Vírus, Imunologia e Patogénese


9(1):9. doi: 10.1007/s40203-020-00071-w. eCollection 2021.","Falade VA","In Silico Pharmacol","2021","2021/01/11","PMC7786323","","10.1007/s40203-020-00071-w"

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9(1):8. doi: 10.1007/s40203-020-00062-x. eCollection 2021.","Oladipo EK","In Silico Pharmacol","2021","2021/01/11","PMC7785481","","10.1007/s40203-020-00062-x"

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13(1):4. doi: 10.1186/s13073-020-00822-6.","Ward D","Genome Med","2021","2021/01/08","PMC7790334","","10.1186/s13073-020-00822-6"

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22(1):21. doi: 10.1186/s13059-020-02228-4.","Zheng F","Genome Biol","2021","2021/01/08","PMC7789082","","10.1186/s13059-020-02228-4"

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In silico study of the potential interactions of 4'-acetamidechalcones with protein targets in SARS-CoV-2

Q Almeida-Neto FW, Castro Matos MG, Marinho EM, Marinho MM, Róseo Paula Pessoa Bezerra de Menezes R, Sampaio TL, Bandeira PN, Celedonio Fernandes CF, Magno Rodrigues Teixeira A, Marinho ES, de Lima-Neto P, Silva Dos Santos H.

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Dexamethasone inhibits SARS-CoV-2 spike pseudotyped virus viropexis by binding to ACE2

Zhang Y, Hu S, Wang J, Xue Z, Wang C, Wang N.

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In Silico Evaluation of Prospective Anti-COVID-19 Drug Candidates as Potential SARS-CoV-2 Main Protease Inhibitors

Ibrahim MAA, Abdelrahman AHM, Allemailem KS, Almatroudi A, Moustafa MF, Hegazy MF.

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Population dynamics and structural effects at short and long range support the hypothesis of the selective advantage of the G614 SARS-Cov2 spike variant

Trucchi E, Gratton P, Mafessoni F, Motta S, Cicconardi F, Mancia F, Bertorelle G, D'Annessa I, Marino DD.

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SARS-CoV-2 nucleocapsid protein intranasal inoculation induces local and systemic T cell responses in mice

He J, Huang JR, Zhang YL, Zhang J.

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Development of new vaccine target against SARS-CoV2 using envelope (E) protein: An evolutionary, molecular modeling and docking based study

Bhattacharya S, Banerjee A, Ray S.

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The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature

Machado BAS, Hodel KVS, Barbosa-Júnior VG, Soares MBP, Badaró R.

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Molecular and cellular mechanisms of liver dysfunction in COVID-19

Huang C, Li Q, Xu W, Chen L.

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Fisetin 8-C-glucoside as entry inhibitor in SARS CoV-2 infection: molecular modelling study

Mishra A, Kaur U, Singh A.

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Virtual repurposing of ursodeoxycholate and chenodeoxycholate as lead candidates against SARS-Cov2-Envelope protein: A molecular dynamics investigation

Yadav R, Choudhury C, Kumar Y, Bhatia A.

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Screening for a Potential Therapeutic Agent from the Herbal Formula in the 4(th) Edition of the Chinese National Guidelines for the Initial-Stage Management of COVID-19 via Molecular Docking

Sun Y, Yang AWH, Hung A, Lenon GB.

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Plant Molecular Farming as a Strategy Against COVID-19 - The Italian Perspective

Lico C, Santi L, Baschieri S, Noris E, Marusic C, Donini M, Pedrazzini E, Maga G, Franconi R, Di Bonito P, Avesani L.

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ACE2: the molecular doorway to SARS-CoV-2

Medina-Enríquez MM, Lopez-León S, Carlos-Escalante JA, Aponte-Torres Z, Cuapio A, Wegman-Ostrosky T.

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Design of a companion bioinformatic tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants

Massacci A, Sperandio E, D'Ambrosio L, Maffei M, Palombo F, Aurisicchio L, Ciliberto G, Pallocca M.

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Evolutionary and codon usage preference insights into spike glycoprotein of SARS-CoV-2

Malik YS, Ansari MI, Kattoor JJ, Kaushik R, Sircar S, Subbaiyan A, Tiwari R, Dhama K, Ghosh S, Tomar S, Zhang KYJ.

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Glycomics-informed glycoproteomic analysis of site-specific glycosylation for SARS-CoV-2 spike protein

Rosenbalm KE, Tiemeyer M, Wells L, Aoki K, Zhao P.

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Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2

Wong LR, Li K, Sun J, Zhuang Z, Zhao J, McCray PB Jr, Perlman S.

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In-depth blood proteome profiling analysis revealed distinct functional characteristics of plasma proteins between severe and non-severe COVID-19 patients

Park J, Kim H, Kim SY, Kim Y, Lee JS, Dan K, Seong MW, Han D.

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Multiple Recombination Events and Strong Purifying Selection at the Origin of SARS-CoV-2 Spike Glycoprotein Increased Correlated Dynamic Movements

Tagliamonte MS, Abid N, Borocci S, Sangiovanni E, Ostrov DA, Kosakovsky Pond SL, Salemi M, Chillemi G, Mavian C.

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Impact of Genetic Variability in ACE2 Expression on the Evolutionary Dynamics of SARS-CoV-2 Spike D614G Mutation

Huang SW, Miller SO, Yen CH, Wang SF.

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The Molecular Theory of Liquid Nanodroplets Energetics in Aerosols

Kaim SD.

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Spike glycoproteins: Their significance for corona viruses and receptor binding activities for pathogenesis and viral survival

Noman A, Aqeel M, Khalid N, Hashem M, Alamari S, Zafar S, Qasim M, Irshad MK, Qari SH.

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Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing

Pathak N, Chen YT, Hsu YC, Hsu NY, Kuo CJ, Tsai HP, Kang JJ, Huang CH, Chang SY, Chang YH, Liang PH, Yang JM.

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Using in silico viral kinetic models to guide therapeutic strategies during a pandemic: An example in SARS-CoV-2

Patel K, Dodds M, Gonçalves A, Kamal MA, Rayner CR, Kirkpatrick CM, Smith PF.

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Can men's increased susceptibility to COVID-19 be attributed to transmembrane protease serine 2?

Mantilla-Morales A.

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Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective

Ogunyemi OM, Gyebi GA, Elfiky AA, Afolabi SO, Ogunro OB, Adegunloye AP, Ibrahim IM.

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In silico analysis of phytochemicals as potential inhibitors of proteases involved in SARS-CoV-2 infection

Umadevi P, Manivannan S, Fayad AM, Shelvy S.

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SARS-CoV-2 Proteome Microarray for Mapping COVID-19 Antibody Interactions at Amino Acid Resolution

Wang H, Wu X, Zhang X, Hou X, Liang T, Wang D, Teng F, Dai J, Duan H, Guo S, Li Y, Yu X.

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Conservation analysis of SARS-CoV-2 spike suggests complicated viral adaptation history from bat to human

Lei KC, Zhang XD.

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In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19

Can H, Köseoğlu AE, Erkunt Alak S, Güvendi M, Döşkaya M, Karakavuk M, Gürüz AY, Ün C.

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Statistical power in COVID-19 case-control host genomic study design

Lin YC, Brooks JD, Bull SB, Gagnon F, Greenwood CMT, Hung RJ, Lawless J, Paterson AD, Sun L, Strug LJ; Genetic Epidemiology Committee of the Canadian COVID Genomics Network (CanCOGeN) HostSeq Project.

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Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study

Refaey RH, El-Ashrey MK, Nissan YM.

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ACE2 polymorphisms as potential players in COVID-19 outcome

Khayat AS, de Assumpção PP, Meireles Khayat BC, Thomaz Araújo TM, Batista-Gomes JA, Imbiriba LC, Ishak G, de Assumpção PB, Moreira FC, Burbano RR, Ribeiro-Dos-Santos A, Ribeiro-Dos-Santos ÂK, Dos Santos NPC, Dos Santos SEB.

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COVID-19 and Renin Angiotensin Aldosterone System: A Pharmacogenomic View

El Desoky ES.

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Molecular hydrogen (H(2) ) as a potential treatment for acute and chronic fatigue

Lucas K, Rosch M, Langguth P.

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Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin

Mycroft-West CJ, Su D, Pagani I, Rudd TR, Elli S, Gandhi NS, Guimond SE, Miller GJ, Meneghetti MCZ, Nader HB, Li Y, Nunes QM, Procter P, Mancini N, Clementi M, Bisio A, Forsyth NR, Ferro V, Turnbull JE, Guerrini M, Fernig DG, Vicenzi E, Yates EA, Lima MA, Skidmore MA.

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Identifying epitopes for cluster of differentiation and design of new peptides inhibitors against human SARS-CoV-2 spike RBD by an in-silico approach

Akachar J, Bouricha EM, Hakmi M, Belyamani L, El Jaoudi R, Ibrahimi A.

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Molecular Mechanisms Lead to Sex-Specific COVID-19 Prognosis and Targeted Therapies

Galbadage T, Peterson BM, Wang JS, Jayasekara A, Ramirez DA, Awada J, Walsh JP, Gunasekera RS.

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Identification of Small Molecule Inhibitors of the Deubiquitinating Activity of the SARS-CoV-2 Papain-Like Protease: in silico Molecular Docking Studies and in vitro Enzymatic Activity Assay

Pitsillou E, Liang J, Ververis K, Lim KW, Hung A, Karagiannis TC.

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Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers

Al-Sehemi AG, Olotu FA, Dev S, Pannipara M, Soliman ME, Carradori S, Mathew B.

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A Potential Peptide From Soy Cheese Produced Using Lactobacillus delbrueckii WS4 for Effective Inhibition of SARS-CoV-2 Main Protease and S1 Glycoprotein

Chourasia R, Padhi S, Chiring Phukon L, Abedin MM, Singh SP, Rai AK.

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Spike Proteins of SARS-CoV and SARS-CoV-2 Utilize Different Mechanisms to Bind With Human ACE2

Xie Y, Karki CB, Du D, Li H, Wang J, Sobitan A, Teng S, Tang Q, Li L.

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Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein

Nuovo GJ, Magro C, Shaffer T, Awad H, Suster D, Mikhail S, He B, Michaille JJ, Liechty B, Tili E.

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Naringerin as candidate drug against SARS-CoV-2: The role for TPC2 genomic variants in COVID-19

Di Maria E, Martini P, Gennarelli M.

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The molecular mechanism of domain-swapping of the C-terminal domain of the SARS coronavirus main protease

Terse VL, Gosavi S.

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Molecular epidemiology of COVID-19 in Oman: a molecular and surveillance study for the early transmission of COVID-19 in the country

Al-Mahruqi S, Al-Wahaibi A, Khan AL, Al-Jardani A, Asaf S, Alkindi H, Al-Kharusi S, Al-Rawahi AN, Al-Rawahi A, Al-Salmani M, Al-Shukri I, Al-Busaidi A, Al-Abri SS, Al-Harrasi A.

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Lipid-based vaccine nanoparticles for induction of humoral immune responses against HIV-1 and SARS-CoV-2

Park KS, Bazzill JD, Son S, Nam J, Shin SW, Ochyl LJ, Stuckey JA, Meagher JL, Chang L, Song J, Montefiori DC, LaBranche CC, Smith JL, Xu J, Moon JJ.

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Evaluation of variant frequency in SARS-CoV-2 infection-related genes utilizing lung cancer genomic database

Shibata Y, Matsumoto S, Yoh K, Goto K.

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In silico studies reveal antiviral effects of traditional Indian spices on COVID-19

Kumar B, Zaidi S, Haque S, Dasgupta N, Hussain A, Unni S, Singh V, Mishra BN.

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Dual inhibition of SARS-CoV-2 spike and main protease through a repurposed drug, rutin

Kumari A, Rajput VS, Nagpal P, Kukrety H, Grover S, Grover A.

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Design and in silico study of the novel coumarin derivatives against SARS-CoV-2 main enzymes

Özdemir M, Köksoy B, Ceyhan D, Sayın K, Erçağ E, Bulut M, Yalçın B.

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On the molecular structure of Remdesivir for the treatment of Covid-19

Sheikholeslami SM, Jahanbani A, Shao Z.

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High affinity nanobodies block SARS-CoV-2 spike receptor binding domain interaction with human angiotensin converting enzyme

Esparza TJ, Martin NP, Anderson GP, Goldman ER, Brody DL.

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SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus

Havranek KE, Jimenez AR, Acciani MD, Lay Mendoza MF, Reyes Ballista JM, Diaz DA, Brindley MA.

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SARS-Cov-2 Interactome with Human Ghost Proteome: A Neglected World Encompassing a Wealth of Biological Data

Cardon T, Fournier I, Salzet M.

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Identification of FDA approved drugs and nucleoside analogues as potential SARS-CoV-2 A1pp domain inhibitor: An in silico study

Singh AK, Kushwaha PP, Prajapati KS, Shuaib M, Gupta S, Kumar S.

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Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months

Abu-Raddad LJ, Chemaitelly H, Malek JA, Ahmed AA, Mohamoud YA, Younuskunju S, Al Kanaani Z, Al Khal A, Al Kuwari E, Butt AA, Coyle P, Jeremijenko A, Kaleeckal AH, Latif AN, Shaik RM, Abdul Rahim HF, Yassine HM, Al Kuwari MG, Al Romaihi HE, Al-Thani MH, Bertollini R.

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Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches

Tahir Ul Qamar M, Rehman A, Tusleem K, Ashfaq UA, Qasim M, Zhu X, Fatima I, Shahid F, Chen LL.

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Structure-Based Screening to Discover New Inhibitors for Papain-like Proteinase of SARS-CoV-2: An In Silico Study

Jamalan M, Barzegari E, Gholami-Borujeni F.

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Intradermal delivery of receptor-binding domain of SARS-CoV-2 spike protein with dissolvable microneedles to induce humoral and cellular responses in mice

Kuwentrai C, Yu J, Rong L, Zhang BZ, Hu YF, Gong HR, Dou Y, Deng J, Huang JD, Xu C.

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Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

da Silva Filipe A, Shepherd JG, Williams T, Hughes J, Aranday-Cortes E, Asamaphan P, Ashraf S, Balcazar C, Brunker K, Campbell A, Carmichael S, Davis C, Dewar R, Gallagher MD, Gunson R, Hill V, Ho A, Jackson B, James E, Jesudason N, Johnson N, McWilliam Leitch EC, Li K, MacLean A, Mair D, McAllister DA, McCrone JT, McDonald SE, McHugh MP, Morris AK, Nichols J, Niebel M, Nomikou K, Orton RJ, O'Toole Á, Palmarini M, Parcell BJ, Parr YA, Rambaut A, Rooke S, Shaaban S, Shah R, Singer JB, Smollett K

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Genome evolution of SARS-CoV-2 and its virological characteristics

Nakagawa S, Miyazawa T.

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Correction to: Genome evolution of SARS-CoV-2 and its virological characteristics

Nakagawa S, Miyazawa T.

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A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 Vaccine

Sun W, McCroskery S, Liu WC, Leist SR, Liu Y, Albrecht RA, Slamanig S, Oliva J, Amanat F, Schäfer A, Dinnon KH 3rd, Innis BL, García-Sastre A, Krammer F, Baric RS, Palese P.

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Comparative insight into the genomic landscape of SARS-CoV-2 and identification of mutations associated with the origin of infection and diversity

Mishra D, Suri GS, Kaur G, Tiwari M.

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The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

Conceicao C, Thakur N, Human S, Kelly JT, Logan L, Bialy D, Bhat S, Stevenson-Leggett P, Zagrajek AK, Hollinghurst P, Varga M, Tsirigoti C, Tully M, Chiu C, Moffat K, Silesian AP, Hammond JA, Maier HJ, Bickerton E, Shelton H, Dietrich I, Graham SC, Bailey D.

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Docking Prediction of Amantadine in the Receptor Binding Domain of Spike Protein of SARS-CoV-2

Baig AM, Khaleeq A, Syeda H.

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Investigation on penetration of saffron components through lipid bilayer bound to spike protein of SARS-CoV-2 using steered molecular dynamics simulation

Kordzadeh A, Ramazani Saadatabadi A, Hadi A.

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Recent Progress in the Drug Development Targeting SARS-CoV-2 Main Protease as Treatment for COVID-19

Cui W, Yang K, Yang H.

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No impact of cancer and plague-relevant FPR1 polymorphisms on COVID-19

Petrazzuolo A, Le Naour J, Vacchelli E, Gaussem P, Ellouze S, Jourdi G, Solary E, Fontenay M, Smadja DM, Kroemer G.

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Sewage surveillance for the presence of SARS-CoV-2 genome as a useful wastewater based epidemiology (WBE) tracking tool in India

Arora S, Nag A, Sethi J, Rajvanshi J, Saxena S, Shrivastava SK, Gupta AB.

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Neutralizing antibodies targeting SARS-CoV-2 spike protein

Xiaojie S, Yu L, Lei Y, Guang Y, Min Q.

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Efficient SARS-CoV-2 detection in unextracted oro-nasopharyngeal specimens by rRT-PCR with the Seegene Allplexâ„¢ 2019-nCoV assay

Freppel W, Merindol N, Rallu F, Bergevin M.

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Bioactivity Potential of Marine Natural Products from Scleractinia-Associated Microbes and In Silico Anti-SARS-COV-2 Evaluation

Zahran EM, Albohy A, Khalil A, Ibrahim AH, Ahmed HA, El-Hossary EM, Bringmann G, Abdelmohsen UR.

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Ethnic and age-specific acute lung injury/acute respiratory distress syndrome risk associated with angiotensin-converting enzyme insertion/deletion polymorphisms, implications for COVID-19: A meta-analysis

Pabalan N, Tharabenjasin P, Suntornsaratoon P, Jarjanazi H, Muanprasat C.

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CD147 as an alternative binding site for the spike protein on the surface of SARS-CoV-2

Faghihi H.

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Molecular pathways triggered by COVID-19 in different organs: ACE2 receptor-expressing cells under attack? A review

Saba L, Gerosa C, Fanni D, Marongiu F, La Nasa G, Caocci G, Barcellona D, Balestrieri A, Coghe F, Orru G, Coni P, Piras M, Ledda F, Suri JS, Ronchi A, D'Andrea F, Cau R, Castagnola M, Faa G.

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MIS-C in February 2020 and Implications of Genomic Sequencing for SARS-CoV-2

Parsons E, Timlin M, Starr C, Fries A, Wells R, Studer M, Sainato R.

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Biochemical and biophysical characterization of the main protease, 3-chymotrypsin-like protease (3CLpro) from the novel coronavirus SARS-CoV 2

Ferreira JC, Rabeh WM.

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Two SARS-CoV-2 Genome Sequences of Isolates from Rural U.S. Patients Harboring the D614G Mutation, Obtained Using Nanopore Sequencing

Jenjaroenpun P, Wanchai V, Ono-Moore KD, Laudadio J, James LP, Adams SH, Prior F, Nookaew I, Ussery DW, Wongsurawat T.

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Evaluation of lockdown effect on SARS-CoV-2 dynamics through viral genome quantification in waste water, Greater Paris, France, 5 March to 23 April 2020

Wurtzer S, Marechal V, Mouchel JM, Maday Y, Teyssou R, Richard E, Almayrac JL, Moulin L.

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The impact of obesity on the cellular and molecular pathophysiology of COVID-19

Dhanraj P, Pitere R, Pepper MS.

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Effect of nelfinavir stereoisomers on coronavirus main protease: Molecular docking, molecular dynamics simulation and MM/GBSA study

Sargolzaei M.

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Genomic sequencing effort for SARS-CoV-2 by country during the pandemic

Furuse Y.

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Genomic epidemiology reveals multiple introductions and spread of SARS-CoV-2 in the Indian state of Karnataka

Pattabiraman C, Habib F, P K H, Rasheed R, Prasad P, Reddy V, Dinesh P, Damodar T, Hosallimath K, George AK, Kiran Reddy NV, John B, Pattanaik A, Kumar N, Mani RS, Venkataswamy MM, Shahul Hameed SK, Kumar B G P, Desai A, Vasanthapuram R.

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Recombination events are concentrated in the spike protein region of Betacoronaviruses

Bobay LM, O'Donnell AC, Ochman H.

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Dysregulation of the mevalonate pathway during SARS-CoV-2 infection: An in silico study

Gomez Marti JL, Wells A, Brufsky AM.

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Comparative molecular dynamics study of the receptor-binding domains in SARS-CoV-2 and SARS-CoV and the effects of mutations on the binding affinity

Rezaei S, Sefidbakht Y, Uskoković V.

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Binding of SARS-CoV-2 spike protein to ACE2 is disabled by thiol-based drugs; evidence from in vitro SARS-CoV-2 infection studies

Khanna K, Raymond W, Charbit AR, Jin J, Gitlin I, Tang M, Sperber HS, Franz S, Pillai S, Simmons G, Fahy JV.

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Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice

Cao X, Tian Y, Nguyen V, Zhang Y, Gao C, Yin R, Carver W, Fan D, Albrecht H, Cui T, Tan W.

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Oligonucleotide Capture Sequencing of the SARS-CoV-2 Genome and Subgenomic Fragments from COVID-19 Individuals

Doddapaneni H, Cregeen SJ, Sucgang R, Meng Q, Qin X, Avadhanula V, Chao H, Menon V, Nicholson E, Henke D, Piedra FA, Rajan A, Momin Z, Kottapalli K, Hoffman KL, Sedlazeck FJ, Metcalf G, Piedra PA, Muzny DM, Petrosino JF, Gibbs RA.

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Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors

Ma C, Hu Y, Townsend JA, Lagarias PI, Marty MT, Kolocouris A, Wang J.

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Probing the Dynamic Structure-Function and Structure-Free Energy Relationships of the Coronavirus Main Protease with Biodynamics Theory

Wan H, Aravamuthan V, Pearlstein RA.

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Whole Genome Identification of Potential G-Quadruplexes and Analysis of the G-Quadruplex Binding Domain for SARS-CoV-2

Zhang R, Xiao K, Gu Y, Liu H, Sun X.

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Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2

Zhu Y, Xie DY.

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Analysis of Indian SARS-CoV-2 Genomes Reveals Prevalence of D614G Mutation in Spike Protein Predicting an Increase in Interaction With TMPRSS2 and Virus Infectivity

Raghav S, Ghosh A, Turuk J, Kumar S, Jha A, Madhulika S, Priyadarshini M, Biswas VK, Shyamli PS, Singh B, Singh N, Singh D, Datey A, Avula K, Smita S, Sabat J, Bhattacharya D, Kshatri JS, Vasudevan D, Suryawanshi A, Dash R, Senapati S, Beuria TK, Swain R, Chattopadhyay S, Syed GH, Dixit A, Prasad P; Odisha COVID-19 Study Group; ILS COVID-19 Team, Pati S, Parida A.

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Modulation of Autophagy by SARS-CoV-2: A Potential Threat for Cardiovascular System

Randhawa PK, Scanlon K, Rappaport J, Gupta MK.

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A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge

Yahalom-Ronen Y, Tamir H, Melamed S, Politi B, Shifman O, Achdout H, Vitner EB, Israeli O, Milrot E, Stein D, Cohen-Gihon I, Lazar S, Gutman H, Glinert I, Cherry L, Vagima Y, Lazar S, Weiss S, Ben-Shmuel A, Avraham R, Puni R, Lupu E, Bar-David E, Sittner A, Erez N, Zichel R, Mamroud E, Mazor O, Levy H, Laskar O, Yitzhaki S, Shapira SC, Zvi A, Beth-Din A, Paran N, Israely T.

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Emergence and Reemergence of Human Coronaviruses: Spike Protein as the Potential Molecular Switch and Pharmaceutical Target

Ahmad F, Kamal MA, Tekwani BL.

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Genetic and Acquired Heterotopic Ossification: A Translational Tale of Mice and Men

Cappato S, Gamberale R, Bocciardi R, Brunelli S.

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Genomic Epidemiology of the First Wave of SARS-CoV-2 in Italy

Di Giallonardo F, Duchene S, Puglia I, Curini V, Profeta F, Cammà C, Marcacci M, Calistri P, Holmes EC, Lorusso A.

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The riddle of the Sphinx: why sphingosine-1-phosphate may help define molecular mechanisms underlying risk stratification for serious COVID-19 infections

Rosen H, Oldstone MBA.

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mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2

Hassert M, Geerling E, Stone ET, Steffen TL, Feldman MS, Dickson AL, Class J, Richner JM, Brien JD, Pinto AK.

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Genomic analysis of SARS-CoV-2 reveals local viral evolution in Ghana

Ngoi JM, Quashie PK, Morang'a CM, Bonney JH, Amuzu DS, Kumordjie S, Asante IA, Bonney EY, Eshun M, Boatemaa L, Magnusen V, Kotey EN, Ndam NT, Tei-Maya F, Arjarquah AK, Obodai E, Otchere ID, Bediako Y, Mutungi JK, Amenga-Etego LN, Odoom JK, Anang AK, Kyei GB, Adu B, Ampofo WK, Awandare GA.

