantum chemical approach

Jenepha Mary SJ, Pradhan S, James C.

Abstract:

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Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins

Lagoumintzis G, Chasapis CT, Alexandris N, Kouretas D, Tzartos S, Eliopoulos E, Farsalinos K, Poulas K.

Abstract:

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Correction: Machine learning using intrinsic genomic signatures for rapid classification of novel pathogens: COVID-19 case study

PLOS ONE Staff.

Abstract:

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The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

Rathnasinghe R, Jangra S, Cupic A, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Mena I, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Richt JA, De Geest BG, Miorin L, Krammer F, Simon V, García-Sastre A, Schotsaert M.

Abstract:

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Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Carnahan RH, Thackray LB, Diamond MS, Crowe JE.

Abstract:

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mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants

Wu K, Werner AP, Moliva JI, Koch M, Choi A, Stewart-Jones GBE, Bennett H, Boyoglu-Barnum S, Shi W, Graham BS, Carfi A, Corbett KS, Seder RA, Edwards DK.

Abstract:

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Bispecific antibody prevents SARS-CoV-2 escape and protects mice from disease

Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Cassaniti I, Percivalle E, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Di Girolamo S, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Sammartino JC, Giardina F, Gaiarsa S, Hammarström QP, Barnes CO, Piralla A, Bjorkman PJ, Baldanti F, Calzolai L, Nussenzweig MC, Bieniasz PD, Hatziioannou T,

Abstract:

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Native-like SARS-CoV-2 spike glycoprotein expressed by ChAdOx1 nCoV-19/AZD1222 vaccine

Watanabe Y, Mendonça L, Allen ER, Howe A, Lee M, Allen JD, Chawla H, Pulido D, Donnellan F, Davies H, Ulaszewska M, Belij-Rammerstorfer S, Morris S, Krebs AS, Dejnirattisai W, Mongkolsapaya J, Supasa P, Screaton GR, Green CM, Lambe T, Zhang P, Gilbert SC, Crispin M.

Abstract:

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Synonymous mutations and the molecular evolution of SARS-CoV-2 origins

Wang H, Pipes L, Nielsen R.

Abstract:

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Molecular Docking of Azithromycin, Ritonavir, Lopinavir, Oseltamivir, Ivermectin and Heparin Interacting with Coronavirus Disease 2019 Main and Severe Acute Respiratory Syndrome Coronavirus-2 3C-Like Proteases

Arouche TDS, Martins AY, Ramalho TC, Júnior RNC, Costa FLP, Filho TSA, Neto AMJC.

Abstract:

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Biological and Clinical Consequences of Integrin Binding via a Rogue RGD Motif in the SARS CoV-2 Spike Protein

Makowski L, Olson-Sidford W, W-Weisel J.

Abstract:

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SARS-CoV-2 and other human coronavirus: Mapping of protease recognition sites, antigenic variation of spike protein and their grouping through molecular phylogenetics

Chakraborty C, Sharma AR, Bhattacharya M, Saha RP, Ghosh S, Biswas S, Samanta S, Sharma G, Agoramoorthy G, Lee SS.

Abstract:

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Repositioning of histamine H(1) receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2

Ge S, Wang X, Hou Y, Lv Y, Wang C, He H.

Abstract:

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Isolating SARS-CoV-2 Strains From Countries in the Same Meridian: Genome Evolutionary Analysis

Mastriani E, Rakov AV, Liu SL.

Abstract:

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Quantitative Assessment of SARS-CoV-2 Virus in Nasopharyngeal Swabs Stored in Transport Medium by a Straightforward LC-MS/MS Assay Targeting Nucleocapsid, Membrane, and Spike Proteins

Saadi J, Oueslati S, Bellanger L, Gallais F, Dortet L, Roque-Afonso AM, Junot C, Naas T, Fenaille F, Becher F.

Abstract:

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Early Transmission Dynamics, Spread, and Genomic Characterization of SARS-CoV-2 in Panama

Franco D, Gonzalez C, Abrego LE, Carrera JP, Diaz Y, Caicedo Y, Moreno A, Chavarria O, Gondola J, Castillo M, Valdespino E, Gaitán M, Martínez-Mandiche J, Hayer L, Gonzalez P, Lange C, Molto Y, Mojica D, Ramos R, Mastelari M, Cerezo L, Moreno L, Donnelly CA, Pascale JM, Faria NR, Lopez-Verges S, Martinez AA; Gorgas COVID19 team and Panama COVID19 Laboratory Network.

Abstract:

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Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic COVID-19 patients

Goh YS, Chavatte JM, Jieling AL, Lee B, Hor PX, Amrun SN, Yi-Pin Lee C, Sin-Ling Chee R, Wang B, Lee CY, Xian Ngoh EZ, Wang CI, Young BE, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, I-Cheng Chen M, Leo YS, Lye DC, Ng LFP, Pin Lin RT, Renia L.

Abstract:

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SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production

Luo L, Li Z, Zhao T, Ju X, Ma P, Jin B, Zhou Y, He S, Huang J, Xu X, Zou Y, Li P, Liang A, Liu J, Chi T, Huang X, Ding Q, Jin Z, Huang C, Zhang Y.

Abstract:

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Binding of the SARS-CoV-2 Spike Protein to Glycans

Hao W, Ma B, Li Z, Wang X, Gao X, Li Y, Qin B, Shang S, Cui S, Tan Z.

Abstract:

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Luteolin and abyssinone II as potential inhibitors of SARS-CoV-2: an in silico molecular modeling approach in battling the COVID-19 outbreak

Shawan MMAK, Halder SK, Hasan MA.

Abstract:

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Identification of potential SARS-CoV-2 entry inhibitors by targeting the interface region between the spike RBD and human ACE2

Gurung AB, Ali MA, Lee J, Farah MA, Al-Anazi KM.

Abstract:

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Screening, simulation, and optimization design of small molecule inhibitors of the SARS-CoV-2 spike glycoprotein

Sun C, Zhang J, Wei J, Zheng X, Zhao X, Fang Z, Xu D, Yuan H, Liu Y.

Abstract:

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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion

Papa G, Mallery DL, Albecka A, Welch LG, Cattin-Ortolá J, Luptak J, Paul D, McMahon HT, Goodfellow IG, Carter A, Munro S, James LC.

Abstract:

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Antibacterial, Antiviral, and Self-Cleaning Mats with Sensing Capabilities Based on Electrospun Nanofibers Decorated with ZnO Nanorods and Ag Nanoparticles for Protective Clothing Applications

Karagoz S, Kiremitler NB, Sarp G, Pekdemir S, Salem S, Goksu AG, Onses MS, Sozdutmaz I, Sahmetlioglu E, Ozkara ES, Ceylan A, Yilmaz E.

Abstract:

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Computational assessment of saikosaponins as adjuvant treatment for COVID-19: molecular docking, dynamics, and network pharmacology analysis

Chikhale R, Sinha SK, Wanjari M, Gurav NS, Ayyanar M, Prasad S, Khanal P, Dey YN, Patil RB, Gurav SS.

Abstract:

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Molecular docking studies of some selected gallic acid derivatives against five non-structural proteins of novel coronavirus

Umar HI, Siraj B, Ajayi A, Jimoh TO, Chukwuemeka PO.

Abstract:

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Molecular basis for the repurposing of histamine H2-receptor antagonist to treat COVID-19

Ishola AA, Joshi T, Abdulai SI, Tijjani H, Pundir H, Chandra S.

Abstract:

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Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro

Liu H, Ye F, Sun Q, Liang H, Li C, Li S, Lu R, Huang B, Tan W, Lai L.

Abstract:

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Molecular Testing of SARS-CoV-2 Infection from Blood Samples in Disseminated Intravascular Coagulation (DIC) and Elevated D-Dimer Levels

Dumache R, Daescu E, Ciocan V, MureÅŸan C, Talida C, Gavrilita D, Enache A.

Abstract:

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Molecular Docking and Molecular Dynamics Aided Virtual Search of OliveNetâ„¢ Directory for Secoiridoids to Combat SARS-CoV-2 Infection and Associated Hyperinflammatory Responses

Thangavel N, Al Bratty M, Al Hazmi HA, Najmi A, Ali Alaqi RO.