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Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2

Ghahremanpour MM, Tirado-Rives J, Deshmukh M, Ippolito JA, Zhang CH, Cabeza de Vaca I, Liosi ME, Anderson KS, Jorgensen WL.

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Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19

Woodhall M, Mitchell JW, Gibbons E, Healy S, Waters P, Huda S.

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Taming the Autophagy as a Strategy for Treating COVID-19

García-Pérez BE, González-Rojas JA, Salazar MI, Torres-Torres C, Castrejón-Jiménez NS.

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A Computer-Aided Drug Design Approach to Predict Marine Drug-Like Leads for SARS-CoV-2 Main Protease Inhibition

Gaudêncio SP, Pereira F.

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Molecular Docking Study on Several Benzoic Acid Derivatives against SARS-CoV-2

Stefaniu A, Pirvu L, Albu B, Pintilie L.

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A computational approach to design potential siRNA molecules as a prospective tool for silencing nucleocapsid phosphoprotein and surface glycoprotein gene of SARS-CoV-2

Chowdhury UF, Sharif Shohan MU, Hoque KI, Beg MA, Sharif Siam MK, Moni MA.

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Evaluation of NGS-based approaches for SARS-CoV-2 whole genome characterisation

Charre C, Ginevra C, Sabatier M, Regue H, Destras G, Brun S, Burfin G, Scholtes C, Morfin F, Valette M, Lina B, Bal A, Josset L.

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Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients

Ma X, Guan C, Chen R, Wang Y, Feng S, Wang R, Qu G, Zhao S, Wang F, Wang X, Zhang D, Liu L, Liao A, Yuan S.

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Autophagy in T cells from aged donors is maintained by spermidine, and correlates with function and vaccine responses

Alsaleh G, Panse I, Swadling L, Zhang H, Richter F, Meyer A, Lord J, Barnes E, Klenerman P, Green C, Simon AK.

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Multitarget in silico studies of Ocimum menthiifolium, family Lamiaceae against SARS-CoV-2 supported by molecular dynamics simulation

Albohy A, Zahran EM, Abdelmohsen UR, Salem MA, Al-Warhi T, Al-Sanea MM, Abelyan N, Khalil HE, Desoukey SY, Fouad MA, Kamel MS.

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Characterization of a Pan-Immunoglobulin Assay Quantifying Antibodies Directed against the Receptor Binding Domain of the SARS-CoV-2 S1-Subunit of the Spike Protein: A Population-Based Study

Schaffner A, Risch L, Aeschbacher S, Risch C, Weber MC, Thiel SL, Jüngert K, Pichler M, Grossmann K, Wohlwend N, Lung T, Hillmann D, Bigler S, Bodmer T, Imperiali M, Renz H, Kohler P, Vernazza P, Kahlert CR, Twerenbold R, Paprotny M, Conen D, Risch M.

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Ensemble Docking Coupled to Linear Interaction Energy Calculations for Identification of Coronavirus Main Protease (3CL(pro)) Non-Covalent Small-Molecule Inhibitors

Jukič M, Janežič D, Bren U.

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Computational Drug Repurposing Study of the RNA Binding Domain of SARS-CoV-2 Nucleocapsid Protein with Antiviral Agents

Tatar G, Ozyurt E, Turhan K.

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Chasing COVID-19 through SARS-CoV-2 spike glycoprotein

Saxena SK, Kumar S, Baxi P, Srivastava N, Puri B, Ratho RK.

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Metabolic Perturbations and Severe COVID-19 Disease: Implication of Molecular Pathways

Nigro E, Perrotta F, Polito R, D'Agnano V, Scialò F, Bianco A, Daniele A.

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Structural and functional comparison of SARS-CoV-2-spike receptor binding domain produced in Pichia pastoris and mammalian cells

Argentinian AntiCovid Consortium.

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Genomic epidemiology reveals transmission patterns and dynamics of SARS-CoV-2 in Aotearoa New Zealand

Geoghegan JL, Ren X, Storey M, Hadfield J, Jelley L, Jefferies S, Sherwood J, Paine S, Huang S, Douglas J, Mendes FK, Sporle A, Baker MG, Murdoch DR, French N, Simpson CR, Welch D, Drummond AJ, Holmes EC, Duchêne S, de Ligt J.

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Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects

Nguyen HT, Zhang S, Wang Q, Anang S, Wang J, Ding H, Kappes JC, Sodroski J.

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Lung and Kidney ACE2 and TMPRSS2 in Renin Angiotensin System Blocker Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19

Batchu SN, Kaur H, Yerra VG, Advani SL, Kabir MG, Liu Y, Klein T, Advani A.

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Dynamic Anti-Spike Protein Antibody Profiles in COVID-19 Patients

Bao Y, Ling Y, Chen YY, Tian D, Zhao GP, Zhang XH, Hong H, Li Y, Su B, Lu HZ, Xu J, Wang Y.

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The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition

Hattori T, Koide A, Noval MG, Panchenko T, Romero LA, Wen Teng K, Tada T, Landau NR, Stapleford KA, Koide S.

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Potential SARS-CoV-2 main protease inhibitors

Banerjee R, Perera L, Tillekeratne LMV.

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In silico trial to test COVID-19 candidate vaccines: a case study with UISS platform

Russo G, Pennisi M, Fichera E, Motta S, Raciti G, Viceconti M, Pappalardo F.

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D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

Weissman D, Alameh MG, de Silva T, Collini P, Hornsby H, Brown R, LaBranche CC, Edwards RJ, Sutherland L, Santra S, Mansouri K, Gobeil S, McDanal C, Pardi N, Hengartner N, Lin PJC, Tam Y, Shaw PA, Lewis MG, Boesler C, Åžahin U, Acharya P, Haynes BF, Korber B, Montefiori DC.

Abstract:

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SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

Elizondo V, Harkins GW, Mabvakure B, Smidt S, Zappile P, Marier C, Maurano M, Perez V, Mazza N, Beloso C, Ifran S, Fernandez M, Santini A, Perez V, Estevez V, Nin M, Manrique G, Perez L, Ross F, Boschi S, Zubillaga MN, Balleste R, Dellicour S, Heguy A, Duerr R.

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Thermal inactivation of COVID-19 specimens improves RNA quality and quantity

Hemati M, Soosanabadi M, Ghorashi T, Ghaffari H, Vahedi A, Sabbaghian E, Rasouli Nejad Z, Salati A, Danaei N, Kokhaei P.

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Structure-aided ACEI-capped remdesivir-loaded novel PLGA nanoparticles: toward a computational simulation design for anti-SARS-CoV-2 therapy

Wu J, Wang H, Li B.

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Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2

Zhu Z, Meng K, Meng G.

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The biogenesis of SARS-CoV-2 spike glycoprotein: multiple targets for host-directed antiviral therapy

Santopolo S, Riccio A, Santoro MG.

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Silybin B and Cianidanol Inhibit M pro and Spike Protein of SARS-CoV-2: Evidence from in Silico Molecular Docking Studies

Srivastava R, Tripathi S, Unni S, Hussain A, Haque S, Dasgupta N, Singh V, Mishra BN.

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Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2

Hatmal MM, Alshaer W, Al-Hatamleh MAI, Hatmal M, Smadi O, Taha MO, Oweida AJ, Boer JC, Mohamud R, Plebanski M.

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A molecular docking study of EGCG and theaflavin digallate with the druggable targets of SARS-CoV-2

Mhatre S, Naik S, Patravale V.

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Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells

Stuible M, Gervais C, Lord-Dufour S, Perret S, L'Abbé D, Schrag J, St-Laurent G, Durocher Y.

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Biflavonoids from Rhus succedanea as probable natural inhibitors against SARS-CoV-2: a molecular docking and molecular dynamics approach

Lokhande K, Nawani N, K Venkateswara S, Pawar S.

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Repurposing of some anti-infective drugs for COVID-19 treatment: a surveillance study supported by an in silico investigation

Sayed AM, Khalaf AM, Abdelrahim MEA, Elgendy MO.

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SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2

Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY.

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Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic

Lubin JH, Zardecki C, Dolan EM, Lu C, Shen Z, Dutta S, Westbrook JD, Hudson BP, Goodsell DS, Williams JK, Voigt M, Sarma V, Xie L, Venkatachalam T, Arnold S, Alvarado LHA, Catalfano K, Khan A, McCarthy E, Staggers S, Tinsley B, Trudeau A, Singh J, Whitmore L, Zheng H, Benedek M, Currier J, Dresel M, Duvvuru A, Dyszel B, Fingar E, Hennen EM, Kirsch M, Khan AA, Labrie-Cleary C, Laporte S, Lenkeit E, Martin K, Orellana M, de la Campa MO, Paredes I, Wheeler B, Rupert A, Sam A, See K, Zapata SS, Crai

Abstract:

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Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis

Bull RA, Adikari TN, Ferguson JM, Hammond JM, Stevanovski I, Beukers AG, Naing Z, Yeang M, Verich A, Gamaarachchi H, Kim KW, Luciani F, Stelzer-Braid S, Eden JS, Rawlinson WD, van Hal SJ, Deveson IW.

Abstract:

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New Consensus pattern in Spike CoV-2: potential implications in coagulation process and cell-cell fusion

Buonvino S, Melino S.

Abstract:

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Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility

Wang F, Huang S, Gao R, Zhou Y, Lai C, Li Z, Xian W, Qian X, Li Z, Huang Y, Tang Q, Liu P, Chen R, Liu R, Li X, Tong X, Zhou X, Bai Y, Duan G, Zhang T, Xu X, Wang J, Yang H, Liu S, He Q, Jin X, Liu L.

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Variable sensitivity in molecular detection of SARS-CoV-2 in European Expert Laboratories: External Quality Assessment, June - July 2020

Fischer C, Mögling R, Melidou A, Kühne A, Oliveira-Filho EF, Wolff T, Reiche J, Broberg E, Meijer A, Leitmeyer K, Drexler JF, Reusken CBEM.

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In vitro antimicrobial, physicochemical, pharmacokinetics and molecular docking studies of benzoyl uridine esters against SARS-CoV-2 main protease

Matin MM, Uzzaman M, Chowdhury SA, Bhuiyan MMH.

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Novel Molecular Evidence Related to COVID-19 in Patients with Diabetes Mellitus

Liao YH, Zheng JQ, Zheng CM, Lu KC, Chao YC.

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SARS-CoV-2 Spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity

Petruk G, Puthia M, Petrlova J, Samsudin F, Strömdahl AC, Cerps S, Uller L, Kjellström S, Bond PJ, Schmidtchen A.

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Identification of a SARS-like bat coronavirus that shares structural features with the spike glycoprotein receptor-binding domain of SARS-CoV-2

Fraguas Bringas C, Booth D.

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Comprehensive in silico identification of impacts of ACE2 SNPs on COVID-19 susceptibility in different populations

Paniri A, Hosseini MM, Eslam MM, Akhavan-Niaki H.

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Molecular docking, molecular dynamics, and in vitro studies reveal the potential of angiotensin II receptor blockers to inhibit the COVID-19 main protease

Alnajjar R, Mostafa A, Kandeil A, Al-Karmalawy AA.

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The Impact of Diabetes Mellitus in COVID-19: A Mechanistic Review of Molecular Interactions

Yaribeygi H, Sathyapalan T, Jamialahmadi T, Sahebkar A.

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Are losartan and imatinib effective against SARS-CoV2 pathogenesis? A pathophysiologic-based in silico study

Nejat R, Sadr AS.

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Evaluation of the Binding Affinity of Anti-Viral Drugs against Main Protease of SARS-CoV-2 through a Molecular Docking Study

Mondal M, Sarkar C, Jamaddar S, Khalipha ABR, Islam MT, Mahafzah A, Mubarak MS.

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Molecular descriptors of some chemicals that prevent COVID-19

Mondal S, De N, Pal A, Gao W.

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Depicting the inhibitory potential of polyphenols from Isatis indigotica root against the main protease of SARS CoV-2 using computational approaches

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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Interrelated Mechanism by Which the Methide Quinone Celastrol, Obtained from the Roots of Tripterygium wilfordii, Inhibits Main Protease 3CL(pro) of COVID-19 and Acts as Superoxide Radical Scavenger

Caruso F, Singh M, Belli S, Berinato M, Rossi M.

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In silico screening of potential anti-COVID-19 bioactive natural constituents from food sources by molecular docking

Xu J, Gao L, Liang H, Chen SD.

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Genomic and evolutionary comparison between SARS-CoV-2 and other human coronaviruses

Chen Z, Boon SS, Wang MH, Chan RWY, Chan PKS.

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MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples

Chen C, Li J, Di L, Jing Q, Du P, Song C, Li J, Li Q, Cao Y, Xie XS, Wu AR, Zeng H, Huang Y, Wang J.

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A Study of Policies and Guidelines for Collecting, Processing, and Storing Coronavirus Disease 2019-Patient Biospecimens for Biobanking and Research

Gao F, Tao L, Ma X, Lewandowski D, Shu Z.

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A SARS-CoV-2 Reference Standard Quantified by Multiple Digital PCR Platforms for Quality Assessment of Molecular Tests

Zhou H, Liu D, Ma L, Ma T, Xu T, Ren L, Li L, Xu S.

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Virtual screening of phytoconstituents from miracle herb nigella sativa targeting nucleocapsid protein and papain-like protease of SARS-CoV-2 for COVID-19 treatment

Siddiqui S, Upadhyay S, Ahmad R, Gupta A, Srivastava A, Trivedi A, Husain I, Ahmad B, Ahamed M, Khan MA.

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Repurposing potential of FDA approved and investigational drugs for COVID-19 targeting SARS-CoV-2 spike and main protease and validation by machine learning algorithm

Verma AK, Aggarwal R.

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The main protease and RNA-dependent RNA polymerase are two prime targets for SARS-CoV-2

Jin Z, Wang H, Duan Y, Yang H.

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Molecular epidemiology of SARS-CoV-2 clusters caused by asymptomatic cases in Anhui Province, China

Yuan Y, He J, Gong L, Li W, Jiang L, Liu J, Chen Q, Yu J, Hou S, Shi Y, Lu S, Zhang Z, Ge Y, Sa N, He L, Wu J, Sun Y, Liu Z.

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Geranii Herba as a Potential Inhibitor of SARS-CoV-2 Main 3CL(pro), Spike RBD, and Regulation of Unfolded Protein Response: An In Silico Approach

Arokiyaraj S, Stalin A, Kannan BS, Shin H.

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Persistent Detection and Infectious Potential of SARS-CoV-2 Virus in Clinical Specimens from COVID-19 Patients

Zapor M.

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An insight into the interaction between α-ketoamide- based inhibitor and coronavirus main protease: A detailed in silico study

Banerjee S.

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In silico mutagenesis of human ACE2 with S protein and translational efficiency explain SARS-CoV-2 infectivity in different species

Delgado Blanco J, Hernandez-Alias X, Cianferoni D, Serrano L.

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A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*

Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR.

Abstract:

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Low bioavailability hinders drug discovery against COVID-19, guided by in silico docking

Dey P.

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Potential Use of Antigen-Based Rapid Test for SARS-CoV-2 in Respiratory Specimens in Low-Resource Settings in Egypt for Symptomatic Patients and High-Risk Contacts

Abdelrazik AM, Elshafie SM, Abdelaziz HM.

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Development of Patient-Derived Human Monoclonal Antibodies Against Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus 2 for Coronavirus Disease 2019 Diagnosis

Zhang L, Zheng B, Gao X, Zhang L, Pan H, Qiao Y, Suo G, Zhu F.

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Modeling and simulations of CoViD-19 molecular mechanism induced by cytokines storm during SARS-CoV2 infection

Yu Z, Ellahi R, Nutini A, Sohail A, Sait SM.

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Drug repurposing for identification of potential inhibitors against SARS-CoV-2 spike receptor-binding domain: An in silico approach

Behera SK, Mahapatra N, Tripathy CS, Pati S.

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ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease

Singh H, Choudhari R, Nema V, Khan AA.

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CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Wang K, Chen W, Zhang Z, Deng Y, Lian JQ, Du P, Wei D, Zhang Y, Sun XX, Gong L, Yang X, He L, Zhang L, Yang Z, Geng JJ, Chen R, Zhang H, Wang B, Zhu YM, Nan G, Jiang JL, Li L, Wu J, Lin P, Huang W, Xie L, Zheng ZH, Zhang K, Miao JL, Cui HY, Huang M, Zhang J, Fu L, Yang XM, Zhao Z, Sun S, Gu H, Wang Z, Wang CF, Lu Y, Liu YY, Wang QY, Bian H, Zhu P, Chen ZN.

Abstract:

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Molecular docking of potential SARS-CoV-2 papain-like protease inhibitors

Li D, Luan J, Zhang L.

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Techniques assisting peptide vaccine and peptidomimetic design. Sidechain exposure in the SARS-CoV-2 spike glycoprotein

Robson B.

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Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Volz E, Hill V, McCrone JT, Price A, Jorgensen D, O'Toole Á, Southgate J, Johnson R, Jackson B, Nascimento FF, Rey SM, Nicholls SM, Colquhoun RM, da Silva Filipe A, Shepherd J, Pascall DJ, Shah R, Jesudason N, Li K, Jarrett R, Pacchiarini N, Bull M, Geidelberg L, Siveroni I; COG-UK Consortium, Goodfellow I, Loman NJ, Pybus OG, Robertson DL, Thomson EC, Rambaut A, Connor TR.

Abstract:

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A Study of Potential SARS-CoV-2 Antiviral Drugs and Preliminary Research of Their Molecular Mechanism, Based on Anti-SARS-CoV Drug Screening and Molecular Dynamics Simulation

Zhao X, Liu R, Miao Z, Ye N, Lu W.

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Deciphering the Molecular Details of the Lipoxin Formation Mechanism in the 5(S),15(S)-DiHpETE Biosynthetic Pathway Catalyzed by Reticulocyte 15-Lipoxygenase-1

Cruz A, González-Lafont À, Lluch JM.

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Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An In Silico Analysis

Dar HA, Waheed Y, Najmi MH, Ismail S, Hetta HF, Ali A, Muhammad K.

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First COVID-19 molecular docking with a chalcone-based compound: synthesis, single-crystal structure and Hirshfeld surface analysis study

Alsafi MA, Hughes DL, Said MA.

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Identifying and repurposing antiviral drugs against severe acute respiratory syndrome coronavirus 2 with in silico and in vitro approaches

Watashi K.

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Molecular characterization of SARS-CoV-2

Dërmaku-Sopjani M, Sopjani M.

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Establishment of Murine Hybridoma Cells Producing Antibodies against Spike Protein of SARS-CoV-2

Antipova NV, Larionova TD, Siniavin AE, Nikiforova MA, Gushchin VA, Babichenko II, Volkov AV, Shakhparonov MI, Pavlyukov MS.

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Investigation of beta-lactoglobulin derived bioactive peptides against SARS-CoV-2 (COVID-19): In silico analysis

Çakır B, Okuyan B, Şener G, Tunali-Akbay T.

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Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

Zhou T, Tsybovsky Y, Gorman J, Rapp M, Cerutti G, Chuang GY, Katsamba PS, Sampson JM, Schön A, Bimela J, Boyington JC, Nazzari A, Olia AS, Shi W, Sastry M, Stephens T, Stuckey J, Teng IT, Wang P, Wang S, Zhang B, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD.

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Non-Receptor-Mediated Lipid Membrane Permeabilization by the SARS-CoV-2 Spike Protein S1 Subunit

Asandei A, Mereuta L, Schiopu I, Park J, Seo CH, Park Y, Luchian T.

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(1)H, (13)C, and (15)N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein

Korn SM, Lambertz R, Fürtig B, Hengesbach M, Löhr F, Richter C, Schwalbe H, Weigand JE, Wöhnert J, Schlundt A.

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Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor

O'Keefe S, Roboti P, Duah KB, Zong G, Schneider H, Shi WQ, High S.

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The SARS-COV-2 Spike Protein Binds Sialic Acids and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device

Baker AN, Richards SJ, Guy CS, Congdon TR, Hasan M, Zwetsloot AJ, Gallo A, Lewandowski JR, Stansfeld PJ, Straube A, Walker M, Chessa S, Pergolizzi G, Dedola S, Field RA, Gibson MI.

Abstract:

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COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies

Yang Y, Zhao Y, Zhang F, Zhang L, Li L.

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Modeling the Molecular Impact of SARS-CoV-2 Infection on the Renin-Angiotensin System

Pucci F, Bogaerts P, Rooman M.

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Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R, Veverka V, Boura E.

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In silico immune infiltration profiling combined with functional enrichment analysis reveals a potential role for naïve B cells as a trigger for severe immune responses in the lungs of COVID-19 patients

Wu YY, Wang SH, Wu CH, Yen LC, Lai HF, Ho CL, Chiu YL.

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Remdesivir Strongly Binds to Both RNA-Dependent RNA Polymerase and Main Protease of SARS-CoV-2: Evidence from Molecular Simulations

Nguyen HL, Thai NQ, Truong DT, Li MS.

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Genomic characterization of SARS-CoV-2 in Egypt

Zekri AN, Easa Amer K, Hafez MM, Hassan ZK, Ahmed OS, Soliman HK, Bahnasy AA, Abdel Hamid W, Gad A, Ali M, Hassan W, Samir M, Raouf A, Khattab AA, Salah El Din Hamdy M, Sherif Soliman M, Hamdi El Sissy M, Mohamed El Khateeb S, Hosny Ezzelarab M, Fathalla LA, Abouelhoda M.

Abstract:

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New Consensus pattern in Spike CoV-2: potential implications in coagulation process and cell-cell fusion

Buonvino S, Melino S.

Abstract:

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Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models

Wang G, Yang ML, Duan ZL, Liu FL, Jin L, Long CB, Zhang M, Tang XP, Xu L, Li YC, Kamau PM, Yang L, Liu HQ, Xu JW, Chen JK, Zheng YT, Peng XZ, Lai R.

Abstract:

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Synthesis, molecular docking, and in silico ADME/Tox profiling studies of new 1-aryl-5-(3-azidopropyl)indol-4-ones: Potential inhibitors of SARS CoV-2 main protease

Domínguez-Villa FX, Durán-Iturbide NA, Ávila-Zárraga JG.

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SARS coronavirus 2: from genome to infectome

Rastogi M, Pandey N, Shukla A, Singh SK.

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Carnosine to Combat Novel Coronavirus (nCoV): Molecular Docking and Modeling to Cocrystallized Host Angiotensin-Converting Enzyme 2 (ACE2) and Viral Spike Protein

Saadah LM, Deiab GIA, Al-Balas Q, Basheti IA.

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Repositioning of Ligands That Target the Spike Glycoprotein as Potential Drugs for SARS-CoV-2 in an In Silico Study

Ramírez-Salinas GL, Martínez-Archundia M, Correa-Basurto J, García-Machorro J.

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Detection of breastmilk antibodies targeting SARS-CoV-2 nucleocapsid, spike and receptor-binding-domain antigens

Favara DM, Ceron-Gutierrez ML, Carnell GW, Heeney JL, Corrie P, Doffinger R.

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D614G Spike Variant Does Not Alter IgG, IgM, or IgA Spike Seroassay Performance

Klumpp-Thomas C, Kalish H, Hicks J, Mehalko J, Drew M, Memoli MJ, Hall MD, Esposito D, Sadtler K.

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Conserved interactions required for inhibition of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Shitrit A, Zaidman D, Kalid O, Bloch I, Doron D, Yarnizky T, Buch I, Segev I, Ben-Zeev E, Segev E, Kobiler O.

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Biomolecular endotype factors involved in COVID-19 airway infectivity: A systematic review

Jain N, Varman R, Tarbox JA, Nguyen T.

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Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

Nomburg J, Meyerson M, DeCaprio JA.

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Characterization of Structural and Energetic Differences between Conformations of the SARS-CoV-2 Spike Protein

Moreira RA, Guzman HV, Boopathi S, Baker JL, Poma AB.

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Novel Small-Molecule Scaffolds as Candidates against the SARS Coronavirus 2 Main Protease: A Fragment-Guided in Silico Approach

Augustin TL, Hajbabaie R, Harper MT, Rahman T.

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Common determinants of severe Covid-19 infection are explicable by SARS-CoV-2 secreted glycoprotein interaction with the CD33-related Siglecs, Siglec-3 and Siglec-5/14

Murch SH.

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The influence of ABO blood groups on COVID-19 susceptibility and severity: A molecular hypothesis based on carbohydrate-carbohydrate interactions

Silva-Filho JC, Melo CGF, Oliveira JL.