Abstract:

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Could Dermaseptin Analogue be a Competitive Inhibitor for ACE2 Towards Binding with Viral Spike Protein Causing COVID19?: Computational Investigation

Sekar PC, Rajasekaran R.

Abstract:

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Antimicrobial Activity, DFT Calculations, and Molecular Docking of Dialdehyde Cellulose/Graphene Oxide Film Against Covid-19

Dacrory S.

Abstract:

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Genomic Study of COVID-19 Corona Virus Excludes Its Origin from Recombination or Characterized Biological Sources and Suggests a Role for HERVS in Its Wide Range Symptoms

El-Shehawi AM, Alotaibi SS, Elseehy MM.

Abstract:

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Bioinformatics prediction of B and T cell epitopes within the spike and nucleocapsid proteins of SARS-CoV2

Dawood RM, El-Meguid MA, Salum GM, El-Wakeel K, Shemis M, El Awady MK.

Abstract:

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Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies

Patrick MT, Zhang H, Wasikowski R, Prens EP, Weidinger S, Gudjonsson JE, Elder JT, He K, Tsoi LC.

Abstract:

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Protein structural heterogeneity: A hypothesis for the basis of proteolytic recognition by the main protease of SARS-CoV and SARS-CoV-2

Behnam MAM.

Abstract:

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Green giant - a tiny chloroplast genome with mighty power to produce high-value proteins: history and phylogeny

Daniell H, Jin S, Zhu XG, Gitzendanner MA, Soltis DE, Soltis PS.

Abstract:

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A comparative study of human betacoronavirus spike proteins: structure, function and therapeutics

Verma J, Subbarao N.

Abstract:

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Systematic evaluation of IgG responses to SARS-CoV-2 spike protein-derived peptides for monitoring COVID-19 patients

Li Y, Lai DY, Lei Q, Xu ZW, Wang F, Hou H, Chen L, Wu J, Ren Y, Ma ML, Zhang B, Chen H, Yu C, Xue JB, Zheng YX, Wang XN, Jiang HW, Zhang HN, Qi H, Guo SJ, Zhang Y, Lin X, Yao Z, Pang P, Shi D, Wang W, Yang X, Zhou J, Sheng H, Sun Z, Shan H, Fan X, Tao SC.

Abstract:

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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

Tan TK, Rijal P, Rahikainen R, Keeble AH, Schimanski L, Hussain S, Harvey R, Hayes JWP, Edwards JC, McLean RK, Martini V, Pedrera M, Thakur N, Conceicao C, Dietrich I, Shelton H, Ludi A, Wilsden G, Browning C, Zagrajek AK, Bialy D, Bhat S, Stevenson-Leggett P, Hollinghurst P, Tully M, Moffat K, Chiu C, Waters R, Gray A, Azhar M, Mioulet V, Newman J, Asfor AS, Burman A, Crossley S, Hammond JA, Tchilian E, Charleston B, Bailey D, Tuthill TJ, Graham SP, Duyvesteyn HME, Malinauskas T, Huo J, Tree JA

Abstract:

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A stable platform for the production of virus-like particles pseudotyped with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein

Sylvie R, Ghani K, de Campos-Lima PO, Caruso M.

Abstract:

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The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing

Hanson KE, Caliendo AM, Arias CA, Hayden MK, Englund JA, Lee MJ, Loeb M, Patel R, El Alayli A, Altayar O, Patel P, Falck-Ytter Y, Lavergne V, Morgan RL, Murad MH, Sultan S, Bhimraj A, Mustafa RA.

Abstract:

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SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation into stress granules through its N-terminal intrinsically disordered region

Wang J, Shi C, Xu Q, Yin H.

Abstract:

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The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

Lu S, Ye Q, Singh D, Cao Y, Diedrich JK, Yates JR 3rd, Villa E, Cleveland DW, Corbett KD.

Abstract:

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Expression of Concern for Sah et al., "Complete Genome Sequence of a 2019 Novel Coronavirus (SARS-CoV-2) Strain Isolated in Nepal"

American Society for Microbiology.

Abstract:

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Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69-V70, France, August to December 2020

Bal A, Destras G, Gaymard A, Stefic K, Marlet J, Eymieux S, Regue H, Semanas Q, d'Aubarede C, Billaud G, Laurent F, Gonzalez C, Mekki Y, Valette M, Bouscambert M, Gaudy-Graffin C, Lina B, Morfin F, Josset L; COVID-Diagnosis HCL Study Group.

Abstract:

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In silico evaluation of lapachol derivatives binding to the Nsp9 of SARS-CoV-2

Junior NN, Santos IA, Meireles BA, Nicolau MSP, Lapa IR, Aguiar RS, Jardim ACG, José DP.

Abstract:

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EXPRESS: SARS-CoV-2 (covid-19): a short update on molecular biochemistry, pathology, diagnosis and therapeutic strategies

Ismail AAA.

Abstract:

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The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrophages

Gauthier AG, Wu J, Lin M, Sitapara R, Kulkarni A, Thakur GA, Schmidt EE, Perron JC, Ashby CR Jr, Mantell LL.

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Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients

Alosaimi B, Naeem A, Alghoribi MF, Okdah L, Hamed ME, AlYami AS, Alotaibi A, Enani M.

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Structural Analysis of Neutralizing Epitopes of the SARS-CoV-2 Spike to Guide Therapy and Vaccine Design Strategies

Finkelstein MT, Mermelstein AG, Parker Miller E, Seth PC, Stancofski ED, Fera D.

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Immune Responses Induced by mRNA Vaccination in Mice, Monkeys and Humans

Cagigi A, Loré K.

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ATP biphasically modulates LLPS of SARS-CoV-2 nucleocapsid protein and specifically binds its RNA-binding domain

Dang M, Li Y, Song J.

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The 442th amino acid residue of the spike protein is critical for the adaptation to bat hosts for SARS-related coronaviruses

Li JY, Wang Q, Liao CH, Qiu Y, Ge XY.

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Loop-mediated isothermal amplification (LAMP): An effective molecular point-of-care technique for the rapid diagnosis of coronavirus SARS-CoV-2

Chaouch M.

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In silico study indicates antimalarials as direct inhibitors of SARS-CoV-2-RNA dependent RNA polymerase

Doharey PK, Singh V, Gedda MR, Sahoo AK, Varadwaj PK, Sharma B.

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Insight into molecular characteristics of SARS-CoV-2 spike protein following D614G point mutation, a molecular dynamics study

Mahmoudi Gomari M, Rostami N, Omidi-Ardali H, Arab SS.

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Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 Virions

Kiss B, Kis Z, Pályi B, Kellermayer MSZ.

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Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents

Mody V, Ho J, Wills S, Mawri A, Lawson L, Ebert MCCJC, Fortin GM, Rayalam S, Taval S.

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Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape

Ku Z, Xie X, Davidson E, Ye X, Su H, Menachery VD, Li Y, Yuan Z, Zhang X, Muruato AE, I Escuer AG, Tyrell B, Doolan K, Doranz BJ, Wrapp D, Bates PF, McLellan JS, Weiss SR, Zhang N, Shi PY, An Z.

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Comparison of Subgenomic and Total RNA in SARS-CoV-2 Challenged Rhesus Macaques

Dagotto G, Mercado NB, Martinez DR, Hou YJ, Nkolola JP, Carnahan RH, Crowe JE Jr, Baric RS, Barouch DH.

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ACE-2-Derived Biomimetic Peptides for the Inhibition of Spike Protein of SARS-CoV-2

Panda SK, Sen Gupta PS, Biswal S, Ray AK, Rana MK.

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In silico comparative genomics of SARS-CoV-2 to determine the source and diversity of the pathogen in Bangladesh

Shishir TA, Naser IB, Faruque SM.

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Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS-CoV-2 spike protein

Horndler L, Delgado P, Abia D, Balabanov I, Martínez-Fleta P, Cornish G, Llamas MA, Serrano-Villar S, Sánchez-Madrid F, Fresno M, van Santen HM, Alarcón B.

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Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Disease in a 11 Year Old with COVID-19 Infection

Khan A, Panwala H, Ramadoss D, Khubchandani R.