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Targeting the SARS-CoV2 nucleocapsid protein for potential therapeutics using immuno-informatics and structure-based drug discovery techniques

Kwarteng A, Asiedu E, Sakyi SA, Asiedu SO.

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A Gapless, Unambiguous RNA Metagenome-Assembled Genome Sequence of a Unique SARS-CoV-2 Variant Encoding Spike S813I and ORF1a A859V Substitutions

Soliman MS, AbdelFattah M, Aman SMN, Ibrahim LM, Aziz RK.

Abstract:

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Combination of QSAR, molecular docking, molecular dynamic simulation and MM-PBSA: analogues of lopinavir and favipiravir as potential drug candidates against COVID-19

Rafi MO, Bhattacharje G, Al-Khafaji K, Taskin-Tok T, Alfasane MA, Das AK, Parvez MAK, Rahman MS.

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Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach

Maurya DK, Sharma D.

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Screening marine algae metabolites as high-affinity inhibitors of SARS-CoV-2 main protease (3CLpro): an in silico analysis to identify novel drug candidates to combat COVID-19 pandemic

Muteeb G, Alshoaibi A, Aatif M, Rehman MT, Qayyum MZ.

Abstract:

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High affinity of host human microRNAs to SARS-CoV-2 genome: An in silico analysis

Jafarinejad-Farsangi S, Jazi MM, Rostamzadeh F, Hadizadeh M.

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Supporting SARS-CoV-2 Papain-Like Protease Drug Discovery: In silico Methods and Benchmarking

Ibrahim TM, Ismail MI, Bauer MR, Bekhit AA, Boeckler FM.

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Extensive Thrombosis in a Severe COVID-19 Patient Despite Prophylactic Low Molecular Weight Heparin

Elkattawy S, Posimreddy S, Guragai N, Habib M, Shamoon F.

Abstract:

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Thermal and hydrodynamic properties of coronavirus at various temperature and pressure via molecular dynamics approach

Malekahmadi O, Zarei A, Botlani Esfahani MB, Hekmatifar M, Sabetvand R, Marjani A, Bach QV.

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DFT and Molecular Docking Study of Chloroquine Derivatives as Antiviral to Coronavirus COVID-19

Noureddine O, Issaoui N, Al-Dossary O.

Abstract:

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A multifactorial score including autophagy for prognosis and care of COVID-19 patients

Domdom MA, Brest P, Grosjean I, Roméo B, Landi MT, Gal J, Klionsky DJ, Hofman P, Mograbi B.

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Coevolutionary forces shaping the fitness of SARS-CoV-2 spike glycoprotein against human receptor ACE2

Priya P, Shanker A.

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Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CL(pro) and PL(pro)), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)

Mouffouk C, Mouffouk S, Mouffouk S, Hambaba L, Haba H.

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Aerosol inhalation delivery of triazavirin in mice: outlooks for advanced therapy against novel viral infections

Valiulin SV, Onischuk AA, Dubtsov SN, Baklanov AM, An'kov SV, Plokhotnichenko ME, Tolstikova TG, Dultseva GG, Rusinov VL, Charushin VN, Fomin VM.

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Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays

Mehalko J, Drew M, Snead K, Denson JP, Wall V, Taylor T, Sadtler K, Messing S, Gillette W, Esposito D.

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Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

Savastano A, Ibáñez de Opakua A, Rankovic M, Zweckstetter M.

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Exploring nature's bounty: identification of Withania somnifera as a promising source of therapeutic agents against COVID-19 by virtual screening and in silico evaluation

Srivastava A, Siddiqui S, Ahmad R, Mehrotra S, Ahmad B, Srivastava AN.

Abstract:

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Multiple epitope-based vaccine prediction against SARS-CoV-2 spike glycoprotein

Sirohi PR, Gupta J, Somvanshi P, Prajapati VK, Grover A.

Abstract:

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Protease inhibitors targeting the main protease and papain-like protease of coronaviruses

Capasso C, Nocentini A, Supuran CT.

Abstract:

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Molecular docking and simulation investigation: effect of beta-sesquiphellandrene with ionic integration on SARS-CoV2 and SFTS viruses

Joshi A, Sunil Krishnan G, Kaushik V.

Abstract:

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An Update on Molecular Diagnostics for COVID-19

Islam KU, Iqbal J.

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Computation screening and molecular docking of FDA approved viral protease inhibitors as a potential drug against COVID-19

Absalan A, Doroud D, Salehi-Vaziri M, Kaghazian H, Ahmadi N, Zali F, Pouriavali's MH, Mousavi-Nasab SD.

Abstract:

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Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tract

Galanopoulos M, Doukatas A, Gazouli M.

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New strategy for COVID-19 vaccination: targeting the receptor-binding domain of the SARS-CoV-2 spike protein

Wang J.

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Characteristics of viral specimens collected from asymptomatic and fatal cases of COVID-19

Gorzalski AJ, Hartley P, Laverdure C, Kerwin H, Tillett R, Verma S, Rossetto C, Morzunov S, Van Hooser S, Pandori MW.

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Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2's main protease

Mahdi M, Mótyán JA, Szojka ZI, Golda M, Miczi M, Tőzsér J.

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Molecular Basis of Cardiac and Vascular Injuries Associated With COVID-19

Hachim MY, Al Heialy S, Senok A, Hamid Q, Alsheikh-Ali A.

Abstract:

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In silico studies evidenced the role of structurally diverse plant secondary metabolites in reducing SARS-CoV-2 pathogenesis

Puttaswamy H, Gowtham HG, Ojha MD, Yadav A, Choudhir G, Raguraman V, Kongkham B, Selvaraju K, Shareef S, Gehlot P, Ahamed F, Chauhan L.

Abstract:

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Conserved Genomic Terminals of SARS-CoV-2 as Coevolving Functional Elements and Potential Therapeutic Targets

Chan AP, Choi Y, Schork NJ.

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Molecular investigation of adequate sources of mesenchymal stem cells for cell therapy of COVID-19-associated organ failure

Desterke C, Griscelli F, Imeri J, Marcoux P, Lemonnier T, Latsis T, Turhan AG, Bennaceur-Griscelli A.

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Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses

Simabuco FM, Tamura RE, Pavan ICB, Morale MG, Ventura AM.

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Zinc and SARS‑CoV‑2: A molecular modeling study of Zn interactions with RNA‑dependent RNA‑polymerase and 3C‑like proteinase enzymes

Pormohammad A, Monych NK, Turner RJ.

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COVID-19 Genome Surveillance at International Airport Quarantine Stations in Japan

Sekizuka T, Itokawa K, Yatsu K, Tanaka R, Hashino M, Kawano-Sugaya T, Ohnishi M, Wakita T, Kuroda M; COVID-19 Genomic Surveillance Network in Japanese Airport Quarantine.

Abstract:

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Mosaic RBD nanoparticles elicit neutralizing antibodies against SARS-CoV-2 and zoonotic coronaviruses

Cohen AA, Gnanapragasam PNP, Lee YE, Hoffman PR, Ou S, Kakutani LM, Keeffe JR, Barnes CO, Nussenzweig MC, Bjorkman PJ.

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Replicating bacterium-vectored vaccine expressing SARS-CoV-2 Membrane and Nucleocapsid proteins protects against severe COVID-19 disease in hamsters

Jia Q, Bielefeldt-Ohmann H, Maison R, Masleša-Galić S, Bowen R, Horwitz MA.

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First clinical study using HCV protease inhibitor danoprevir to treat COVID-19 patients

Chen H, Zhang Z, Wang L, Huang Z, Gong F, Li X, Chen Y, Wu JJ.

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Biomimetic Nanoparticles Potentiate the Anti-Inflammatory Properties of Dexamethasone and Reduce the Cytokine Storm Syndrome: An Additional Weapon against COVID-19?

Molinaro R, Pasto A, Taraballi F, Giordano F, Azzi JA, Tasciotti E, Corbo C.

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Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate

Sun W, Leist SR, McCroskery S, Liu Y, Slamanig S, Oliva J, Amanat F, Schäfer A, Dinnon KH 3rd, García-Sastre A, Krammer F, Baric RS, Palese P.

Abstract:

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SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells

Suzuki YJ, Nikolaienko SI, Dibrova VA, Dibrova YV, Vasylyk VM, Novikov MY, Shults NV, Gychka SG.

Abstract:

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Down's syndrome and COVID-19: risk or protection factor against infection? A molecular and genetic approach

Altable M, de la Serna JM.

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Mouse Genome Database (MGD): Knowledgebase for mouse-human comparative biology

Blake JA, Baldarelli R, Kadin JA, Richardson JE, Smith CL, Bult CJ; Mouse Genome Database Group.

Abstract:

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Catechin Derivatives as Inhibitor of COVID-19 Main Protease (Mpro): Molecular Docking studies unveils an opportunity against CORONA

Arif MN.

Abstract:

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Molecular targets and system biology approaches for drug repurposing against SARS-CoV-2

Singh RK, Yadav BS, Mohapatra TM.

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Virtual screening of anti-HIV1 compounds against SARS-CoV-2: machine learning modeling, chemoinformatics and molecular dynamics simulation based analysis

Nand M, Maiti P, Joshi T, Chandra S, Pande V, Kuniyal JC, Ramakrishnan MA.

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Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2

Popa A, Genger JW, Nicholson MD, Penz T, Schmid D, Aberle SW, Agerer B, Lercher A, Endler L, Colaço H, Smyth M, Schuster M, Grau ML, Martínez-Jiménez F, Pich O, Borena W, Pawelka E, Keszei Z, Senekowitsch M, Laine J, Aberle JH, Redlberger-Fritz M, Karolyi M, Zoufaly A, Maritschnik S, Borkovec M, Hufnagl P, Nairz M, Weiss G, Wolfinger MT, von Laer D, Superti-Furga G, Lopez-Bigas N, Puchhammer-Stöckl E, Allerberger F, Michor F, Bock C, Bergthaler A.

Abstract:

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The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing assembly of virus-like particles

Boson B, Legros V, Zhou B, Siret E, Mathieu C, Cosset FL, Lavillette D, Denolly S.

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Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a

Joonlasak K, Batty EM, Kochakarn T, Panthan B, Kümpornsin K, Jiaranai P, Wangwiwatsin A, Huang A, Kotanan N, Jaru-Ampornpan P, Manasatienkij W, Watthanachockchai T, Rakmanee K, Jones AR, Fernandez S, Sensorn I, Sungkanuparph S, Pasomsub E, Klungthong C, Chookajorn T, Chantratita W.

Abstract:

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Evaluating SARS-CoV-2 spike and nucleocapsid proteins as targets for antibody detection in severe and mild COVID-19 cases using a Luminex bead-based assay

Mariën J, Ceulemans A, Michiels J, Heyndrickx L, Kerkhof K, Foque N, Widdowson MA, Mortgat L, Duysburgh E, Desombere I, Jansens H, Van Esbroeck M, Ariën KK.

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Theoretical Design of Functionalized Gold Nanoparticles as Antiviral Agents against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Mehranfar A, Izadyar M.

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Targeting SARS-CoV-2 main protease: structure based virtual screening, in silico ADMET studies and molecular dynamics simulation for identification of potential inhibitors

Uniyal A, Mahapatra MK, Tiwari V, Sandhir R, Kumar R.

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Evaluation on the use of Nanopore sequencing for direct characterization of coronaviruses from respiratory specimens, and a study on emerging missense mutations in partial RdRP gene of SARS-CoV-2

Chan WS, Au CH, Lam HY, Wang CLN, Ho DN, Lam YM, Chu DKW, Poon LLM, Chan TL, Zee JS, Ma ESK, Tang BSF.

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In silico screening predicts common cold drug Dextromethorphan along with Prednisolone and Dexamethasone can be effective against novel Coronavirus disease (COVID-19)

Sarkar I, Sen A.

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Designing Spike protein (S-Protein) based multi-epitope peptide vaccine against SARS COVID-19 by immunoinformatics

Singh H, Jakhar R, Sehrawat N.

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Molecular dynamics performance for coronavirus simulation by C, N, O, and S atoms implementation dreiding force field: drug delivery atomic interaction in contact with metallic Fe, Al, and steel

Karimipour A, Amini A, Nouri M, D'Orazio A, Sabetvand R, Hekmatifar M, Marjani A, Bach QV.

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Molecular Interaction Analysis of Sulawesi Propolis Compounds with SARS-CoV-2 Main Protease as Preliminary Study for COVID-19 Drug Discovery

Sahlan M, Irdiani R, Flamandita D, Aditama R, Alfarraj S, Javed Ansari M, Cahya Khayrani A, Kartika Pratami D, Lischer K.

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Functional importance of the D614G mutation in the SARS-CoV-2 spike protein

Jackson CB, Zhang L, Farzan M, Choe H.

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The Human Leukocyte Antigen Class II Immunopeptidome of the SARS-CoV-2 Spike Glycoprotein

Knierman MD, Lannan MB, Spindler LJ, McMillian CL, Konrad RJ, Siegel RW.

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Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2, Colombia

Laiton-Donato K, Villabona-Arenas CJ, Usme-Ciro JA, Franco-Muñoz C, Álvarez-Díaz DA, Villabona-Arenas LS, Echeverría-Londoño S, Cucunubá ZM, Franco-Sierra ND, Flórez AC, Ferro C, Ajami NJ, Walteros DM, Prieto F, Durán CA, Ospina-Martínez ML, Mercado-Reyes M.

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Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients

Mostafa HH, Fissel JA, Fanelli B, Bergman Y, Gniazdowski V, Dadlani M, Carroll KC, Colwell RR, Simner PJ.

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Target-Centered Drug Repurposing Predictions of Human Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Protease Serine Subtype 2 (TMPRSS2) Interacting Approved Drugs for Coronavirus Disease 2019 (COVID-19) Treatment through a Drug-Target Interaction Deep Learning Model

Choi Y, Shin B, Kang K, Park S, Beck BR.

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Evaluation of acridinedione analogs as potential SARS-CoV-2 main protease inhibitors and their comparison with repurposed anti-viral drugs

Bhardwaj VK, Singh R, Das P, Purohit R.

Abstract:

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[Morphological and molecular changes in the lung of COVID-19 patients]

Augustin M, Hallek M, Nitschmann S.

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Activity of phytochemical constituents of Curcuma longa (turmeric) and Andrographis paniculata against coronavirus (COVID-19): an in silico approach

Rajagopal K, Varakumar P, Baliwada A, Byran G.

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Virtual screening and molecular simulation study of natural products database for lead identification of novel coronavirus main protease inhibitors

Tripathi N, Goel B, Bhardwaj N, Sahu B, Kumar H, Jain SK.

Abstract:

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Structure-based identification of potential SARS-CoV-2 main protease inhibitors

Khan S, Fakhar Z, Hussain A, Ahmad A, Jairajpuri DS, Alajmi MF, Hassan MI.

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Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19

Kuo TY, Lin MY, Coffman RL, Campbell JD, Traquina P, Lin YJ, Liu LT, Cheng J, Wu YC, Wu CC, Tang WH, Huang CG, Tsao KC, Chen C.

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Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site

Lee J, Worrall LJ, Vuckovic M, Rosell FI, Gentile F, Ton AT, Caveney NA, Ban F, Cherkasov A, Paetzel M, Strynadka NCJ.

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The IMEx coronavirus interactome: an evolving map of Coronaviridae-host molecular interactions

Perfetto L, Pastrello C, Del-Toro N, Duesbury M, Iannuccelli M, Kotlyar M, Licata L, Meldal B, Panneerselvam K, Panni S, Rahimzadeh N, Ricard-Blum S, Salwinski L, Shrivastava A, Cesareni G, Pellegrini M, Orchard S, Jurisica I, Hermjakob H, Porras P.

Abstract:

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Clinical and molecular characterization of COVID-19 hospitalized patients

Benetti E, Giliberti A, Emiliozzi A, Valentino F, Bergantini L, Fallerini C, Anedda F, Amitrano S, Conticini E, Tita R, d'Alessandro M, Fava F, Marcantonio S, Baldassarri M, Bruttini M, Mazzei MA, Montagnani F, Mandalà M, Bargagli E, Furini S; GEN-COVID Multicenter Study, Renieri A, Mari F.

Abstract:

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Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19

Baby K, Maity S, Mehta CH, Suresh A, Nayak UY, Nayak Y.

Abstract:

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Potential SARS-CoV-2 protease Mpro inhibitors: Repurposing FDA-approved drugs

Kouznetsova VL, Huang DZ, Tsigelny IF.

Abstract:

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Furin Protease: From SARS CoV-2 to Anthrax, Diabetes, and Hypertension

Fitzgerald K.

Abstract:

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NETosis: Molecular Mechanisms, Role in Physiology and Pathology

Vorobjeva NV, Chernyak BV.

Abstract:

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Association of SARS-CoV-2 genomic load trends with clinical status in COVID-19: A retrospective analysis from an academic hospital center in New York City

Zacharioudakis IM, Zervou FN, Prasad PJ, Shao Y, Basu A, Inglima K, Weisenberg SA, Aguero-Rosenfeld ME.

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Molecular docking studies, molecular dynamics and ADME/tox reveal therapeutic potentials of STOCK1N-69160 against papain-like protease of SARS-CoV-2

Elekofehinti OO, Iwaloye O, Josiah SS, Lawal AO, Akinjiyan MO, Ariyo EO.

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Clinical performances of three fully automated anti-SARS-CoV-2 immunoassays targeting the nucleocapsid or spike proteins

Favresse J, Cadrobbi J, Eucher C, Elsen M, Laffineur K, Dogné JM, Douxfils J.

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Natural Compounds as Inhibitors of SARS-CoV-2 Main Protease (3CLpro): A Molecular Docking and Simulation Approach to Combat COVID-19

Rehman MT, AlAjmi MF, Hussain A.

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Determination of potential inhibitors based on isatin derivatives against SARS-CoV-2 main protease (m(pro)): a molecular docking, molecular dynamics and structure-activity relationship studies

Badavath VN, Kumar A, Samanta PK, Maji S, Das A, Blum G, Jha A, Sen A.

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Inhibitory potential of repurposed drugs against the SARS-CoV-2 main protease: a computational-aided approach

Fadaka AO, Aruleba RT, Sibuyi NRS, Klein A, Madiehe AM, Meyer M.

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Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2

Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Griffiths A, Abraham J.

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Tuning Proton Transfer Thermodynamics in SARS-Cov-2 Main Protease: Implications for Catalysis and Inhibitor Design

Zanetti-Polzi L, Smith M, Chipot C, Gumbart JC, Lynch DL, Pavlova A, Smith JC, Daidone I.

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A multiple peptides vaccine against COVID-19 designed from the nucleocapsid phosphoprotein (N) and Spike Glycoprotein (S) via the immunoinformatics approach

Abd Albagi SO, Al-Nour MY, Elhag M, Tageldein Idris Abdelihalim A, Musa Haroun E, Adam Essa ME, Abubaker M, Deka H, Ghosh A, Hassan MA.

Abstract:

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Mutations in the SARS-CoV-2 Spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization

Shah M, Ahmad B, Choi S, Goo Woo H.

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In silico and In vitro Studies Reveal Complement System Drives Coagulation Cascade in SARS-CoV-2 Pathogenesis

Tiwari R, Mishra AR, Mikaeloff F, Gupta S, Mirazimi A, Byrareddy SN, Neogi U, Nayak D.

Abstract:

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Plant-derived silica nanoparticles and composites for biosensors, bioimaging, drug delivery and supercapacitors: a review

Prabha S, Durgalakshmi D, Rajendran S, Lichtfouse E.

Abstract:

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Synthesis of novel coumarin analogues: Investigation of molecular docking interaction of SARS-CoV-2 proteins with natural and synthetic coumarin analogues and their pharmacokinetics studies

Sathish Kumar C, El-Sheikh MA, Alfarhan AH, SurendraKumar R, Idhayadhulla A.

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Evolution patterns of SARS-CoV-2: Snapshot on its genome variants

Giovanetti M, Benedetti F, Campisi G, Ciccozzi A, Fabris S, Ceccarelli G, Tambone V, Caruso A, Angeletti S, Zella D, Ciccozzi M.

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Immunodominant regions prediction of nucleocapsid protein for SARS-CoV-2 early diagnosis: a bioinformatics and immunoinformatics study

Dai Y, Chen H, Zhuang S, Feng X, Fang Y, Tang H, Dai R, Tang L, Liu J, Ma T, Zhong G.

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Identification of a New Potential SARS-COV-2 RNA-Dependent RNA Polymerase Inhibitor via Combining Fragment-Based Drug Design, Docking, Molecular Dynamics, and MM-PBSA Calculations

El Hassab MA, Shoun AA, Al-Rashood ST, Al-Warhi T, Eldehna WM.

Abstract:

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Non-SARS-CoV-2 genome sequences identified in clinical samples from COVID-19 infected patients: Evidence for co-infections

Abouelkhair MA.

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Epitope-based chimeric peptide vaccine design against S, M and E proteins of SARS-CoV-2, the etiologic agent of COVID-19 pandemic: an in silico approach

Rahman MS, Hoque MN, Islam MR, Akter S, Rubayet Ul Alam ASM, Siddique MA, Saha O, Rahaman MM, Sultana M, Crandall KA, Hossain MA.

Abstract:

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Long-Term Impact of Social Isolation and Molecular Underpinnings

Arzate-Mejía RG, Lottenbach Z, Schindler V, Jawaid A, Mansuy IM.

Abstract:

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Predicting the Animal Susceptibility and Therapeutic Drugs to SARS-CoV-2 Based on Spike Glycoprotein Combined With ACE2

Shen M, Liu C, Xu R, Ruan Z, Zhao S, Zhang H, Wang W, Huang X, Yang L, Tang Y, Yang T, Jia X.

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CoVaccine HTâ„¢ Adjuvant Potentiates Robust Immune Responses to Recombinant SARS-CoV-2 Spike S1 Immunization

Haun BK, Lai CY, Williams CA, Wong TAS, Lieberman MM, Pessaint L, Andersen H, Lehrer AT.

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Immunoinformatic Analysis of SARS-CoV-2 Nucleocapsid Protein and Identification of COVID-19 Vaccine Targets

Oliveira SC, de Magalhães MTQ, Homan EJ.

Abstract:

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Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals

Brochot E, Demey B, Touzé A, Belouzard S, Dubuisson J, Schmit JL, Duverlie G, Francois C, Castelain S, Helle F.

Abstract:

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Emerging Molecular Prospective of SARS-CoV-2: Feasible Nanotechnology Based Detection and Inhibition

Patra S, Kerry RG, Maurya GK, Panigrahi B, Kumari S, Rout JR.

Abstract:

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Designing of Nucleocapsid Protein Based Novel Multi-epitope Vaccine Against SARS-COV-2 Using Immunoinformatics Approach

Kumar J, Qureshi R, Sagurthi SR, Qureshi IA.

Abstract:

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Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2

Wei S, Duan S, Liu X, Wang H, Ding S, Chen Y, Xie J, Tian J, Yu N, Ge P, Zhang X, Chen X, Li Y, Meng Q.

Abstract:

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Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors

Amin SA, Banerjee S, Ghosh K, Gayen S, Jha T.

Abstract:

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Network pharmacology, molecular docking integrated surface plasmon resonance technology reveals the mechanism of Toujie Quwen Granules against coronavirus disease 2019 pneumonia

Ye M, Luo G, Ye D, She M, Sun N, Lu YJ, Zheng J.

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Management of bacteriological specimens of patients suffering from coronavirus disease 2019 (COVID-19)

Hogardt M, Besier S, Vorbeck L, Göttig S, Wichelhaus TA, Villinger D, Hack D, Sommer J, Ilievski V, Kempf VAJ.

Abstract:

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Revealing the Inhibition Mechanism of RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Remdesivir and Nucleotide Analogues: A Molecular Dynamics Simulation Study

Wakchaure PD, Ghosh S, Ganguly B.

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Spike Glycoprotein-Mediated Entry of SARS Coronaviruses

Wang L, Xiang Y.

Abstract:

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Coronavirus disease 2019 and asthma, allergic rhinitis: molecular mechanisms and host-environmental interactions

Wakabayashi M, Pawankar R, Narazaki H, Ueda T, Itabashi T.

Abstract:

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Low molecular weight heparin in COVID-19 patients prevents delirium and shortens hospitalization

D'Ardes D, Carrarini C, Russo M, Dono F, Speranza R, Digiovanni A, Martinotti G, Di Iorio A, Onofrj M, Cipollone F, Bonanni L.

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Development and evaluation of a serological test for diagnosis of COVID-19 with selected recombinant spike proteins

Zhang P, Gao Q, Wang T, Ke Y, Mo F, Jia R, Liu W, Liu L, Zheng S, Liu Y, Li L, Wang Y, Xu L, Hao K, Min W, Liu X, Yang R, Li S, Lin C, Zhao Y.