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[Molecular diagnosis of COVID-19 – present experiences]

Pancer K, Nowakowska M, Kołakowska-Kulesza A, Zacharczuk K, Zasada AA, Szymański K, Wdowiak K, Hallmann E, Wolaniuk N, Wołkowicz T, Słoński A, Formińska K, Sadłocha A, Mosiej E, Gad B, Krzysztoszek A, Trzcińska A.

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Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein

Shoemark DK, Colenso CK, Toelzer C, Gupta K, Sessions RB, Davidson AD, Berger I, Schaffitzel C, Spencer J, Mulholland AJ.

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Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein

Hodge CD, Rosenberg DJ, Wilamowski M, Joachimiak A, Hura GL, Hammel M.

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Fatal neuroinvasion of SARS-CoV-2 in K18-hACE2 mice is partially dependent on hACE2 expression

Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz KA, Kurnick SA, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA.

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Small Molecules to Destabilize the ACE2-RBD Complex: A Molecular Dynamics Study for Potential COVID-19 Therapeutics

Razizadeh M, Nikfar M, Liu Y.

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Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening

Shurbaji S, El-Sherbiny IM, Alser M, Ali IH, Kordi H, Al-Sadi A, Popelka A, Benslimane F, Yacoub M, Yalcin HC.

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Elucidating Interactions Between SARS-CoV-2 Trimeric Spike Protein and ACE2 Using Homology Modeling and Molecular Dynamics Simulations

Sakkiah S, Guo W, Pan B, Ji Z, Yavas G, Azevedo M, Hawes J, Patterson TA, Hong H.

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Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy

Alteri C, Cento V, Piralla A, Costabile V, Tallarita M, Colagrossi L, Renica S, Giardina F, Novazzi F, Gaiarsa S, Matarazzo E, Antonello M, Vismara C, Fumagalli R, Epis OM, Puoti M, Perno CF, Baldanti F.

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SARS-CoV-2 Genomic Variation in Space and Time in Hospitalized Patients in Philadelphia

Everett J, Hokama P, Roche AM, Reddy S, Hwang Y, Kessler L, Glascock A, Li Y, Whelan JN, Weiss SR, Sherrill-Mix S, McCormick K, Whiteside SA, Graham-Wooten J, Khatib LA, Fitzgerald AS, Collman RG, Bushman F.

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Genome Sequencing of Sewage Detects Regionally Prevalent SARS-CoV-2 Variants

Crits-Christoph A, Kantor RS, Olm MR, Whitney ON, Al-Shayeb B, Lou YC, Flamholz A, Kennedy LC, Greenwald H, Hinkle A, Hetzel J, Spitzer S, Koble J, Tan A, Hyde F, Schroth G, Kuersten S, Banfield JF, Nelson KL.

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Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor

O'Keefe S, Roboti P, Duah KB, Zong G, Schneider H, Shi WQ, High S.

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Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages-Potential Implications for Cytokine Storm Syndrome

Karwaciak I, Sałkowska A, Karaś K, Dastych J, Ratajewski M.

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Self-Collection of Saliva Specimens as a Suitable Alternative to Nasopharyngeal Swabs for the Diagnosis of SARS-CoV-2 by RT-qPCR

Trobajo-Sanmartín C, Adelantado M, Navascués A, Guembe MJ, Rodrigo-Rincón I, Castilla J, Ezpeleta C.

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Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of Vaccine Design

Xia X.

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In silico T cell epitope identification for SARS-CoV-2: Progress and perspectives

Sohail MS, Ahmed SF, Quadeer AA, McKay MR.

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K18-hACE2 mice develop respiratory disease resembling severe COVID-19

Yinda CK, Port JR, Bushmaker T, Offei Owusu I, Purushotham JN, Avanzato VA, Fischer RJ, Schulz JE, Holbrook MG, Hebner MJ, Rosenke R, Thomas T, Marzi A, Best SM, de Wit E, Shaia C, van Doremalen N, Munster VJ.

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Rapid Development of SARS-CoV-2 Spike Protein Receptor-Binding Domain Self-Assembled Nanoparticle Vaccine Candidates

Kang YF, Sun C, Zhuang Z, Yuan RY, Zheng Q, Li JP, Zhou PP, Chen XC, Liu Z, Zhang X, Yu XH, Kong XW, Zhu QY, Zhong Q, Xu M, Zhong NS, Zeng YX, Feng GK, Ke C, Zhao JC, Zeng MS.