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Identification of saquinavir as a potent inhibitor of dimeric SARS-CoV2 main protease through MM/GBSA

Bello M, Martínez-Muñoz A, Balbuena-Rebolledo I.

Abstract:

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Peptide modelling and screening against human ACE2 and spike glycoprotein RBD of SARS-CoV-2

Rathod SB, Prajapati PB, Punjabi LB, Prajapati KN, Chauhan N, Mansuri MF.

Abstract:

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Molecular targeting of vulnerable RNA sequences in SARS CoV-2: identifying clinical feasibility

Ian Gallicano G, Casey JL, Fu J, Mahapatra S.

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Identification of a repurposed drug as an inhibitor of Spike protein of human coronavirus SARS-CoV-2 by computational methods

Unni S, Aouti S, Thiyagarajan S, Padmanabhan B.

Abstract:

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Analysis of genomic distributions of SARS-CoV-2 reveals a dominant strain type with strong allelic associations

Yang HC, Chen CH, Wang JH, Liao HC, Yang CT, Chen CW, Lin YC, Kao CH, Lu MJ, Liao JC.

Abstract:

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Identification of natural inhibitors against prime targets of SARS-CoV-2 using molecular docking, molecular dynamics simulation and MM-PBSA approaches

Sharma A, Vora J, Patel D, Sinha S, Jha PC, Shrivastava N.

Abstract:

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Analysis of the potential impact of genomic variants in global SARS-CoV-2 genomes on molecular diagnostic assays

Jain A, Rophina M, Mahajan S, Krishnan BB, Sharma M, Mandal S, Fernandez T, Sultanji S, Jolly B, Mathew S, Sivasubbu S, Scaria V.

Abstract:

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Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein

Calcagnile M, Forgez P, Iannelli A, Bucci C, Alifano M, Alifano P.

Abstract:

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In silico analysis of selected alkaloids against main protease (M(pro)) of SARS-CoV-2

Garg S, Roy A.

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Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 in lung epithelium

Schuler BA, Habermann AC, Plosa EJ, Taylor CJ, Jetter C, Negretti NM, Kapp ME, Benjamin JT, Gulleman P, Nichols DS, Braunstein LZ, Hackett A, Koval M, Guttentag SH, Blackwell TS, Webber SA, Banovich NE, Kropski JA, Sucre JMS.

Abstract:

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Reprofiling of approved drugs against SARS-CoV-2 main protease: an in-silico study

Kumar P, Bhardwaj T, Kumar A, Gehi BR, Kapuganti SK, Garg N, Nath G, Giri R.

Abstract:

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In-silico drug repurposing for targeting SARS-CoV-2 main protease (M(pro))

Sharma S, Deep S.

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A Genome Epidemiological Study of SARS-CoV-2 Introduction into Japan

Sekizuka T, Itokawa K, Hashino M, Kawano-Sugaya T, Tanaka R, Yatsu K, Ohnishi A, Goto K, Tsukagoshi H, Ehara H, Sadamasu K, Taira M, Shibata S, Nomoto R, Hiroi S, Toho M, Shimada T, Matsui T, Sunagawa T, Kamiya H, Yahata Y, Yamagishi T, Suzuki M, Wakita T, Kuroda M.

Abstract:

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Molecular basis for drug repurposing to study the interface of the S protein in SARS-CoV-2 and human ACE2 through docking, characterization, and molecular dynamics for natural drug candidates

Alazmi M, Motwalli O.

Abstract:

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Errors in Tracing Coronavirus SARS-CoV-2 Transmission Using a Maximum Likelihood Tree. Comment on "A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis"

Forster P, Forster L.

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Authors' Reply to: Errors in Tracing Coronavirus SARS-CoV-2 Transmission Using a Maximum Likelihood Tree. Comment on "A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis"

Mavian C, Marini S, Prosperi M, Salemi M.

Abstract:

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Context contribution to the intermolecular recognition of human ACE2-derived peptides by SARS-CoV-2 spike protein: implications for improving the peptide affinity but not altering the peptide specificity by optimizing indirect readout

Zhou P, Wang H, Chen Z, Liu Q.

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Interactive Molecular Dynamics in Virtual Reality Is an Effective Tool for Flexible Substrate and Inhibitor Docking to the SARS-CoV-2 Main Protease

Deeks HM, Walters RK, Barnoud J, Glowacki DR, Mulholland AJ.

Abstract:

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The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition

Hattori T, Koide A, Panchenko T, Romero LA, Teng KW, Tada T, Landau NR, Koide S.

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Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus

Steenwyk JL, Mead ME, de Castro PA, Valero C, Damasio A, Dos Santos RAC, Labella AL, Li Y, Knowles SL, Raja HA, Oberlies NH, Zhou X, Cornely OA, Fuchs F, Koehler P, Goldman GH, Rokas A.

Abstract:

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Gold Nanorod Assisted Enhanced Plasmonic Detection Scheme of COVID-19 SARS-CoV-2 Spike Protein

Das CM, Guo Y, Yang G, Kang L, Xu G, Ho HP, Yong KT.

Abstract:

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Repurposed Drugs, Molecular Vaccines, Immune-Modulators, and Nanotherapeutics to Treat and Prevent COVID-19 Associated with SARS-CoV-2, a Deadly Nanovector

Dube T, Ghosh A, Mishra J, Kompella UB, Panda JJ.

Abstract:

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Tinker-HP : Accelerating Molecular Dynamics Simulations of Large Complex Systems with Advanced Point Dipole Polarizable Force Fields using GPUs and Multi-GPUs systems

Adjoua O, Lagardère L, Jolly LH, Durocher A, Very T, Dupays I, Wang Z, Inizan TJ, Célerse F, Ren P, Ponder JW, Piquemal JP.

Abstract:

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A Hydrophobic-Interaction-Based Mechanism Triggers Docking between the SARS-CoV-2 Spike and Angiotensin-Converting Enzyme 2

Li J, Ma X, Guo S, Hou C, Shi L, Zhang H, Zheng B, Liao C, Yang L, Ye L, He X.

Abstract:

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Drugs Repurposing Using QSAR, Docking and Molecular Dynamics for Possible Inhibitors of the SARS-CoV-2 M(pro) Protease

Tejera E, Munteanu CR, López-Cortés A, Cabrera-Andrade A, Pérez-Castillo Y.

Abstract:

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Serological antibody testing in the COVID-19 pandemic: their molecular basis and applications

Jiang JC, Zhang Y.

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Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations

Laamarti M, Alouane T, Kartti S, Chemao-Elfihri MW, Hakmi M, Essabbar A, Laamarti M, Hlali H, Bendani H, Boumajdi N, Benhrif O, Allam L, El Hafidi N, El Jaoudi R, Allali I, Marchoudi N, Fekkak J, Benrahma H, Nejjari C, Amzazi S, Belyamani L, Ibrahimi A.

Abstract:

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Static all-atom energetic mappings of the SARS-Cov-2 spike protein and dynamic stability analysis of "Up" versus "Down" protomer states

Peters MH, Bastidas O, Kokron DS, Henze CE.

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Step toward repurposing drug discovery for COVID-19 therapeutics through in silico approach

Marak BN, Dowarah J, Khiangte L, Singh VP.

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Comparative sensitivity of different respiratory specimen types for molecular diagnosis and monitoring of SARS-CoV-2 shedding in COVID-19 patients

Yang Y, Yang M, Yuan J, Wang F, Wang Z, Li J, Zhang M, Xing L, Wei J, Peng L, Wong G, Zheng H, Wu W, Shen C, Liao M, Feng K, Li J, Yang Q, Zhao J, Liu L, Liu Y.

Abstract:

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Impact of Gastrointestinal Symptoms in COVID-19: a Molecular Approach

Sonkar C, Kashyap D, Varshney N, Baral B, Jha HC.

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Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach

Indu P, Rameshkumar MR, Arunagirinathan N, Al-Dhabi NA, Valan Arasu M, Ignacimuthu S.

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Deletion in the C-terminal region of the envelope glycoprotein in some of the Indian SARS-CoV-2 genome

Kumar BK, Rohit A, Prithvisagar KS, Rai P, Karunasagar I, Karunasagar I.

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Network pharmacology-based study of the molecular mechanisms of Qixuekang in treating COVID-19 during the recovery period

Tian J, Sun D, Xie Y, Liu K, Ma Y.

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Identification of a dominant CD8(+) CTL epitope in the SARS-associated coronavirus 2 spike protein

Muraoka D, Situo D, Sawada SI, Akiyoshi K, Harada N, Ikeda H.

Abstract:

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Multi-epitope vaccine against SARS-CoV-2 applying immunoinformatics and molecular dynamics simulation approaches

Jyotisha, Singh S, Qureshi IA.

Abstract:

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Biosafety Guidelines for COVID-19 Specimens in Biobanks

Parichehreh-Dizaji S, Haghpanah V.

Abstract:

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Comparative analysis of nanomechanical features of coronavirus spike proteins and correlation with lethality and infection rate

Hu Y, Buehler MJ.

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Genomic exploration light on multiple origin with potential parsimony-informative sites of the severe acute respiratory syndrome coronavirus 2 in Bangladesh

Saha O, Hossain MS, Rahaman MM.

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The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene

Kim S, Lee JH, Lee S, Shim S, Nguyen TT, Hwang J, Kim H, Choi YO, Hong J, Bae S, Jhun H, Yum H, Lee Y, Chan ED, Yu L, Azam T, Kim YD, Yeom SC, Yoo KH, Kang LW, Shin KC, Kim S.

Abstract:

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[Sars-CoV-2 genomic and phylodynamic analyses]

Elie B, Alizon S.

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Computational drug re-purposing targeting the spike glycoprotein of SARS-CoV-2 as an effective strategy to neutralize COVID-19

Toor HG, Banerjee DI, Lipsa Rath S, Darji SA.

Abstract:

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Three Proposals to Optimise the Eastern Cooperative Oncology Group and Karnofsky Scales in the Molecular and COVID-19 Era

Ponzetti A, Laface R, Milanesi E, Ciuffreda L.

Abstract:

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Coevolution, Dynamics and Allostery Conspire in Shaping Cooperative Binding and Signal Transmission of the SARS-CoV-2 Spike Protein with Human Angiotensin-Converting Enzyme 2

Verkhivker G.

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Significantly decreased mortality in a large cohort of COVID-19 patients transfused early with convalescent plasma containing high titer anti-SARS-CoV-2 spike protein IgG

Salazar E, Christensen PA, Graviss EA, Nguyen DT, Castillo B, Chen J, Lopez BV, Eagar TN, Yi X, Zhao P, Rogers J, Shehabeldin A, Joseph D, Masud F, Leveque C, Olsen RJ, Bernard DW, Gollihar J, Musser JM.

Abstract:

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Fast-track ruling in/out SARS-CoV-2 infection with rapid 0/1.5 h molecular test in patients with acute coronary syndromes

Spaccarotella C, Migliarino S, Mongiardo A, Curcio A, de Rosa S, Corcione N, Quirino A, Barreca GS, Giancotti A, Peronace C, Marascio N, Matera G, Indolfi C.

Abstract:

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Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein

Tandon R, Mitra D, Sharma P, McCandless MG, Stray SJ, Bates JT, Marshall GD.

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Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

Malladi SK, Singh R, Pandey S, Gayathri S, Kanjo K, Ahmed S, Khan MS, Kalita P, Girish N, Upadhyaya A, Reddy P, Pramanick I, Bhasin M, Mani S, Bhattacharyya S, Joseph J, Thankamani K, Raj VS, Dutta S, Singh R, Nadig G, Varadarajan R.

Abstract:

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Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?

Delorme-Axford E, Klionsky DJ.

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Molecular screening of antimalarial, antiviral, anti-inflammatory and HIV protease inhibitors against spike glycoprotein of coronavirus

Prashantha CN, Gouthami K, Lavanya L, Bhavanam S, Jakhar A, Shakthiraju RG, Suraj V, Sahana KV, Sujana HS, Guruprasad NM, Ramachandra R.

Abstract:

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Identification of potential COVID-19 main protease inhibitors using structure-based pharmacophore approach, molecular docking and repurposing studies

Daoud S, Alabed SJ, Dahabiyeh LA.

Abstract:

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Optimized and scalable synthesis of magnetic nanoparticles for RNA extraction in response to developing countries' needs in the detection and control of SARS-CoV-2

Chacón-Torres JC, Reinoso C, Navas-León DG, Briceño S, González G.

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SARS-CoV-2 Cysteine-like Protease Antibodies Can Be Detected in Serum and Saliva of COVID-19-Seropositive Individuals

Martínez-Fleta P, Alfranca A, González-Álvaro I, Casasnovas JM, Fernández-Soto D, Esteso G, Cáceres-Martell Y, Gardeta S, López-Sanz C, Prat S, Mateu-Albero T, Gabrie L, López-Granados E, Sánchez-Madrid F, Reyburn HT, Rodríguez Frade JM, Valés-Gómez M.

Abstract:

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In Silico Antibody Mutagenesis for Optimizing Its Binding to Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2

Luan B, Huynh T.

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First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region

Kouriba B, Dürr A, Rehn A, Sangaré AK, Traoré BY, Bestehorn-Willmann MS, Ouedraogo J, Heitzer A, Sogodogo E, Maiga A, Walter MC, Zimmermann F, Wölfel R, Antwerpen MH.

Abstract:

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Epitope-Based Immunoinformatics Approach on Nucleocapsid Protein of Severe Acute Respiratory Syndrome-Coronavirus-2

Rakib A, Sami SA, Islam MA, Ahmed S, Faiz FB, Khanam BH, Marma KKS, Rahman M, Uddin MMN, Nainu F, Emran TB, Simal-Gandara J.

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Intrahost non-synonymous diversity at a neutralising antibody epitope of SARS-CoV-2 spike protein N-terminal domain

Ip JD, Kok KH, Chan WM, Wing-Ho Chu A, Wu WL, Chik-Yan Yip C, To WK, Tak-Yin Tsang O, Leung WS, Shiu-Hong Chik T, Chan KH, Fan-Ngai Hung I, Yuen KY, Kai-Wang To K.

Abstract:

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Identification of natural inhibitors against Mpro of SARS-CoV-2 by molecular docking, molecular dynamics simulation, and MM/PBSA methods

Sharma P, Joshi T, Mathpal S, Joshi T, Pundir H, Chandra S, Tamta S.

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The Role of Molecular Chaperones in Virus Infection and Implications for Understanding and Treating COVID-19

Paladino L, Vitale AM, Caruso Bavisotto C, Conway de Macario E, Cappello F, Macario AJL, Gammazza AM.

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A needle in the haystack? Assessing the significance of envelope (E) gene-negative, nucleocapsid (N2) gene-positive SARS-CoV-2 detection by the Cepheid Xpert Xpress SARS-COV-2 assay

Khoshchehreh M, Wald-Dickler N, Holtom P, Butler-Wu SM.

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HLA and AB0 Polymorphisms May Influence SARS-CoV-2 Infection and COVID-19 Severity

Amoroso A, Magistroni P, Vespasiano F, Bella A, Bellino S, Puoti F, Alizzi S, Vaisitti T, Boros S, Grossi PA, Trapani S, Lombardini L, Pezzotti P, Deaglio S, Brusaferro S, Cardillo M; Italian network of Regional Transplant Coordinating Centers (*).

Abstract:

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A comprehensive review on promising anti-viral therapeutic candidates identified against main protease from SARS-CoV-2 through various computational methods

Singh E, Khan RJ, Jha RK, Amera GM, Jain M, Singh RP, Muthukumaran J, Singh AK.

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SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study

Hurst JH, Heston SM, Chambers HN, Cunningham HM, Price MJ, Suarez L, Crew CG, Bose S, Aquino JN, Carr ST, Griffin SM, Smith SH, Jenkins K, Pfeiffer TS, Rodriguez J, DeMarco CT, De Naeyer NA, Gurley TC, Louzao R, Zhao C, Cunningham CK, Steinbach WJ, Denny TN, Lugo DJ, Moody MA, Permar SR, Rotta AT, Turner NA, Walter EB, Woods CW, Kelly MS.

Abstract:

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Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID-19

Xia QD, Xun Y, Lu JL, Lu YC, Yang YY, Zhou P, Hu J, Li C, Wang SG.

Abstract:

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Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage

Chen YM, Zheng Y, Yu Y, Wang Y, Huang Q, Qian F, Sun L, Song ZG, Chen Z, Feng J, An Y, Yang J, Su Z, Sun S, Dai F, Chen Q, Lu Q, Li P, Ling Y, Yang Z, Tang H, Shi L, Jin L, Holmes EC, Ding C, Zhu TY, Zhang YZ.

Abstract:

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Targeting the initiation and termination codons of SARS-CoV-2 spike protein as possible therapy against COVID-19: the role of novel harpagide 5-O-β-D-glucopyranoside from Clerodendrum volubile P Beauv. (Labiatae)

Erukainure OL, Atolani O, Muhammad A, Katsayal SB, Ebhuoma OO, Ibeji CU, Mesaik MA.

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Targeting SARS-CoV-2 nucleocapsid oligomerization: Insights from molecular docking and molecular dynamics simulations

Ahamad S, Gupta D, Kumar V.

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Computer aided identification of potential SARS CoV-2 main protease inhibitors from diterpenoids and biflavonoids of Torreya nucifera leaves

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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DFT and docking studies of designed conjugates of noscapines & repurposing drugs: promising inhibitors of main protease of SARS-CoV-2 and falcipan-2

Kumar A, Kumar D, Kumar R, Singh P, Chandra R, Kumari K.

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Oral vesiculobullous lesions as an early sign of COVID-19: immunohistochemical detection of SARS-CoV-2 spike protein

Soares CD, Mosqueda-Taylor A, de Carvalho MGF, de Almeida OP.

Abstract:

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Retrospective in silico HLA predictions from COVID-19 patients reveal alleles associated with disease prognosis

Warren RL, Birol I.

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SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Kelly JN, Fan X, Hoffmann B, Steiner S, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson M, Keller M, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M.

Abstract:

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Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein

Casalino L, Gaieb Z, Goldsmith JA, Hjorth CK, Dommer AC, Harbison AM, Fogarty CA, Barros EP, Taylor BC, McLellan JS, Fadda E, Amaro RE.

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Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

Haniff HS, Tong Y, Liu X, Chen JL, Suresh BM, Andrews RJ, Peterson JM, O'Leary CA, Benhamou RI, Moss WN, Disney MD.

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Fighting COVID-19 Using Molecular Dynamics Simulations

Arantes PR, Saha A, Palermo G.

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Full genome viral sequences inform patterns of SARS-CoV-2 spread into and within Israel

Miller D, Martin MA, Harel N, Tirosh O, Kustin T, Meir M, Sorek N, Gefen-Halevi S, Amit S, Vorontsov O, Shaag A, Wolf D, Peretz A, Shemer-Avni Y, Roif-Kaminsky D, Kopelman NM, Huppert A, Koelle K, Stern A.

Abstract:

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Necessity for detection of SARS-CoV-2 RNA in multiple types of specimens for the discharge of the patients with COVID-19

Tong Y, Bao A, Chen H, Huang J, Lv Z, Feng L, Cheng Y, Wang Y, Bai L, Rao W, Zheng H, Wu Z, Qiao B, Zhao Z, Wang H, Li Y.

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Emerging of composition variations of SARS-CoV-2 spike protein and human ACE2 contribute to the level of infection: in silico approaches

AlGhamdi NA, Alsuwat HS, Borgio JF, AbdulAzeez S.

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Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies

Kishk SM, Kishk RM, Yassen ASA, Nafie MS, Nemr NA, ElMasry G, Al-Rejaie S, Simons C.

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Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay

Pitsillou E, Liang J, Karagiannis C, Ververis K, Darmawan KK, Ng K, Hung A, Karagiannis TC.

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The risk of COVID-19 for pregnant women: Evidences of molecular alterations associated with preeclampsia in SARS-CoV-2 infection

Beys-da-Silva WO, da Rosa RL, Santi L, Tureta EF, Terraciano PB, Guimarães JA, Passos EP, Berger M.

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Performance of nucleocapsid and spike-based SARS-CoV-2 serologic assays

Rikhtegaran Tehrani Z, Saadat S, Saleh E, Ouyang X, Constantine N, DeVico AL, Harris AD, Lewis GK, Kottilil S, Sajadi MM.

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Exploring the Potential Mechanism of Shufeng Jiedu Capsule for Treating COVID-19 by Comprehensive Network Pharmacological Approaches and Molecular Docking Validation

Zhuang Z, Zhong X, Zhang H, Chen H, Huang B, Lin D, Wen J.

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Why Severe COVID-19 Patients Are at Greater Risk of Developing Depression: A Molecular Perspective

Bouças AP, Rheinheimer J, Lagopoulos J.

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Immunological strategies against spike protein: Neutralizing antibodies and vaccine development for COVID-19

Huang J, Huang H, Wang D, Wang C, Wang Y.

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In the Age of CoVID: Genomic Changes Over the Lifespan Help Explain Severe SARS-CoV-2 Disease

Beddingfield BJ, Bix GJ.

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Generation of Chicken IgY against SARS-COV-2 Spike Protein and Epitope Mapping

Lu Y, Wang Y, Zhang Z, Huang J, Yao M, Huang G, Ge Y, Zhang P, Huang H, Wang Y, Li H, Wang W.

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Clinical, Radiological, and Molecular Findings of Acute Encephalitis in a COVID-19 Patient: A Rare Case Report

Sattar SBA, Haider MA, Zia Z, Niazi M, Iqbal QZ.

Abstract:

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Genomic Modeling as an Approach to Identify Surrogates for Use in Experimental Validation of SARS-CoV-2 and HuNoV Inactivation by UV-C Treatment

Pendyala B, Patras A, Pokharel B, D'Souza D.

Abstract:

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Overlapping host pathways between SARS-CoV-2 and its potential copathogens: An in silico analysis

Vavougios GD.

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Screening Malaria-box compounds to identify potential inhibitors against SARS-CoV-2 M(pro), using molecular docking and dynamics simulation studies

Ahamad S, Kanipakam H, Birla S, Ali MS, Gupta D.

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Massive dissemination of a SARS-CoV-2 Spike Y839 variant in Portugal

Borges V, Isidro J, Cortes-Martins H, Duarte S, Vieira L, Leite R, Gordo I, Caetano CP, Nunes B, Sá R, Oliveira A, Guiomar R; Portuguese network for SARS-CoV-2 genomics, Gomes JP.

Abstract:

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A natural food preservative peptide nisin can interact with the SARS-CoV-2 spike protein receptor human ACE2

Bhattacharya R, Gupta AM, Mitra S, Mandal S, Biswas SR.

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Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies

M P, Reddy GJ, Hema K, Dodoala S, Koganti B.

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In silico identification of strong binders of the SARS-CoV-2 receptor-binding domain

Behloul N, Baha S, Guo Y, Yang Z, Shi R, Meng J.

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Unbiased Screens Show CD8(+) T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein

Ferretti AP, Kula T, Wang Y, Nguyen DMV, Weinheimer A, Dunlap GS, Xu Q, Nabilsi N, Perullo CR, Cristofaro AW, Whitton HJ, Virbasius A, Olivier KJ Jr, Buckner LR, Alistar AT, Whitman ED, Bertino SA, Chattopadhyay S, MacBeath G.

Abstract:

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Production of Trimeric SARS-CoV-2 Spike Protein by CHO Cells for Serological COVID-19 Testing

Johari YB, Jaffé SRP, Scarrott JM, Johnson AO, Mozzanino T, Pohle TH, Maisuria S, Bhayat-Cammack A, Lambiase G, Brown AJ, Tee KL, Jackson PJ, Wong TS, Dickman MJ, Sargur R, James DC.

Abstract:

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Genomic surveillance of COVID-19 cases in Beijing

Du P, Ding N, Li J, Zhang F, Wang Q, Chen Z, Song C, Han K, Xie W, Liu J, Wang L, Wei L, Ma S, Hua M, Yu F, Wang L, Wang W, An K, Chen J, Liu H, Gao G, Wang S, Huang Y, Wu AR, Wang J, Liu D, Zeng H, Chen C.

Abstract:

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SARS-CoV-2 spike protein: flexibility as a new target for fighting infection

Pierri CL.

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SARS-CoV-2 spike behavior in situ: a Cryo-EM images for a better understanding of the COVID-19 pandemic

Ismail AM, Elfiky AA.

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Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area

Long SW, Olsen RJ, Christensen PA, Bernard DW, Davis JJ, Shukla M, Nguyen M, Saavedra MO, Yerramilli P, Pruitt L, Subedi S, Kuo HC, Hendrickson H, Eskandari G, Nguyen HAT, Long JH, Kumaraswami M, Goike J, Boutz D, Gollihar J, McLellan JS, Chou CW, Javanmardi K, Finkelstein IJ, Musser JM.

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The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

Sitapara RA, Gauthier AG, Patel VS, Lin M, Zur M, Ashby CR Jr, Mantell LL.

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High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity

Lu J, Sun PD.

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Potential of Ficus microcarpa metabolites against SARS-CoV-2 main protease supported by docking studies

Hassan HA, Abdelmohsen UR, Aly OM, Desoukey SY, Mohamed KM, Kamel MS.

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Association of SARS-CoV-2 Genomic Load with COVID-19 Patient Outcomes

Zacharioudakis IM, Prasad PJ, Zervou FN, Basu A, Inglima K, Weisenberg SA, Aguero-Rosenfeld ME.

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Molecular Basis of SARS-CoV-2 Infection and Rational Design of Potential Antiviral Agents: Modeling and Simulation Approaches

Francés-Monerris A, Hognon C, Miclot T, García-Iriepa C, Iriepa I, Terenzi A, Grandemange S, Barone G, Marazzi M, Monari A.

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Profiling SARS-CoV-2 Main Protease (M(PRO)) Binding to Repurposed Drugs Using Molecular Dynamics Simulations in Classical and Neural Network-Trained Force Fields

Gupta A, Zhou HX.

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Uncaria tomentosa (cat's claw): a promising herbal medicine against SARS-CoV-2/ACE-2 junction and SARS-CoV-2 spike protein based on molecular modeling

Yepes-Pérez AF, Herrera-Calderon O, Quintero-Saumeth J.

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The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens

Duan L, Zheng Q, Zhang H, Niu Y, Lou Y, Wang H.

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Pharmacogenomics and Pharmacogenetics: In Silico Prediction of Drug Effects in Treatments for Novel Coronavirus SARS-CoV2 Disease

Cafiero C, Re A, Micera A, Palmirotta R, Monaco D, Romano F, Fabrizio C, Di Francia R, Cacciamani A, Surico PL, D'Amato G, Pisconti S.

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Molecular Detection of Human Coronavirus from North Central Part of Bangladesh Depending on ORF1ab and N Gene

Abedin S, Paul SK, Nasreen SA, Nessa A, Ahmed S, Haque N, Ahamed F, Islam A, Ifa IA, Debnath P, Ahmed MU, Nahar S.

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Antibody Binding to SARS-CoV-2 S Glycoprotein Correlates with but Does Not Predict Neutralization

Ding S, Laumaea A, Benlarbi M, Beaudoin-Bussières G, Gasser R, Medjahed H, Pancera M, Stamatatos L, McGuire AT, Bazin R, Finzi A.

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A Proline-Based Tectons and Supramolecular Synthons for Drug Design 2.0: A Case Study of ACEI

Bojarska J, Remko M, Breza M, Madura I, Fruziński A, Wolf WM.

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In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel coronavirus and cellular proteases and their pharmacokinetic properties

Istifli ES, Netz PA, Sihoglu Tepe A, Husunet MT, Sarikurkcu C, Tepe B.

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Exploring Host Genetic Polymorphisms Involved in SARS-CoV Infection Outcomes: Implications for Personalized Medicine in COVID-19

Ramos-Lopez O, Daimiel L, Ramírez de Molina A, Martínez-Urbistondo D, Vargas JA, Martínez JA.

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Mutations Observed in the SARS-CoV-2 Spike Glycoprotein and Their Effects in the Interaction of Virus with ACE-2 Receptor

Durmaz B, Abdulmajed O, Durmaz R.

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Genomic Cues From Beta-Coronaviruses and Mammalian Hosts Sheds Light on Probable Origins and Infectivity of SARS-CoV-2 Causing COVID-19

Narh CA.

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Computational selection of flavonoid compounds as inhibitors against SARS-CoV-2 main protease, RNA-dependent RNA polymerase and spike proteins: A molecular docking study

Ragavan Rameshkumar M, Indu P, Arunagirinathan N, Venkatadri B, El-Serehy HA, Ahmad A.

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Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria

Tola M, Ajibola O, Idowu ET, Omidiji O, Awolola ST, Amambua-Ngwa A.

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Molecular Docking Studies of Bioactive Nicotiflorin against 6W63 Novel Coronavirus 2019 (COVID-19)

Dubey R, Dubey K.

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Unexpected high frequency of unspecific reactivities by testing pre-epidemic blood specimens from Europe and Africa with SARS-CoV-2 IgG-IgM antibody rapid tests points IgM as Achilles heel

Bouassa RM, Péré H, Tonen-Wolyec S, Longo JD, Moussa S, Mbopi-Keou FX, Mossoro-Kpinde CD, Grésenguet G, Veyer D, Bélec L.

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Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

Jangra S, De Vrieze J, Choi A, Rathnasinghe R, Laghlali G, Uvyn A, Van Herck S, Nuhn L, Deswarte K, Zhong Z, Sanders N, Lienenklaus S, David S, Strohmeier S, Amanat F, Krammer F, Hammad H, Lambrecht BN, Coughlan L, Garcia-Sastre A, De Geest BG, Schotsaert M.

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Single-cell RNA-sequencing reveals dysregulation of molecular programs associated with SARS-CoV-2 severity and outcomes in patients with chronic lung disease

Bui LT, Winters NI, Chung MI, Joseph C, Gutierrez AJ, Habermann AC, Adams TS, Schupp JC, Poli S, Peter LM, Taylor CJ, Blackburn JB, Richmond BW, Nicholson AG, Rassl D, Wallace WA, Rosas IO, Jenkins RG, Kaminski N, Kropski JA, Banovich NE.

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Discovery of small molecule PLpro inhibitor against COVID-19 using structure-based virtual screening, molecular dynamics simulation, and molecular mechanics/Generalized Born surface area (MM/GBSA) calculation

Pang J, Gao S, Sun Z, Yang G.

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Spike mutation D614G alters SARS-CoV-2 fitness

Plante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY.

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The SARS-CoV-2 Spike Glycoprotein as a Drug and Vaccine Target: Structural Insights into Its Complexes with ACE2 and Antibodies

Papageorgiou AC, Mohsin I.

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Repeat COVID-19 Molecular Testing: Correlation of SARS-CoV-2 Culture with Molecular Assays and Cycle Thresholds

Gniazdowski V, Morris CP, Wohl S, Mehoke T, Ramakrishnan S, Thielen P, Powell H, Smith B, Armstrong DT, Herrera M, Reifsnyder C, Sevdali M, Carroll KC, Pekosz A, Mostafa HH.

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High-throughput virtual screening of drug databanks for potential inhibitors of SARS-CoV-2 spike glycoprotein

Awad IE, Abu-Saleh AAA, Sharma S, Yadav A, Poirier RA.

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Supervised molecular dynamics for exploring the druggability of the SARS-CoV-2 spike protein

Deganutti G, Prischi F, Reynolds CA.

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In silico identification of drug candidates against COVID-19

Wu Y, Chang KY, Lou L, Edwards LG, Doma BK, Xie ZR.

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Applying computer simulations in battling with COVID-19, using pre-analyzed molecular and chemical data to face the pandemic

Khazeei Tabari MA, Khoshhal H, Tafazoli A, Khandan M, Bagheri A.

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In silico analysis of ACE2 orthologues to predict animal host range with high susceptibility to SARS-CoV-2

Bouricha EM, Hakmi M, Akachar J, Belyamani L, Ibrahimi A.

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Rapid Genomic Characterization of SARS-CoV-2 by Direct Amplicon-Based Sequencing Through Comparison of MinION and Illumina iSeq100(TM) System

Hourdel V, Kwasiborski A, Balière C, Matheus S, Batéjat CF, Manuguerra JC, Vanhomwegen J, Caro V.

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Identification of alkaloids from Justicia adhatoda as potent SARS CoV-2 main protease inhibitors: An in silico perspective

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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Synthesis, anti-bacterial evaluation, DFT study and molecular docking as a potential 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2 inhibitors of a novel Schiff bases

Al-Janabi ASM, Elzupir AO, Yousef TA.

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A novel rapid detection for SARS-CoV-2 spike 1 antigens using human angiotensin converting enzyme 2 (ACE2)

Lee JH, Choi M, Jung Y, Lee SK, Lee CS, Kim J, Kim J, Kim NH, Kim BT, Kim HG.

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Exploring the intrinsic dynamics of SARS-CoV-2, SARS-CoV and MERS-CoV spike glycoprotein through normal mode analysis using anisotropic network model

Majumder S, Chaudhuri D, Datta J, Giri K.

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Evolutionary dynamics of SARS-CoV-2 nucleocapsid (N) protein and its consequences

Shaminur Rahman M, Rafiul Islam M, Rubayet Ul Alam ASM, Islam I, Nazmul Hoque M, Akter S, Rahaman MM, Sultana M, Anwar Hossain M.

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Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2

Elzupir AO.

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Potential therapeutic use of corticosteroids as SARS CoV-2 main protease inhibitors: a computational study

Ghosh R, Chakraborty A, Biswas A, Chowdhuri S.

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Coding-Complete Genome Sequences of 23 SARS-CoV-2 Samples from the Philippines

Velasco JM, Chinnawirotpisan P, Joonlasak K, Manasatienkij W, Huang A, Valderama MT, Diones PC, Leonardia S, Timbol ML, Navarro FC, Villa V 2nd, Tabinas H Jr, Chua D Jr, Fernandez S, Jones A, Klungthong C.

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Frequency and Duration of SARS-CoV-2 Shedding in Oral Fluid Samples Assessed by a Modified Commercial Rapid Molecular Assay

Bordi L, Sberna G, Lalle E, Piselli P, Colavita F, Nicastri E, Antinori A, Boumis E, Petrosillo N, Marchioni L, Minnucci G, D'Agostini E, Castilletti C, Locatelli F, Zumla A, Ippolito G, Capobianchi MR, On Behalf Of Inmi ReCOVeRI Study Group.

Abstract:

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Detailed Molecular Interactions of Favipiravir with SARS-CoV-2, SARS-CoV, MERS-CoV, and Influenza Virus Polymerases In Silico

Sada M, Saraya T, Ishii H, Okayama K, Hayashi Y, Tsugawa T, Nishina A, Murakami K, Kuroda M, Ryo A, Kimura H.

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Molecular characterization, pathogen-host interaction pathway and in silico approaches for vaccine design against COVID-19

Singh N, Rai S, Singh V, Singh MP.

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, Oliveira de Souza M, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang LA, Abiona OM, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD.

Abstract:

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Alternative clinical specimens for the detection of SARS-CoV-2: A rapid review

Comber L, Walsh KA, Jordan K, O'Brien KK, Clyne B, Teljeur C, Drummond L, Carty PG, De Gascun CF, Smith SM, Harrington P, Ryan M, O'Neill M.

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Mutations in membrane-fusion subunit of spike glycoprotein play crucial role in the recent outbreak of COVID-19

Podder S, Ghosh A, Ghosh T.

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Hordatines as a Potential Inhibitor of COVID-19 Main Protease and RNA Polymerase: An In-Silico Approach

Dahab MA, Hegazy MM, Abbass HS.

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Screening of phytochemicals as potent inhibitor of 3-chymotrypsin and papain-like proteases of SARS-CoV2: an in silico approach to combat COVID-19

Swargiary A, Mahmud S, Saleh MA.

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Prevention of SARS-CoV-2 cell entry: insight from in silico interaction of drug-like alkaloids with spike glycoprotein, human ACE2, and TMPRSS2

Gyebi GA, Adegunloye AP, Ibrahim IM, Ogunyemi OM, Afolabi SO, Ogunro OB.

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Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein

Ropa J, Cooper S, Capitano ML, Van't Hof W, Broxmeyer HE.

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ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Serine Protease 2) Expression and Localization of SARS-CoV-2 Infection in the Human Heart

Sakamoto A, Kawakami R, Kawai K, Gianatti A, Pellegrini D, Kutys R, Guo L, Mori M, Cornelissen A, Sato Y, Bellasi A, Faggi L, Hong C, Romero M, Guagliumi G, Virmani R, Finn AV.

Abstract:

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Specific re-distribution of SARS-CoV-2 variants in the respiratory system and intestinal tract

Du P, Song C, Li R, Song Y, Li J, Ding N, Zhang J, Song R, Han J, Gao G, Yue J, Duan A, Huang Y, An J, Wang J, Zhang F, Chen C, Zeng H.

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Identification of Immunohistochemical Reagents for In Situ Protein Expression Analysis of Coronavirus-associated Changes in Human Tissues

Szabolcs M, Sauter JL, Frosina D, Geronimo JA, Hernandez E, Selbs E, Rapkiewicz AV, Rekhtman N, Baine MK, Jäger E, Travis WD, Jungbluth AA.

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Magnetic beads combined with carbon black-based screen-printed electrodes for COVID-19: A reliable and miniaturized electrochemical immunosensor for SARS-CoV-2 detection in saliva

Fabiani L, Saroglia M, Galatà G, De Santis R, Fillo S, Luca V, Faggioni G, D'Amore N, Regalbuto E, Salvatori P, Terova G, Moscone D, Lista F, Arduini F.

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Nitric oxide (NO) and nanoparticles - potential small tools for the war against COVID-19 and other human coronavirus infections

Pieretti JC, Rubilar O, Weller RB, Tortella GR, Seabra AB.

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Mechanistic insights into dimethyl cardamonin-mediated pharmacological effects: A double control of the AMPK-HMGB1 signaling axis

Bailly C, Vergoten G.

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Thermodynamics of the Interaction between the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus-2 and the Receptor of Human Angiotensin-Converting Enzyme 2. Effects of Possible Ligands

García-Iriepa C, Hognon C, Francés-Monerris A, Iriepa I, Miclot T, Barone G, Monari A, Marazzi M.

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Projected utility of pharmacogenomic testing among individuals hospitalized with COVID-19: A retrospective multicenter study in the United States

Stevenson JM, Alexander GC, Palamuttam N, Mehta HB.

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COVID-19 and the boundaries of open science and innovation: Lessons of traceability from genomic data sharing and biosecurity

Minari J, Yoshizawa G, Shinomiya N.

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Targeting the 3CLpro and RdRp of SARS-CoV-2 with phytochemicals from medicinal plants of the Andean Region: molecular docking and molecular dynamics simulations

Mosquera-Yuqui F, Lopez-Guerra N, Moncayo-Palacio EA.

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Deep mutagenesis in the study of COVID-19: a technical overview for the proteomics community

Procko E.

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Why does the novel Coronavirus Spike Protein interact so strongly with the human ACE2? A thermodynamic answer

de Andrade J, Bruno Gonçalves PF, Netz PA.

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Antibody Response to a Nucleocapsid Epitope as a Marker for COVID-19 Disease Severity

Sen S, Sanders EC, Gabriel KN, Miller BM, Isoda HM, Salcedo GS, Garrido JE, Dyer RP, Nakajima R, Jain A, Santos AM, Bhuvan K, Tifrea DF, Ricks-Oddie JL, Felgner PL, Edwards RA, Majumdar S, Weiss GA.

Abstract:

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Computer-aided drug design against spike glycoprotein of SARS-CoV-2 to aid COVID-19 treatment

Shehroz M, Zaheer T, Hussain T.

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Leaving no stone unturned: Allosteric targeting of SARS-CoV-2 Spike protein at putative druggable sites disrupts human angiotensin-converting enzyme interactions at the receptor binding domain

Olotu FA, Omolabi KF, Soliman MES.

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Mutations of SARS-CoV-2 nsp14 exhibit strong association with increased genome-wide mutation load

Eskier D, Suner A, Oktay Y, Karakülah G.

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COVID-19: molecular and serological detection methods

Dhamad AE, Abdal Rhida MA.

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Experimental and in silico evidence suggests vaccines are unlikely to be affected by D614G mutation in SARS-CoV-2 spike protein

McAuley AJ, Kuiper MJ, Durr PA, Bruce MP, Barr J, Todd S, Au GG, Blasdell K, Tachedjian M, Lowther S, Marsh GA, Edwards S, Poole T, Layton R, Riddell SJ, Drew TW, Druce JD, Smith TRF, Broderick KE, Vasan SS.

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Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

Bos R, Rutten L, van der Lubbe JEM, Bakkers MJG, Hardenberg G, Wegmann F, Zuijdgeest D, de Wilde AH, Koornneef A, Verwilligen A, van Manen D, Kwaks T, Vogels R, Dalebout TJ, Myeni SK, Kikkert M, Snijder EJ, Li Z, Barouch DH, Vellinga J, Langedijk JPM, Zahn RC, Custers J, Schuitemaker H.

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Author Correction: Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

Oude Munnink BB, Nieuwenhuijse DF, Stein M, O'Toole Á, Haverkate M, Mollers M, Kamga SK, Schapendonk C, Pronk M, Lexmond P, van der Linden A, Bestebroer T, Chestakova I, Overmars RJ, van Nieuwkoop S, Molenkamp R, van der Eijk AA, GeurtsvanKessel C, Vennema H, Meijer A, Rambaut A, van Dissel J, Sikkema RS, Timen A, Koopmans M; Dutch-Covid-19 response team.

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Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2

Bracken CJ, Lim SA, Solomon P, Rettko NJ, Nguyen DP, Zha BS, Schaefer K, Byrnes JR, Zhou J, Lui I, Liu J, Pance K; QCRG Structural Biology Consortium, Zhou XX, Leung KK, Wells JA.

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Expression of SARS-CoV-2 entry factors in lung epithelial stem cells and its potential implications for COVID-19

Valyaeva AA, Zharikova AA, Kasianov AS, Vassetzky YS, Sheval EV.

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Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB.

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Neuropilin-1 is a host factor for SARS-CoV-2 infection

Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C, Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM, Cullen PJ, Yamauchi Y.

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Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

Cantuti-Castelvetri L, Ojha R, Pedro LD, Djannatian M, Franz J, Kuivanen S, van der Meer F, Kallio K, Kaya T, Anastasina M, Smura T, Levanov L, Szirovicza L, Tobi A, Kallio-Kokko H, Österlund P, Joensuu M, Meunier FA, Butcher SJ, Winkler MS, Mollenhauer B, Helenius A, Gokce O, Teesalu T, Hepojoki J, Vapalahti O, Stadelmann C, Balistreri G, Simons M.

Abstract:

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Dysregulation of ACE2 Expression and Function in Co-morbid Disease Conditions Possibly Contributes to COVID-19 Complication Severity

Hammoud S, Wehbe Z, Abdelhady S, Kobeissy F, Eid AH, El-Yazbi AF.

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Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

Outlaw VK, Bovier FT, Mears MC, Cajimat MN, Zhu Y, Lin MJ, Addetia A, Lieberman NAP, Peddu V, Xie X, Shi PY, Greninger AL, Gellman SH, Bente DA, Moscona A, Porotto M.

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Transcriptional and proteomic insights into the host response in fatal COVID-19 cases

Wu M, Chen Y, Xia H, Wang C, Tan CY, Cai X, Liu Y, Ji F, Xiong P, Liu R, Guan Y, Duan Y, Kuang D, Xu S, Cai H, Xia Q, Yang D, Wang MW, Chiu IM, Cheng C, Ahern PP, Liu L, Wang G, Surana NK, Xia T, Kasper DL.

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Is the 2019 novel coronavirus related to a spike of cosmic rays?

Wickramasinghe NC.

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Downregulation of Membrane-bound Angiotensin Converting Enzyme 2 (ACE2) Receptor has a Pivotal Role in COVID-19 Immunopathology

Vieira C, Nery L, Martins L, Jabour L, Dias R, Simões E Silva AC.

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Expression Pattern of the SARS-CoV-2 Entry Genes ACE2 and TMPRSS2 in the Respiratory Tract

Liu Y, Qu HQ, Qu J, Tian L, Hakonarson H.

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Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes

Mazzotta S, Carullo G, Schiano Moriello A, Amodeo P, Di Marzo V, Vega-Holm M, Vitale RM, Aiello F, Brizzi A, De Petrocellis L.

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In silico Investigation on the Inhibiting Role of Nicotine/Caffeine by Blocking the S Protein of SARS-CoV-2 Versus ACE2 Receptor

Mohammadi S, Heidarizadeh M, Entesari M, Esmailpour A, Esmailpour M, Moradi R, Sakhaee N, Doustkhah E.

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Functionalized TiO(2) Nanotube-Based Electrochemical Biosensor for Rapid Detection of SARS-CoV-2

Vadlamani BS, Uppal T, Verma SC, Misra M.

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Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report: Erratum

Abstract:

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Students engage in primary literature in molecular biology techniques using an online journal club format

Oxford JT, Jorcyk CL.

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The impact and evaluation of COVID-19 pandemic on the teaching model of medical molecular biology course for undergraduates major in pharmacy

Jiang X, Ning Q.

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SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Banerjee AK, Blanco MR, Bruce EA, Honson DD, Chen LM, Chow A, Bhat P, Ollikainen N, Quinodoz SA, Loney C, Thai J, Miller ZD, Lin AE, Schmidt MM, Stewart DG, Goldfarb D, De Lorenzo G, Rihn SJ, Voorhees RM, Botten JW, Majumdar D, Guttman M.

Abstract:

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Cell-mediated and humoral adaptive immune responses to SARS-CoV-2 are lower in asymptomatic than symptomatic COVID-19 patients

Mazzoni A, Maggi L, Capone M, Spinicci M, Salvati L, Colao MG, Vanni A, Kiros ST, Mencarini J, Zammarchi L, Mantengoli E, Menicacci L, Caldini E, Romagnani S, Liotta F, Morettini A, Rossolini GM, Bartoloni A, Cosmi L, Annunziato F.

Abstract:

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Proteins associated with neutrophil degranulation are upregulated in nasopharyngeal swabs from SARS-CoV-2 patients

Akgun E, Tuzuner MB, Sahin B, Kilercik M, Kulah C, Cakiroglu HN, Serteser M, Unsal I, Baykal AT.

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Using Chou's 5-steps rule to study pharmacophore-based virtual screening of SARS-CoV-2 Mpro inhibitors

Pundir H, Joshi T, Joshi T, Sharma P, Mathpal S, Chandra S, Tamta S.

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Sulodexide may be a real alternative to low molecular weight heparins in the prevention of COVID-19 induced vascular complications

Szolnoky G.

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MCCS: a novel recognition pattern-based method for fast track discovery of anti-SARS-CoV-2 drugs

Feng Z, Chen M, Xue Y, Liang T, Chen H, Zhou Y, Nolin TD, Smith RB, Xie XQ.

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Potential therapeutic effect of turmeric contents against SARS-CoV-2 compared with experimental COVID-19 therapies: in silico study

Emirik M.

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Epigenetic modifications of RNA and their implications in antiviral immunity

Paramasivam A, Priyadharsini JV.

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Antibody Micropatterned Lubricant-Infused Biosensors Enable Sub-Picogram Immunofluorescence Detection of Interleukin 6 in Human Whole Plasma

Shakeri A, Jarad NA, Terryberry J, Khan S, Leung A, Chen S, Didar TF.

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Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID-19 pneumonia

Gibellini L, De Biasi S, Paolini A, Borella R, Boraldi F, Mattioli M, Lo Tartaro D, Fidanza L, Caro-Maldonado A, Meschiari M, Iadisernia V, Bacca E, Riva G, Cicchetti L, Quaglino D, Guaraldi G, Busani S, Girardis M, Mussini C, Cossarizza A.

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Molecular Docking and ADMET Study of Bioactive Compounds of Glycyrrhiza glabra Against Main Protease of SARS-CoV2

Srivastava V, Yadav A, Sarkar P.

Abstract:

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Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor

Onabajo OO, Banday AR, Stanifer ML, Yan W, Obajemu A, Santer DM, Florez-Vargas O, Piontkivska H, Vargas JM, Ring TJ, Kee C, Doldan P, Tyrrell DL, Mendoza JL, Boulant S, Prokunina-Olsson L.

Abstract:

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Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana

Rattanapisit K, Shanmugaraj B, Manopwisedjaroen S, Purwono PB, Siriwattananon K, Khorattanakulchai N, Hanittinan O, Boonyayothin W, Thitithanyanont A, Smith DR, Phoolcharoen W.

Abstract:

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Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2

Basu A, Sarkar A, Maulik U.

Abstract:

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Rational approach toward COVID-19 main protease inhibitors via molecular docking, molecular dynamics simulation and free energy calculation

Keretsu S, Bhujbal SP, Cho SJ.

Abstract:

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SARS-CoV-2 Viral Load, IFNλ Polymorphisms and the Course of COVID-19: An Observational Study

Amodio E, Pipitone RM, Grimaudo S, Immordino P, Maida CM, Prestileo T, Restivo V, Tramuto F, Vitale F, Craxì A, Casuccio A.