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Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

Jangra S, De Vrieze J, Choi A, Rathnasinghe R, Laghlali G, Uvyn A, Van Herck S, Nuhn L, Deswarte K, Zhong Z, Sanders N, Lienenklaus S, David S, Strohmeier S, Amanat F, Krammer F, Hammad H, Lambrecht BN, Coughlan L, García-Sastre A, de Geest B, Schotsaert M.

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Cell-Based High-Throughput Screening Protocol for Discovering Antiviral Inhibitors Against SARS-COV-2 Main Protease (3CLpro)

Rothan HA, Teoh TC.

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Comprehensive analysis of genomic diversity of SARS-CoV-2 in different geographic regions of India: an endeavour to classify Indian SARS-CoV-2 strains on the basis of co-existing mutations

Sarkar R, Mitra S, Chandra P, Saha P, Banerjee A, Dutta S, Chawla-Sarkar M.

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Publisher Correction: Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

da Silva Filipe A, Shepherd JG, Williams T, Hughes J, Aranday-Cortes E, Asamaphan P, Ashraf S, Balcazar C, Brunker K, Campbell A, Carmichael S, Davis C, Dewar R, Gallagher MD, Gunson R, Hill V, Ho A, Jackson B, James E, Jesudason N, Johnson N, McWilliam Leitch EC, Li K, MacLean A, Mair D, McAllister DA, McCrone JT, McDonald SE, McHugh MP, Morris AK, Nichols J, Niebel M, Nomikou K, Orton RJ, O'Toole Á, Palmarini M, Parcell BJ, Parr YA, Rambaut A, Rooke S, Shaaban S, Shah R, Singer JB, Smollett K

Abstract:

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MERS-CoV: epidemiology, molecular dynamics, therapeutics, and future challenges

Rabaan AA, Al-Ahmed SH, Sah R, Alqumber MA, Haque S, Patel SK, Pathak M, Tiwari R, Yatoo MI, Haq AU, Bilal M, Dhama K, Rodriguez-Morales AJ.

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What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design

Xiong M, Su H, Zhao W, Xie H, Shao Q, Xu Y.

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SARS-CoV-2, the pandemic coronavirus: Molecular and structural insights

Kadam SB, Sukhramani GS, Bishnoi P, Pable AA, Barvkar VT.

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Addressing the potential role of curcumin in the prevention of COVID-19 by targeting the Nsp9 replicase protein through molecular docking

Kumar M, Sodhi KK, Singh DK.

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An in silico analysis of Ibuprofen enantiomers in high concentrations of sodium chloride with SARS-CoV-2 main protease

Clemente CM, Freiberger MI, Ravetti S, Beltramo DM, Garro AG.

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Identification of 1,2,3-triazole-phthalimide derivatives as potential drugs against COVID-19: a virtual screening, docking and molecular dynamic study

Holanda VN, Lima EMA, Silva WVD, Maia RT, Medeiros RL, Ghosh A, Lima VLM, Figueiredo RCBQ.

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Molecular docking and simulation studies of natural compounds of Vitex negundo L. against papain-like protease (PL(pro)) of SARS CoV-2 (coronavirus) to conquer the pandemic situation in the world

Mitra D, Verma D, Mahakur B, Kamboj A, Srivastava R, Gupta S, Pandey A, Arora B, Pant K, Panneerselvam P, Ghosh A, Barik DP, Mohapatra PKD.

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World-wide tracking of major SARS-CoV-2 genome haplotypes in sequences of June 1 to November 15, 2020 and discovery of rapid expansion of a new haplotype

Safari I, InanlooRahatloo K, Elahi E.

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In silico validation of potent phytochemical orientin as inhibitor of SARS-CoV-2 spike and host cell receptor GRP78 binding

Bhowmik A, Biswas S, Hajra S, Saha P.

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In silico exploration of novel protease inhibitors against coronavirus 2019 (COVID-19)

Aghaee E, Ghodrati M, Ghasemi JB.

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Compounds of Citrus medica and Zingiber officinale for COVID-19 inhibition: in silico evidence for cues from Ayurveda

Haridas M, Sasidhar V, Nath P, Abhithaj J, Sabu A, Rammanohar P.