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Higher binding affinity of Furin to SARS-CoV-2 spike (S) protein D614G could be associated with higher SARS-CoV-2 infectivity

Mohammad A, Alshawaf E, Marafie SK, Abu-Farha M, Abubaker J, Al-Mulla F.

Abstract:

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Postoperative Onset and Detection of SARS-CoV-2 in Surgically Resected Specimens From Gastrointestinal Cancer Patients With Pre/Asymptomatic COVID-19

Liu YL, Ren J, Yuan JP, Zhang ZJ, Guo WY, Guan Y, Moeckel G, Ahuja N, Fu T.

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Structural and molecular basis of the interaction mechanism of selected drugs towards multiple targets of SARS-CoV-2 by molecular docking and dynamic simulation studies- deciphering the scope of repurposed drugs

Skariyachan S, Gopal D, Chakrabarti S, Kempanna P, Uttarkar A, Muddebihalkar AG, Niranjan V.

Abstract:

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An Overview on the Common Laboratory Parameter Alterations and their Related Molecular Pathways in Screening for COVID-19 Patients

Saberiyan M, Safi A, Kamel A, Movahhed-Abbasabad P, Miralimalek M, Afkhami H, Khaledi M, Teimori H.

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A computational and bioinformatic analysis of ACE2: an elucidation of its dual role in COVID-19 pathology and finding its associated partners as potential therapeutic targets

Khan AT, Khalid Z, Zahid H, Yousaf MA, Shakoori AR.

Abstract:

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Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

Rathnasinghe R, Strohmeier S, Amanat F, Gillespie VL, Krammer F, García-Sastre A, Coughlan L, Schotsaert M, Uccellini M.

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B cell targeting therapies in MS patients during the SARS-CoV-2 pandemic - when immunosuppression meets infection?

Mycko MP.

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SARS-CoV-2 pandemic: a review of molecular diagnostic tools including sample collection and commercial response with associated advantages and limitations

Jayamohan H, Lambert CJ, Sant HJ, Jafek A, Patel D, Feng H, Beeman M, Mahmood T, Nze U, Gale BK.

Abstract:

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Can SARS-CoV-2 Accumulate Mutations in the S-Protein to Increase Pathogenicity?

Padhi AK, Tripathi T.

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Ms for Current Opinion in Systems Biology Special Issue on Systems Immunology The AIRR Community as a model for FAIR stewardship of big immunology data

Scott JK, Breden F.

Abstract:

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Identification of novel mutations in the methyltransferase complex (Nsp10-Nsp16) of SARS-CoV-2

Azad GK.

Abstract:

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Understand variability of COVID-19 through population and tissue variations in expression of SARS-CoV-2 host genes

Chen L, Zheng S.

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Epidemiological and Genomic Analysis of SARS-CoV-2 in 10 Patients From a Mid-Sized City Outside of Hubei, China in the Early Phase of the COVID-19 Outbreak

Chen J, Hilt EE, Li F, Wu H, Jiang Z, Zhang Q, Wang J, Wang Y, Li Z, Tang J, Yang S.

Abstract:

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Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator

Bian J, Li Z.

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Identifying potential anti-COVID-19 pharmacological components of traditional Chinese medicine Lianhuaqingwen capsule based on human exposure and ACE2 biochromatography screening

Chen X, Wu Y, Chen C, Gu Y, Zhu C, Wang S, Chen J, Zhang L, Lv L, Zhang G, Yuan Y, Chai Y, Zhu M, Wu C.

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Kinetics and isotype assessment of antibodies targeting the spike protein receptor-binding domain of severe acute respiratory syndrome-coronavirus-2 in COVID-19 patients as a function of age, biological sex and disease severity

Graham NR, Whitaker AN, Strother CA, Miles AK, Grier D, McElvany BD, Bruce EA, Poynter ME, Pierce KK, Kirkpatrick BD, Stapleton RD, An G, van den Broek-Altenburg E, Botten JW, Crothers JW, Diehl SA.

Abstract:

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Structure-Based Design of Novel Peptidomimetics Targeting the SARS-CoV-2 Spike Protein

Alagumuthu M, Rajpoot S, Baig MS.

Abstract:

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Immunopathogenesis of COVID-19: Summary and Possible Interventions

Jacques FH, Apedaile E.

Abstract:

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Increased Serum Levels of sCD14 and sCD163 Indicate a Preponderant Role for Monocytes in COVID-19 Immunopathology

Gómez-Rial J, Currás-Tuala MJ, Rivero-Calle I, Gómez-Carballa A, Cebey-López M, Rodríguez-Tenreiro C, Dacosta-Urbieta A, Rivero-Velasco C, Rodríguez-Núñez N, Trastoy-Pena R, Rodríguez-García J, Salas A, Martinón-Torres F.

Abstract:

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Strategies for Targeting SARS CoV-2: Small Molecule Inhibitors-The Current Status

Beeraka NM, Sadhu SP, Madhunapantula SV, Rao Pragada R, Svistunov AA, Nikolenko VN, Mikhaleva LM, Aliev G.

Abstract:

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Small Non-coding RNAs: Do They Encode Answers for Controlling SARS-CoV-2 in the Future?

Bhattacharyya P, Biswas SC.

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Translation-Associated Mutational U-Pressure in the First ORF of SARS-CoV-2 and Other Coronaviruses

Khrustalev VV, Giri R, Khrustaleva TA, Kapuganti SK, Stojarov AN, Poboinev VV.

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Proteomics Insights Into the Molecular Basis of SARS-CoV-2 Infection: What We Can Learn From the Human Olfactory Axis

Lachén-Montes M, Corrales FJ, Fernández-Irigoyen J, Santamaría E.

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Anti-IL-6 Versus Anti-IL-6R Blocking Antibodies to Treat Acute Ebola Infection in BALB/c Mice: Potential Implications for Treating Cytokine Release Syndrome

Rubsamen R, Burkholz S, Massey C, Brasel T, Hodge T, Wang L, Herst C, Carback R, Harris P.

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Fenoterol and dobutamine as COVID-19 main protease inhibitors: A virtual screening study

Bolelli K, Ertan-Bolelli T, Unsalan O, Altunayar-Unsalan C.

Abstract:

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Synthesis, spectroscopy, crystal structure, TGA/DTA study, DFT and molecular docking investigations of (E)-4-(4-methylbenzyl)-6-styrylpyridazin-3(2H)-one

Kalai FE, Çınar EB, Lai CH, Daoui S, Chelfi T, Allali M, Dege N, Karrouchi K, Benchat N.

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Anti-COVID-19 terpenoid from marine sources: a docking, ADMET and molecular dynamics study

Sepay N, Sekar A, Halder UC, Alarifi A, Afzal M.

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The BioGRID database: A comprehensive biomedical resource of curated protein, genetic and chemical interactions

Oughtred R, Rust J, Chang C, Breitkreutz BJ, Stark C, Willems A, Boucher L, Leung G, Kolas N, Zhang F, Dolma S, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M.

Abstract:

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Safety, efficacy and patterns of failure after single fraction stereotactic body radiotherapy (SBRT) for oligometastases

Sogono P, Bressel M, David S, Shaw M, Chander S, Chu J, Plumridge N, Byrne K, Hardcastle N, Kron T, Wheeler G, Hanna GG, MacManus M, Ball D, Siva S.

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Assessing the consequences of environmental exposures on the expression of the human receptor and proteases involved in SARS-CoV-2 cell-entry

Watzky M, de Dieuleveult M, Letessier A, Saint-Ruf C, Miotto B.

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Effects of Tanreqing Capsule on the negative conversion time of nucleic acid in patients with COVID-19: A retrospective cohort study

Zhang X, Xue Y, Chen X, Wu JM, Su ZJ, Sun M, Liu LJ, Zhang YB, Zhang YL, Xu GH, Shi MY, Song XM, Lu YF, Chen XR, Zhang W, Chen Q.

Abstract:

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Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

Yuan M, Liu H, Wu NC, Wilson IA.

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MEDT study of the 1,3-DC reaction of diazomethane with Psilostachyin and investigation about the interactions of some pyrazoline derivatives with protease (M(pro)) of nCoV-2

Salah M, Belghiti ME, Aitouna AO, Zeroual A, Jorio S, El Alaoui Abdellaoui H, El Hadki H, Marakchi K, Komiha N.

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NCAM protein and SARS-COV-2 surface proteins: In-silico hypothetical evidence for the immunopathogenesis of Guillain-Barré syndrome

Morsy S.

Abstract:

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RASP: an atlas of transcriptome-wide RNA secondary structure probing data

Li P, Zhou X, Xu K, Zhang QC.

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A Crowned Killer's Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2

Wang S, Trilling M, Sutter K, Dittmer U, Lu M, Zheng X, Yang D, Liu J.

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Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

Carissimo G, Xu W, Kwok I, Abdad MY, Chan YH, Fong SW, Puan KJ, Lee CY, Yeo NK, Amrun SN, Chee RS, How W, Chan S, Fan BE, Andiappan AK, Lee B, Rötzschke O, Young BE, Leo YS, Lye DC, Renia L, Ng LG, Larbi A, Ng LF.

Abstract:

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Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals

Beaudoin-Bussières G, Laumaea A, Anand SP, Prévost J, Gasser R, Goyette G, Medjahed H, Perreault J, Tremblay T, Lewin A, Gokool L, Morrisseau C, Bégin P, Tremblay C, Martel-Laferrière V, Kaufmann DE, Richard J, Bazin R, Finzi A.

Abstract:

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SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans

Nchioua R, Kmiec D, Müller JA, Conzelmann C, Groß R, Swanson CM, Neil SJD, Stenger S, Sauter D, Münch J, Sparrer KMJ, Kirchhoff F.

Abstract:

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Metagenomic sequencing to detect respiratory viruses in persons under investigation for COVID-19

Babiker A, Bradley HL, Stittleburg VD, Ingersoll JM, Key A, Kraft CS, Waggoner JJ, Piantadosi A.

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Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK.

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Morphoproteomics Identifies the Vitamin D Receptor as a Potential Therapeutic Partner in Alveolar Pneumocytes for COVID-19 Infected Patients

Brown RE, Wolf DA, Tahseen D.

Abstract:

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COVID-19 and iron dysregulation: distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein

Ehsani S.

Abstract:

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Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism

Moore SC, Penrice-Randal R, Alruwaili M, Randle N, Armstrong S, Hartley C, Haldenby S, Dong X, Alrezaihi A, Almsaud M, Bentley E, Clark J, García-Dorival I, Gilmore P, Han X, Jones B, Luu L, Sharma P, Shawli G, Sun Y, Zhao Q, Pullan ST, Carter DP, Bewley K, Dunning J, Zhou EM, Solomon T, Beadsworth M, Cruise J, Crook DW, Matthews DA, Davidson AD, Mahmood Z, Aljabr W, Druce J, Vipond R, Ng L, Renia L, Openshaw PJM, Baillie JK, Carroll MW, Stewart J, Darby A, Semple M, Turtle L, Hiscox JA.

Abstract:

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Is There a Link between Bisphenol A (BPA), a Key Endocrine Disruptor, and the Risk for SARS-CoV-2 Infection and Severe COVID-19?

Zahra A, Sisu C, Silva E, De Aguiar Greca SC, Randeva HS, Chatha K, Kyrou I, Karteris E.

Abstract:

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High-Throughput Screening for Inhibitors of the SARS-CoV-2 Protease Using a FRET-Biosensor

Brown AS, Ackerley DF, Calcott MJ.

Abstract:

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Kinetics of Nucleo- and Spike Protein-Specific Immunoglobulin G and of Virus-Neutralizing Antibodies after SARS-CoV-2 Infection

Strömer A, Rose R, Grobe O, Neumann F, Fickenscher H, Lorentz T, Krumbholz A.

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In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors

Ibrahim MAA, Abdelrahman AHM, Hussien TA, Badr EAA, Mohamed TA, El-Seedi HR, Pare PW, Efferth T, Hegazy MF.

Abstract:

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Hyperbolic rules of the cooperative organization of eukaryotic and prokaryotic genomes

Petoukhov SV.

Abstract:

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Comprehensive Analysis of the Glycan Complement of SARS-CoV-2 Spike Proteins Using Signature Ions-Triggered Electron-Transfer/Higher-Energy Collisional Dissociation (EThcD) Mass Spectrometry

Wang D, Baudys J, Bundy JL, Solano M, Keppel T, Barr JR.

Abstract:

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Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy

Shabalin IG, Czub MP, Majorek KA, Brzezinski D, Grabowski M, Cooper DR, Panasiuk M, Chruszcz M, Minor W.

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Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M(pro): insights into enzyme mechanism and drug design

Kneller DW, Phillips G, O'Neill HM, Tan K, Joachimiak A, Coates L, Kovalevsky A.

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Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19

Choudhary S, Sreenivasulu K, Mitra P, Misra S, Sharma P.

Abstract:

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Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis

Marciniec K, Beberok A, Pęcak P, Boryczka S, Wrześniok D.

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Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening

Zhu W, Xu M, Chen CZ, Guo H, Shen M, Hu X, Shinn P, Klumpp-Thomas C, Michael SG, Zheng W.

Abstract:

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Why Companion Animals Are Beneficial During COVID-19 Pandemic

Hunjan UG, Reddy J.

Abstract:

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How pets factor into healthcare decisions for COVID-19: A One Health perspective

Applebaum JW, Adams BL, Eliasson MN, Zsembik BA, McDonald SE.

Abstract:

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Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening

Senok A, Alsuwaidi H, Atrah Y, Al Ayedi O, Al Zahid J, Han A, Al Marzooqi A, Al Heialy S, Altrabulsi B, AbdelWareth L, Idaghdour Y, Ali R, Loney T, Alsheikh-Ali A.

Abstract:

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Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19

Li C, Zhao H, Wang B.

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Rapid genomic characterization of SARS-CoV-2 viruses from clinical specimens using nanopore sequencing

Li J, Wang H, Mao L, Yu H, Yu X, Sun Z, Qian X, Cheng S, Chen S, Chen J, Pan J, Shi J, Wang X.

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Found: genes that sway the course of the coronavirus

Kaiser J.

Abstract:

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Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography

Kneller DW, Phillips G, Weiss KL, Pant S, Zhang Q, O'Neill HM, Coates L, Kovalevsky A.

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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero

Abstract:

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mTORC1 Hyperactivation in LAM Leads to ACE2 Upregulation in Type II Pneumocytes: Implications for COVID-19

Tang Y, Kwiatkowski DJ, Henske EP.

Abstract:

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Comparative evaluation of nasopharyngeal swab and saliva specimens for the molecular detection of SARS-CoV-2 RNA in Japanese patients with COVID-19

Sakanashi D, Asai N, Nakamura A, Miyazaki N, Kawamoto Y, Ohno T, Yamada A, Koita I, Suematsu H, Hagihara M, Shiota A, Kurumiya A, Sakata M, Kato S, Muramatsu Y, Koizumi Y, Kishino T, Ohashi W, Yamagishi Y, Mikamo H.

Abstract:

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Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patients

Al-Khawaga S, Abdelalim EM.

Abstract:

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Papain-like cysteine proteinase zone (PCP-zone) and PCP structural catalytic core (PCP-SCC) of enzymes with cysteine proteinase fold

Denessiouk K, Uversky VN, Permyakov SE, Permyakov EA, Johnson MS, Denesyuk AI.

Abstract:

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Genomic evidence for reinfection with SARS-CoV-2: a case study

Tillett RL, Sevinsky JR, Hartley PD, Kerwin H, Crawford N, Gorzalski A, Laverdure C, Verma SC, Rossetto CC, Jackson D, Farrell MJ, Van Hooser S, Pandori M.

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The Architecture of Inactivated SARS-CoV-2 with Postfusion Spikes Revealed by Cryo-EM and Cryo-ET

Liu C, Mendonça L, Yang Y, Gao Y, Shen C, Liu J, Ni T, Ju B, Liu C, Tang X, Wei J, Ma X, Zhu Y, Liu W, Xu S, Liu Y, Yuan J, Wu J, Liu Z, Zhang Z, Liu L, Wang P, Zhang P.

Abstract:

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A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model

Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüs

Abstract:

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Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2-Specific IgG

Schwarzkopf S, Krawczyk A, Knop D, Klump H, Heinold A, Heinemann FM, Thümmler L, Temme C, Breyer M, Witzke O, Dittmer U, Lenz V, Horn PA, Lindemann M.

Abstract:

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Real-Time Spatiotemporal Analysis of Microepidemics of Influenza and COVID-19 Based on Hospital Network Data: Colocalization of Neighborhood-Level Hotspots

Mylona EK, Shehadeh F, Kalligeros M, Benitez G, Chan PA, Mylonakis E.

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The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Khalil A, Tazeddinova D.

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IDseq-An open source cloud-based pipeline and analysis service for metagenomic pathogen detection and monitoring

Kalantar KL, Carvalho T, de Bourcy CFA, Dimitrov B, Dingle G, Egger R, Han J, Holmes OB, Juan YF, King R, Kislyuk A, Lin MF, Mariano M, Morse T, Reynoso LV, Cruz DR, Sheu J, Tang J, Wang J, Zhang MA, Zhong E, Ahyong V, Lay S, Chea S, Bohl JA, Manning JE, Tato CM, DeRisi JL.

Abstract:

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The inhaled steroid ciclesonide blocks SARS-CoV-2 RNA replication by targeting the viral replication-transcription complex in cultured cells

Matsuyama S, Kawase M, Nao N, Shirato K, Ujike M, Kamitani W, Shimojima M, Fukushi S.

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Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell-cell fusion

Thakur N, Conceicao C, Isaacs A, Human S, Modhiran N, McLean RK, Pedrera M, Tan TK, Rijal P, Townsend A, Taylor G, Young PR, Watterson D, Chappell KJ, Graham SP, Bailey D.

Abstract:

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Saliva specimens for detection of severe acute respiratory syndrome coronavirus 2 in Kuwait: A cross-sectional study

Altawalah H, AlHuraish F, Alkandari WA, Ezzikouri S.

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The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier

Buzhdygan TP, DeOre BJ, Baldwin-Leclair A, Bullock TA, McGary HM, Khan JA, Razmpour R, Hale JF, Galie PA, Potula R, Andrews AM, Ramirez SH.

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Highly Effective Inactivation of SARS-CoV-2 by Conjugated Polymers and Oligomers

Schanze KS, Whitten DG, Kell AM, Chi EY, Ista LK, Monge FA, Jagadesan P, Bondu V, Donabedian PL.

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Variability of Salivary and Nasal Specimens for SARS-CoV-2 Detection

Manabe YC, Reuland C, Yu T, Azamfirei R, Church T, Brown DM, Sewell TT, Hardick JP, Blair PW, Heaney CD, Pekosz A, Thomas DL.

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SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

Elizondo V, Harkins GW, Mabvakure B, Smidt S, Zappile P, Marier C, Maurano MT, Perez V, Mazza N, Beloso C, Ifran S, Fernandez M, Santini A, Perez V, Estevez V, Nin M, Manrique G, Perez L, Ross F, Boschi S, Zubillaga MN, Balleste R, Dellicour S, Heguy A, Duerr R.

Abstract:

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Activation of ACE2 and interferon-stimulated transcriptomes in human airway epithelium is curbed by Janus Kinase inhibitors

Lee HK, Jung O, Hennighausen L.

Abstract:

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D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction

Gobeil S, Janowska K, McDowell S, Mansouri K, Parks R, Manne K, Stalls V, Kopp M, Henderson R, Edwards RJ, Haynes BF, Acharya P.

Abstract:

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Angiotensin-converting enzyme 2 (ACE2) is upregulated in Alzheimer's disease brain

Ding Q, Shults NV, Harris BT, Suzuki YJ.

Abstract:

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Umbilical cord blood derived microglia-like cells to model COVID-19 exposure

Sheridan SD, Thanos JM, De Guzman RM, McCrea LT, Horng J, Fu T, Sellgren CM, Perlis RH, Edlow AG.

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CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entire SARS-CoV-2 proteome and show kinetics of early differentiation

Kared H, Redd AD, Bloch EM, Bonny TS, Sumatoh H, Kairi F, Carbajo D, Abel B, Newell EW, Bettinotti MP, Benner SE, Patel EU, Littlefield K, Laeyendecker O, Shoham S, Sullivan D, Casadevall A, Pekosz A, Nardin A, Fehlings M, Tobian AA, Quinn TC.

Abstract:

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Batch-Corrected Distance Mitigates Temporal and Spatial Variability for Clustering and Visualization of Single-Cell Gene Expression Data

Liang S, Dou J, Iqbal R, Chen K.

Abstract:

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Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2

Azouz NP, Klingler AM, Callahan V, Akhrymuk IV, Elez K, Raich L, Henry BM, Benoit JL, Benoit SW, Noé F, Kehn-Hall K, Rothenberg ME.

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Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3- O -sulfated heparan sulfate

Tiwari V, Tandon R, Sankaranarayanan NV, Beer JC, Kohlmeir EK, Swanson-Mungerson M, Desai UR.

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Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection

Flynn RA, Belk JA, Qi Y, Yasumoto Y, Schmitz CO, Mumbach MR, Limaye A, Wei J, Alfajaro MM, Parker KR, Chang HY, Horvath TL, Carette JE, Bertozzi C, Wilen CB, Satpathy AT.

Abstract:

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SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells

Suzuki YJ, Nikolaienko SI, Dibrova VA, Dibrova YV, Vasylyk VM, Novikov MY, Shults NV, Gychka SG.

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Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

Schneider WM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, Le Pen J, Michailidis E, Ricardo-Lax I, Peace A, Stenzel AF, Lowe SW, MacDonald MR, Rice CM, Poirier JT.

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Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters

Yuan S, Yin X, Meng X, Chan J, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan C, Poon V, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Sze KH, Zhang J, Chu H, Kok KH, To K, Jin DY, Sun R, Chanda S, Yuen KY.

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Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

Rosenke K, Hansen F, Schwarz B, Feldmann F, Haddock E, Rosenke R, Meade-White K, Okumura A, Leventhal S, Hawman D, Ricotta E, Bosio C, Saturday G, Feldmann H, Jarvis M.

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Syncytia formation by SARS-CoV-2 infected cells

Buchrieser J, Dufloo J, Hubert M, Monel B, Planas D, Michael Rajah M, Planchais C, Porrot F, Guivel-Benhassine F, Van der Werf S, Casartelli N, Mouquet H, Bruel T, Schwartz O.

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IL-18-dependent MAIT cell activation in COVID-19

Gea-Mallorquí E.

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From People to Panthera: Natural SARS-CoV-2 Infection in Tigers and Lions at the Bronx Zoo

McAloose D, Laverack M, Wang L, Killian ML, Caserta LC, Yuan F, Mitchell PK, Queen K, Mauldin MR, Cronk BD, Bartlett SL, Sykes JM, Zec S, Stokol T, Ingerman K, Delaney MA, Fredrickson R, Ivančić M, Jenkins-Moore M, Mozingo K, Franzen K, Bergeson NH, Goodman L, Wang H, Fang Y, Olmstead C, McCann C, Thomas P, Goodrich E, Elvinger F, Smith DC, Tong S, Slavinski S, Calle PP, Terio K, Torchetti MK, Diel DG.

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Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

Li Z, Li X, Huang YY, Wu Y, Liu R, Zhou L, Lin Y, Wu D, Zhang L, Liu H, Xu X, Yu K, Zhang Y, Cui J, Zhan CG, Wang X, Luo HB.

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Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

Heer CD, Sanderson DJ, Voth LS, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C.

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Genomic Diversity and Hotspot Mutations in 30,983 SARS-CoV-2 Genomes: Moving Toward a Universal Vaccine for the "Confined Virus"?

Alouane T, Laamarti M, Essabbar A, Hakmi M, Bouricha EM, Chemao-Elfihri MW, Kartti S, Boumajdi N, Bendani H, Laamarti R, Ghrifi F, Allam L, Aanniz T, Ouadghiri M, El Hafidi N, El Jaoudi R, Benrahma H, Attar JE, Mentag R, Sbabou L, Nejjari C, Amzazi S, Belyamani L, Ibrahimi A.

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Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy

Yellapu NK, Patel S, Zhang B, Meier R, Neums L, Pei D, Xia Q, Rotich D, Zimmermann RC, Nissen E, Bell-Glenn S, Shae W, Hu J, Chalise P, Chollet-Hinton L, Koestler DC, Thompson JA.

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GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies

Wu CY, Lin YS, Yang YH, Shu LH, Cheng YC, Liu HT.

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Non-synonymous Mutations of SARS-CoV-2 Leads Epitope Loss and Segregates its Variants

Gupta AM, Chakrabarti J, Mandal S.

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Mesenchymal stem cell immunomodulation and regeneration therapeutics as an ameliorative approach for COVID-19 pandemics

Yadav P, Vats R, Bano A, Bhardwaj R.

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Analysis of SARS-CoV-2 mutations in Mexico, Belize and isolated regions of Guatemala and its implication in the diagnosis

Hernández-Huerta MT, Mayoral LP, Díaz CR, Cruz MM, Mayoral-Andrade G, Navarro LMS, Pina Canseco MDS, Parada EC, Cruz RM, Mayoral EP, Santiago ADP, Martínez GV, Pérez-Campos E, Matias-Cervantes CA.

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Co-Expression of Mitochondrial Genes and ACE2 in Cornea Involved in COVID-19

Yuan J, Fan D, Xue Z, Qu J, Su J.

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Generation of Recombinant SARS-CoV-2 Using a Bacterial Artificial Chromosome

Chiem K, Ye C, Martinez-Sobrido L.

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Could bacteriophages be the answer to the COVID-19 crisis?

Martinecz A, Wojewodzic MW.

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Association between HLA gene polymorphisms and mortality of COVID-19: An in silico analysis

Tomita Y, Ikeda T, Sato R, Sakagami T.

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Repositioning microbial biotechnology against COVID-19: the case of microbial production of flavonoids

Goris T, Pérez-Valero Á, Martínez I, Yi D, Fernández-Calleja L, San León D, Bornscheuer UT, Magadán-Corpas P, Lombó F, Nogales J.

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Cysteine focused covalent inhibitors against the main protease of SARS-CoV-2

Paul AS, Islam R, Parves MR, Mamun AA, Shahriar I, Hossain MI, Hossain MN, Ali MA, Halim MA.

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Puzzling out the COVID-19: Therapy targeting HLA-G and HLA-E

Zidi I.

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A coronavirus online analysis platform at the National Genomics Data Center

Gong Z, Zhu J, Li C, Jiang S, Ma L, Tang B, Zou D, Chen M, Sun Y, Song S, Zhang Z, Xiao J, Xue Y, Bao Y, Du Z, Zhao WM.

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GESS: a database of global evaluation of SARS-CoV-2/hCoV-19 sequences

Fang S, Li K, Shen J, Liu S, Liu J, Yang L, Hu CD, Wan J.

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SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr, Bjorkman PJ.

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COVID-Align: Accurate online alignment of hCoV-19 genomes using a profile HMM

Lemoine F, Blassel L, Voznica J, Gascuel O.

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Serum ACE-2, angiotensin II, and aldosterone levels are unchanged in patients with COVID-19

Rieder M, Wirth L, Pollmeier L, Jeserich M, Goller I, Baldus N, Schmid B, Busch HJ, Hofmann M, Kern W, Bode C, Duerschmied D, Lother A.

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High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2

Smith E, Davis-Gardner ME, Garcia-Ordonez RD, Nguyen TT, Hull M, Chen E, Baillargeon P, Scampavia L, Strutzenberg T, Griffin P, Farzan M, Spicer TP.

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Risk Variant for Severe COVID-19 Inherited from Neanderthals

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Syntheaâ„¢ Novel coronavirus (COVID-19) model and synthetic data set

Walonoski J, Klaus S, Granger E, Hall D, Gregorowicz A, Neyarapally G, Watson A, Eastman J.

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Assessing the SARS-CoV-2 threat to wildlife: Potential risk to a broad range of mammals

Martínez-Hernández F, Isaak-Delgado AB, Alfonso-Toledo JA, Muñoz-García CI, Villalobos G, Aréchiga-Ceballos N, Rendón-Franco E.

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EXPLORING SURFACE GLYCOPROTEIN TO DESIGN MULTI-EPITOPE VACCINE AGAINST COVID-19

Oladipo EK, Ajayi AF, Ariyo OE, Onile SO, Jimah EM, Ezediuno OL, Adebayo OI, Adebayo ET, Odeyemi AN, Oyeleke MO, Oyewole MP, Oguntomi AS, Akindiya OE, Olamoyegun BO, Aremu VO, Arowosaye AO, Aboderin DO, Bello BH, Senbadejo YT, Awoyelu EH, Oladipo AA, Oladipo BB, Ajayi LO, Majolagbe ON, Oyawoye OM, Oloke JK.

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Insights on SARS-CoV-2 Molecular Interactions With the Renin-Angiotensin System

Costa LB, Perez LG, Palmeira VA, Macedo E Cordeiro T, Ribeiro VT, Lanza K, Simões E Silva AC.

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Applying fixed point methods and fractional operators in the modelling of novel coronavirus 2019-nCoV/SARS-CoV-2

Panda SK.

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Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis

Motta Junior JDS, Miggiolaro AFRDS, Nagashima S, de Paula CBV, Baena CP, Scharfstein J, de Noronha L.

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Blocking of the High-Affinity Interaction-Synapse Between SARS-CoV-2 Spike and Human ACE2 Proteins Likely Requires Multiple High-Affinity Antibodies: An Immune Perspective

Khatri I, Staal FJT, van Dongen JJM.

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Commentary: APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort

Kasparian K, Graykowski D, Cudaback E.

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The Potential of Antiviral Peptides as COVID-19 Therapeutics

Mahendran ASK, Lim YS, Fang CM, Loh HS, Le CF.

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In Silico Prediction of Molecular Targets of Astragaloside IV for Alleviation of COVID-19 Hyperinflammation by Systems Network Pharmacology and Bioinformatic Gene Expression Analysis

Ge C, He Y.

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[Glycosylation, Ligand Binding Sites and Antigenic Variations Between Membrane Glycoprotein of COVID-19 and Related Coronaviruses]

Dawood AA.

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Promising terpenes as SARS-CoV-2 spike receptor-binding domain (RBD) attachment inhibitors to the human ACE2 receptor: Integrated computational approach

Muhseen ZT, Hameed AR, Al-Hasani HMH, Tahir Ul Qamar M, Li G.

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Neuroprotective Immunity by Essential Nutrient "Choline" for the Prevention of SARS CoV2 Infections: An In Silico Study by Molecular Dynamics Approach

Chowdhury P, Pathak P.

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Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions

Gavor E, Choong YK, Er SY, Sivaraman H, Sivaraman J.

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Glycyrrhizic acid exerts inhibitory activity against the spike protein of SARS-CoV-2

Yu S, Zhu Y, Xu J, Yao G, Zhang P, Wang M, Zhao Y, Lin G, Chen H, Chen L, Zhang J.

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Antibody dynamics to SARS-CoV-2 in asymptomatic COVID-19 infections

Lei Q, Li Y, Hou HY, Wang F, Ouyang ZQ, Zhang Y, Lai DY, Jo-Lewis BN, Xu ZW, Zhang B, Chen H, Xue JB, Lin XS, Zheng YX, Yao ZJ, Wang XN, Yu CZ, Jiang HW, Zhang HN, Qi H, Guo SJ, Huang SH, Sun ZY, Tao SC, Fan XL.

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Immunoinformatics approach to understand molecular interaction between multi-epitopic regions of SARS-CoV-2 spike-protein with TLR4/MD-2 complex

Bhattacharya M, Sharma AR, Mallick B, Sharma G, Lee SS, Chakraborty C.

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High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2

Zinzula L, Basquin J, Bohn S, Beck F, Klumpe S, Pfeifer G, Nagy I, Bracher A, Hartl FU, Baumeister W.

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Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study

Brendish NJ, Poole S, Naidu VV, Mansbridge CT, Norton NJ, Wheeler H, Presland L, Kidd S, Cortes NJ, Borca F, Phan H, Babbage G, Visseaux B, Ewings S, Clark TW.

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The role for the metagenome in the pathogenesis of COVID-19

Friedland RP, Haribabu B.

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Molecular mechanisms of the novel coronavirus SARS-CoV-2 and potential anti-COVID19 pharmacological targets since the outbreak of the pandemic

Vlachakis D, Papakonstantinou E, Mitsis T, Pierouli K, Diakou I, Chrousos G, Bacopoulou F.

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Machine learning techniques for sequence-based prediction of viral-host interactions between SARS-CoV-2 and human proteins

Dey L, Chakraborty S, Mukhopadhyay A.

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Molecular modeling study of tectoquinone and acteoside from Tectona grandis linn: a new SARS-CoV-2 main protease inhibitor against COVID-19

Kallingal A, Thachan Kundil V, Ayyolath A, Karlapudi AP, Muringayil Joseph T, E JV.

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Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2

Rogstam A, Nyblom M, Christensen S, Sele C, Talibov VO, Lindvall T, Rasmussen AA, André I, Fisher Z, Knecht W, Kozielski F.

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Host Receptors of Influenza Viruses and Coronaviruses-Molecular Mechanisms of Recognition

Sriwilaijaroen N, Suzuki Y.

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Managing Lung Nodules Using Telemedicine and Molecular Biomarkers During the COVID-19 Pandemic

Springmeyer SC, Jett J, Bhadra K, Kheir F, Majid A.

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First COVID-19 Case in Zambia - Comparative phylogenomic analyses of SARS-CoV-2 detected in African countries

Simulundu E, Mupeta F, Chanda-Kapata P, Saasa N, Changula K, Muleya W, Chitanga S, Mwanza M, Simusika P, Chambaro H, Mubemba B, Kajihara M, Chanda D, Mulenga L, Fwoloshi S, Shibemba AL, Kapaya F, Zulu P, Musonda K, Monze M, Sinyange N, Liwewe MM, Kapin'a M, Chipimo PJ, Hamoonga R, Simwaba D, Ngosa W, Morales AN, Kayeyi N, Tembo J, Bates M, Orba Y, Sawa H, Takada A, Nalubamba KS, Malama K, Mukonka V, Zumla A, Kapata N.

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Emergence and molecular mechanisms of SARS-CoV-2 and HIV to target host cells and potential therapeutics

Saleemi MA, Ahmad B, Benchoula K, Vohra MS, Mea HJ, Chong PP, Palanisamy NK, Wong EH.

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Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?

Morris G, Athan E, Walder K, Bortolasci CC, O'Neil A, Marx W, Berk M, Carvalho AF, Maes M, Puri BK.

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Use of protease inhibitors for the prevention of COVID-19

Sagawa T, Inoue KI, Takano H.

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Air and surface contamination in non-health care settings among 641 environmental specimens of 39 COVID-19 cases

Luo L, Liu D, Zhang H, Li Z, Zhen R, Zhang X, Xie H, Song W, Liu J, Huang Q, Liu J, Yang X, Chen Z, Mao C.

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Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers and convalescent plasma donors

Zeng C, Evans JP, Pearson R, Qu P, Zheng YM, Robinson RT, Hall-Stoodley L, Yount JS, Pannu S, Mallampalli RK, Saif L, Oltz E, Lozanski G, Liu SL.

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Whole genome sequencing and phylogenetic classification of Tunisian SARS-CoV-2 strains from patients of the Military Hospital in Tunis

Handrick S, Bestehorn-Willmann M, Eckstein S, Walter MC, Antwerpen MH, Naija H, Stoecker K, Wölfel R, Ben Moussa M.

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Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Protein in the Ocular Tissues of a Patient Previously Infected With Coronavirus Disease 2019

Yan Y, Diao B, Liu Y, Zhang W, Wang G, Chen X.

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Teaching biochemistry and molecular biology online in Nigeria: Missed opportunities during the COVID-19 pandemic

Umar Aliyu R, Hassan Yankuzo M, Hassan Wara S.

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Computer-aided prediction and design of IL-6 inducing peptides: IL-6 plays a crucial role in COVID-19

Dhall A, Patiyal S, Sharma N, Usmani SS, Raghava GPS.

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Predicting susceptibility for SARS-CoV-2 infection in domestic and wildlife animals using ACE2 protein sequence homology

Kumar A, Pandey SN, Pareek V, Narayan RK, Faiq MA, Kumari C.

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Prepare for the Future: Dissecting the Spike to Seek Broadly Neutralizing Antibodies and Universal Vaccine for Pandemic Coronaviruses

Vangelista L, Secchi M.

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Preemptive interleukin-6 blockade in patients with COVID-19

Guillén L, Padilla S, Fernández M, Agulló V, García JA, Telenti G, García-Abellán J, Botella Á, Gutiérrez F, Masiá M.

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Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients

Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC.

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Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients

Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, Atyeo C, Iafrate AJ, Calderwood SB, Lauer SA, Yu J, Li Z, Feldman J, Hauser BM, Caradonna TM, Branda JA, Turbett SE, LaRocque RC, Mellon G, Barouch DH, Schmidt AG, Azman AS, Alter G, Ryan ET, Harris JB, Charles RC.

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Metagenome of a Bronchoalveolar Lavage Fluid Sample from a Confirmed COVID-19 Case in Quito, Ecuador, Obtained Using Oxford Nanopore MinION Technology

Márquez S, Prado-Vivar B, Guadalupe JJ, Gutierrez B, Becerra-Wong M, Jibaja M, Tobar M, Barragán V, Rojas-Silva P, Coloma J, Trueba G, Grunauer M, Cárdenas P.

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Comparison of SARS-CoV-2 RT-PCR on a high-throughput molecular diagnostic platform and the cobas SARS-CoV-2 test for the diagnostic of COVID-19 on various clinical samples

Opota O, Brouillet R, Greub G, Jaton K.

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Molecular dynamics analysis predicts ritonavir and naloxegol strongly block the SARS-CoV-2 spike protein-hACE2 binding

Bagheri M, Niavarani A.

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Finding potent inhibitors for COVID-19 main protease (M(pro)): an in silico approach using SARS-CoV-3CL protease inhibitors for combating CORONA

Motiwale M, Yadav NS, Kumar S, Kushwaha T, Choudhir G, Sharma S, Singour PK.

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Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications

Iwasaki M, Saito J, Zhao H, Sakamoto A, Hirota K, Ma D.

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Molecular docking between human TMPRSS2 and SARS-CoV-2 spike protein: conformation and intermolecular interactions

Hussain M, Jabeen N, Amanullah A, Baig AA, Aziz B, Shabbir S, Raza F, Uddin N.

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How the COVID-19 Pandemic Impacted Oncological Molecular Diagnosis: A Picture from a National Reference Center for Molecular Pathology

Daniel Pinto, Cirnes L, Regina Pinto, Pina MJ, Troncone G, Schmitt F.

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Investigating Potential Inhibitory Effect of Uncaria tomentosa (Cat's Claw) against the Main Protease 3CL(pro) of SARS-CoV-2 by Molecular Modeling

Yepes-Pérez AF, Herrera-Calderon O, Sánchez-Aparicio JE, Tiessler-Sala L, Maréchal JD, Cardona-G W.

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COVID-19: molecular targets, drug repurposing and new avenues for drug discovery

Senger MR, Evangelista TCS, Dantas RF, Santana MVDS, Gonçalves LCS, de Souza Neto LR, Ferreira SB, Silva-Junior FP.

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Flavonoid glycosides and their putative human metabolites as potential inhibitors of the SARS-CoV-2 main protease (Mpro) and RNA-dependent RNA polymerase (RdRp)

da Silva FMA, da Silva KPA, de Oliveira LPM, Costa EV, Koolen HH, Pinheiro MLB, de Souza AQL, de Souza ADL.

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IFCC interim guidelines on molecular testing of SARS-CoV-2 infection

Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Gramegna M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Singh K, Ferrari M, Najjar O, Horvath A, Adeli K, Lippi G.

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Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic

Zhang W, Govindavari JP, Davis BD, Chen SS, Kim JT, Song J, Lopategui J, Plummer JT, Vail E.

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Discovery of potent inhibitors for SARS-CoV-2's main protease by ligand-based/structure-based virtual screening, MD simulations, and binding energy calculations

Abu-Saleh AAA, Awad IE, Yadav A, Poirier RA.

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Integrated network pharmacology and molecular docking strategy to explore the mechanism of medicinal and edible Astragali Radix-Atractylodis Macrocephalae Rhizoma acting on pneumonia via immunomodulation

Wu Q, Hu Y.

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Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area

Long SW, Olsen RJ, Christensen PA, Bernard DW, Davis JJ, Shukla M, Nguyen M, Saavedra MO, Yerramilli P, Pruitt L, Subedi S, Kuo HC, Hendrickson H, Eskandari G, Nguyen HAT, Long JH, Kumaraswami M, Goike J, Boutz D, Gollihar J, McLellan JS, Chou CW, Javanmardi K, Finkelstein IJ, Musser J.

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Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2

Venkatakrishnan AJ, Kayal N, Anand P, Badley AD, Church GM, Soundararajan V.

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Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines

Rao L, Xia S, Xu W, Tian R, Yu G, Gu C, Pan P, Meng QF, Cai X, Qu D, Lu L, Xie Y, Jiang S, Chen X.

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In silico exploration of small-molecule α-helix mimetics as inhibitors of SARS-COV-2 attachment to ACE2

Hakmi M, Bouricha ELM, Akachar J, Lmimouni B, El Harti J, Belyamani L, Ibrahimi A.

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Covid-19 and kidney injury: Pathophysiology and molecular mechanisms

Ahmadian E, Hosseiniyan Khatibi SM, Razi Soofiyani S, Abediazar S, Shoja MM, Ardalan M, Zununi Vahed S.

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1,2,4 triazolo[1,5-a] pyrimidin-7-ones as novel SARS-CoV-2 Main protease inhibitors: In silico screening and molecular dynamics simulation of potential COVID-19 drug candidates

Kavitha K, Sivakumar S, Ramesh B.

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Human anatomy education and management of anatomic specimens during and after COVID-19 pandemic: Ethical, legal and biosafety aspects

Lemos GA, Araújo DN, de Lima FJC, Bispo RFM.

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Microbe hunting in the modern era: reflecting on a decade of microbial genomic epidemiology

Baker KS.

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Novel hybrid antiviral VTRRT-13V2.1 against SARS-CoV2 main protease: retro-combinatorial synthesis and molecular dynamics analysis

Tiwari V.

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Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2

Wu L, Chen Q, Liu K, Wang J, Han P, Zhang Y, Hu Y, Meng Y, Pan X, Qiao C, Tian S, Du P, Song H, Shi W, Qi J, Wang HW, Yan J, Gao GF, Wang Q.

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Structural Insight into the Recognition of S-Adenosyl-L-Homocysteine and Sinefungin in SARS-CoV-2 Nsp16/Nsp10 RNA Cap 2'-O-Methyltransferase

Mahalapbutr P, Kongtaworn N, Rungrotmongkol T.

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SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals

Lam SD, Bordin N, Waman VP, Scholes HM, Ashford P, Sen N, van Dorp L, Rauer C, Dawson NL, Pang CSM, Abbasian M, Sillitoe I, Edwards SJL, Fraternali F, Lees JG, Santini JM, Orengo CA.

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COVID-19 and upper respiratory tract: Collecting swab specimens from patients inhaling corticosteroids

Siniorakis E, Arvanitakis S, Sfakianaki T, Katsianis A, Sinaniotis A, Papagiannopoulou V.

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Confidence intervals for the COVID-19 neutralizing antibody retention rate in the Korean population

Apio C, Kamruzzaman M, Park T.

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VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data

Yasumizu Y, Hara A, Sakaguchi S, Ohkura N.

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Ethical Convergence and Ethical Possibilities: The Implications of New Materialism for Understanding the Molecular Turn in HIV, the Response to COVID-19, and the Future of Bioethics

Guta A, Gagnon M, Philbin MM.

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Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus

Jiang Y, Liu L, Manning M, Bonahoom M, Lotvola A, Yang Z, Yang ZQ.

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Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species

Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS.

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Identification, protein antiglycation, antioxidant, antiproliferative, and molecular docking of novel bioactive peptides produced from hydrolysis of Lens culinaris

Kuerban A, Al-Malki AL, Kumosani TA, Sheikh RA, Al-Abbasi FAM, Alshubaily FA, Omar Abulnaja K, Salama Moselhy S.

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A Comparison of Five SARS-CoV-2 Molecular Assays With Clinical Correlations

Procop GW, Brock JE, Reineks EZ, Shrestha NK, Demkowicz R, Cook E, Ababneh E, Harrington SM.

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Genetic variants mimicking therapeutic inhibition of IL-6 receptor signaling and risk of COVID-19

Bovijn J, Lindgren CM, Holmes MV.

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Computational Evaluation of the Inhibition Efficacies of HIV Antivirals on SARS-CoV-2 (COVID-19) Protease and Identification of 3D Pharmacophore and Hit Compounds

Raphael VP, Shanmughan SK.

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PPARγ cistrome repression during activation of lung monocyte-macrophages in severe COVID-19

Desterke C, Turhan AG, Bennaceur-Griscelli A, Griscelli F.

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Credible Protein Targets and Curative Strategies for COVID-19: a Review

Singh P, Mishra N, Singh N, Nisha R, Pal RR, Singh S, Maurya P, Saraf SA.

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Identification of twenty-five mutations in surface glycoprotein (Spike) of SARS-CoV-2 among Indian isolates and their impact on protein dynamics

Chand GB, Banerjee A, Azad GK.

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Selenium and RNA Virus Interactions: Potential Implications for SARS-CoV-2 Infection (COVID-19)

Hiffler L, Rakotoambinina B.

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Corrigendum: Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System

Xu R, Shi M, Li J, Song P, Li N.

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Serum SARS-COV-2 Nucleocapsid Protein: A Sensitivity and Specificity Early Diagnostic Marker for SARS-COV-2 Infection

Li T, Wang L, Wang H, Li X, Zhang S, Xu Y, Wei W.

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Effective Anti-SARS-CoV-2 RNA Dependent RNA Polymerase Drugs Based on Docking Methods: The Case of Milbemycin, Ivermectin, and Baloxavir Marboxil

Daghir Janabi AH.

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A numerical solution by alternative Legendre polynomials on a model for novel coronavirus (COVID-19)

Hashemizadeh E, Ebadi MA.

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Variations in SARS-CoV-2 Spike Protein Cell Epitopes and Glycosylation Profiles During Global Transmission Course of COVID-19

Xu W, Wang M, Yu D, Zhang X.

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Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

Shen L, Dien Bard J, Biegel JA, Judkins AR, Gai X.

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Is There a Link Between the Pathogenic Human Coronavirus Envelope Protein and Immunopathology? A Review of the Literature

Schoeman D, Fielding BC.

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Artificial Light at Night (ALAN): A Potential Anthropogenic Component for the COVID-19 and HCoVs Outbreak

Khan ZA, Yumnamcha T, Mondal G, Devi SD, Rajiv C, Labala RK, Sanjita Devi H, Chattoraj A.

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Screening of FDA Approved Drugs Against SARS-CoV-2 Main Protease: Coronavirus Disease

Balakrishnan V, Lakshminarayanan K.

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Epidemiology, Genomic Structure, the Molecular Mechanism of Injury, Diagnosis and Clinical Manifestations of Coronavirus Infection: An Overview

Prasad N, Gopalakrishnan N, Sahay M, Gupta A, Agarwal SK; COVID-19 Working Group of Indian Society of Nephrology.

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Conventional PCR Assisted Single-Component Assembly of Spherical Nucleic Acids for Simple Colorimetric Detection of SARS-CoV-2

Karami A, Hasani M, Jalilian FA, Ezati R.

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The recent advancement of low-dimensional nanostructured materials for drug delivery and drug sensing application: A brief review

Rahman H, Hossain MR, Ferdous T.

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SARS-CoV-2 and the Possible Role of Raf/MEK/ERK Pathway in Viral Survival: Is This a Potential Therapeutic Strategy for COVID-19?

Ghasemnejad-Berenji M, Pashapour S.

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Molecular and serological characterization of SARS-CoV-2 infection among COVID-19 patients

Li L, Liang Y, Hu F, Yan H, Li Y, Xie Z, Huang L, Zhao J, Wan Z, Wang H, Shui J, Cai W, Tang S.

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Novel cyclohexanone compound as a potential ligand against SARS-CoV-2 main-protease

Basu S, Veeraraghavan B, Ramaiah S, Anbarasu A.

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New putative insights into neprilysin (NEP)-dependent pharmacotherapeutic role of roflumilast in treating COVID-19

El Tabaa MM, El Tabaa MM.

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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium

Jacob F, Pather SR, Huang WK, Zhang F, Wong SZH, Zhou H, Cubitt B, Fan W, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, Carlos de la Torre J, Ming GL.

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SARS-CoV-2 induces a more robust innate immune response and replicates less efficiently than SARS-CoV in the human intestines: an ex vivo study with implications on pathogenesis of COVID-19

Chu H, Fuk-Woo Chan J, Wang Y, Tsz-Tai Yuen T, Chai Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Hou Y, Cai JP, Zhang AJ, Zhou J, Yuan S, Kai-Wang To K, Fan-Ngai Hung I, Cheung TT, Tsui-Lin Ng A, Hau-Yee Chan I, Yu-Hong Wong I, Ying-Kit Law S, Chi-Chung Foo D, Leung WK, Yuen KY.