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Factual insights of the allosteric inhibition mechanism of SARS-CoV-2 main protease by quercetin: an in silico analysis

Verma S, Pandey AK.

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In silico docking analysis revealed the potential of phytochemicals present in Phyllanthus amarus and Andrographis paniculata, used in Ayurveda medicine in inhibiting SARS-CoV-2

Hiremath S, Kumar HDV, Nandan M, Mantesh M, Shankarappa KS, Venkataravanappa V, Basha CRJ, Reddy CNL.

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Protease inhibitor GC376 for COVID-19: Lessons learned from feline infectious peritonitis

Sharun K, Tiwari R, Dhama K.

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Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs

Pontes C, Ruiz-Serra V, Lepore R, Valencia A.

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Principal Component Analysis Applications in COVID-19 Genome Sequence Studies

Wang B, Jiang L.

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Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography

Kneller DW, Phillips G, Weiss KL, Pant S, Zhang Q, O'Neill HM, Coates L, Kovalevsky A.

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High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity

Lu J, Sun PD.

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Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays

Gupta Y, Maciorowski D, Zak SE, Jones KA, Kathayat RS, Azizi SA, Mathur R, Pearce CM, Ilc DJ, Husein H, Herbert AS, Bharti A, Rathi B, Durvasula R, Becker DP, Dickinson BC, Dye JM, Kempaiah P.

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Alarming COVID variants show vital role of genomic surveillance

Cyranoski D.

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SARS-CoV-2 infection susceptibility influenced by ACE2 genetic polymorphisms: insights from Tehran Cardio-Metabolic Genetic Study

Lanjanian H, Moazzam-Jazi M, Hedayati M, Akbarzadeh M, Guity K, Sedaghati-Khayat B, Azizi F, Daneshpour MS.

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Systematic Search for SARS-CoV-2 Main Protease Inhibitors for Drug Repurposing: Ethacrynic Acid as a Potential Drug

Isgrò C, Sardanelli AM, Palese LL.

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Comparative research on nucleocapsid and spike glycoprotein as the rapid immunodetection targets of COVID-19 and establishment of immunoassay strips

Liu D, Wu F, Cen Y, Ye L, Shi X, Huang Y, Fang S, Ma L.

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The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy

Mohamud Y, Xue YC, Liu H, Ng CS, Bahreyni A, Jan E, Luo H.

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First detection of SARS-CoV-2 spike protein N501 mutation in Italy in August, 2020

Fiorentini S, Messali S, Zani A, Caccuri F, Giovanetti M, Ciccozzi M, Caruso A.

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Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality

Philippe A, Chocron R, Gendron N, Bory O, Beauvais A, Peron N, Khider L, Guerin CL, Goudot G, Levasseur F, Peronino C, Duchemin J, Brichet J, Sourdeau E, Desvard F, Bertil S, Pene F, Cheurfa C, Szwebel TA, Planquette B, Rivet N, Jourdi G, Hauw-Berlemont C, Hermann B, Gaussem P, Mirault T, Terrier B, Sanchez O, Diehl JL, Fontenay M, Smadja DM.

Abstract:

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Dynamic Network Modeling of Allosteric Interactions and Communication Pathways in the SARS-CoV-2 Spike Trimer Mutants: Differential Modulation of Conformational Landscapes and Signal Transmission via Cascades of Regulatory Switches

Verkhivker GM, Di Paola L.

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In silico and in vitro evaluation of kaempferol as a potential inhibitor of the SARS-CoV-2 main protease (3CLpro)

Khan A, Heng W, Wang Y, Qiu J, Wei X, Peng S, Saleem S, Khan M, Ali SS, Wei DQ.

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Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model

Zhang Z, Zhang L, Zhu A, Wang Y, Guan W, Zeng Z, Sun J, Li F, Zhao J, Yang Z, Zhao J, Zhong N.

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Understanding COVID-19 Pandemic: Molecular Mechanisms and Potential Therapeutic Strategies. An Evidence-Based Review

Hanna R, Dalvi S, Sălăgean T, Pop ID, Bordea IR, Benedicenti S.

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SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-19

Arce VM, Costoya JA.

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