Abstract:

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The antibody response to the glycan α-Gal correlates with COVID-19 disease symptoms

Urra JM, Ferreras-Colino E, Contreras M, Cabrera CM, Fernández de Mera IG, Villar M, Cabezas-Cruz A, Gortázar C, de la Fuente J.

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In silico molecular docking: Evaluation of coumarin based derivatives against SARS-CoV-2

Chidambaram SK, Ali D, Alarifi S, Radhakrishnan S, Akbar I.

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The expression of SARS-CoV-2 receptor ACE2 and CD147, and protease TMPRSS2 in human and mouse brain cells and mouse brain tissues

Qiao J, Li W, Bao J, Peng Q, Wen D, Wang J, Sun B.

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An in-silico evaluation of COVID-19 main protease with clinically approved drugs

Tachoua W, Kabrine M, Mushtaq M, Ul-Haq Z.

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Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro

Akaberi D, Krambrich J, Ling J, Luni C, Hedenstierna G, Järhult JD, Lennerstrand J, Lundkvist Å.

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SARS-CoV-2 variant tracing within the first COVID-19 clusters in Northern Germany

Pfefferle S, Günther T, Kobbe R, Czech-Sioli M, Nörz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch JK, Lütgehetmann M, Fischer N.

Abstract:

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Genetics and genomics of SARS-CoV-2: A review of the literature with the special focus on genetic diversity and SARS-CoV-2 genome detection

Rahimi A, Mirzazadeh A, Tavakolpour S.

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Severe SARS-CoV-2 Disease In The Context Of A NFκB2 Loss-Of-Function Pathogenic Variant

Abraham RS, Marshall JM, Kuehn HS, Rueda CM, Gibbs A, Guider W, Stewart C, Rosenzweig SD, Wang H, Jean S, Peeples M, King T, Hunt WG, Honegger JR, Ramilo O, Mustillo PJ, Mejias A, Ardura MI, Shimamura M.

Abstract:

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Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

Klimczak LJ, Randall TA, Saini N, Li JL, Gordenin DA.

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Molecular Simulations and Network Modeling Reveal an Allosteric Signaling in the SARS-CoV-2 Spike Proteins

Verkhivker GM.

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Systemic effects of missense mutations on SARS-CoV-2 spike glycoprotein stability and receptor-binding affinity

Teng S, Sobitan A, Rhoades R, Liu D, Tang Q.

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Biological Factors Linking ApoE ε4 Variant and Severe COVID-19

Inal J.

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Genomic diversity and evolution, diagnosis, prevention, and therapeutics of the pandemic COVID-19 disease

Hoque MN, Chaudhury A, Akanda MAM, Hossain MA, Islam MT.

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Susceptibility of swine cells and domestic pigs to SARS-CoV-2

Meekins DA, Morozov I, Trujillo JD, Gaudreault NN, Bold D, Carossino M, Artiaga BL, Indran SV, Kwon T, Balaraman V, Madden DW, Feldmann H, Henningson J, Ma W, Balasuriya UBR, Richt AJA.

Abstract:

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Effective Immune Functions of Micronutrients against SARS-CoV-2

Junaid K, Ejaz H, Abdalla AE, Abosalif KOA, Ullah MI, Yasmeen H, Younas S, Hamam SSM, Rehman A.

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Interaction of Human ACE2 to Membrane-Bound SARS-CoV-1 and SARS-CoV-2 S Glycoproteins

Anand SP, Chen Y, Prévost J, Gasser R, Beaudoin-Bussières G, Abrams CF, Pazgier M, Finzi A.

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Targeting the SphK-S1P-SIPR Pathway as a Potential Therapeutic Approach for COVID-19

McGowan EM, Haddadi N, Nassif NT, Lin Y.

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SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion

Gambichler T, Reuther J, Stücker M, Stranzenbach R, Torres-Reyes C, Schlottmann R, Schmidt WE, Hayajneh R, Sriram A, Becker JC.

Abstract:

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Molecular and functional resemblance of dexamethasone and quercetin: A paradigm worth exploring in dexamethasone-nonresponsive COVID-19 patients

Pawar A, Pal A.

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Potential COVID-19 papain-like protease PL(pro) inhibitors: repurposing FDA-approved drugs

Kouznetsova VL, Zhang A, Tatineni M, Miller MA, Tsigelny IF.

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Preparing for the Unprecedented: The Association of Biomolecular Resource Facilities (ABRF) Community Coronavirus Disease 2019 (COVID-19) Pandemic Response Part 1: Efforts to Sustainably Ramp Down Core Facility Activities

Kigenyi J, Mische SM, Porter DM, Rappoport JZ, Vinard A.

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SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition

Nelde A, Bilich T, Heitmann JS, Maringer Y, Salih HR, Roerden M, Lübke M, Bauer J, Rieth J, Wacker M, Peter A, Hörber S, Traenkle B, Kaiser PD, Rothbauer U, Becker M, Junker D, Krause G, Strengert M, Schneiderhan-Marra N, Templin MF, Joos TO, Kowalewski DJ, Stos-Zweifel V, Fehr M, Rabsteyn A, Mirakaj V, Karbach J, Jäger E, Graf M, Gruber LC, Rachfalski D, Preuß B, Hagelstein I, Märklin M, Bakchoul T, Gouttefangeas C, Kohlbacher O, Klein R, Stevanović S, Rammensee HG, Walz JS.

Abstract:

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Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy

Caldas LA, Carneiro FA, Higa LM, Monteiro FL, da Silva GP, da Costa LJ, Durigon EL, Tanuri A, de Souza W.

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The inhibitory effect of some natural bioactive compounds against SARS-CoV-2 main protease: insights from molecular docking analysis and molecular dynamic simulation

Abdelrheem DA, Ahmed SA, Abd El-Mageed HR, Mohamed HS, Rahman AA, Elsayed KNM, Ahmed SA.

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Development and Optimization of In-house ELISA for Detection of Human IgG Antibody to SARS-CoV-2 Full Length Spike Protein

Alandijany TA, El-Kafrawy SA, Tolah AM, Sohrab SS, Faizo AA, Hassan AM, Alsubhi TL, Othman NA, Azhar EI.

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Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis

Tutusaus A, Marí M, Ortiz-Pérez JT, Nicolaes GAF, Morales A, García de Frutos P.

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IL6-mediated HCoV-host interactome regulatory network and GO/Pathway enrichment analysis

Politano G, Benso A.

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Chemosensory Dysfunction in COVID-19: Integration of Genetic and Epidemiological Data Points to D614G Spike Protein Variant as a Contributing Factor

Butowt R, Bilinska K, Von Bartheld CS.

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Genomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil

Nascimento VAD, Corado ALG, Nascimento FOD, Costa ÁKAD, Duarte DCG, Luz SLB, Gonçalves LMF, Jesus MS, Costa CFD, Delatorre E, Naveca FG.

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Arenaria kansuensis attenuates pulmonary fibrosis in mice via the activation of Nrf2 pathway and the inhibition of NF-kB/TGF-beta1/Smad2/3 pathway

Cui Y, Xin H, Tao Y, Mei L, Wang Z.

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Identification of potential inhibitors of coronavirus hemagglutinin-esterase using molecular docking, molecular dynamics simulation and binding free energy calculation

Patel CN, Kumar SP, Pandya HA, Rawal RM.

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DNA Methylation Architecture of the ACE2 gene in Nasal Cells

Cardenas A, Rifas-Shiman SL, Sordillo JE, DeMeo DL, Baccarelli AA, Hivert MF, Gold DR, Oken E.

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Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein

Heinzelman P, Romero PA.

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Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors

Ma C, Hu Y, Townsend JA, Lagarias PI, Marty MT, Kolocouris A, Wang J.

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Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, Iwasawa K, Crary J, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ.

Abstract:

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Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Gazumyan A, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, Nussenzweig MC, Sheahan TP.

Abstract:

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An evolutionary portrait of the progenitor SARS-CoV-2 and its dominant offshoots in COVID-19 pandemic

Kumar S, Tao Q, Weaver S, Sanderford M, Caraballo-Ortiz MA, Sharma S, Pond SLK, Miura S.

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SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

Jack A, Ferro LS, Trnka MJ, Wehri E, Nadgir A, Costa K, Schaletzky J, Yildiz A.

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SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism

Shi M, Wang L, Fontana P, Vora S, Zhang Y, Fu TM, Lieberman J, Wu H.

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Ambroxol Hydrochloride Inhibits the Interaction between Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein's Receptor Binding Domain and Recombinant Human ACE2

Olaleye OA, Kaur M, Onyenaka CC.

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Self-assembling nanoparticles presenting receptor binding domain and stabilized spike as next-generation COVID-19 vaccines

He L, Lin X, Wang Y, Abraham C, Sou C, Ngo T, Zhang Y, Wilson IA, Zhu J.

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In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein

Perez-Miller S, Patek M, Moutal A, Cabel CR, Thorne CA, Campos SK, Khanna R.

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Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells

Sagar S, Rathinavel AK, Lutz WE, Struble LR, Khurana S, Schnaubelt AT, Mishra NK, Guda C, Broadhurst MJ, Reid SPM, Bayles KW, Borgstahl GEO, Radhakrishnan P.

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The flexibility of ACE2 in the context of SARS-CoV-2 infection

Barros EP, Casalino L, Gaieb Z, Dommer AC, Wang Y, Fallon L, Raguette L, Belfon K, Simmerling C, Amaro RE.

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A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro

Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B.

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Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection

Rosenke K, Meade-White K, Letko MC, Clancy C, Hansens F, Liu Y, Okumura A, Tang-Huau TL, Li R, Saturday G, Feldmann F, Scott D, Wang Z, Munster V, Jarvis M, Feldmann H.

Abstract:

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Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801

Wahl A, Gralinski L, Johnson C, Yao W, Kovarova M, Dinnon K, Liu H, Madden V, Krzystek H, De C, White K, Schäfer A, Zaman T, Leist S, Grant P, Gully K, Askin F, Browne E, Jones C, Pickles R, Baric R, Garcia JV.

Abstract:

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Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in Phospholipid Bilayers

Hong M, Mandala V, McKay M, Shcherbakov A, Dregni A, Kolocouris A.

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Integrated genomic view of SARS-CoV-2 in India

Kumar P, Pandey R, Sharma P, Dhar MS, A V, Uppili B, Vashisht H, Wadhwa S, Tyagi N, Fatihi S, Sharma U, Singh P, Lall H, Datta M, Gupta P, Saini N, Tewari A, Nandi B, Kumar D, Bag S, Gahlot D, Rathore S, Jatana N, Jaiswal V, Gogia H, Madan P, Singh S, Singh P, Dash D, Bala M, Kabra S, Singh S, Mukerji M, Thukral L, Faruq M, Agrawal A, Rakshit P.

Abstract:

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Discordance Between Radiologic Findings and Molecular Testing in Patients With Underlying Hematologic Malignancy and Coronavirus Disease 2019

Raja M, Natori Y, Chandorkar A, Camargo JF, Simkins J, Andrews D, Bradley T, Watts J, Komanduri K, Morris MI, Fishman JE.

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Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li J, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team, Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ.

Abstract:

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High-resolution structures of the SARS-CoV-2 2'-O-methyltransferase reveal strategies for structure-based inhibitor design

Rosas-Lemus M, Minasov G, Shuvalova L, Inniss NL, Kiryukhina O, Brunzelle J, Satchell KJF.

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The role of host defences in Covid 19 and treatments thereof

Dattilo M.

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Role of SARS-CoV-2 in Altering the RNA-Binding Protein and miRNA-Directed Post-Transcriptional Regulatory Networks in Humans

Srivastava R, Daulatabad SV, Srivastava M, Janga SC.

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Sex and SP-A2 Dependent NAD(H) Redox Alterations in Mouse Alveolar Macrophages in Response to Ozone Exposure: Potential Implications for COVID-19

Xu HN, Lin Z, Gandhi CK, Amatya S, Wang Y, Li LZ, Floros J.

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Identification of Novel Hypothalamic MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating ACE2 and TMPRSS2 Expression: An In Silico Analysis

Mukhopadhyay D, Mussa BM.

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Host Immune Response Driving SARS-CoV-2 Evolution

Wang R, Hozumi Y, Zheng YH, Yin C, Wei GW.

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SARS-CoV-2 receptor ACE2 is expressed in human conjunctival tissue, especially in diseased conjunctival tissue

Li S, Li D, Fang J, Liu Q, Cao W, Sun X, Xu G.

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Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

Piccoli L, Park YJ, Tortorici MA, Czudnochowski N, Walls AC, Beltramello M, Silacci-Fregni C, Pinto D, Rosen LE, Bowen JE, Acton OJ, Jaconi S, Guarino B, Minola A, Zatta F, Sprugasci N, Bassi J, Peter A, De Marco A, Nix JC, Mele F, Jovic S, Rodriguez BF, Gupta SV, Jin F, Piumatti G, Lo Presti G, Pellanda AF, Biggiogero M, Tarkowski M, Pizzuto MS, Cameroni E, Havenar-Daughton C, Smithey M, Hong D, Lepori V, Albanese E, Ceschi A, Bernasconi E, Elzi L, Ferrari P, Garzoni C, Riva A, Snell G, Sallust

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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

Yurkovetskiy L, Wang X, Pascal KE, Tomkins-Tinch C, Nyalile TP, Wang Y, Baum A, Diehl WE, Dauphin A, Carbone C, Veinotte K, Egri SB, Schaffner SF, Lemieux JE, Munro JB, Rafique A, Barve A, Sabeti PC, Kyratsous CA, Dudkina NV, Shen K, Luban J.

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Lung Expression of Human ACE2 Sensitizes the Mouse to SARS-CoV-2 Infection

Han K, Blair RV, Iwanaga N, Liu F, Russell-Lodrigue KE, Qin Z, Midkiff CC, Golden NA, Doyle-Meyers LA, Kabir ME, Chandler KE, Cutrera KL, Ren M, Monjure CJ, Lehmicke G, Fischer T, Beddingfield B, Wanek AG, Birnbaum A, Maness NJ, Roy CJ, Datta PK, Rappaport J, Kolls JK, Qin X.

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Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia

Liu A, Zhang X, Li R, Zheng M, Yang S, Dai L, Wu A, Hu C, Huang Y, Xie M, Chen Q.

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COVID-19 survival associates with the immunoglobulin response to the SARS-CoV-2 spike Receptor Binding Domain

Secchi M, Bazzigaluppi E, Brigatti C, Marzinotto I, Tresoldi C, Rovere-Querini P, Poli A, Castagna A, Scarlatti G, Zangrillo A, Ciceri F, Piemonti L, Lampasona V.

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Flight-Associated Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Corroborated by Whole-Genome Sequencing

Speake H, Phillips A, Chong T, Sikazwe C, Levy A, Lang J, Scalley B, Speers DJ, Smith DW, Effler P, McEvoy SP.

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The Antibody Response to SARS-CoV-2 Infection

Hueston L, Kok J, Guibone A, McDonald D, Hone G, Goodwin J, Carter I, Basile K, Sandaradura I, Maddocks S, Sintchenko V, Gilroy N, Chen S, Dwyer DE, O'Sullivan MVN.

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Genomic Epidemiology and Recent Update on Nucleic Acid-Based Diagnostics for COVID-19

Rabaan AA, Al-Ahmed SH, Sah R, Al-Tawfiq JA, Haque S, Harapan H, Arteaga-Livias K, Aldana DKB, Kumar P, Dhama K, Rodriguez-Morales AJ.

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MAIT cell activation and dynamics associated with COVID-19 disease severity

Parrot T, Gorin JB, Ponzetta A, Maleki KT, Kammann T, Emgård J, Perez-Potti A, Sekine T, Rivera-Ballesteros O; Karolinska COVID-19 Study Group, Gredmark-Russ S, Rooyackers O, Folkesson E, Eriksson LI, Norrby-Teglund A, Ljunggren HG, Björkström NK, Aleman S, Buggert M, Klingström J, Strålin K, Sandberg JK.

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Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

Cheng MH, Zhang S, Porritt RA, Noval Rivas M, Paschold L, Willscher E, Binder M, Arditi M, Bahar I.

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HLA genetic polymorphisms and prognosis of patients with COVID-19

Lorente L, Martín MM, Franco A, Barrios Y, Cáceres JJ, Solé-Violán J, Perez A, Marcos Y Ramos JA, Ramos-Gómez L, Ojeda N, Jiménez A; Working Group on COVID-19 Canary ICU; Annex. Members of the BIOMEPOC group.

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Development of a Clinical MALDI-ToF Mass Spectrometry Assay for SARS-CoV-2: Rational Design and Multi-Disciplinary Team Work

Iles RK, Zmuidinaite R, Iles JK, Carnell G, Sampson A, Heeney JL.

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SARS-CoV-2: From Structure to Pathology, Host Immune Response and Therapeutic Management

Mihaescu G, Chifiriuc MC, Iliescu C, Vrancianu CO, Ditu LM, Marutescu LG, Grigore R, Berteșteanu Ș, Constantin M, Gradisteanu Pircalabioru G.

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Mitochondrial Glutathione: Recent Insights and Role in Disease

Marí M, de Gregorio E, de Dios C, Roca-Agujetas V, Cucarull B, Tutusaus A, Morales A, Colell A.

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Design of novel viral attachment inhibitors of the spike glycoprotein (S) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) through virtual screening and dynamics

Rahman Oany A, Mia M, Pervin T, Junaid M, Zahid Hosen SM, Moni MA.

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Neprilysin expression and functions in development, ageing and disease

Nalivaeva NN, Zhuravin IA, Turner AJ.

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Transcription-based drug repurposing for COVID-19

Killick R, Ballard C, Doherty P, Williams G.

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Biased mutation and selection in RNA viruses

Kustin T, Stern A.

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COVID-19: Significance of antibodies

Assadiasl S, Fatahi Y, Zavvar M, Nicknam MH.

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A bioinformatic prediction of antigen presentation from SARS-CoV-2 spike protein revealed a theorical correlation of HLA-DRB1*01 with COVID-19 fatality in Mexican population: an ecological approach

Romero-López JP, Carnalla-Cortés M, Pacheco-Olvera DL, Ocampo-Godínez JM, Oliva-Ramírez J, Moreno-Manjón J, Bernal-Alferes B, López-Olmedo N, García-Latorre E, Domínguez-López ML, Reyes-Sandoval A, Jiménez-Zamudio L.

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Genomic characterization and phylogenetic evolution of the SARS-CoV-2

Zhang RH, Ai X, Liu Y, Li CH, Zhang HL.

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Superiority of cilostazol among antiplatelet FDA-approved drugs against COVID 19 M(pro) and spike protein: Drug repurposing approach

Abosheasha MA, El-Gowily AH.

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Understanding Selenium and Glutathione as Antiviral Factors in COVID-19: Does the Viral M(pro) Protease Target Host Selenoproteins and Glutathione Synthesis?

Taylor EW, Radding W.

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Germ-Free Mice Under Two-Layer Textiles Are Fully Protected From Bacteria in Sprayed Microdroplets: A Functional in vivo Test Method of Facemask/Filtration Materials

Rodriguez-Palacios A, Conger M, Cominelli F.

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Computational biophysical characterization of the SARS-CoV-2 spike protein binding with the ACE2 receptor and implications for infectivity

Chowdhury R, Boorla VS, Maranas CD.

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An immersive journey to the molecular structure of SARS-CoV-2: Virtual reality in COVID-19

Calvelo M, Piñeiro Á, Garcia-Fandino R.

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Toward Understanding Molecular Bases for Biological Diversification of Human Coronaviruses: Present Status and Future Perspectives

Koma T, Adachi S, Doi N, Adachi A, Nomaguchi M.

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Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone

Kuzmin K, Adeniyi AE, DaSouza AK Jr, Lim D, Nguyen H, Molina NR, Xiong L, Weber IT, Harrison RW.

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Pharmacophore based virtual screening, molecular docking, molecular dynamics and MM-GBSA approach for identification of prospective SARS-CoV-2 inhibitor from natural product databases

Kumar BK, Faheem, Sekhar KVGC, Ojha R, Prajapati VK, Pai A, Murugesan S.

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Delayed Diagnosis and Treatment of a Critically Ill Patient with Infective Endocarditis Due to a False-Positive Molecular Diagnostic Test for SARS-CoV-2

Schizas N, Michailidis T, Samiotis I, Patris V, Papakonstantinou K, Argiriou M, Dedeilias P.

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Characterizing COVID-19 maternal-fetal transmission and placental infection using comprehensive molecular pathology

Schwartz DA, Thomas KM.

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Molecular Architecture of the SARS-CoV-2 Virus

Yao H, Song Y, Chen Y, Wu N, Xu J, Sun C, Zhang J, Weng T, Zhang Z, Wu Z, Cheng L, Shi D, Lu X, Lei J, Crispin M, Shi Y, Li L, Li S.

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The structure-activity relationship of the interactions of SARS-CoV-2 spike glycoproteins with glucuronomannan and sulfated galactofucan from Saccharina japonica

Jin W, Zhang W, Mitra D, McCandless MG, Sharma P, Tandon R, Zhang F, Linhardt RJ.

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Rescue of SARS-CoV-2 from a Single Bacterial Artificial Chromosome

Ye C, Chiem K, Park JG, Oladunni F, Platt RN 2nd, Anderson T, Almazan F, de la Torre JC, Martinez-Sobrido L.

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Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage

Shi TH, Huang YL, Chen CC, Pi WC, Hsu YL, Lo LC, Chen WY, Fu SL, Lin CH.

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Leukotrienes, a potential target for Covid-19

Citron F, Perelli L, Deem AK, Genovese G, Viale A.

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Venous thromboembolism and bleeding in critically ill COVID-19 patients treated with higher than standard low molecular weight heparin doses and aspirin: A call to action

Pavoni V, Gianesello L, Pazzi M, Stera C, Meconi T, Frigieri FC.

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Comparison of 2 fully automated tests detecting antibodies against nucleocapsid N and spike S1/S2 proteins in COVID-19

Flinck H, Rauhio A, Luukinen B, Lehtimäki T, Haapala AM, Seiskari T, Aittoniemi J.

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COVID-19 Makes B Cells Forget, but T Cells Remember

Cañete PF, Vinuesa CG.

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Covid-19: from structure to therapeutic targeting in studying approved drugs and local DNA vaccination

Wang Z, Hong X, Wang H, Liu J, Liu JP.

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Comparison of two automated immunoassays for the detection of SARS-CoV-2 nucleocapsid antibodies

Hubbard JA, Geno KA, Khan J, Szczepiorkowski ZM, de Gijsel D, Ovalle AA, AlSalman AS, Gallagher TL, Johnston AA, Tibbetts AR, Vital SE, Cervinski MA, Nerenz RD.

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Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine

Schloer S, Brunotte L, Goretzko J, Mecate-Zambrano A, Korthals N, Gerke V, Ludwig S, Rescher U.

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Evaluation of Regeneration Processes for Filtering Facepiece Respirators in Terms of the Bacteria Inactivation Efficiency and Influences on Filtration Performance

He W, Guo Y, Gao H, Liu J, Yue Y, Wang J.

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Naturally activated adaptive immunity in COVID-19 patients

Yang X, Dai T, Zhou X, Qian H, Guo R, Lei L, Zhang X, Zhang D, Shi L, Cheng Y, Hu J, Guo Y, Zhang B.

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An Overview of the Temporal Shedding of SARS-CoV-2 RNA in Clinical Specimens

Zhurakivska K, Troiano G, Pannone G, Caponio VCA, Lo Muzio L.

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Unraveling the Epidemiology, Geographical Distribution, and Genomic Evolution of Potentially Lethal Coronaviruses (SARS, MERS, and SARS CoV-2)

Masood N, Malik SS, Raja MN, Mubarik S, Yu C.

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Commentary: SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Djomkam ALZ, Olwal CO, Sala TB, Paemka L.

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Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System Conditions

Zhang Q, Yue Y, Tan H, Liu Y, Zeng Y, Xiao L.

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PI3Kδ Inhibition as a Potential Therapeutic Target in COVID-19

Palma G, Pasqua T, Silvestri G, Rocca C, Gualtieri P, Barbieri A, De Bartolo A, De Lorenzo A, Angelone T, Avolio E, Botti G.

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Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury

Chen X, Guo H, Qiu L, Zhang C, Deng Q, Leng Q.

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Innate Immune Responses to Highly Pathogenic Coronaviruses and Other Significant Respiratory Viral Infections

Ahmed-Hassan H, Sisson B, Shukla RK, Wijewantha Y, Funderburg NT, Li Z, Hayes D Jr, Demberg T, Liyanage NPM.

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Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design

Kames J, Holcomb DD, Kimchi O, DiCuccio M, Hamasaki-Katagiri N, Wang T, Komar AA, Alexaki A, Kimchi-Sarfaty C.

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Misconceptions of pathophysiology of happy hypoxemia and implications for management of COVID-19

Tobin MJ, Jubran A, Laghi F.

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